iGluR

Ionotropic glutamate receptors (iGluRs) are ligand-gated ion channels that are activated by the neurotransmitter glutamate.[1] They mediate the majority of excitatory synaptic transmission throughout the central nervous system and are key players in synaptic plasticity, which is important for learning and memory. iGluRs have been divided into four subtypes on the basis of their ligand binding properties (pharmacology) and sequence similarity: AMPA receptors, kainate receptors, NMDA receptors and delta receptors.

Cat. No.	Product name	CAS No.	Purity
T13456	(S)-Willardiine	21416-43-3	98%
T13456	(S)-Willardiine is present in the seeds of Acacia and Mimosa. (S)-Willardiine is an AMPA/kainate receptor agonist (EC50 = 44.8 μM).
T61813	AMPA receptor antagonist-3	923272-18-8	98%
T61813	AMPA receptor antagonist-3 is an AMPA receptor antagonist (patent US20070027143A1).
T10781	CGP 78608 hydrochloride	1135278-54-4	98%
T10781	CGP 78608 hydrochloride is a specific antagonist at the glycine binding site of the NMDA receptor (IC50 = 6 nM). CGP 78608 hydrochloride exhibits anticonvulsant ...
T62042	BDZ-g	732278-52-3	98%
T62042	BDZ-g is a potent and selective antagonist of AMPA receptor. BDZ-g can be used for the research of various neurological disorders involving excessive activity of...
T23490	UBP310	902464-46-4	98%
T23490	GLUK5 kainate receptor antagonist
T10307	AMPA receptor modulator-1	2036074-41-4	98%
T10307	AMPA receptor modulator-1 can be activated by glutamate, thereby modulating ion channels.
T21584	CP 465022 hydrochloride	199655-36-2	98%
T21584	CP 465022 hydrochloride is a potent, and selective noncompetitive antagonist of AMPA receptor with anticonvulsant activity. CP 465022 hydrochloride inhibits Kain...
T61068	AMPA receptor antagonist-2	732277-05-3	98%
T61068	AMPA receptor antagonist-2 is an AMPA receptor antagonist.
T16963	SYM 2081	31137-74-3	98%
T16963	SYM 2081 is a specific kainate receptor agonist with an IC50 value of 35 nM for [3H]-kainate binding. SYM 2081 depolarizes the muscle and reduces the EPSP amplit...
T3407	Rapastinel	117928-94-6	98%
T3407	Rapastinel (GLYX-13) is an N-methyl-D-aspartate receptor (NMDAR) modulator.
T6618	Orphenadrine Citrate	4682-36-4	98%
T6618	Orphenadrine Citrate is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects.
T12733	Rislenemdaz	808732-98-1	98%
T12733	Rislenemdaz (CERC-301) is an antagonist of the N-methyl-D-aspartate (NMDA) receptor subunit 2B (GluN2B).
T61518	TAK-653	1358751-06-0	98%
T61518	TAK-653, an AMPA receptor potentiator with minimal agonistic activity, produces an antidepressant-like effect with a favorable safety profile in rats.
TQ0289	LY450108	376594-67-1	98%
TQ0289	LY450108 is a potentiator of the AMPA receptor.
T20571	Cis-PDA	46026-75-9	98%
T20571	cis-PDA, a general ionotropic receptor antagonist, acts by blocking NMDA, AMPA, and kainate mediated responses. It also acts as a partial NMDA receptor agonist.
T3407L	Rapastinel acetate	491872-39-0	98%
T3407L	Rapastinel acetate is a modulator of N-methyl-D-aspartate (NMDA) receptor and a partial agonist of glycine site long-lasting antidepressant effects.
T15820	Mibampator	375345-95-2	98%
T15820	Mibampator is an effective and selective AMPA receptor potentiator.
T12187L	Naspm trihydrochloride	1049731-36-3	98%
T12187L	Naspm trihydrochloride is a synthetic analogue of Joro spider toxin and is an antagonist of calcium permeable AMPA (CP-AMPA) receptors.
T4096	Quinolinic acid	89-00-9
T4096	Quinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway.
T22542	1-Aminocyclobutanecarboxylic acid	22264-50-2
T22542	1-Aminocyclobutanecarboxylic acid is a NMDA receptor partial agonist. 1-Aminocyclobutanecarboxylic acid act at the glycine site, NR1[1].