T19449 |
N-desmethyl Enzalutamide D6
|
T19449
|
98%
|
|
N-desmethyl Enzalutamide D6 is a deuterium labeled N-desmethyl Enzalutamide.
|
TMA1012 |
Ganoderiol F
|
114567-47-4
|
98%
|
|
Ganoderiol F has anti-inflammatory, cytotoxic and anti-HIV activity, it inhibits activity of topoisomerases in vitro, and it inhibits human immunodeficiency viru...
|
T14843 |
Bifluranol
|
34633-34-6
|
98%
|
|
Bifluranol is an anti-androgen.
|
T14675 |
BMS-564929
|
627530-84-1
|
98%
|
|
BMS-564929 is an agonist of androgen receptor (AR, Ki of 2.11±0.16 nM).
|
TN4774 |
Physalin A
|
23027-91-0
|
98%
|
|
Physalin A exerts anti-tumor activity in non-small cell lung cancer cell lines by suppressing JAK/STAT3 signaling, it inhibits androgen-independent prostate canc...
|
T10946 |
D4-abiraterone
|
154229-21-7
|
98%
|
|
D4-Abiraterone is an inhibitor of CYP17A1, 3b-hydroxysteroid dehydrogenase (3βHSD) and steroid 5a-reductase (SRD5A), the main metabolite of abiraterone. D4-Abira...
|
T15816 |
LY341495
|
201943-63-7
|
98%
|
|
LY341495 is an antagonist of metabotropic glutamate receptor (IC50s: 2.9 nM, 10 nM, 170 nM for mGluR-2, mGluR-3, mGluR-8, respectively).
|
T15749 |
LGD-2226
|
328947-93-9
|
98%
|
|
LGD-2226 is a selective and orally active androgen receptor modulator (EC50: 0.2 nM, Ki: 1.5 nM for the human androgen receptor). LGD-2226 can be used for muscle...
|
TN1061 |
Ganoderol B
|
104700-96-1
|
98%
|
|
Ganoderol B is a potent β ±-glucosidase and angiotensin-converting enzyme inhibitor, with an IC(50) of β ±-glucosidase is 119.8 uM. It may be useful in prostate ...
|
TN1663 |
Ganoderic acid DM
|
173075-45-1
|
98%
|
|
Ganoderic acid DM is an antiandrogenic osteoclastogenesis inhibitor, it especially suppresses the expression of c-Fos and nuclear factor of activated T cells c1 ...
|
T20625 |
Prochloraz
|
67747-09-5
|
98%
|
|
Prochloraz, a broad-spectrum contact imidazole fungicide, is used against several diseases in wheat, barley, and oleaginous plants but also for the treatment of ...
|
TN1067 |
Galloylpaeoniflorin
|
122965-41-7
|
98%
|
|
6'-O-Galloylpaeoniflorin (GPF) may be developed as a cytoprotector against ROS-mediated oxidative stress
|
T39695 |
ARD-2128
|
2222111-87-5
|
98%
|
|
ARD-2128 is a highly potent, orally bioavailable PROTAC degrader of androgen receptor (AR). ARD-2128 effectively reduces AR protein, suppresses AR-regulated gene...
|
T8860 |
DSRM-3716
|
58142-99-7
|
98%
|
|
Isoquinoline, 5-iodo- (9CI) is a potent and selective inhibitor of SARM1(IC50 = 75 nM) by preventing axonal degeneration and by allowing functional recovery of a...
|
T24943 |
VPC-14228
|
19983-28-9
|
98%
|
|
VPC-14228 is a specific AR-DBD inhibitor that acts by inhibiting both Y594A and Q592A mutants.
|
T67818 |
BMS-641988
|
|
98%
|
|
BMS-641988 is a novel nonsteroidal androgen receptor antagonist for the treatment of prostate cancer.
|
T2991 |
3,3'-Diindolylmethane
|
1968-05-4
|
98%
|
|
DIM (3, 3'-diindolylmethane), a small molecule compound, is a proposed Y preventive agent.
|
T8117 |
Metenolone acetate
|
434-05-9
|
98%
|
|
Methenolone acetate is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of anemia due to bone marrow failure.
|
T75129 |
Luxdegalutamide
|
2750830-09-0
|
98%
|
|
Luxdegalutamide is an orally available and effective protein degrader of protein hydrolysis-targeted chimeras (PROTAC).Luxdegalutamide degrades the wild-type and...
|
T6400 |
AZD3514
|
1240299-33-5
|
98%
|
|
AZD3514 is a potent and oral androgen receptor downregulator with Ki of 2.2 μM and has ability of reducing AR protein expression.Phase 1.
|