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Results for "ang" in TargetMol Product Catalog
  • Inhibitor Products
    382
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Angiotensin II human
T70404474-91-3
Angiotensin II human (Ang II) is a biologically active peptide, a vasoconstrictor. Angiotensin II interacts with AT1R and AT2R to regulate blood pressure, stimulate sympathetic nerves, and increase aldosterone biosynthesis and renal activity in humans.
  • $37
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Angiotensin II human acetate
T856068521-88-0
Angiotensin II human acetate (DRVYIHPF acetate) is a vasoconstrictor that mainly acts on the AT1 receptor.
  • $33
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Angiotensin (1-7)
T733951833-78-4
Angiotensin (1-7) (ASP-ARG-VAL-TYR-ILE-HIS-PRO) is a synthetic heptapeptide identical to endogenous angiotensin-(1-7) , inhibits purified canine ACE activity (IC50=0.65 μM) with vasodilator and antiproliferative activities.
  • $33
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ANG1005
T780341075214-55-9
ANG1005 is a brain-penetrating peptide-agent conjugate comprising a taxane derivative that features three paclitaxel molecules covalently bonded to Angiopep-2. This design facilitates crossing of the blood-brain and blood-cerebrospinal barriers, with subsequent penetration of malignant cells through the low-density lipoprotein receptor-related protein (LRP1) transport system [1] [2] [3].
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[Sar1, Ile8]-Angiotensin II 3TFA
T7575L
[Sar1, Ile8]-Angiotensin II 3TFA ([Sar1, Ile8]-Angiotensin II 3TFA (37827-06-8(free base))) is a peptide that has multiple effects on vascular smooth muscle.
  • $48
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Angiotensinogen (1-14), human acetate
TP1842L
Angiotensinogen (1-14), human acetate is a fragment of angiotensinogen which is a passive substrate of the renin-angiotensin system.
  • $86
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Angiotensin II 5-valine TFA
TP1017L
Angiotensin II 5-valine TFA is an agonist of angiotensin receptor.
  • $53
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Acetyl Angiotensinogen (1-14), porcine Acetate
T21582L
Acetyl Angiotensinogen (1-14), porcine Acetate is a peptide with the sequence AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH. The protein encoded by the Angiotensinogen gene is known as pre-angiotensinogen or angiotensinogen precursor.
  • $53
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Angiotensin I/II (1-5)
TP152858442-64-1
Angiotensin I/II (1-5) is a peptide (ASP-ARG-VAL-TYR-ILE) that contains the amino acids 1-5 and is converted from Angiotensin I/II.
  • $50
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[Sar1, Ile8]-Angiotensin II acetate
T7575L1
[Sar1, Ile8]-Angiotensin II acetate activates both the NADPH and NADH oxidases, and stimulates superoxide anion formation in vascular smooth muscle cells. [Sar1, Ile8]-Angiotensin II acetate has multiple effects on vascular smooth muscle, including contra
  • $37
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Angiotensin amide acetate
TP2446L
Angiotensin amide acetate is a derivative of Angiotensin amide, an octapeptide amide that increases blood pressure through vasoconstriction.
  • $148
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Angiotensin 1/2 (1-9) TFA
T7663L
Angiotensin 1/2 (1-9)TFA is containing the amino acids 1-9 that are converted from Angiotensin I/II peptide.
  • $50
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Angiotensin 1/2 (5-7) acetate
T22574L
Angiotensin 1/2 (5-7) acetate is a peptide with the sequence H2N-Ile-His-Pro-OH. Angiotensin is an oligopeptide and is a hormone and a powerful dipsogen. It is derived from the precursor molecule angiotensinogen, a serum globulin produced in the liver. It
  • $37
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Angiotensin I/II (1-6)
TP157947896-63-9
Angiotensin I/II (1-6) is a peptide (ASP-ARG-VAL-TYR-ILE-HIS) that contains the amino acids 1-6 and is converted from Angiotensin I/II peptide.
  • $50
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Angiotensin-converting enzyme
T761699015-82-1
Angiotensin-converting enzyme (ACE), a dicarboxypeptidase, converts inactive Angiotensin I (Ang I) to its active form, Angiotensin II (Ang II), and degrades active bradykinin (BK), functioning as a potent vasoconstrictor frequently utilized in biochemical studies [1].
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7-10 days
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Nangibotide
T817072014384-91-7
Nangibotide, a TREM-1 receptor inhibitor, modulates the innate immune response and has demonstrated the potential to reduce systemic and localized inflammatory reactions in rodent models of myocardial ischemia-reperfusion [1].
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Angiotensin II (5-8), human
TP152234233-50-6
Angiotensin II (5-8) is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin II
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[Sar1, Ile8]-Angiotensin II
T757537827-06-8
[Sar1, Ile8]-Angiotensin II(3TFA) is a peptide that has multiple effects on vascular smooth muscle.
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Manganese tripeptide-1
T81869611182-15-1
Manganese Tripeptide-1 is a bioactive peptide recognized for its anti-wrinkle properties and ability to diminish skin hyperpigmentation. It has been documented as an ingredient in cosmetics [1].
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Angiotensin amide
TP244653-73-6
Angiotensin amide, an octapeptide amide, can be used to increase blood pressure by vasoconstriction.
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Gersizangitide acetate
T40076L
Gersizangitide acetate is an inhibitor of angiogenesis.
  • $144
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Angiotensin II (1-4), human
TP160952580-29-7
Angiotensin II is a potent direct vasoconstrictor, causing arteries and veins to constrict, so leading to an increase in blood pressure. Angiotensin also potentiates the release of norepinephrine by a direct action on postganglionic sympathetic fibers.
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Angiotensin 1/2 (1-9)
T766334273-12-6
Angiotensin 1/2 (1-9) is containing the amino acids 1-9 that are converted from Angiotensin I/II peptide.
  • $53
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[Val4] Angiotensin III
T83483100900-28-5
[Val4] Angiotensin III is an angiotensin III peptide variant and a potent full agonist for Gαq and βarr2 signaling pathways, exhibiting pEC50 values of 8.31 and 8.44, respectively [1].
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Angiopep-Bim BH3 hydrochloride
T83114
Angiopep-Bim BH3 hydrochloride, a peptode that penetrates the blood-brain barrier (BBB), may serve as a tool to study the permeability of central nervous system (CNS) therapeutics [1].
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Nangibotide TFA
T78019
Nangibotide TFA, a TREM-1 receptor inhibitor, modulates the innate immune response and attenuates both systemic and localized inflammatory reactions in rodent models of myocardial ischemia-reperfusion [1].
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[Tyr(P)4] Angiotensin II
T38697129785-85-9
[Tyr(P)4] Angiotensin II is a peptide that exerts a multitude of effects on vascular smooth muscle. These effects include the contraction of normal arteries, as well as the induction of hypertrophy or hyperplasia in cultured cells or diseased vessels.
  • $1,520
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(Sar1)-Angiotensin II
T3583451833-69-3
The substitution with Sar at position 1 of angiotensin II resulted in a partial agonistic activity.
  • $291
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Guangxitoxin 1E
TP15311233152-82-3
Guangxitoxin 1E acts as a gating modifier since it shifts the voltage-dependence of Kv2.1 K+ currents towards depolarized potentials.
  • $889
35 days
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Angiotensin II 5-valine
TP101758-49-1
ngiotensin II 5-valine is an angiotensin II analog which is an agonist at angiotensin receptors.
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Tuna AI acetate
T24906L
Tuna AI acetate is an inhibitor of angiotensin-converting enzyme (ACE) in non-competitive manner derived from tuna muscle.
  • $195
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Angiotensin III, human, mouse
T757713602-53-4
Angiotensin III, human, mouse (Angiotensin III, human, mouse(3TFA))(3TFA) is an endogenous angiotensin II receptor (AT2R) agonist(IC50s of 0.648 nM).
  • $48
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Angiotensin (1-7) (acetate)
T374952855063-75-9
Angiotensin 1-7 (Ang-(1-7)) acetate, an endogenous heptapeptide from the renin-angiotensin system (RAS), exhibits cardioprotective effects through its anti-inflammatory and anti-fibrotic activities in cardiac cells. It effectively inhibits purified canine ACE activity (IC 50 =0.65 μM) and serves as a local synergistic modulator of kinin-induced vasodilation by hindering ACE and facilitating nitric oxide release. Additionally, this compound prevents Ang II-induced proliferation and hypertrophy in smooth muscle cells, alongside demonstrating antiangiogenic and growth-inhibitory effects on the endothelium [1] [2] [3].
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Angstrom6
T26629220334-14-5
Angstrom6 (A-6 peptide) is an 8 amino acid peptide derived from single chain urokinase fibrinogen activator (scuPA) that interferes with the uPA/uPAR cascade and abrogates the downstream effects.Angstrom6 has antitumor activity and inhibits tumor cell migration, invasion, and metastasis by binding to CD44 and modulating CD44-mediated cell signaling.
  • $49
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Angiotensin III, human, mouse TFA
T75975
Angiotensin III, human, mouse (TFA) is an angiotensin.
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Angiotensin II human TFA
T741422761969-44-0
Angiotensin II human TFA, a potent vasoconstrictor within the renin/angiotensin system, plays a pivotal role in human blood pressure regulation primarily through interactions with the G-protein-coupled receptors Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). It not only prompts sympathetic nervous stimulation, aldosterone biosynthesis, and renal effects but also fosters growth in vascular smooth muscle cells and boosts collagen type I and III synthesis in fibroblasts. This action results in the thickening of the vascular wall and myocardium, alongside fibrosis. Additionally, Angiotensin II human TFA triggers apoptosis and encourages capillary formation from endothelial cells through the LOX-1 dependent redox-sensitive pathway [1] [2] [3] [4].
  • $38
5 days
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(Sar1,Ile4,8)-Angiotensin II
T76634185461-45-4
(Sar1,Ile4,8)-Angiotensin II is a functionally selective agonist for the angiotensin II type 1 receptor (AT1R), enhancing insulin-stimulated signaling of the insulin receptor (IR) and glycogen synthesis. It boosts the insulin-induced phosphorylation of Akt and GSK3α/β [1].
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Angiotensin II (1-4), human TFA
TP1661
Angiotensin II is a potent direct vasoconstrictor, causing arteries and veins to constrict, so leading to an increase in blood pressure.
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Angiotensin pentapeptide
TP237052530-60-6
Angiotensin pentapeptide is a peptide.
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Angiogenin (108-122)
TP1362112173-49-6
Angiogenin (108-122) is an angiogenin peptide. Angiogenin (108-122) acts as a therapeutic agent for the prophylaxis and/or treatment of cancer, an infectious disease, a fibrotic disease, an inflammatory disease, a neurodegenerative disease, an autoimmune
  • $103
7-10 days
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Angiotensinogen (1-14), human
TP1842104180-23-6
Angiotensinogen is a serum globulin formed by the liver that is cleaved by renin to form angiotensin I. Angiotensinogen is also called angiotensin precursor.
  • $72
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[Sar1, Ile8]-Angiotensin II TFA
TP1224
[Sar1, Ile8]-Angiotensin II (TFA) is a peptide compound that exerts various effects on vascular smooth muscle. These effects include the contraction of normal arteries as well as the hypertrophy or hyperplasia of cultured cells or diseased vessels.
  • $90
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Angiotensin I, asn(1)-val(5)-gly(9)-
TP244795211-04-4
Angiotensin I, asn(1)-val(5)-gly(9)- is isolated from the plasma of American eel, Anquilla rostrata.
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Angiopeptin
T25087113294-82-9
Angiopeptin is a synthetic octapeptide analog of somatostatin; suppresses accelerated transplant atherosclerosis in rabbit heart arteries.
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Gersizangitide
T400762417491-82-6
Gersizangitide is an angiogenesis inhibitor.
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Angiotensin III
T1032212687-51-3
Angiotensin III is an agonist of angiotensin 1 (AT1) and AT2 receptor.
  • $1,520
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Angiopeptin TFA
T760422478421-60-0
Angiopeptin TFA, a cyclic octapeptide analogue of somatostatin, acts as a partial agonist at sst 2/sst 5 receptors, exhibiting IC50 values of 0.26 nM and 6.92 nM, respectively. This compound effectively inhibits the release of growth hormone and the production of insulin-like growth factor-1 (IGF-1). Additionally, it either inhibits adenylate cyclase activity or promotes extracellular acidification. Notably, Angiopeptin TFA shows promise for use in coronary atherosclerosis research [1] [2].
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Angiotensinogen (1-14), human TFA
TP2168
Angiotensinogen (1-14), human TFA is a fragment of the renin substrate angiotensinogen. Angiotensinogen is a precursor for all angiotensin peptides.
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Angiotensin II (3-8), human
T582412676-15-2
Angiotensin II (3-8), human is a less effective agonist at the angiotensin AT1 receptor.
  • $84
7-10 days
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Angiopep-2 hydrochloride
T78016
Angiopep-2 hydrochloride is a brain-targeting peptide vector. Conjugating anticancer agents to Angiopep-2 may enhance their therapeutic effect against brain cancer [1].
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