T12706 |
Reslizumab
|
241473-69-8
|
98%
|
|
Reslizumab is humanized monoclonal antibodies that target interleukin-5 (IL-5) for the treatment of eosinophilic asthma.
|
T4S1057 |
Tripdiolide
|
38647-10-8
|
98%
|
|
Tripdiolide has cytotoxic, and anti-rheumatic activities, it suppresses pro-inflammatory gene expression, may be effective therapy for lupus nephritis.
|
TN4561 |
Methylnissolin
|
733-40-4
|
98%
|
|
Methylnissolin is a natural product from A. membranaceus.
|
TN4130 |
Germacrone 4,5-epoxide
|
92691-35-5
|
98%
|
|
(4S,5S)-(+)-Germacrone-4,5-epoxide inhibits certain subtypes of cytochrome P450 (CYP).
|
TN4648 |
Nepetoidin B
|
55486-06-1
|
98%
|
|
Nepetoidin B has anti-fungal, anti-bacterial, and antiinflammatory effects, it can inhibit LPS-stimulated NO production possibly via modulation of iNOS mediated ...
|
TN3539 |
Broussonin A
|
73731-87-0
|
98%
|
|
Broussonins A and B, new phytoalexins from diseased paper mulberry. Broussonin A shows estrogenic activity with ligand-binding activity of estrogen receptor, tra...
|
TN1549 |
Damnacanthal
|
477-84-9
|
98%
|
|
Damnacanthal possesses anti-cancer, immunomodulatory, antinociceptive and anti-inflammatory actions, it can treat or prevent hepatocellular carcinoma through its...
|
TN4592 |
Murrangatin
|
37126-91-3
|
98%
|
|
Murrangatin may be a valuable anti-tumor-promoting agent, it can significantly inhibit Epstein-Barr virus early antigen (EBV-EA) activation, and preserve the hig...
|
TN4190 |
Hedycoronen A
|
1383441-73-3
|
98%
|
|
Hedycoronen A and hedycoronen B have the potential anti-inflammatory benefits, they are potent inhibitors of LPS-stimulated interleukin-6 (IL-6) and IL-12 p40, w...
|
T11635 |
IL-17A antagonist 1
|
2205034-18-8
|
98%
|
|
IL-17A antagonist 1 is an IL-17A antagonist (Kd: 0.66 μM; IC50: 1.14 μM).
|
TN4420 |
Latifolin
|
10154-42-4
|
98%
|
|
Latifolin is a strong DPPH-scavenger, it attenuates inflammatory responses by inhibiting NF-κB activation via Nrf2-mediated heme oxygenase-1 expression. Latifol...
|
TN2539 |
1beta-Hydroxyalantolactone
|
68776-47-6
|
98%
|
|
1beta-Hydroxyalantolactone has protective effect against AD-like skin inflammation, can as a potential therapeutic agent for AD.
|
TN4288 |
Isoferulic acid
|
25522-33-2
|
98%
|
|
Isoferulic acid is an effective natural antioxidant in both lipid and aqueous media, it may be a new promising anti-glycation agent for the prevention of diabeti...
|
TN1412 |
Astringin
|
29884-49-9
|
98%
|
|
Astringinin is a potent antiarrhythmic agent with cardioprotective activity in ischemic and ischemic-reperfused rat heart, the beneficial effects of astringinin ...
|
TN5011 |
Shizukaol B
|
142279-40-1
|
98%
|
|
Shizukaol B exerts anti-inflammatory effects in LPS-activated microglia partly by modulating JNK-AP-1 signaling pathway; it also shows significant anti-neuroinfl...
|
T10497 |
Benralizumab
|
1044511-01-4
|
98%
|
|
Benralizumab (MEDI-563) is an IL-5Rα-directed cytolytic monoclonal antibody that induces rapid, direct and nearly complete depletion of eosinophils via enhanced ...
|
TN3483 |
Bakkenolide D
|
18456-03-6
|
98%
|
|
Bakkenolide D has anti-allergic effect, it and bakkenolide D demonstrates inhibitory effect on the trachea contraction induced by histamine in vitro, they have o...
|
TN4213 |
Hirsutenone
|
41137-87-5
|
98%
|
|
Hirsutenone has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition effect on the mitochondrial lipid pero...
|
TN5033 |
Skullcapflavone I
|
41060-16-6
|
98%
|
|
Skullcapflavone I has anti-inflammatory and anti-allergic potential, it can significantly inhibit LPS stimulated NO and PGE(2) release in J774A.1 macrophages and...
|
TN1960 |
Mussaenoside
|
64421-27-8
|
98%
|
|
Mussaenoside has anti-inflammatory action, the mechanism associated with downregulation of nuclear factor-κB.
|