T60919 |
SARS-CoV-2-IN-13
|
56961-10-5
|
98%
|
|
SARS-CoV-2-IN-13 is a niclosamide analogue. SARS-CoV-2-IN-13 (compound 5) potently inhibits SARS-CoV-2 (IC50=0.057 μM). SARS-CoV-2-IN-13 shows higher stability i...
|
T6200 |
Ledipasvir
|
1256388-51-8
|
98%
|
|
Ledipasvir is a Hepatitis C Virus NS5A Inhibitor. The mechanism of action of ledipasvir is as a P-Glycoprotein Inhibitor, and Breast Cancer Resistance Protein In...
|
T5539 |
GS-443902
|
1355149-45-9
|
98%
|
|
GS-441524 was shown to be a safe and effective treatment for feline infectious peritonitis (FIP). The optimum dosage was found to be 4.0 mg/kg SC q24h for at lea...
|
T9293 |
SSAA09E3
|
52869-18-8
|
98%
|
|
SSAA09E3 is a novel inhibitor of SARS-CoV replication, acting by preventing fusion of the viral membrane with the host cellular membrane.
|
T0211 |
Azelastine
|
58581-89-8
|
98%
|
|
Azelastine is a phthalazine derivative, and is an histamine antagonist and mast cell stabilizer.
|
T9715 |
Aplidine
|
137219-37-5
|
98%
|
|
Aplidine possesses antiviral activity against SARS-CoV-2(IC90 = 0.88 nM). Aplidine is a potent anti-cancer agent by targeting eukaryotic translation elongation f...
|
T21727 |
Ivermectin B1a
|
71827-03-7
|
98%
|
|
Ivermectin B1a is the major (80%) component of commercially available ivermectin and a derivative of Avermectin B1a.
|
T9618 |
HeE1-2Tyr
|
2245195-67-7
|
98%
|
|
HeE1-2Tyr, a pyridobenzothiazole compound, is a flavivirus RNA dependent RNA polymerases (RdRp) inhibitor. It significantly inhibits West Nile, Dengue and SARS-C...
|
T9614 |
MERS-CoV-IN-1
|
2245697-92-9
|
98%
|
|
MERS-CoV-IN-1 exhibits excellent inhibitory activity against coronavirus.It is useful as a pharmaceutical composition for preventing coronavirus-induced diseases...
|
T9606 |
TC-067533
|
1093070-10-0
|
98%
|
|
TC-067533 is a Papain-like protease inhibitor with an IC50 of 8.7 μM.
|
T9617 |
RdRP-IN-2
|
|
98%
|
|
RdRP-IN-2 is a RNA dependent RNA polymerase (RdRp) inhibitor. It significantly inhibits SARS-CoV-2 RdRp with an IC50 of 41.2 µM.It also inhibits Feline coronavir...
|
T60085 |
MM3122
|
2574390-27-3
|
98%
|
|
MM3122 is a selective type II transmembrane serine protease (TMPRSS2) inhibitor, IC50 = 0.34 nM. MM3122 effectively blocks TMPRSS2, thereby inhibiting the entry ...
|
T40276 |
GS-621763
|
2647442-13-3
|
98%
|
|
GS-621763, a prodrug of GS-441524, exhibits antiviral activity against SARS-CoV-2 pathogenesis.
|
T60095 |
CCF0058981
|
2708934-53-4
|
98%
|
|
CCF0058981 (CCF981), 3-chlorophenyl analogue, is a noncovalent SARS-CoV-2 3CL pro (SC2) inhibitor with an IC 50 of 68 nM. CCF0058981 inhibits SC1 (SARS-CoV-1 3CL...
|
T9672 |
GRL-0496
|
1087243-14-8
|
98%
|
|
GRL-0496 is a potent inhibitor with an enzyme inhibitory activity against SARS-CoV 3CLpro with an IC50 of 30 nM and antiviral potency with an EC50 value of 6.9 μ...
|
T60045 |
NK01-63
|
T60045
|
98%
|
|
Coronastat is a potent inhibitor of the SARS-CoV-2 3CL protease.
|
T6670 |
Silymarin
|
65666-07-1
|
|
|
Silymarin (Silybin B) is a polyphenolic flavonoid that extracts from the milk thistle or seeds of Silybum marianum. It is used in the prevention and treatment of...
|
T20033 |
Direct Violet 1
|
2586-60-9
|
|
|
Direct Violet 1 is an agent of dye.
|
T9351 |
Nirmatrelvir
|
2628280-40-8
|
|
|
PF-07321332 is a potent and orally active inhibitor of SARS-CoV 3C-like protease (3CLPRO) .
|
T7903 |
Saquinavir
|
127779-20-8
|
100%
|
|
Saquinavir is a potent HIV protease inhibitor, is an antiretroviral drug used together with other medications to treat or prevent HIV/AIDS.
|