TQ0080 |
SU14813 maleate
|
849643-15-8
|
98%
|
|
SU14813 maleate is an inhibitor of multi-targeted receptor tyrosine kinases (IC50s: 2, 50, 4, 15 nM for VEGFR1, VEGFR2, PDGFRβ, and KIT).
|
TN1867 |
Licoricidin
|
30508-27-1
|
98%
|
|
Licoricidin, is a potent anti-metastatic agent, which can markedly inhibit the metastatic and invasive capacity of malignant prostate cancer cells.
|
TN4913 |
Riddelline
|
23246-96-0
|
98%
|
|
Riddelline is a potent genotoxic agent in vitro and induces significant elevations in unscheduled DNA synthesis and S-phase synthesis in rat liver.
|
T6036 |
Brivanib
|
649735-46-6
|
98%
|
|
Brivanib is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold against PDGFR-β. Phase 3.
|
TN1095 |
Ginsenoside Rk2
|
364779-14-6
|
98%
|
|
Ginsenoside Rk1 has anti-tumor, and anti-platelet aggregation activities.
|
T13178 |
Toceranib
|
356068-94-5
|
98%
|
|
Toceranib phosphate is an orally active inhibitor of tyrosine kinase (RTK) receptor, and it potently inhibits PDGFR, VEGFR, and Kit(with Kis of 5 and 6 nM for PD...
|
T13156 |
TG 100572
|
867334-05-2
|
98%
|
|
TG 100572 is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 ...
|
T6003 |
GSK1904529A
|
1089283-49-7
|
98%
|
|
GSK1904529A is a specific inhibitor of IGF-1R (IC50=27 nM) and IR(IC50=25 nM) .
|
TN5050 |
Sprengerinin C
|
88861-91-0
|
98%
|
|
Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and angiogenesis and induction of apoptosis, it can st...
|
TN4748 |
Penduletin
|
569-80-2
|
98%
|
|
Penduletin has anti-inflammatory,anti-tumor cells, and anti-bacterical activities,it inhibits growth of the Gram-negative pathogen neisseria gonorrhoeae. Pendule...
|
T12145 |
N-Desethyl Sunitinib
|
356068-97-8
|
98%
|
|
N-Desethyl Sunitinib is a sunitinib metabolite.
|
T23554 |
(Z)-FeCP-oxindole
|
1137967-28-2
|
98%
|
|
(Z)-FeCP-oxindole is a selective inhibitor of VEGFR2 with an IC50 of 200 nM for human. (Z)-FeCP-oxindole shows anticancer activity.
|
TN5100 |
Taspine
|
602-07-3
|
98%
|
|
Taspine shows antitumor activity by modulating the EGFR signaling pathway of Erk1/2 and Akt in vitro and in vivo, it can inhibit growth and induce apoptosis of H...
|
T13157 |
TG 100801
|
867331-82-6
|
98%
|
|
TG 100801 is a prodrug to treat age-related macular degeneration. TG 100572 is a inhibitor of multi-targeted kinase(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4...
|
T9928 |
Ranibizumab
|
347396-82-1
|
98%
|
|
Ranibizumab is an antibody fragment without the Fc portion and affinity-matured to more strongly bind VEGF-A
|
TMA1743 |
Ergosterol peroxide
|
2061-64-5
|
98%
|
|
Ergosterol peroxide is an inhibitor of osteoclast differentiation, which has antiviral, trypanocidal, antitumor, and antiangiogenic actions, it can stimulate Fox...
|
T35331 |
Dovitinib (TKI258) Lactate
|
|
98%
|
|
|
T1991 |
ZM323881 hydrochloride
|
193000-39-4
|
98%
|
|
ZZZM 323881 hydrochloride is a potent and selective VEGFR2 inhibitor.
|
T26852 |
BMS-605541
|
639858-32-5
|
98%
|
|
BMS-605541 is a potent and selective inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2) kinase activity(Ki=49 nM).
|
T10123 |
VEGFR-2-IN-9
|
408502-06-7
|
98%
|
|
KDR-in-4 is an effective inhibitor of kinase insert domain-containing receptor (KDR/VEGFR2) (IC50: 7 nM).
|