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Search Results for " angiogenesis "

Libraries

Angiogenesis related Compound Library Tyrosine Kinase Inhibitor Library Flavonoid Natural Product Library HIF-1 Signaling Pathway Compound Library

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Compounds

Cat No.	Product Name
T74627	Angiogenesis inhibitor 3
	Angiogenesis inhibitor 3 (compound 8) is a potent angiogenesis inhibitor. Angiogenesis inhibitor 3 inhibits the prolifer...
T74217	Angiogenesis agent 1
	Angiogenesis agent 1 (compound C-31) is a salidroside-derivated glycoside analogue. Angiogenesis agent 1 is an activator...
T71722	Angiogenesis inhibitor BT2
	Angiogenesis inhibitor BT2 is a novel inhibitor of angiogenesis and vascular permeability, inhibiting ERK phosphorylatio...
T2427	EHop-016	EHop 016	Ras , Rho
	EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally eff...		Ras , Rho
T9963	MPT0B390		HDAC
	MPT0B390 is an inhibitor of HDAC and a TIMP3 inducer inhibiting tumor growth, metastasis, and angiogenesis.		HDAC
T9929	Ramucirumab		VEGFR
	Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors.		VEGFR
T22086	HA 155	Autotaxin Inhibitor IV	PDE
	HA155 is a boronic acid-based compound, inhibiting ATX with IC50 of 5.7 nM by selectively binding to its catalytic threo...		PDE
T6207	SC144		Interleukin , Apoptosis
	SC144 is an orally active small-molecule gp130 inhibitor.		Interleukin , Apoptosis
T6670	Silymarin	Silybin B	SARS-CoV
	Silymarin (Silybin B) is a polyphenolic flavonoid that extracts from the milk thistle or seeds of Silybum marianum. It i...		SARS-CoV
T3860	Isoliquiritin apioside		NF-κB , p38 MAPK , MMP
	Isoliquiritin apioside, isolated from Glycyrrhizae radix rhizome, significantly decreases PMA-induced increases in MMP9 ...		NF-κB , p38 MAPK , MMP
TQ0317	R1530	R-1530,R 1530	VEGFR , FLT , PDGFR , FGFR
	R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.		VEGFR , FLT , PDGFR , FGFR
T0724	Formononetin	Flavosil,Biochanin B,Formononetol	Apoptosis , FGFR
	Formononetin is an O-methylated isoflavone and a phytoestrogen from the root of Astragalus membranaceus.		Apoptosis , FGFR
T4425	JK-P3		VEGFR
	JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has...		VEGFR
T8846	Beta-Escin	B-escin,AESCINE	Immunology/Inflammation related
	beta-Escin is a natural mixture of triterpenoid saponins isolated from horse chestnut (Aesculus hippocastanum) seeds, ca...		Immunology/Inflammation related
T4586	(Rac)-Arnebin 1	beta, beta-dimethylacrylshikonin	Others
	beta, beta-dimethylacrylshikonin has anti-tumor, anti-inflammatory, anti-immune deficiency and protecting liver.		Others
T2456	Tivozanib	KRN951,AV-951	PDGFR , Ephrin Receptor , VEGFR
	Tivozanib is an orally bioavailable inhibitor of vascular endothelial growth factor receptors (VEGFRs) 1, 2 and 3 with p...		PDGFR , Ephrin Receptor , VEGFR
T6351	MGCD-265 analog	Glesatinib,MGCD-265	c-Met/HGFR , Apoptosis , VEGFR
	MGCD-265-analog (structurally related to MGCD-265) is an orally bioavailable multitargeted tyrosine kinase inhibitor wit...		c-Met/HGFR , Apoptosis , VEGFR
T2690	Tranilast	MK 341,SB 252218	Prostaglandin Receptor , RAAS
	Tranilast, an antiallergic drug, suppresses lipid mediator and cytokine release from inflammatory cells, therefore utili...		Prostaglandin Receptor , RAAS
T1394	Ibuprofen	(±)-Ibuprofe,Advil,Motrin,Brufen	COX
	Ibuprofen is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic...		COX
T7203	Oglufanide	H-Glu-Trp-OH,L-Glutamyl-L-tryptophan	HCV Protease , Endogenous Metabolite , VEGFR
	Oglufanide is a naturally occurring thymic immunomodulator,and inhibits vascular endothelial growth factor (VEGF).		HCV Protease , Endogenous Metabolite , VEGFR