Adenosine Receptor

The adenosine receptors are a class of purinergic G protein-coupled receptors with adenosine as the endogenous ligand. There are four known types of adenosine receptors in humans: A1, A2A, A2B and A3; each is encoded by a different gene.

Cat. No.	Product name	CAS No.	Purity
T16158	PF-02575799	863491-70-7	98%
PF-02575799 is an inhibitor of microsomal triglyceride transfer protein (MTP) (IC50: 0.77±0.29 nM).
T27509	GW-493838	253124-46-8	98%
GW-493838 is a potent adenosine A1A receptor agonist for the treatment of dyslipidemia and neuropathic pain, with analgesic effects on post-herpetic neuralgia or...
T22031	ANR 94	634924-89-3	98%
ANR94 is a potent and selective adenosine A 2A receptor (AA 2A R) antagonist with an K i of 46 nM for hAA 2A R. ANR94 has the potential for the research of Parki...
T11762	Kira8 Hydrochloride	2250019-92-0	98%
Kira8 Hydrochloride is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.
TQ0136	GR79236	124555-18-6	98%
GR79236 is an effective and selective adenosine A1 receptor agonist (Ki: 3.1 nM) that has analgesic and anti-inflammatory actions.
T13008	ST3932	1246018-21-2	98%
ST3932 is a ST1535 metabolite, is a adenosine A2A receptor antagonist(Kis of 8 nM and 33 nM for A2A and A1 receptors, respectively).
T16281	Nelonicline	1026134-63-3	98%
Nelonicline is a selective agonist of neuronal nicotinic receptors.
T12163	N6-(2-Phenylethyl)adenosine	20125-39-7	98%
N6-(2-Phenylethyl)adenosine is an adenosine derivative and an agonist of adenosine receptors with Ki values of 11.8 nM and 30.1 nM for rat and human A1.
T21620	2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine	133240-06-9	98%
2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine is an adenosine receptor antagonist.
T28861	ST-1535	496955-42-1	98%
ST 1535 is a potent and orally active antagonist of A2A adenosine receptor with antiparkinsonian activity and antitremorigenic effects. ST 1535 exhibits the pote...
T15418	GS-6201	752222-83-6	98%
GS-6201 is a selective antagonist of adenosine A2B receptor. GS-6201 shows high affinity and selectivity for the human adenosine A2B receptors (Ki: 22 nM). GS-62...
T37792	A2A receptor antagonist 1	443103-97-7	98%
A2A receptor antagonist 1 is an antagonist of both adenosine A2A receptor and A1 receptor with Kis of 4 and 264 nM, respectively.
T37793	A2B receptor antagonist 2	784-90-7	98%
A2B receptor antagonist 2 is an antagonist of adenosine receptor A2B (Ki = 2.30 μM for rA1, 6.8 μM for rA2A, 3.44 μM for hA2B).
T27629	ISAM-140	932191-62-3	98%
ISAM-140 is a potent and highly selective antagonist of A2B adenosine receptor.
T23016	MRS1220	183721-15-5	98%
MRS1220, a highly potent and selective human A3 adenosine receptor (hA3AR) antagonist with a Ki of 0.59 nM, has therapeutic potential for the research of disease...
T16140	MRS 1754	264622-58-4	98%
MRS 1754 is a selective antagonist radioligand for the A2B adenosine receptor. It has a very low affinity for A1 and A3 receptors of both humans and rats.
T23201	PSB 1115	152529-79-8	98%
human A2B adenosine receptor antagonist
T29112	VPC171	1018830-99-3	98%
VPC171 is a positive allosteric modulator (PAM) of the adenosine A1 receptor (A1R).
T8613	1-Ethyl-6-aminouracil	41862-09-3
1-Ethyl-6-aminouracil is an intermediate in the synthesis of a series of new substituted Xanthines which have high affinity and selectivity for the human adenosi...
T14078	AB928	2239273-34-6	100%
AB928 is an orally bioavailable, selective dual adenosine receptor (A2aR/A2bR) antagonist. It has immunomodulatory activity[1].

Cat. No.

Product name

CAS No.

Purity

Chemical Structure

T16158

PF-02575799

863491-70-7

98%

PF-02575799 is an inhibitor of microsomal triglyceride transfer protein (MTP) (IC50: 0.77±0.29 nM).

T27509

GW-493838

253124-46-8

98%

GW-493838 is a potent adenosine A1A receptor agonist for the treatment of dyslipidemia and neuropathic pain, with analgesic effects on post-herpetic neuralgia or...

T22031

ANR 94

634924-89-3

98%

ANR94 is a potent and selective adenosine A 2A receptor (AA 2A R) antagonist with an K i of 46 nM for hAA 2A R. ANR94 has the potential for the research of Parki...

T11762

Kira8 Hydrochloride

2250019-92-0

98%

Kira8 Hydrochloride is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.

TQ0136

GR79236

124555-18-6

98%

GR79236 is an effective and selective adenosine A1 receptor agonist (Ki: 3.1 nM) that has analgesic and anti-inflammatory actions.

T13008

ST3932

1246018-21-2

98%

ST3932 is a ST1535 metabolite, is a adenosine A2A receptor antagonist(Kis of 8 nM and 33 nM for A2A and A1 receptors, respectively).

T16281

Nelonicline

1026134-63-3

98%

Nelonicline is a selective agonist of neuronal nicotinic receptors.

T12163

N6-(2-Phenylethyl)adenosine

20125-39-7

98%

N6-(2-Phenylethyl)adenosine is an adenosine derivative and an agonist of adenosine receptors with Ki values of 11.8 nM and 30.1 nM for rat and human A1.

T21620

2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine

133240-06-9

98%

2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine is an adenosine receptor antagonist.

T28861

ST-1535

496955-42-1

98%

ST 1535 is a potent and orally active antagonist of A2A adenosine receptor with antiparkinsonian activity and antitremorigenic effects. ST 1535 exhibits the pote...

T15418

GS-6201

752222-83-6

98%

GS-6201 is a selective antagonist of adenosine A2B receptor. GS-6201 shows high affinity and selectivity for the human adenosine A2B receptors (Ki: 22 nM). GS-62...

T37792

A2A receptor antagonist 1

443103-97-7

98%

A2A receptor antagonist 1 is an antagonist of both adenosine A2A receptor and A1 receptor with Kis of 4 and 264 nM, respectively.

T37793

A2B receptor antagonist 2

784-90-7

98%

A2B receptor antagonist 2 is an antagonist of adenosine receptor A2B (Ki = 2.30 μM for rA1, 6.8 μM for rA2A, 3.44 μM for hA2B).

T27629

ISAM-140

932191-62-3

98%

ISAM-140 is a potent and highly selective antagonist of A2B adenosine receptor.

T23016

MRS1220

183721-15-5

98%

MRS1220, a highly potent and selective human A3 adenosine receptor (hA3AR) antagonist with a Ki of 0.59 nM, has therapeutic potential for the research of disease...

T16140

MRS 1754

264622-58-4

98%

MRS 1754 is a selective antagonist radioligand for the A2B adenosine receptor. It has a very low affinity for A1 and A3 receptors of both humans and rats.

T23201

PSB 1115

152529-79-8

98%

human A2B adenosine receptor antagonist

T29112

VPC171

1018830-99-3

98%

VPC171 is a positive allosteric modulator (PAM) of the adenosine A1 receptor (A1R).

T8613

1-Ethyl-6-aminouracil

41862-09-3

1-Ethyl-6-aminouracil is an intermediate in the synthesis of a series of new substituted Xanthines which have high affinity and selectivity for the human adenosi...

T14078

AB928

2239273-34-6

100%