Akt

Protein kinase B (PKB), also known as Akt, is a serine/threonine-specific protein kinase that plays a key role in multiple cellular processes such as glucose metabolism, apoptosis, cell proliferation, transcription, and cell migration.

Cat. No.	Product name	CAS No.	Purity
TN3806	Dehydroglyasperin C	199331-35-6	98%
TN3806	Dehydroglyasperin C is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C possesses potent antioxidant, cancer chemop...
TN1269	3β-Methoxy-2,3-dihydrowithaferin A	73365-94-3	98%
TN1269	3beta-Methoxy-2,3-dihydrowithaferin A has cytoprotective activity, it protects normal cells against stress.
TN2328	Zeylenone	193410-84-3	98%
TN2328	Zeylenone has good antitumor efficacy, it inhibits proliferation and induces apoptosis in cervical carcinoma cells via PI3K/AKT/mTOR and MAPK/ERK pathways. Zeyle...
TN1376	α-Solanine	20562-02-1	98%
TN1376	Alpha-Solanine alters antioxidative enzyme activities and MDA and PCO concentrations and GST activity in fat body and midgut.
TN1462	Cajanin	32884-36-9	98%
TN1462	Cajanin has potential hypolipidemic effects,possibly via up-regulating the ABCA1 protein expression,subsequently resulting in increased macrophage cholesterol ef...
TN3726	Cudraflavone B	19275-49-1	98%
TN3726	Cudraflavone B has anti-proliferative activity, mouse brain monoamine oxidase (MAO) inhibitory effects, apoptotic actions in human gastric carcinoma cells and mo...
TN3655	Cimiside E	154822-57-8	98%
TN3655	Cimiside E has anti-inflammatory activity, it selectively inhibits TNF-α-induced expression of VCAM-1 at least by upregulation of PPAR-γ, and signals for ERK1/2,...
TN4675	Nortrachelogenin	34444-37-6	98%
TN4675	Nortrachelogenin is a novel agent for prostate cancer therapy with ability to inhibit Akt membrane localization and activity as well as the activation of growth ...
T16155	MSN-125	1592908-16-1	98%
T16155	MSN-125 effectively inhibits Bax/Bak-mediated apoptosis in HCT-116, BMK Cells, and primary cortical neurons protect primary neurons against glutamate excitotoxic...
TN1889	Lupalbigenin	76754-24-0	98%
TN1889	Lupalbigenin sensitizes detachment-induced cell death in human lung cancer cell through down-regulation of pro-survival proteins.
T12397	KP-23172	331253-86-2	98%
T12397	KP-23172 is a inhibitor of PI3-K/Akt pathway.
T15469	Hematein	475-25-2	98%
T15469	Hematein inhibits Akt/PKB Ser129 phosphorylation, the Wnt/TCF pathway, and increases apoptosis in lung cancer cells. Hematein is an oxidation product of hematoxy...
TN4356	Jolkinolide A	37905-07-0	98%
TN4356	Jolkinolide A has anti-tumor activity. It inhibited VEGF expression in A549 cells through the inhibition of the Akt-STAT3-mTOR signaling pathway, and directly in...
T10274	AKT-IN-2	1295514-91-8	98%
T10274	AKT-IN-2 is a selective, and orally bioavailable AKT inhibitor (IC50: 5 nM for AKT1).
TN4932	Sageone	142546-15-4	98%
TN4932	Sageone represents a promising anticancer agent against gastric cancer that warrants further study, it synergizes with cisplatin cytotoxicity in SNU-1 human gast...
T10276	AKT Kinase Inhibitor	842148-40-7	98%
T10276	AKT Kinase Inhibitor is an inhibitor of Akt kinase with anti-tumor activity.
TN3525	Boehmenan	57296-22-7	98%
TN3525	(±)-Boehmenan shows potent protein-tyrosine phosphatase 1B (PTP1B) inhibitory activity in vitro with the IC(50) values of 43.5 uM, it inhibits PTP1B activity in ...
TN4683	Nyasol	96895-25-9	98%
TN4683	Nyasol may have potential to be developed as medicines for the treatment of allergies by inhibiting the activation of mast cells. Nyasol shows anti-inflammatory ...
T2S0606	Bakkenolide A	19906-72-0	98%
T2S0606	Bakkenolide A has antifeedant and growth inhibitory effects on neonate variegated cutworms, it inhibits leukemia by regulation of HDAC3 and PI3K/Akt-related sign...
TN3753	Dalbergioidin	30368-42-4	98%
TN3753	Dalbergioidin exhibits tyrosinase inhibitory activity with an IC50 of 20 mM. It shows a melanin biosynthesis inhibition zone in the culture plate of Streptomyces...