T10602 |
BRD 4354 ditrifluoroacetate
|
T10602
|
98%
|
|
BRD 4354 (ditrifluoroacetate) is a moderately potent inhibitor of HDAC5 and HDAC9 (IC50s: 0.85 and 1.88 μM).
|
T16805 |
RTS-V5
|
2285346-31-6
|
98%
|
|
RTS-V5 is a dual inhibitor of HDAC/proteasome (IC50s: 6.9, 18, 15, 0.27, 0.53 μM for HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, respectively).
|
T16415 |
Oxamflatin
|
151720-43-3
|
98%
|
|
Oxamflatin is an effective inhibitor of HDAC (IC50: 15.7 nM).
|
T16288 |
Neuropathiazol
|
880090-88-0
|
98%
|
|
Neuropathiazol causes neuronal differentiation of adult hippocampal neural progenitor cells.
|
T17028 |
Tefinostat
|
914382-60-8
|
98%
|
|
Tefinostat is a monocyte/macrophage-targeted pan HDAC inhibitor. That is cleaved into active acid CHR-2847 by the intracellular esterase human carboxylesterase-1...
|
TN4288 |
Isoferulic acid
|
25522-33-2
|
98%
|
|
Isoferulic acid is an effective natural antioxidant in both lipid and aqueous media, it may be a new promising anti-glycation agent for the prevention of diabeti...
|
T11329 |
FT895
|
2225728-57-2
|
98%
|
|
FT895 is a selective and potent selective HDAC11 inhibitor with an IC50 of 3 nM.
|
T14936 |
Ivaltinostat
|
936221-33-9
|
98%
|
|
CG-200745 is a potent inhibitor of HDAC. CG200745 induces apoptosis and also inhibits the deacetylation of histone H3 and tubulin.
|
T11544 |
HDACs/mTOR Inhibitor 1
|
2271413-06-8
|
98%
|
|
HDACs/mTOR Inhibitor 1 is a dual HDACs and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies (IC50s: 0.19 nM, 1.8 nM, 1...
|
T15605 |
JAK/HDAC-IN-1
|
2284621-75-4
|
98%
|
|
JAK/HDAC-IN-1 is an effective JAK2/HDAC dual inhibitor (IC50s: 4 and 2 nM for JAK2 and HDAC). It also shows antiproliferative and proapoptotic activities in seve...
|
T10864 |
Corin
|
1808113-09-8
|
98%
|
|
Corin is an irreversible inhibitor of HDAC1(IC50 = 147 nM) and LSD1(Ki = 110 nM).
|
T2S0606 |
Bakkenolide A
|
19906-72-0
|
98%
|
|
Bakkenolide A has antifeedant and growth inhibitory effects on neonate variegated cutworms, it inhibits leukemia by regulation of HDAC3 and PI3K/Akt-related sign...
|
T11543 |
HDAC-IN-5
|
1314890-51-1
|
98%
|
|
HDAC-IN-5 is a histone deacetylase (HDAC) inhibitor.
|
T11706 |
JAK1-IN-7
|
2241039-81-4
|
98%
|
|
JAK1-IN-7 is a Janus-associated kinase 1 (JAK1) inhibitor, has an anti-inflammatory effect.
|
T11542 |
HDAC-IN-4
|
1252003-13-6
|
98%
|
|
HDAC-IN-4 is a selective HDAC6 and HDAC10 inhibitor (pIC50s: 7.2 and 6.8 in BRET assay) with antitumoral activity.
|
T6637 |
Resminostat
|
864814-88-0
|
98%
|
|
Resminostat is an orally bioavailable inhibitor of histone deacetylases (HDACs) with potential antineoplastic activity.
|
T14305 |
Apicidin
|
183506-66-3
|
98%
|
|
Apicidin (OSI 2040) is a fungal metabolite, acts as a histone deacetylase (HDAC) inhibitor. It has antiparasitic activity and a broad spectrum antiproliferative ...
|
T14947 |
CHDI-390576
|
1629729-98-1
|
98%
|
|
CHDI-390576 is a CNS penetrant class IIa HDAC inhibitor (IC50s: 54 nM, 60 nM, 31 nM, 50 nM for class IIa HDAC4, HDAC5, HDAC7, HDAC9). It shows >500-fold selectiv...
|
T21715 |
BRD6688
|
1404562-17-9
|
98%
|
|
BRD6688 is a selective HDAC2 inhibitor that acts by enhancing the learning and memory processes
|
T25175 |
BRD 9757
|
1423058-85-8
|
98%
|
|
BRD 9757 is a selective inhibitor of HDAC6 (IC50 = 30 nM).
|