Search Result

Search Results for "bcl"

Targets

Libraries

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Compounds

Cat No.	Product Name
T38622	Bcl-xL antagonist 2		BCL
	Bcl-xL antagonist 2 is an effective and selective antagonist of Bcl-xL with an IC50 of 91 nM and a Ki of 65 nM. Bcl-xL a...		BCL
T6275	Obatoclax Mesylate	Obatoclax , GX15-070	BCL , Autophagy , Parasite
	Obatoclax is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c r...		BCL , Autophagy , Parasite
T17018	TCPOBOP		BCL
	TCPOBOP is a constitutive androstane receptor agonist that induces robust hepatocyte proliferation and hepatomegaly. TCP...		BCL
T39910	Desmorpholinyl Navitoclax-NH-Me	Desmorpholinyl ABT-263-NH-Me	BCL
	Desmorpholinyl Navitoclax-NH-Me is a Bcl-xL inhibitor. Desmorpholinyl Navitoclax-NH-Me and a CRBN ligand for the E3 ubiq...		BCL
T40412L	BAD (103-127) (human) acetate	BAD (103-127) (human) acetate (331762-68-6 Free base)	Others
	BAD (103-107) (human) is a 25-mer Bad polypeptide from the BAD BH3 domain that antagonizes the effects of Bcl-xl.		Others
T7027	EURYCOMANONE	Pasakbumin A	Others
	Eurycomanone is cytotoxic on HepG2 cells by inducing apoptosis through the up-regulation of p53 and Bax, and down-regula...		Others
T6S1653	Albiflorin	Alibiflorin	Reactive Oxygen Species
	1. Albiflorin has anticonvulsant effect for pain relief. 2. Albiflorin and paeoniflorin has neuroprotective action again...		Reactive Oxygen Species
T6S1418	Praeruptorin C		Antioxidant , Calcium Channel
	1. Praeruptorin C has been widely used as an antioxidant and a calcium antagonist to treat diseases. 2. Praeruptorin C p...		Antioxidant , Calcium Channel
T5408	BI-3802		BCL
	BI-3802 is a highly potent BCL6 degrader and inhibits the Bric-à-brac (BTB) domain of BCL6 with an IC50 value of ≤3 nM. ...		BCL
T6778	BDA-366		BCL
	BDA-366 is a potent Bcl2 antagonist, binding Bcl2-BH4 domain with high affinity and selectivity (Ki = 3.3 nM). BDA-366 i...		BCL
T1979	AVN-944	VX-944	Dehydrogenase
	AVN-944(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2.		Dehydrogenase
T16028	IMB-XH1	Mcl1-IN-2	BCL , Antibacterial
	Mcl1-IN-2 is a myeloid cell factor 1 (Mcl-1) inhibitor.		BCL , Antibacterial
T39961	Bcl-2-IN-2
	Bcl-2-IN-2 is a potent and selective Bcl-2 inhibitor with an IC 50 of 0.034 nM and also inhibits Bcl-xL with an IC 50 of...
T11968	MCL-1/BCL-2-IN-1		BCL
	MCL-1/BCL-2-IN-2 (Compound Nap-1) is a potent and selective dual inhibitor of Mcl-1 and Bcl-2 with IC 50 s of 4.45 and 3...		BCL
T6314	(R)-(-)-Gossypol	AT101 , R-(-)-gossypol acetic acid	BCL , Autophagy
	AT101, the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 μM, 0.48 μM and ...		BCL , Autophagy
T38810	BM-1197
	BM-1197 is a potent and selective inhibitor of dual Bcl-2/Bcl-xL , with IC 50 s of 3.5 nM and 5.2 nM for Bcl-2 and Bcl-x...
T40230	Mcl-1 inhibitor 6
	Mcl-1 inhibitor 6 is an orally active, selective myeloid cell leukemia 1 (Mcl-1) protein inhibitor with a K d of 0.23 nM...
T39909	XZ739
	XZ739, a Cereblon -dependent PROTAC BCL-XL ( Bcl-2 family member) degrader with a DC 50 value of 2.5 nM in MOLT-4 cells ...
T40135	PZ703b
	PZ703b is a novel BCL-XL PROTAC degrader with enhanced BCL-2 inhibition.
T39135	S65487 hydrochloride	VOB560 hydrochloride
	S65487 (VOB560) hydrochloride is a potent and selective Bcl-2 inhibitor. S65487 hydrochloride is also active on BCL-2 mu...