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Ferroptosis

Ferroptosis is a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides, and is genetically and biochemically distinct from other forms of regulated cell death such as apoptosis.
Cat. No. Product name CAS No. Purity Chemical Structure
T60168 NCOA4 - 9a 2650557-72-3 98%
NCOA4 - 9a is a ferroptosis inhibitor.
T36404L PRLX-93936 HCL 1094210-96-4 98%
PRLX-93936 hcl is an analog of erastin and demonstrated synergistic effects against non-small cell lung cancer (NSCLC) cells with cisplatin.
T20819 Ammonium iron(III) citrate 1185-57-5
Ferric ammonium citrate is a biochemical.
T6954 PRIMA-1 5608-24-2
PRIMA-1 is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.
T1502 Vildagliptin 274901-16-5
Vildagliptin is a cyanopyrrolidine-based, orally bioavailable inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Vildagliptin's cyano moiet...
T1114 Ciclopirox olamine 41621-49-2 100%
Ciclopirox Olamine is a broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities.
T7092 NADPH tetrasodium salt 2646-71-1 100%
NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate (NADP+) and acts as an electron donor in various ...
T0935 Butylated hydroxytoluene 128-37-0 100%
Butylated Hydroxytoluene is an organic chemical composed of 4-methylphenol modified with tert-butyl groups at positions 2 and 6. Butylated hydroxytoluene (BHT) i...
T2870 Matrine 519-02-8 100%
Matrine, an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.
T4066 FIN56 1083162-61-1 95%
FIN56 is a specific inducer of ferroptosis.
T2858 Baicalein 491-67-8 95.79%
Baicalein is a xanthine oxidase inhibitor.
T6099 Setanaxib 1218942-37-0 96.72%
GKT137831 is a potent, specific dual NADPH oxidase (NOX1/4) inhibitor.
T6243 U-73122 112648-68-7 96.73%
U73122, an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.
T8375 ML-210 1360705-96-9 97%
ML-210 is a selective RAS and covalent glutathione peroxidase 4 (GPX4) inhibitor(GPX4, EC50 : 30 nM), with anti-cancer activity
T6947 Piperlongumine 20069-09-4 97.21%
Piperlongumine is a natural alkaloid from Piper longum L. It selectively kills cancer cells and strengthens the level of reactive oxygen species (ROS).
T1085 L-Glutathione reduced 70-18-8 97.37%
Glutathione is a tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved...
TJS1159 Chrysosplenetin 603-56-5 97.43%
1. Chrysosplenetin is a metabolic inhibitor of artemisinin.
T1516 Curcumin 458-37-7 97.51%
Curcumin is a phytopolylphenol pigment isolated from the plant Curcuma longa, commonly known as turmeric, with a variety of pharmacologic properties. Curcumin bl...
T5679 (E)-Ferulic acid 537-98-4 98%
Trans-Ferulic acid causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic facto...
T0423 Ethylenediaminetetraacetic acid trisodium salt 150-38-9 98%
Edetate Trisodiumis used to bind metal ions in the chelation therapy.
NCOA4 - 9a
T60168
NCOA4 - 9a is a ferroptosis inhibitor.
PRLX-93936 HCL
T36404L
PRLX-93936 hcl is an analog of erastin and demonstrated synergistic effects against non-small cell lung cancer (NSCLC) cells with cisplatin.
Ammonium iron(III) citrate
T20819
Ferric ammonium citrate is a biochemical.
PRIMA-1
T6954
PRIMA-1 is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.
Vildagliptin
T1502
Vildagliptin is a cyanopyrrolidine-based, orally bioavailable inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Vildagliptin's cyano moiet...
Ciclopirox olamine
T1114
Ciclopirox Olamine is a broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities.
NADPH tetrasodium salt
T7092
NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate (NADP+) and acts as an electron donor in various ...
Butylated hydroxytoluene
T0935
Butylated Hydroxytoluene is an organic chemical composed of 4-methylphenol modified with tert-butyl groups at positions 2 and 6. Butylated hydroxytoluene (BHT) i...
Matrine
T2870
Matrine, an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.
FIN56
T4066
FIN56 is a specific inducer of ferroptosis.
Baicalein
T2858
Baicalein is a xanthine oxidase inhibitor.
Setanaxib
T6099
GKT137831 is a potent, specific dual NADPH oxidase (NOX1/4) inhibitor.
U-73122
T6243
U73122, an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.
ML-210
T8375
ML-210 is a selective RAS and covalent glutathione peroxidase 4 (GPX4) inhibitor(GPX4, EC50 : 30 nM), with anti-cancer activity
Piperlongumine
T6947
Piperlongumine is a natural alkaloid from Piper longum L. It selectively kills cancer cells and strengthens the level of reactive oxygen species (ROS).
L-Glutathione reduced
T1085
Glutathione is a tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved...
Chrysosplenetin
TJS1159
1. Chrysosplenetin is a metabolic inhibitor of artemisinin.
Curcumin
T1516
Curcumin is a phytopolylphenol pigment isolated from the plant Curcuma longa, commonly known as turmeric, with a variety of pharmacologic properties. Curcumin bl...
(E)-Ferulic acid
T5679
Trans-Ferulic acid causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic facto...
Ethylenediaminetetraacetic acid trisodium salt
T0423
Edetate Trisodiumis used to bind metal ions in the chelation therapy.
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