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GPR

G-protein coupled receptors (GPRs) are a family of seven-transmembrane receptors, which play an important role in the response to peptide hormones, neurotransmitters, and free fatty acids.

Cat. No.	Product name	CAS No.	Purity
TQ0241	TUG-770	1402601-82-4	98%
TQ0241	TUG-770 is a highly potent agonist of free fatty acid receptor 1 (FFA1/GPR40, EC50: 6 nM for hFFA1).
T10507	GPR40 Agonist 2	1147729-48-3	98%
T10507	GPR40 Agonist 2 is a GPR40 agonist. It can be used in the research of diabetes.
T11044	Dihydromunduletone	674786-20-0	98%
T11044	Dihydromunduletone (DHM) is an adhesion G protein-coupled receptor (aGPCR) antagonist that acts as a chemical probe for the inhibition of GPR56 and GPR114/ADGRG5...
T4689	Palosuran hydrochloride 540769-28-6(free base）	T4689	98%
T4689	Palosuran hydrochloride 540769-28-6(free base)(ACT-058362 hydrochloride) is a new potent and specific antagonist of the human UT receptor with an IC50 of 3.6±0.2...
T15283	Firuglipel	1371591-51-3	98%
T15283	Firuglipel is an orally available and selective agonist of GPR119.
T14200	AM-1638	1142214-62-7	98%
T14200	AM-1638 is a full agonist of GPR40/FFA1 (EC50: 0.16 μM).
T14202	AM-4668	1011531-27-3	98%
T14202	AM-4668 is a type 2 diabetes GPR40 agonist. For GPR40, in A9 cells (GPR40 IP3 assay) and CHO cells (GPR40 aequorin assay), the EC50s are 3.6 nM and 36 nM, respec...
T37264	15(R)-15-methyl Prostaglandin D2	210978-26-0	98%
T37264	15(R)-15-methyl Prostaglandin D2 (15(R)15methyl PGD2) is a synthetic analogue of PGD2 and a selective and potent CRTH2/DP2 receptor agonist that modulates eosino...
T62858	HGPR91 antagonist 3	1314796-31-0	98%
T62858	hGPR91 antagonist 3 is an orally active, potent, and selective hGPR91 antagonist. hGPR91 antagonist 3 is used to study hypertension, autoimmune diseases, and ret...
T15448	GW-1100	306974-70-9	98%
T15448	GW-1100 is a selective antagonist of GPR40 (pIC50: 6.9). GW1100 also plays the role of a GPR40 inverse agonist.
T2351L	TAK-875 Hemihydrate	1374598-80-7	98%
T2351L	TAK-875 Hemihydrate (Fasiglifam) is a selective GPR40 agonist with EC50 of 14 nM, 400-fold more potent than oleic acid.
T11452	GPR120 Agonist 1	1628448-77-0	98%
T11452	GPR120 Agonist 1 is a selective GPR120 agonist. In GPR120 transfected HEK293 cells, GPR120 Agonist 1 displays good EC50 of 42 nM and 77 nM for human and mouse GP...
T11460	GPR4 antagonist 1	1197879-16-5	98%
T11460	GPR4 antagonist 1 is a GPR4 antagonist (IC50: 189 nM).
TP2166	Urotensin II, mouse TFA (9047-55-6 free base)	TP2166	98%
TP2166	Urotensin II, mouse TFA is an endogenous ligand for the orphan GPR14 or SENR. It is a potent vasoconstrictor.
T12778L	RTI-13951-33	2244884-08-8	98%
T12778L	RTI-13951-33 is an effective and brain-penetrant GPR88 agonist (EC50: 25 nM, in GPR88 cAMP functional assay).
TQ0051	MK-7246	1218918-62-7	98%
TQ0051	MK-7246 is a potent and specific CRTH2 antagonist (Ki: 2.5 nM).
T11462	GPR84 antagonist 8	1445846-30-9	98%
T11462	GPR84 antagonist 8 is a selective GPR84 antagonist.
T21623	AS1269574	330981-72-1	99.98%
T21623	AS1269574 is a potent, orally available GPR119 agonist. AS1269574(AS 1269574) has the potential for the research of type 2 diabetes.
T2088	APD668	832714-46-2	99.97%
T2088	APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119, respectively.
T2396	Ramatroban	116649-85-5	99.96%
T2396	Ramatroban (BAY u3405) (BAY u3405) is a thromboxane A(2) (TxA(2)) antagonist marketed for allergic rhinitis. It has been used in trials studying the treatment of...