TN4923 |
Rubicordifolin
|
849699-55-4
|
98%
|
|
Rubicordifolin exhibits potent cytotoxic and antitumor activities.
|
TN4107 |
Ganoderic acid X
|
86377-53-9
|
98%
|
|
Ganoderic acid X is a potential Mdm2 inhibitor(K(i) = 16nM). It is a potential anticancer drug, inhibits topoisomerases and induces apoptosis of cancer cells.
|
TQ0134 |
Podocarpusflavone A
|
22136-74-9
|
98%
|
|
Podocarpusflavone A is a DNA topoisomerase I inhibitor. It has moderated anti-proliferative activity induce cell apoptosis in MCF-7.
|
T14945 |
CH-0793076
|
534605-78-2
|
98%
|
|
CH-0793076, a hexacyclic camptothecin analog, is an active drug and major metabolite of TP300. CH-0793076 is efficacious against cells expressing BCRP (breast ca...
|
TN1169 |
1,4-Dihydroxy-2-carbomethoxy-3-prenylnaphthalene-1-O-β-D-glucopyranoside
|
1415729-43-9
|
98%
|
|
1,4-Dihydroxy-2-carbomethoxy-3-prenylnaphthalene-1-O-beta-glucopyranoside may have DNA topoisomerases I and II inhibitory activity and cytotoxicity.
|
T15586 |
Intoplicine
|
125974-72-3
|
98%
|
|
Intoplicine is an inhibitor of DNA topoisomerase I and II.
|
TN4422 |
Lauterine
|
28200-65-9
|
98%
|
|
Lauterine is a DNA topoisomerase inhibitor.
|
TN4283 |
Isodiospyrin
|
20175-84-2
|
98%
|
|
Isodiospyrin is a novel human DNA topoisomerase I inhibitor, it exhibits cytotoxic activity to tumor cell lines. Isodiospyrin has antibacterial activity, the min...
|
TN2953 |
3-Hydroxysarpagine
|
857297-90-6
|
98%
|
|
Standard reference
|
TN5133 |
3',5,5',7-Tetrahydroxy-4',6-dimethoxyflavone
|
125537-92-0
|
98%
|
|
5,7,3',5'-tetrahydroxy-6,4'-dimethoxyflavone exhibits anti-HIV-1 activity in the anti-syncytium assay using (∆Tat/rev)MC99 virus and 1A2 cell line system, it sho...
|
T15054 |
Daun02
|
290304-24-4
|
98%
|
|
Daun02 is the topoisomerase inhibitor Daunorubicin prodrug.
|
T14953 |
Chloroquinoxaline sulfonamide
|
97919-22-7
|
98%
|
|
Chloroquinoxaline sulfonamide is a topoisomerase II alpha/beta poison. It is used to control coccidiosis in poultry, rabbit, sheep, and cattle.
|
T16286 |
Nelonemdaz
|
640290-67-1
|
98%
|
|
Neu2000 is an uncompetitive antagonist of N-methyl-D-aspartate (NMDA) receptor.
|
T14703 |
Karenitecin
|
203923-89-1
|
98%
|
|
Karenitecin (Cositecan) is an inhibitor of topoisomerase I. It has potent anti-cancer activity.
|
TN5190 |
Tryprostatin A
|
171864-80-5
|
98%
|
|
Tryprostatin A is an inhibitor of breast cancer resistance protein. Tryprostatin A and tryprostatin B are indole alkaloid-based fungal products that inhibit mamm...
|
TN1889 |
Lupalbigenin
|
76754-24-0
|
98%
|
|
Lupalbigenin sensitizes detachment-induced cell death in human lung cancer cell through down-regulation of pro-survival proteins.
|
TN4173 |
Guajadial C
|
1529775-02-7
|
98%
|
|
Guajadial C acts as a Top1 catalytic inhibitor and can delay Top1 poison-mediated DNA damage. It shows cytotoxicity against five human cancer cell lines.
|
TN2464 |
Eleutherin
|
478-36-4
|
98%
|
|
Eleutherin is a natural product from Eleutherine americana
|
T15200 |
Edotecarin
|
174402-32-5
|
98%
|
|
Edotecarin is a potent topoisomerase I inhibitor. It can decrease single-strand DNA cleavage (IC50: 50 nM).
|
TN4172 |
Guajadial B
|
1414455-03-0
|
98%
|
|
Guajadial B acts as a Top1 catalytic inhibitor and delays Top1 poison-mediated DNA damage. Guajadial B shows cytotoxicities against five human cancer cell lines,...
|