T74627 |
Angiogenesis inhibitor 3
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Angiogenesis inhibitor 3 (compound 8) is a potent angiogenesis inhibitor. Angiogenesis inhibitor 3 inhibits the prolifer... |
T74217 |
Angiogenesis agent 1
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Angiogenesis agent 1 (compound C-31) is a salidroside-derivated glycoside analogue. Angiogenesis agent 1 is an activator... |
T71722 |
Angiogenesis inhibitor BT2
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Angiogenesis inhibitor BT2 is a novel inhibitor of angiogenesis and vascular permeability, inhibiting ERK phosphorylatio... |
T2427 |
EHop-016
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EHop 016 |
Ras
,
Rho
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EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally eff... |
T9963 |
MPT0B390
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HDAC
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MPT0B390 is an inhibitor of HDAC and a TIMP3 inducer inhibiting tumor growth, metastasis, and angiogenesis. |
T9929 |
Ramucirumab
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VEGFR
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Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors. |
T22086 |
HA 155
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Autotaxin Inhibitor IV |
PDE
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HA155 is a boronic acid-based compound, inhibiting ATX with IC50 of 5.7 nM by selectively binding to its catalytic threo... |
T6207 |
SC144
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Interleukin
,
Apoptosis
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SC144 is an orally active small-molecule gp130 inhibitor. |
T6670 |
Silymarin
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Silybin B |
SARS-CoV
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Silymarin (Silybin B) is a polyphenolic flavonoid that extracts from the milk thistle or seeds of Silybum marianum. It i... |
T3860 |
Isoliquiritin apioside
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NF-κB
,
p38 MAPK
,
MMP
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Isoliquiritin apioside, isolated from Glycyrrhizae radix rhizome, significantly decreases PMA-induced increases in MMP9 ... |
TQ0317 |
R1530
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R-1530,R 1530 |
VEGFR
,
FLT
,
PDGFR
,
FGFR
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R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities. |
T0724 |
Formononetin
|
Flavosil,Biochanin B,Formononetol |
Apoptosis
,
FGFR
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Formononetin is an O-methylated isoflavone and a phytoestrogen from the root of Astragalus membranaceus. |
T4425 |
JK-P3
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VEGFR
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JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has... |
T8846 |
Beta-Escin
|
B-escin,AESCINE |
Immunology/Inflammation related
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beta-Escin is a natural mixture of triterpenoid saponins isolated from horse chestnut (Aesculus hippocastanum) seeds, ca... |
T4586 |
(Rac)-Arnebin 1
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beta, beta-dimethylacrylshikonin |
Others
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beta, beta-dimethylacrylshikonin has anti-tumor, anti-inflammatory, anti-immune deficiency and protecting liver. |
T2456 |
Tivozanib
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KRN951,AV-951 |
PDGFR
,
Ephrin Receptor
,
VEGFR
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Tivozanib is an orally bioavailable inhibitor of vascular endothelial growth factor receptors (VEGFRs) 1, 2 and 3 with p... |
T6351 |
MGCD-265 analog
|
Glesatinib,MGCD-265 |
c-Met/HGFR
,
Apoptosis
,
VEGFR
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MGCD-265-analog (structurally related to MGCD-265) is an orally bioavailable multitargeted tyrosine kinase inhibitor wit... |
T2690 |
Tranilast
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MK 341,SB 252218 |
Prostaglandin Receptor
,
RAAS
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Tranilast, an antiallergic drug, suppresses lipid mediator and cytokine release from inflammatory cells, therefore utili... |
T1394 |
Ibuprofen
|
(±)-Ibuprofe,Advil,Motrin,Brufen |
COX
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Ibuprofen is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic... |
T7203 |
Oglufanide
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H-Glu-Trp-OH,L-Glutamyl-L-tryptophan |
HCV Protease
,
Endogenous Metabolite
,
VEGFR
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Oglufanide is a naturally occurring thymic immunomodulator,and inhibits vascular endothelial growth factor (VEGF). |