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Cell Cycle/Checkpoint Ferroptosis

Ferroptosis

Ferroptosis is a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides, and is genetically and biochemically distinct from other forms of regulated cell death such as apoptosis.
Cat No. product name
T1765 ErastinHOT Erastin is a ferroptosis activator acting on mitochondrial VDAC. It induces ferroptotic cell death in vitro.
T2376 Liproxstatin-1 Liproxstatin-1 is a potent ferroptosis inhibitor.
T6500 Ferrostatin-1HOT Ferrostatin-1 is a potent ferroptosis inhibitor (EC50: 60 nM).
T1637 Deferoxamine MesylateHOT Deferoxamine is an iron-chelating agent that binds free iron in a stable complex. It also is an inhibitor of ferroptosis.
T5343 UAMC-3203 UAMC-3203 is a potent and selective Ferroptosis inhibitor (IC50: 12 nM).
T5523 Imidazole ketone erastin Imidazole ketone erastin (IKE) is an inducer of ferroptosis. It has inhibition of the system Xc- cystine/glutamate transporter.
T8662 UAMC-3203 hydrochloride UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.
T11631 iFSP1 iFSP1 is able to sensitize a variety of human cancer cell lines to the ferroptosis inducer, such as (1S,3R)-RSL3.iFSP1 is a potent, selective and glutathione-in...
Erastin HOT
T1765CAS 571203-78-6
Erastin is a ferroptosis activator acting on mitochondrial VDAC. It induces ferroptotic cell death in vitro.
Liproxstatin-1
T2376CAS 950455-15-9
Liproxstatin-1 is a potent ferroptosis inhibitor.
Ferrostatin-1 HOT
T6500CAS 347174-05-4
Ferrostatin-1 is a potent ferroptosis inhibitor (EC50: 60 nM).
Deferoxamine Mesylate HOT
T1637CAS 138-14-7
Deferoxamine is an iron-chelating agent that binds free iron in a stable complex. It also is an inhibitor of ferroptosis.
UAMC-3203
T5343CAS 2271358-64-4
UAMC-3203 is a potent and selective Ferroptosis inhibitor (IC50: 12 nM).
Imidazole ketone erastin
T5523CAS 1801530-11-9
Imidazole ketone erastin (IKE) is an inducer of ferroptosis. It has inhibition of the system Xc- cystine/glutamate transporter.
UAMC-3203 hydrochloride
T8662CAS 2271358-65-5
UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.
iFSP1
T11631CAS 150651-39-1
iFSP1 is able to sensitize a variety of human cancer cell lines to the ferroptosis inducer, such as (1S,3R)-RSL3.iFSP1 is a potent, selective and glutathione-in...