direct

C.I. Direct Red 1, disodium salt is a dye.

Evans blue (C.I. 23860) is an azo dye, inhibits L-glutamate uptake via the membrane-bound excitatory amino acid transporter (EAAT).

Ferristatin II (Direct Black 38 free acid) is a polysulphonated dye and promotes the degradation of transferrin receptor-1 in vitro and in vivo.

Direct Black 38 is an azo dye.It induces unscheduled DNA synthesis in liver and micronucleus in bone marrow of rats in vivo[1].

Diphenyl Blue (Direct Blue 14) (Direct Blue 14) is used as a dye for a group of azo dye.

C.I. Direct Blue 2 is an agent of dye.

Direct Violet 1 (CCRIS 2413) is an agent of dye.

CI Direct Brown 2 is a direct dye. It is soluble in water and ionizable to form colored anions. It also can directly dye cellulose fibers or protein fibers.

Direct Blue 1 (Pontamine sky blue), a counterstain for background autofluorescence in immunofluorescence histochemistry, structurally resembles glutamate and operates as a potent, competitive VGLUT inhibitor, not impacting plasma membrane transporters. This compound stands out as the inaugural small molecule PrP ligand to inhibit Aβ binding.

C.I. Direct Black 17 is a compound of dye.

Direct Green 6 is a green dye.

Direct Red 80 (Sirius Red) is a tetra azo dye. It can be used to detect amyloid and can magnify the usual birefringence of collagen fibers in tissue sections.

Solaminrot 4B is an agent of dye.

Thioflavine S (Direct Yellow 7) is a fluorescent histochemical marker.

C.I. 24280 is a dye.

Brilliant Yellow (Direct Yellow 4) is a potent and selective VGLUT inhibitor, a dye that is photodegradable.

Congo Red (Direct Red 28) is an azo dye. It binding been used as a diagnostic test for the presence of amyloid in tissue sections.

2-NBDG is a fluorescent indicator for direct glucose uptake measurement. It is an indicator of cell viability.

Alizarin Cyanine Green F (NSC-41838) is an agent of green dye. It can be used to dye paper, chromed leather, wool, silk, and nylon (acid bath), to stain wood, and to color anodized aluminum, urea-melamine resin, and soap. It is used to color nylon 66 and/or nylon 6 nonabsorbable surgical sutures for use in general surgery and used for coloring drugs generally, including drugs intended for use in the area of the eye. Alizarin Cyanine Green F is also proposed for use in semi-permanent hair dye formulations as a direct dye at a maximum concentration of 0.3% in the finished cosmetic product.

5-ROX, SE ([5-Carboxy-X-rhodamine, succinimidyl ester] *Single isomer*) is a labeling reagen used in the preparation of charge-modified dye-labeled Dideoxynucleotide Triphosphates (ddNTP) to direct-load DNA sequencing.

eGFP circRNA, originally isolated from the jellyfish Aequorea victoria, is a reporter widely utilized for direct detection in mammalian cell culture due to its bright green fluorescence with an emission peak at 509 nm. It serves as an excellent tool for monitoring and optimizing transfection efficiency and is recommended as a positive control for circular RNA transfections.

TFMU-ADPr serves as a versatile substrate for assessing poly(ADP-ribose) glycohydrolase (PARG) activity, enabling direct measurement of total PAR hydrolase activity through the liberation of a fluorophore. Exhibiting exceptional reactivity, generality, stability, and usability, TFMU-ADPr is an effective tool for evaluating small-molecule inhibitors and investigating the regulation of ADP-ribosyl catabolic enzymes in vitro [1].

eGFP mRNA encodes the green fluorescent protein, originally derived from the jellyfish Aequorea victoria, and serves as a widely utilized direct detection reporter in mammalian cell culture. This protein produces a distinct bright green fluorescence, with an emission peak at 509 nm.

Chol-N3 is a bioorthogonal chol probe capable of integrating with super-resolution fluorescence microscopy (SRM) to enable direct nanoscale imaging of lipid heterogeneity on resting living cell surfaces [1]. As a click chemistry reagent with an azide group, Chol-N3 undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-bearing molecules and can also participate in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN group-containing molecules.

Methyl Green, a potent fluorescent dye, serves as a DNA stain for cells and electrophoretic gels. It facilitates direct measurement of viability via microscopy and flow cytometry, exhibiting peaks at 633 and 677 nm [1] [2]. For storage, it is imperative to protect Methyl Green from light.

C.I. 13900 is a dye that is a yellow powder. It is brown in concentrated sulfuric acid and bright brown when diluted. It is used for the dyeing of wool, silk, nylon and leather, as well as for the direct printing of trims on wool and silk fabrics.

The biology of highly reactive oxygen radical species is of great interest in many biomedical research disciplines, including neurodegeneration, aging, cancer, and infectious diseases.[1] There are a number of fluorescent reagents, such as 2,7-dichlorodihydrofluorescein (DCDHF), that can be used to detect free radicals, but they have significant limitations due to their facile oxidation by light and numerous non-radical oxidants such as hydrogen peroxide (H2O2). [2] HPF is a cell-permeable aromatic amino-fluorescein derivative that has little intrinsic fluorescence. [3] It undergoes oxidation only by highly reactive oxygen species (hROS) such as the hydroxyl radical, peroxynitrite, and hROS generated from a peroxidase/H2O2 system. It is inert to hypochlorite ion, nitric oxide, hydrogen peroxide (H2O2), superoxide, and other oxidants. Upon oxidation, HPF is converted to the highly fluorescent molecule fluorescein, with excitation/emission maxima of 490/515 nm, respectively, allowing the simple direct detection of highly reactive biological radicals.

7-Ethoxy-5-(trifluoromethyl)coumarin is a fluorogenic substrate for cytochrome P450s (CYPs).1Upon O-deethylation by CYPs, 7-hydroxy-4-(trifluoromethyl)coumarin (HFC) is released and its fluorescence can be used to quantify CYP activity. HFC displays excitation/emission maxima of 410/510 nm, respectively. 1.Buters, J.T.M., Schiller, C.D., and Chou, R.C.A highly sensitive tool for the assay of cytochrome P450 enzyme activity in rat, dog and man. Direct fluorescence monitoring of the deethylation of 7-ethoxy-4-trifluoromethylcoumarinBiochem. Pharmacol.46(9)1577-1584(1993)

Methyl Green Zinc Chloride, a potent fluorescent dye, is utilized for staining DNA in cells and electrophoretic gels. It serves as a direct measure of viability through microscopy and flow cytometry, exhibiting peaks at 633 and 677 nm [1] [2]. For storage, it should be protected from light.

Mca-RPPGFSAFK(Dnp)-OH, a fluorogenic substrate specifically designed for endothelin-converting enzyme-1 (ECE-1), enables the quantification of ECE-1 activity through its distinctive fluorescence signal. When ECE-1 cleaves this substrate, it releases 7-methoxycoumarin-4-acetyl (Mca), which exhibits excitation and emission maxima at 328 nm and 420 nm, respectively, allowing for the direct measurement of enzyme activity.