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Search Results for " dysfunction "

Targets

177

Compounds

47

Natural Products

89

Recombinant Proteins

4

Libraries

Cat No. Product Name Synonyms Targets
T8348 Phentolamine Adrenergic Receptor
Phentolamine mesylate is an alpha-1 and alpha-2 selective adrenergic receptor antagonist
T19777 ODQ Apoptosis , Others , Guanylate cyclase
ODQ is an effective and selective soluble guanylyl cyclase (sGC) inhibitor.
T1635 Fenchlorphos Ronnel,Dermafos AChE , Parasite
Fenchlorphos (Dermafos) is a cholinesterase inhibitor, used as an insecticide.
T0866 Propafenone Rythmol,Propafenonum Potassium Channel , MRP , Sodium Channel
Propafenone (Propafenonum) is only found in individuals that have used or taken this drug. It is an antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity....
TQ0091 LY2795050 Opioid Receptor
LY2795050 is a novel specific κ-Opioid Receptor antagonist (IC50: 0.72 nM).
T22671 CJ 033466 5-HT Receptor
CJ 033466 is a selective partial agonist of 5-HT4 receptor (EC50 = 9 nM) with gastroprokinetic effect.
T8405 Vardenafil hydrochloride PDE
Vardenafil hydrochloride is a New Phosphodiesterase Type 5(PDE5) Inhibitor, in the Treatment of Erectile Dysfunction in Men With Diabetes
T0096 Vardenafil Vivanza,Levitra,Vardenafil hydrochloride PDE
Vardenafil (Vivanza) is an oral therapy for the treatment of erectile dysfunction. It is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). Penile erection is a hemod...
T5513 RO-3 P2X Receptor
RO3 is a selective antagonist of homomeric P2X3 and heteromeric P2X2/3 receptor
T8494 NS-3-008 hydrochloride NS-3-008 HCl Others
NS-3-008 hydrochloride (NS-3-008 HCl) is a transcriptional G0/G1 switch 2 (G0s2) inhibitor( IC50 of 2.25 μM).
T5183 AUT1 Potassium Channel
AUT1 (AUT-1) is a novel specific modulator of Kv3 channels (EC50: 4.7 and 4.9 uM for Kv3.1b and Kv3.2a).
T4097 Vardenafil hydrochloride trihydrate Vardenafil HCl Trihydrate,BAY38-9456 PDE
Vardenafil hydrochloride trihydrate (BAY38-9456) is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively.
T60080 TMPH 2,2,6,6-Tetramethylpiperidin-4-yl heptanoate AChR
TMPH is an inhibitor of nAChR and inhibits nAChRs lacking α5, α6, or β3 subunits. TMPH can be used in studies about nAChR dysfunction or neurological disorders.
T8390 Cefazolin Others , Antibacterial , Antibiotic
Cefazolin is a semi-synthetic cephalosporin that has a broad spectrum of antibacterial activity and inhibits the synthesis of bacterial cell walls.
T1006 Propantheline bromide Neopepulsan,Pro-Banthine,Neometantyl AChR
Propantheline bromide (Pro-Banthine) competitively antagonizes acetylcholine activity mediated by muscarinic receptors at neuroeffector sites on smooth muscle and exocrine gland cells. Propantheline Bromide is the bromid...
T1275 Phentolamine mesylate Phentolamine methanesulfonate,Phentolamine mesilate Adrenergic Receptor
Phentolamine mesylate (Phentolamine methanesulfonate) is a nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEAS...
T16079 Mirodenafil SK3530 PDE
Mirodenafil is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.
T2334 Avanafil TA1790 PDE
Avanafil (TA1790) is a selective inhibitor of phosphodiesterase type 5 (PDE5) and is used as therapy of erectile dysfunction.
T28178 NLRP3-IN-9 INF-4E,INF 4E,INF4E NOD
NLRP3-IN-9 (INF-4E) is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-triggered pyroptosis of human THP-1 cells in a time- ...
T0787 Butylhydroxyanisole BHA,E320,Butylated hydroxyanisole Antioxidant , Ferroptosis , Reactive Oxygen Species
Butylhydroxyanisole (BHA) is an antioxidant consisting of a mixture of two isomeric organic compounds, 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole.
T1780 Parecoxib SC 69124,Vorth-P,Valus-P COX
Parecoxib (SC 69124) is an effective and selective COX-2 inhibitor.
T23146 PHA 568487 free base PHA 568487 AChR
The quinuclidine PHA 568487 free base is an agonist of the alpha 7 nicotinic acetylcholine receptor that was designed to mitigate the bioactivation associated with the core scaffold and subsequently remove associated lia...
T7313 Enclomiphene citrate Enclomifene citrate,(E)-Clomiphene citrate,trans-Clomiphene citrate Estrogen Receptor/ERR
Enclomiphene citrate (trans-Clomiphene citrate) is a non-steroidal estrogen receptor antagonist,with antioestrogenic property
T19663 Triheptanoin UX 007,IND106011,UX007,UX-007,IND 106011,IND-106011 Others
Triheptanoin (IND 106011) is a fatty acid metabolic modulator. It potentially for the treatment of fatty acid oxidation disorders and GLUT1.
TQ0126 Mirodenafil dihydrochloride SK-3530 dihydrochloride PDE
Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.
T4480 Vardenafil dihydrochloride Levitra,Vardenafil Hydrochloride PDE
Vardenafil dihydrochloride (Levitra) is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively.
T0953 Cefazolin sodium Ancef,Cefazolin sodium salt,Sodium cephazolin,cephazolin sodium,cefazoline sodium,Sodium cefazolin Others , Antibacterial , Antibiotic
Cefazolin sodium (cephazolin sodium) salt binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Cefazolin sodium salt is the sodium salt of cefazolin, a beta...
T1406 Amantadine hydrochloride 1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride Dopamine Receptor , Influenza Virus
Amantadine hydrochloride (CI-719) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A and Parkinson disease.
T31081 CP-866087 CP 866087,UNII-MDH21334PI,CP-866,087,CP866087 Opioid Receptor
CP-866087 is a novel, potent and selective mu-opioid receptor antagonist for the study of female sexual dysfunction.
T20543 Flurochloridone R 40244,R-40244,R40244,EPA Pesticide Chemical Code 128401 Apoptosis , Reactive Oxygen Species
Flurochloridone (R 40244) is a selective herbicide. Flurochloridone induces apoptosis and is regulated by mitochondrial dysfunction and oxidative stresses.
T27122 Dasantafil SCH446132,SCH-446132,SCH 446132 PDE
Dasantafil (SCH446132) is a small molecule phosphodiesterase-5A (PDE5A) inhibitor used to treat genitourinary disorders and study erectile dysfunction.
T24064 Fipamezole JP-1730,BVF-025,JP 1730,JP1730 Adrenergic Receptor
Fipamezole is a potent alpha2 adrenergic receptor antagonist that may be useful for studying autonomic dysfunction in Parkinson's disease.
T14551 Bevenopran CB-5945,ADL-5945 Opioid Receptor
Bevenopran (CB-5945) is a peripheral antagonist of μ-opioid receptor and can be used in studies about the treatment of opioid-induced bowel dysfunction.
T31081L CP 866087 Opioid Receptor
CP 866087 is an opioid receptor antagonist for the study of female sexual dysfunction.
T2264 AM281 Cannabinoid Receptor
AM 281, a cannabinoid antagonist, reduces neurologic dysfunction and mortality rate after cecal ligation and puncture in rats.
T7298 FT011 Others
FT011, a direct anti-fibrotic agent,attenuates cardiac remodelling and dysfunction in experimental diabetic cardiomyopathy.
T27462 GSK-239512 GSK239512,GSK 239512 Histamine Receptor
GSK-239512 is an antagonist of H3 receptor and can be used in studies about the treatment of cognitive dysfunction in neurodegenerative disorders.
T13267 USP30 inhibitor 11 USP30-IN-11 DUB
USP30 inhibitor 11 (USP30-IN-11) is a selective USP30 inhibitor (IC50: 0.01 µΜ) that inhibits SVA and can be used in studies of cancer, mitochondrial dysfunction and Parkinson's.
T3966 Tirasemtiv CK-2017357 Others
Tirasemtiv (CK-2017357)(CK 2017357) is a small-molecule fast-skeletal-troponin activator, with a potential treatment for muscle weakness and neuromuscular dysfunction.
T68000L MK-0533 PPAR
MK-0533 is a novel PPARγ partial agonist for the prevention of vascular endothelial dysfunction (VED) and VED-related cardiovascular disease.
T80673 Chloranil p-Chloranil TLR
Chloranil (tetrachloro-p-benzoquinone) triggers inflammation and neurological dysfunction through Toll-like receptor 4 signaling and can be used to model inflammation in mice.
T7346 Lodenafil Hydroxyhomosildenafil PDE
Lodenafil (Hydroxyhomosildenafil) is a potent PDE5 inhibitor, with treatment of erectile dysfunction (ED)
T0467 Sildenafil citrate UK-92480 citrate Apoptosis , PDE , Autophagy
Sildenafil citrate (UK-92480 citrate) , a cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) Inhibitor, is used extensively for erectile dysfunction and less commonly for pulmonary hypertensio...
T62839 Dalzanemdor SAGE-718 NMDAR , iGluR
Dalzanemdor (SAGE-718) is an NMDA receptor-positive modulator of metabolism that can be used to study Huntington's chorea, Alzheimer's disease, and cognitive dysfunction.
T6147 Nortadalafil Demethyl Tadalafil PDE
Nortadalafil (Demethyl Tadalafil) is demethyl Tadalafil, which is a PDE5 inhibitor, treating erectile dysfunction (ED) ; and under the name Adcirca for the treatment of pulmonary arterial hypertensio.
T7832 Ibrolipim NO-1886 LPL Receptor
Ibrolipim (NO-1886) attenuates high glucose-induced endothelial dysfunction in cultured human umbilical vein endothelial cells via PI3K/Akt pathway.
T71138L Binospirone MDL 73005EF 5-HT Receptor
Binospirone (MDL 73005EF) is a 5-HT1A receptor agonist with anxiolytic activity used in the study of glaucoma and movement disorders associated with neurologic dysfunction.
T6329 3-Aminobenzamide 3-AB,INO1001,INO-1001,3-ABA,PARP-IN-1,INO 1001 PARP
3-Aminobenzamide (PARP-IN-1) is an effective inhibitor of PARP (IC50<50 nM in CHO cells) and a mediator of oxidant-induced myocyte dysfunction during reperfusion.
T40542 Sinbaglustat ACT-519276,Sinbaglustat,OGT2378 Transferase
Sinbaglustat (OGT2378) (OGT2378) is a dual inhibitor of glucose ceramide synthetase (GCS) and non-lysosomal glucose ceramidase (GBA2).Sinbaglustat is an orally administered N-alkyl iminosugar that crosses the blood-brain...
T72662 NMDAR/TRPM4-IN-2 ERK , TRP/TRPV Channel , NMDAR , iGluR
NMDAR/TRPM4-IN-2 is a potent interfacial inhibitor of NMDAR/TRPM4 interaction.NMDAR/TRPM4-IN-2 protects against MCAO-induced brain damage and NMDA-induced retinal ganglion cell loss in mice.NMDAR/TRPM4-IN-2 has neuroprot...

Compounds

Phentolamine
T8348
Synonym:
Target: Adrenergic Receptor
ODQ
T19777
Synonym:
Target: Apoptosis, Others, Guanylate cyclase
Fenchlorphos
T1635
Synonym: Ronnel,Dermafos
Target: AChE, Parasite
Propafenone
T0866
Synonym: Rythmol,Propafenonum
Target: Potassium Channel, MRP, Sodium Channel
LY2795050
TQ0091
Synonym:
Target: Opioid Receptor
CJ 033466
T22671
Synonym:
Target: 5-HT Receptor
Vardenafil hydrochloride
T8405
Synonym:
Target: PDE
Vardenafil
T0096
Synonym: Vivanza,Levitra,Vardenafil hydrochloride
Target: PDE
RO-3
T5513
Synonym:
Target: P2X Receptor
NS-3-008 hydrochloride
T8494
Synonym: NS-3-008 HCl
Target: Others
AUT1
T5183
Synonym:
Target: Potassium Channel
Vardenafil hydrochloride trihydrate
T4097
Synonym: Vardenafil HCl Trihydrate,BAY38-9456
Target: PDE
TMPH
T60080
Synonym: 2,2,6,6-Tetramethylpiperidin-4-yl heptanoate
Target: AChR
Cefazolin
T8390
Synonym:
Target: Others, Antibacterial, Antibiotic
Propantheline bromide
T1006
Synonym: Neopepulsan,Pro-Banthine,Neometantyl
Target: AChR
Phentolamine mesylate
T1275
Synonym: Phentolamine methanesulfonate,Phentolamine mesilate
Target: Adrenergic Receptor
Mirodenafil
T16079
Synonym: SK3530
Target: PDE
Avanafil
T2334
Synonym: TA1790
Target: PDE
NLRP3-IN-9
T28178
Synonym: INF-4E,INF 4E,INF4E
Target: NOD
Butylhydroxyanisole
T0787
Synonym: BHA,E320,Butylated hydroxyanisole
Target: Antioxidant, Ferroptosis, Reactive Oxygen Species
Parecoxib
T1780
Synonym: SC 69124,Vorth-P,Valus-P
Target: COX
PHA 568487 free base
T23146
Synonym: PHA 568487
Target: AChR
Enclomiphene citrate
T7313
Synonym: Enclomifene citrate,(E)-Clomiphene citrate,trans-Clomiphene citrate
Target: Estrogen Receptor/ERR
Triheptanoin
T19663
Synonym: UX 007,IND106011,UX007,UX-007,IND 106011,IND-106011
Target: Others
Mirodenafil dihydrochloride
TQ0126
Synonym: SK-3530 dihydrochloride
Target: PDE
Vardenafil dihydrochloride
T4480
Synonym: Levitra,Vardenafil Hydrochloride
Target: PDE
Cefazolin sodium
T0953
Synonym: Ancef,Cefazolin sodium salt,Sodium cephazolin,cephazolin sodium,cefazoline sodium,Sodium cefazolin
Target: Others, Antibacterial, Antibiotic
Amantadine hydrochloride
T1406
Synonym: 1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride
Target: Dopamine Receptor, Influenza Virus
CP-866087
T31081
Synonym: CP 866087,UNII-MDH21334PI,CP-866,087,CP866087
Target: Opioid Receptor
Flurochloridone
T20543
Synonym: R 40244,R-40244,R40244,EPA Pesticide Chemical Code 128401
Target: Apoptosis, Reactive Oxygen Species
Dasantafil
T27122
Synonym: SCH446132,SCH-446132,SCH 446132
Target: PDE
Fipamezole
T24064
Synonym: JP-1730,BVF-025,JP 1730,JP1730
Target: Adrenergic Receptor
Bevenopran
T14551
Synonym: CB-5945,ADL-5945
Target: Opioid Receptor
CP 866087
T31081L
Synonym:
Target: Opioid Receptor
AM281
T2264
Synonym:
Target: Cannabinoid Receptor
FT011
T7298
Synonym:
Target: Others
GSK-239512
T27462
Synonym: GSK239512,GSK 239512
Target: Histamine Receptor
USP30 inhibitor 11
T13267
Synonym: USP30-IN-11
Target: DUB
Tirasemtiv
T3966
Synonym: CK-2017357
Target: Others
MK-0533
T68000L
Synonym:
Target: PPAR
Chloranil
T80673
Synonym: p-Chloranil
Target: TLR
Lodenafil
T7346
Synonym: Hydroxyhomosildenafil
Target: PDE
Sildenafil citrate
T0467
Synonym: UK-92480 citrate
Target: Apoptosis, PDE, Autophagy
Dalzanemdor
T62839
Synonym: SAGE-718
Target: NMDAR, iGluR
Nortadalafil
T6147
Synonym: Demethyl Tadalafil
Target: PDE
Ibrolipim
T7832
Synonym: NO-1886
Target: LPL Receptor
Binospirone
T71138L
Synonym: MDL 73005EF
Target: 5-HT Receptor
3-Aminobenzamide
T6329
Synonym: 3-AB,INO1001,INO-1001,3-ABA,PARP-IN-1,INO 1001
Target: PARP
Sinbaglustat
T40542
Synonym: ACT-519276,Sinbaglustat,OGT2378
Target: Transferase
NMDAR/TRPM4-IN-2
T72662
Synonym:
Target: ERK, TRP/TRPV Channel, NMDAR, iGluR
1 2 3 4
Cat No. Product Name Synonyms Targets
TN4417 Larixyl acetate Others
Larixyl acetate is a bioactive chemical.
TN1969 N-(p-Coumaroyl) serotonin PDGFR
N-(p-Coumaroyl) Serotonin is a polyphenol isolated from the seeds of safflower. N-(p-Coumaroyl) serotonin has antioxidant, cardioprotective effects after ischemia and antitumor activity, it may be beneficial in improving...
T11685 Isolongifolene (-)-Isolongifolene Apoptosis , Others
Isolongifolene ((-)-Isolongifolene), a tricyclic sesquiterpene isolated from Murraya koenigii, exhibits antioxidant, anti-inflammatory, anticancer, and neuroprotective properties. It mitigates Rotenone-induced oxidative ...
T3410 Momordin Ic Momordin 1c Apoptosis , MAPK , PI3K
Momordin Ic (Momordin 1c) might represent a potential anticancer activity, by inducing apoptosis through oxidative stress-regulated mitochondrial dysfunction involving the MAPK and PI3K-mediated iNOS and HO-1 pathways. A...
T5645 Nerol Cis-Geraniol,Neryl alcohol Apoptosis , Reactive Oxygen Species , Mitochondrial Metabolism , Endogenous Metabolite , Antifungal
Nerol (Neryl alcohol) is a monoterpene found in many essential oils, such as lemon balm and hop.Nerol can lessened the severity of ouabain-triggered arrhythmias in mammalian heart.
T3999 D(+)-Galactosamine hydrochloride D-Galactosamine HCl Others
D(+)-Galactosamine hydrochloride (D-Galactosamine HCl) hepatotoxicity is associated with endotoxin sensitivity and mediated by lymphoreticular cells in mice.
T6975 Sarcosine Sarcosinic acid,Methylaminoacetic acid,Sarcosin,Methylglycine,N-Methylaminoacetic acid,N-methylglycine Others , GlyT , Endogenous Metabolite
Sarcosine (Methylglycine) is a competitive inhibitor of the type I glycine transporter (GlyT1) and an N-methyl-D-aspartate receptor (NMDAR) co-agonist.
T5247 Trimethylamine N-oxide dihydrate TMANO Dihydrate Others , Endogenous Metabolite
Trimethylamine N-oxide dihydrate (TMANO Dihydrate), a product of the oxidation of trimethylamine, is considered as a protein stabilizer that may serve to counteract urea, the major osmolyte of sharks, skates and rays.
T7060 Amantadine 1-Aminoadamantane,1-Adamantanamine,1-Adamantylamine Others
Amantadine (1-Aminoadamantane) is an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release, and blocks dopamine reuptake.
T19466 N8-Acetylspermidine dihydrochloride Endogenous Metabolite
N8-Acetylspermidine dihydrochloride is a polyamine.
T5665 Geraniol Others , Endogenous Metabolite , Antifungal
geraniol provides a potent protective effect against cardiac dysfunction induced by diabetes. This ameliorative effect could be attributed to its suppression of oxidative stress.
TN1594 DL-Syringaresinol (±)-Syringaresinol Antioxidant , Antifungal
DL-Syringaresinol ( (±)-Syringaresinol) is a lignan from ginseng berries with anti-inflammatory, antioxidant, analgesic and weak anti-mycobacterial activities.DL-Syringaresinol can delay oxidative stress-induced skin agi...
T6S1294 Nicotiflorin Nictoflorin,Kaempferol-3-O-Rutinoside,Nicotifloroside Others
1. Nicotiflorin (Kaempferol-3-O-Rutinoside) has potential therapeutic effects on cerebral ischemic illness. 2. Nicotiflorin has protective effects on reducing memory dysfunction, energy metabolism failure and oxidative s...
T3916 Ginsenoside F2 Apoptosis , Endogenous Metabolite , Autophagy
Ginsenoside F2 has antiproliferative activity against breast cancer stem cells (CSCs). It induces apoptosis in breast CSCs by activating the intrinsic apoptotic pathway and mitochondrial dysfunction.
T17056 Tetrahydrobiopterin Sapropterin,BH4,(Rac)-Sapropterin NOS , Endogenous Metabolite
Tetrahydrobiopterin (BH4) is a cofactor for aromatic amino acid hydroxylases and an essential cofactor for nitric oxide synthase (NOS), which is used in the study of endothelial dysfunction such as hypertension, hypercho...
T2142 Yohimbine hydrochloride Antagonil,Yohimbine HCl Adrenergic Receptor
Yohimbine hydrochloride (Antagonil) is a plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of ERECTILE DYSFUNCTION.
TN1461 (-)-Butin Butin Akt , PI3K , Nrf2
(-)-Butin (Butin) has antioxidant activity, can protect cells against H2O2-induced apoptosis, oxidative DNA damage and oxidative mitochondrial dysfunction; it attenuates oxidative stress by activating Nrf2-mediated Mn SO...
TN1895 Luteolinidin chloride CD38
Luteolinidin chloride is a natural product. It is a potent CD38 inhibitor which can protect the heart against I/R injury with preservation of eNOS function and prevention of endothelial dysfunction in vivo.
T5076 L-Allothreonine L-allo-Threonine Others , Endogenous Metabolite
L-Allothreonine (L-allo-Threonine) is an essential amino acid in humans. L-Allothreonine is abundant in human plasma, particularly in newborns. Severe deficiency of threonine causes neurological dysfunction and lameness ...
T20793 Magnesium Lithospermate B Monomethyl lithospermate B,Lithospermate B Others
Magnesium Lithospermate B is a natural product activates eNOS and ameliorates endothelial dysfunction in diabetes by enhancing vasodilation in addition to reducing oxidative stress, it can protecte cardiomyocytes from is...
T3S1068 Oxyresveratrol trans-Oxyresveratrol,2,3',4,5'-tetrahydroxystilbene,Tetrahydroxystilbene Tyrosinase , Autophagy , HSV
1. Oxyresveratro can inhibit tyrosinase activity. 2. Oxyresveratro is useful to trauma models, as toxicity to glia could be beneficial by inhibiting reactive gliosis. 3. Oxyresveratrol (trans-Oxyresveratrol) has antioxid...
TN1042 Chebulic acid Others
Chebulic acid, a phenolcarboxylic acid compound isolated from Terminalia chebula, has potent anti-oxidant activity,which breaks the cross-links of proteins induced by advanced glycation end-products (AGEs) and inhibits t...
T1626 Prostaglandin E1 PGE1,Alprostadil Endogenous Metabolite , Prostaglandin Receptor
Prostaglandin E1 (Alprostadil) is the naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Prostaglandin E1 is a potent vasodilator agent that increases peripheral blood flow, in...
T3403 Glabridin Q-100692,KB-289522,LS-176045 Reactive Oxygen Species , Tyrosinase , GABA Receptor , Antibacterial , PPAR
Glabridin (KB-289522) may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS under high-glucose levels; may possess a therapeutic effect on...
T2836 Isorhamnetin 3-methylquercetin,3'-Methylquercetin,Isorhamnetol,3'-Methoxyquercetin MEK , PI3K , Endogenous Metabolite
Isorhamnetin (3-methylquercetin) is the methylated metabolite of quercetin. Quercetin is an important dietary flavonoid with in vitro antioxidant activity. Isorhamnetin prevents endothelial cell injuries from oxidized LD...
T3895 Polyphyllin I Apoptosis , Akt , JNK , PDK , mTOR , Autophagy
Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C, and cleaved-caspase-3 levels. Polyphyllin D ha...
T3578 Pyridoxal phosphate PLP,PAL-P,pyridoxal 5'-phosphate,Pyridoxyl phosphate,Pyridoxal 5′-phosphate,Vitamin B6 phosphate Reverse Transcriptase , Endogenous Metabolite
Pyridoxal phosphate (Vitamin B6 phosphate) is the active form of vitamin B6 and a coenzyme for many pyridoxal phosphate (PLP)-dependent enzymes. PLP is involved in numerous enzymatic transamination, decarboxylation and d...
T6S0735 Flavokawain B Flavokavain B,Flavokawin B,2'-Hydroxy-4',6'-Dimethoxychalcone Apoptosis , Others
1. Flavokawain B (Flavokavain B) has potent anti-inflammatory activity, can significantly inhibit production of NO and PGE2 in LPS-induced RAW 264.7 cells. 2. Flavokawain B, the hepatotoxic constituent from kava root, in...
T37974 (S)-Coriolic acid 13(S)-HODE Lipoxygenase , Mitochondrial Metabolism , PPAR
(S)-Coriolic acid (13(S)-HODE) is an important intracellular signaling agent, generated by the reaction of linoleic acid with plant and mammalian lipoxygenases, and is involved in cell proliferation and differentiation i...
T19496 Oleuroside Others
Oleuroside can protect against mitochondrial dysfunction in models of early Alzheimer's disease and brain ageing.
TN1910 Malvidin chloride ROS
Malvidin chloride has anti-spermatogenic, and antioxidant activities. It can prevent endothelial dysfunction by inhibiting ROS and XO-1.
TMA0237 Carlinoside Nrf2
Carlinoside could be a worthy choice to intervene hyperbilirubinemia due to liver dysfunction. Carlinoside upregulates Nrf2 gene expression, increases its nuclear translocation and stimulates UGT1A1 promoter activity.
TN3618 Cedrin Beta Amyloid , BCL , Caspase
Cedrin has protective effects on PC12 cells against the neurotoxicity induced by amyloid β1-42, the protective effect is related to the inhibition of oxidative stress, improvement of mitochondrial dysfunction and suppres...
TN6608 Cyanidin-3-O-arabinoside chloride
Cyanidin-3-O-arabinoside chloride has antioxidant activity. It reduces the peroxynitrite-induced suppression of mitochondrial respiration, DNA damage, PARS activation and vascular dysfunction in HUVECs.
T10554 Bixin Others
Bixin is isolated from the seeds of Bixa orellana and possesses anti-tumor, anti-inflammatory, and antioxidant activities. Bixin treatment ameliorated cardiac dysfunction through inhibiting fibrosis, inflammation, and RO...
TN1093 Ginsenoside F4 MMP , IL Receptor , BCL
Ginsenoside F4 has inhibitory effect on human lymphocytoma JK cell by inducing its apoptosis, the mechanism is related to the mitochondrial dysfunction and the increase of Bax expression and decrease of Bcl-2 expression.
TN5013 Shizukaol D AMPK
Shizukaol D exerts a growth inhibition effect on liver cancer cells in a dose- and time-dependent manner by modulating wnt signalling pathway. Shizukaol D may be used to treat metabolic syndrome, it induces mitochondrial...
TN1086 Dehydrotrametenolic acid Dehydroeburicoic acid Apoptosis , TNF , NOS , Caspase , NO Synthase
Dehydrotrametenolic acid (Dehydroeburicoic acid) induces necrotic cell death that involves Ca(2+) overload, mitochondrial dysfunction, and calpain activation in human glioblastomas.
TN5440 Catechin-7-O-xyloside Catechin 7-O-β-D-xylopyranoside Others
Catechin-7-O-xyloside(C7Ox) has anti-cancer activity, it induces apoptosis via endoplasmic reticulum stress and mitochondrial dysfunction in human non-small cell lung carcinoma H1299 cells.
T78466 Erythronic acid potassium Endogenous Metabolite
Potassium erythronate is an intrinsic carbohydrate metabolite utilized in researching metabolic diseases. It significantly influences the development and mitigation of hyperuricemia and associates with mitochondrial dysf...
T5255 5-Hydroxymethyluracil 5-(Hydroxymethyl)uracil,Hydroxymethyl Uracil,a-Hydroxythymine Others , Endogenous Metabolite
5-Hydroxymethyluracil (a-Hydroxythymine) is an oxidation damage product derived from thymine or 5-methylcytosine. 5-Hydroxymethyluracil is a product of thymine dioxygenase. Additional deamination products such as 5-hydro...
T38250 L-Sepiapterin
L-Sepiapterin, also known as Sepiapterin, is a precursor compound crucial for the production of tetrahydrobiopterin (BH4), which serves as a coenzyme for endothelial nitric oxide synthase (eNOS). This compound demonstrat...
TN5456 Isoerysenegalensein E
Isoerysenegalensein E shows anti-estrogenic activity comparable to that of 4-hydroxytamoxifen, a typical estrogen receptor antagonist. It shows significant cytotoxicity against HL-60 cells, it induces apoptosis in HL-60 ...
T82773 Catechin 7-O-β-D-glucopyranoside
Catechin 7-O-β-D-glucopyranoside, a natural product identified in Ulmus davidiana and Paeonia obovata, demonstrates oral activity and possesses antioxidant and anti-inflammatory properties. It mitigates mitochondrial dys...
TN5264 Xanthoxyletin TNF , NOS , ROS , COX , Antifection
Xanthoxyletin shows potent antibacterial, fungicidal, and algicidal properties, it also has anticancer, and anti-inflammatory activities. It shows an inhibitory effect on iNOS protein expression at 10 microM, it also can...
T73068 Mammea A/BA
Mammea A/BA demonstrates significant efficacy in inhibiting Trypanosoma cruzi (T. cruzi), through mechanisms such as mitochondrial dysfunction, increased production of reactive oxygen species (ROS), and DNA fragmentation...
TN1094 Ginsenoside Rg6 Apoptosis , NF-κB
Ginsenoside Rg6 can inhibit JK cell proliferation in human lymphocytoma and induce its apoptosis, the mechanism may through mitochondrial dysfunction and an increase of Bax expression and decrease of Bcl-2 expression.

Natural Products

Larixyl acetate
TN4417
Synonym:
Target: Others
N-(p-Coumaroyl) serotonin
TN1969
Synonym:
Target: PDGFR
Isolongifolene
T11685
Synonym: (-)-Isolongifolene
Target: Apoptosis, Others
Momordin Ic
T3410
Synonym: Momordin 1c
Target: Apoptosis, MAPK, PI3K
Nerol
T5645
Synonym: Cis-Geraniol,Neryl alcohol
Target: Apoptosis, Reactive Oxygen Species, Mitochondrial Metabolism, Endogenous Metabolite, Antifungal
D(+)-Galactosamine hydrochloride
T3999
Synonym: D-Galactosamine HCl
Target: Others
Sarcosine
T6975
Synonym: Sarcosinic acid,Methylaminoacetic acid,Sarcosin,Methylglycine,N-Methylaminoacetic acid,N-methylglycine
Target: Others, GlyT, Endogenous Metabolite
Trimethylamine N-oxide dihydrate
T5247
Synonym: TMANO Dihydrate
Target: Others, Endogenous Metabolite
Amantadine
T7060
Synonym: 1-Aminoadamantane,1-Adamantanamine,1-Adamantylamine
Target: Others
N8-Acetylspermidine dihydrochloride
T19466
Synonym:
Target: Endogenous Metabolite
Geraniol
T5665
Synonym:
Target: Others, Endogenous Metabolite, Antifungal
DL-Syringaresinol
TN1594
Synonym: (±)-Syringaresinol
Target: Antioxidant, Antifungal
Nicotiflorin
T6S1294
Synonym: Nictoflorin,Kaempferol-3-O-Rutinoside,Nicotifloroside
Target: Others
Ginsenoside F2
T3916
Synonym:
Target: Apoptosis, Endogenous Metabolite, Autophagy
Tetrahydrobiopterin
T17056
Synonym: Sapropterin,BH4,(Rac)-Sapropterin
Target: NOS, Endogenous Metabolite
Yohimbine hydrochloride
T2142
Synonym: Antagonil,Yohimbine HCl
Target: Adrenergic Receptor
(-)-Butin
TN1461
Synonym: Butin
Target: Akt, PI3K, Nrf2
Luteolinidin chloride
TN1895
Synonym:
Target: CD38
L-Allothreonine
T5076
Synonym: L-allo-Threonine
Target: Others, Endogenous Metabolite
Magnesium Lithospermate B
T20793
Synonym: Monomethyl lithospermate B,Lithospermate B
Target: Others
Oxyresveratrol
T3S1068
Synonym: trans-Oxyresveratrol,2,3',4,5'-tetrahydroxystilbene,Tetrahydroxystilbene
Target: Tyrosinase, Autophagy, HSV
Chebulic acid
TN1042
Synonym:
Target: Others
Prostaglandin E1
T1626
Synonym: PGE1,Alprostadil
Target: Endogenous Metabolite, Prostaglandin Receptor
Glabridin
T3403
Synonym: Q-100692,KB-289522,LS-176045
Target: Reactive Oxygen Species, Tyrosinase, GABA Receptor, Antibacterial, PPAR
Isorhamnetin
T2836
Synonym: 3-methylquercetin,3'-Methylquercetin,Isorhamnetol,3'-Methoxyquercetin
Target: MEK, PI3K, Endogenous Metabolite
Polyphyllin I
T3895
Synonym:
Target: Apoptosis, Akt, JNK, PDK, mTOR, Autophagy
Pyridoxal phosphate
T3578
Synonym: PLP,PAL-P,pyridoxal 5'-phosphate,Pyridoxyl phosphate,Pyridoxal 5′-phosphate,Vitamin B6 phosphate
Target: Reverse Transcriptase, Endogenous Metabolite
Flavokawain B
T6S0735
Synonym: Flavokavain B,Flavokawin B,2'-Hydroxy-4',6'-Dimethoxychalcone
Target: Apoptosis, Others
(S)-Coriolic acid
T37974
Synonym: 13(S)-HODE
Target: Lipoxygenase, Mitochondrial Metabolism, PPAR
Oleuroside
T19496
Synonym:
Target: Others
Malvidin chloride
TN1910
Synonym:
Target: ROS
Carlinoside
TMA0237
Synonym:
Target: Nrf2
Cedrin
TN3618
Synonym:
Target: Beta Amyloid, BCL, Caspase
Cyanidin-3-O-arabinoside chloride
TN6608
Synonym:
Target:
Bixin
T10554
Synonym:
Target: Others
Ginsenoside F4
TN1093
Synonym:
Target: MMP, IL Receptor, BCL
Shizukaol D
TN5013
Synonym:
Target: AMPK
Dehydrotrametenolic acid
TN1086
Synonym: Dehydroeburicoic acid
Target: Apoptosis, TNF, NOS, Caspase, NO Synthase
Catechin-7-O-xyloside
TN5440
Synonym: Catechin 7-O-β-D-xylopyranoside
Target: Others
Erythronic acid potassium
T78466
Synonym:
Target: Endogenous Metabolite
5-Hydroxymethyluracil
T5255
Synonym: 5-(Hydroxymethyl)uracil,Hydroxymethyl Uracil,a-Hydroxythymine
Target: Others, Endogenous Metabolite
L-Sepiapterin
T38250
Synonym:
Target:
Isoerysenegalensein E
TN5456
Synonym:
Target:
Catechin 7-O-β-D-glucopyranoside
T82773
Synonym:
Target:
Xanthoxyletin
TN5264
Synonym:
Target: TNF, NOS, ROS, COX, Antifection
Mammea A/BA
T73068
Synonym:
Target:
Ginsenoside Rg6
TN1094
Synonym:
Target: Apoptosis, NF-κB

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-02881 RAGE Protein, Human, Recombinant Human HEK293
Receptor for Advanced Glycosylation End Products (RAGE, or AGER) is a member of the immunoglobulin super-family transmembrane proteins, as a signal transduction receptor which binds advanced glycation endproducts, certai...
TMPY-02927 RAGE Protein, Human, Recombinant (His) Human HEK293
Receptor for Advanced Glycosylation End Products (RAGE, or AGER) is a member of the immunoglobulin super-family transmembrane proteins, as a signal transduction receptor which binds advanced glycation endproducts, certai...
TMPY-03762 E-Cadherin/Cadherin-1 Protein, Human, Recombinant (hFc) Human HEK293
Cadherins are calcium-dependent cell adhesion proteins which preferentially interact with themselves in a homophilic manner in connecting cells, and thus may contribute to the sorting of heterogeneous cell type. E-cadher...
TMPY-01650 CD131 Protein, Human, Recombinant (His) Human HEK293
Colony stimulating factor 2 receptor, beta, low-affinity (CSF2RB) also known as CD131 antigen (CD131), cytokine receptor common subunit beta, GM-CSF/IL-3/IL-5 receptor common beta-chain, interleukin 3 receptor/granulocyt...
TMPY-01725 Leptin Receptor Protein, Human, Recombinant (His) Human HEK293
Leptin Receptor or CD295 belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-spe...
TMPY-01028 Ficolin 1/FCN1 Protein, Human, Recombinant (His) Human HEK293
Ficolins are humoral molecules of the innate immune systems which recognize carbohydrate molecules on pathogens, apoptotic and necrotic cells. The Ficolin family of proteins are characterized by the presence of a leader ...
TMPY-01209 IL-7R alpha/CD127 Protein, Human, Recombinant (His) Human HEK293
Interleukin 7 Receptor alpha (IL-7RA), also known as CD127, is a 75 kDa hematopoietic receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7 receptor alp...
TMPY-00635 IL-7R alpha/CD127 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Interleukin 7 Receptor alpha (IL-7RA), also known as CD127, is a 75 kDa hematopoietic receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7 receptor alp...
TMPK-00751 FSTL3 Protein, Human, Recombinant (His) Human HEK293
Follistatin-like 3 (FSTL3) is a novel cytokine that regulates insulin sensitivity and counteracts activin/myostatin signalling. In the present study, regulation of FSTL3 in renal dysfunction was investigated in both huma...
TMPY-03227 CISD1 Protein, Human, Recombinant (His) Human E. coli
Mitochondrial dysfunction is thought to play a significant role in neurodegeneration observed in Parkinson's disease (PD), the loss of mitoNEET (CISD1), an iron-sulfur containing protein that regulates mitochondrial bioe...
TMPJ-01083 Serpin E2 Protein, Mouse, Recombinant (His) Mouse Human Cells
Serpin E2 is a member of the Serpin superfamily. It is differentially expressed during neuronal differentiation and is able to transform human embryonic kidney cells into neuronlike cells. Its over-expression in mice lea...
TMPY-00518 SBDS Protein, Human, Recombinant (His) Human E. coli
The mutation of Shwachman-Bodian-Diamond syndrome (SBDS) gene has been proposed to be a major causative reason for SDS. Shwachman-Diamond syndrome (SDS) is a rare pediatric disease characterized by various systemic disor...
TMPY-03353 CEL Protein, Mouse, Recombinant (His) Mouse Baculovirus-Insect Cells
CEL-maturity onset diabetes of the young (MODY), diabetes with pancreatic lipomatosis and exocrine dysfunction, is due to dominant frameshift mutations in the acinar cell carboxyl ester lipase gene (CEL). Bile-salt activ...
TMPY-00452 SBDS Protein, Mouse, Recombinant (His) Mouse E. coli
The mutation of Shwachman-Bodian-Diamond syndrome (SBDS) gene has been proposed to be a major causative reason for SDS. Shwachman-Diamond syndrome (SDS) is a rare pediatric disease characterized by various systemic disor...
TMPY-04773 TPK1 Protein, Human, Recombinant (His) Human E. coli
Thiamine pyrophosphokinase (TPK) produces thiamine pyrophosphate, a cofactor for a number of enzymes, including pyruvate dehydrogenase and 2-ketoglutarate dehydrogenase. Episodic encephalopathy type thiamine metabolism d...
TMPH-03728 Zaire ebolavirus (strain Kikwit-95) VP40 Protein (His & Myc) ZEBOV Baculovirus
Plays an essential role virus particle assembly and budding. Acts by interacting with viral ribonucleocapsid and host members of the ESCRT (endosomal sorting complex required for transport) system such as host VPS4, PDCD...
TMPH-03727 Zaire ebolavirus (strain Kikwit-95) VP40 Protein (His) ZEBOV E. coli
Plays an essential role virus particle assembly and budding. Acts by interacting with viral ribonucleocapsid and host members of the ESCRT (endosomal sorting complex required for transport) system such as host VPS4, PDCD...
TMPY-01929 ECE1 Protein, Human, Recombinant (His) Human HEK293
Endothelin-converting enzyme 1, also known as ECE-1, is a single-pass type II membrane protein which belongs to thepeptidase M13 family. ECE-1 converts big endothelin-1 to endothelin-1. ECE-1 is a membrane metalloprot...
TMPJ-01002 SGSH Protein, Human, Recombinant (His) Human Human Cells
N-Sulphoglucosamine Sulphohydrolase (SGSH) is an important member of the sulfatase family which is involved in the degradation of heparin sulfate. SGSH binds one calcium ion per subunit as a cofactor. SGSH catalyzes N-su...
TMPK-01069 TMEM106B Protein, Mouse, Recombinant (hFc) Mouse HEK293
TMEM106B is a well-recognised risk factor for FTD caused by GRN mutation. Elegant experiments have suggested that increased risk for FTD is due to elevated levels of TMEM106B (Nicholson et al, 2013; Gallagher et al, 2017...
TMPJ-00834 ACADM Protein, Human, Recombinant (His) Human E. coli
Medium-Chain Specific Acyl-CoA Dehydrogenase (ACADM) is a mitochondrial fatty acid beta-oxidation that belongs to the acyl-CoA dehydrogenase family. ACADM is a homotetramer enzyme that catalyzes the initial step of the m...
TMPY-03175 Claudin-11 Protein, Human, Recombinant (mFc) Human HEK293
Claudin-11, also known as CLDN11, belongs to the group of claudins. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands function as a physical barrier to prevent solut...
TMPY-04620 Neurofascin Protein, Human, Recombinant (hFc) Human HEK293
NFASC (Neurofascin, also known as NRCAML, NEDCPMD, and NF) is a Protein Coding gene. 13 alternatively spliced human isoforms have been reported. NFASC belongs to the immunoglobulin superfamily, L1/neurofascin/NgCAM famil...
TMPY-01455 TIM-1/KIM-1/HAVCR1 Protein, Rat, Recombinant (His) Rat HEK293
HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulin mucin 1 (TIM-1), is a type of integral membrane glycoprotein. KIM-1 protein is widely expressed with the highest ...
TMPY-01768 TIM-1/KIM-1/HAVCR1 Protein, Human, Recombinant (His) Human HEK293
HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulin mucin 1 (TIM-1), is a type of integral membrane glycoprotein. KIM-1 protein is widely expressed with the highest ...
TMPY-04280 TIM-1/KIM-1/HAVCR1 Protein, Canine, Recombinant (mFc) Canine HEK293
HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulin mucin 1 (TIM-1), is a type of integral membrane glycoprotein. KIM-1 protein is widely expressed with the highest ...
TMPY-01317 TIM-1/KIM-1/HAVCR1 Protein, Rat, Recombinant (His & hFc) Rat HEK293
HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulin mucin 1 (TIM-1), is a type of integral membrane glycoprotein. KIM-1 protein is widely expressed with the highest ...
TMPY-01671 TIM-1/KIM-1/HAVCR1 Protein, Rhesus, Recombinant (His) Rhesus HEK293
HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulin mucin 1 (TIM-1), is a type of integral membrane glycoprotein. KIM-1 protein is widely expressed with the highest ...
TMPY-01161 TIM-1/KIM-1/HAVCR1 Protein, Human, Recombinant (His & hFc) Human HEK293
HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulin mucin 1 (TIM-1), is a type of integral membrane glycoprotein. KIM-1 protein is widely expressed with the highest ...
TMPY-03797 Neurofascin Protein, Human, Recombinant (His) Human HEK293
NFASC (Neurofascin, also known as NRCAML, NEDCPMD, and NF) is a Protein Coding gene. 13 alternatively spliced human isoforms have been reported. NFASC belongs to the immunoglobulin superfamily, L1/neurofascin/NgCAM famil...
TMPY-02394 IMPA1 Protein, Human, Recombinant (His) Human E. coli
IMPA1 (Inositol Monophosphatase 1) is a Protein Coding gene. This gene encodes an enzyme that dephosphorylates Myo-inositol monophosphate to generate free Myo-inositol, a precursor of phosphatidylinositol, and is, theref...
TMPY-05268 Neurofascin Protein, Human, Recombinant (hFc), Biotinylated Human HEK293
NFASC (Neurofascin, also known as NRCAML, NEDCPMD, and NF) is a Protein Coding gene. 13 alternatively spliced human isoforms have been reported. NFASC belongs to the immunoglobulin superfamily, L1/neurofascin/NgCAM famil...
TMPY-02622 Aldolase B Protein, Human, Recombinant (GST) Human E. coli
The aldolase family members involved in metabolism and glycolysis are present in three isoforms: ALDOA, ALDOB, and ALDOC. Aldolases are differentially expressed in human tissues, and aberrant expression has been observed...
TMPY-06810 SFTPB Protein, Human, Recombinant (His) Human CHO
Pulmonary surfactant-associated protein B, also known as SFTPB and SP-B, contains one saposin A-type domain and three saposin B-type domains. SP-B is produced primarily by alveolar type II cells (AEC2) but also by noncil...
TMPJ-01034 TIM Protein, Human, Recombinant (His) Human E. coli
Triose-phosphate isomerase, also named Triose-phosphate isomerase, TPI and TIM, is an enzyme that catalyzes the reversible interconversion of the triose phosphate isomers dihydroxyacetone phosphate and D-glyceraldehyde 3...
TMPY-01244 TIM-1/KIM-1/HAVCR1 Protein, Mouse, Recombinant (His & hFc) Mouse HEK293
HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulin mucin 1 (TIM-1), is a type of integral membrane glycoprotein. KIM-1 protein is widely expressed with the highest ...
TMPY-01350 TIM-1/KIM-1/HAVCR1 Protein, Canine, Recombinant (His) Canine HEK293
HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulin mucin 1 (TIM-1), is a type of integral membrane glycoprotein. KIM-1 protein is widely expressed with the highest ...
TMPY-01173 TIM-1/KIM-1/HAVCR1 Protein, Human, Recombinant (aa 1-135, His) Human HEK293
HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulin mucin 1 (TIM-1), is a type of integral membrane glycoprotein. KIM-1 protein is widely expressed with the highest ...
TMPY-01951 TIM-1/KIM-1/HAVCR1 Protein, Rhesus, Recombinant Rhesus HEK293
HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulin mucin 1 (TIM-1), is a type of integral membrane glycoprotein. KIM-1 protein is widely expressed with the highest ...
TMPY-03884 Beta-amyloid 39/Beta-APP39 Protein, Human, Recombinant (aa 672-710, His & GST) Human E. coli
Amyloid precursor protein (APP) is a type I transmembrane protein expressed in many tissues and concentrated in the synapses of neurons, and is suggested as a regulator of synapse formation and neural plasticity. APP can...
TMPY-03885 Beta-amyloid 38/Beta-APP38 Protein, Human, Recombinant (aa 672-709, His & GST) Human E. coli
Amyloid precursor protein (APP) is a type I transmembrane protein expressed in many tissues and concentrated in the synapses of neurons, and is suggested as a regulator of synapse formation and neural plasticity. APP can...
TMPY-02110 Beta-amyloid 40/Beta-APP40 Protein, Human, Recombinant (His & GST) Human E. coli
Amyloid precursor protein (APP) is a type I transmembrane protein expressed in many tissues and concentrated in the synapses of neurons, and is suggested as a regulator of synapse formation and neural plasticity. APP can...
TMPY-02221 Beta-amyloid 42/Beta-APP42 Protein, Human, Recombinant (His & GST) Human E. coli
Amyloid precursor protein (APP) is a type I transmembrane protein expressed in many tissues and concentrated in the synapses of neurons, and is suggested as a regulator of synapse formation and neural plasticity. APP can...
TMPY-02406 CD302 Protein, Mouse, Recombinant (hFc) Mouse HEK293
CD302/CLEC13A (C-type lectin domain family 13 member A), also known as C-type lectin receptor DCL-1, is a type I transmembrane C-type lectin DCL-1/CD302. DCL-1 protein was highly conserved among the human, mouse, and rat...
TMPY-02407 CD302 Protein, Mouse, Recombinant (His) Mouse HEK293
CD302/CLEC13A (C-type lectin domain family 13 member A), also known as C-type lectin receptor DCL-1, is a type I transmembrane C-type lectin DCL-1/CD302. DCL-1 protein was highly conserved among the human, mouse, and rat...
TMPY-03349 CD302 Protein, Rat, Recombinant (His) Rat HEK293
CD302/CLEC13A (C-type lectin domain family 13 member A), also known as C-type lectin receptor DCL-1, is a type I transmembrane C-type lectin DCL-1/CD302. DCL-1 protein was highly conserved among the human, mouse, and rat...
TMPH-02526 Arginase-2/ARG2 Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synth...
TMPJ-00796 Serpin E2 Protein, Human, Recombinant (His) Human Human Cells
Serpin E2 is a secreted protein that belongs to the serpin family. Serpin E2 is a serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Serpin E2 expression is weak or absent in all normal panc...
TMPH-02322 SLC30A10 Protein, Human, Recombinant (His & Myc) Human E. coli
Plays a pivotal role in manganese transport. Manganese is an essential cation for the function of several enzymes, including some crucially important for the metabolism of neurotransmitters and other neuronal metabolic p...
TMPH-03281 PRKN Protein, Rat, Recombinant (His & Myc) Rat Baculovirus
Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Substrates include SYT11 and VDAC1. Other substrates are BCL2, CCNE1, GPR37, ...
------------------------ More ------------------------
RAGE Protein, Human, Recombinant
TMPY-02881
Species: Human
Expression System: HEK293
RAGE Protein, Human, Recombinant (His)
TMPY-02927
Species: Human
Expression System: HEK293
E-Cadherin/Cadherin-1 Protein, Human, Recombinant (hFc)
TMPY-03762
Species: Human
Expression System: HEK293
CD131 Protein, Human, Recombinant (His)
TMPY-01650
Species: Human
Expression System: HEK293
Leptin Receptor Protein, Human, Recombinant (His)
TMPY-01725
Species: Human
Expression System: HEK293
Ficolin 1/FCN1 Protein, Human, Recombinant (His)
TMPY-01028
Species: Human
Expression System: HEK293
IL-7R alpha/CD127 Protein, Human, Recombinant (His)
TMPY-01209
Species: Human
Expression System: HEK293
IL-7R alpha/CD127 Protein, Cynomolgus, Recombinant (His)
TMPY-00635
Species: Cynomolgus
Expression System: HEK293
FSTL3 Protein, Human, Recombinant (His)
TMPK-00751
Species: Human
Expression System: HEK293
CISD1 Protein, Human, Recombinant (His)
TMPY-03227
Species: Human
Expression System: E. coli
Serpin E2 Protein, Mouse, Recombinant (His)
TMPJ-01083
Species: Mouse
Expression System: Human Cells
SBDS Protein, Human, Recombinant (His)
TMPY-00518
Species: Human
Expression System: E. coli
CEL Protein, Mouse, Recombinant (His)
TMPY-03353
Species: Mouse
Expression System: Baculovirus-Insect Cells
SBDS Protein, Mouse, Recombinant (His)
TMPY-00452
Species: Mouse
Expression System: E. coli
TPK1 Protein, Human, Recombinant (His)
TMPY-04773
Species: Human
Expression System: E. coli
Zaire ebolavirus (strain Kikwit-95) VP40 Protein (His & Myc)
TMPH-03728
Species: ZEBOV
Expression System: Baculovirus
Zaire ebolavirus (strain Kikwit-95) VP40 Protein (His)
TMPH-03727
Species: ZEBOV
Expression System: E. coli
ECE1 Protein, Human, Recombinant (His)
TMPY-01929
Species: Human
Expression System: HEK293
SGSH Protein, Human, Recombinant (His)
TMPJ-01002
Species: Human
Expression System: Human Cells
TMEM106B Protein, Mouse, Recombinant (hFc)
TMPK-01069
Species: Mouse
Expression System: HEK293
ACADM Protein, Human, Recombinant (His)
TMPJ-00834
Species: Human
Expression System: E. coli
Claudin-11 Protein, Human, Recombinant (mFc)
TMPY-03175
Species: Human
Expression System: HEK293
Neurofascin Protein, Human, Recombinant (hFc)
TMPY-04620
Species: Human
Expression System: HEK293
TIM-1/KIM-1/HAVCR1 Protein, Rat, Recombinant (His)
TMPY-01455
Species: Rat
Expression System: HEK293
TIM-1/KIM-1/HAVCR1 Protein, Human, Recombinant (His)
TMPY-01768
Species: Human
Expression System: HEK293
TIM-1/KIM-1/HAVCR1 Protein, Canine, Recombinant (mFc)
TMPY-04280
Species: Canine
Expression System: HEK293
TIM-1/KIM-1/HAVCR1 Protein, Rat, Recombinant (His & hFc)
TMPY-01317
Species: Rat
Expression System: HEK293
TIM-1/KIM-1/HAVCR1 Protein, Rhesus, Recombinant (His)
TMPY-01671
Species: Rhesus
Expression System: HEK293
TIM-1/KIM-1/HAVCR1 Protein, Human, Recombinant (His & hFc)
TMPY-01161
Species: Human
Expression System: HEK293
Neurofascin Protein, Human, Recombinant (His)
TMPY-03797
Species: Human
Expression System: HEK293
IMPA1 Protein, Human, Recombinant (His)
TMPY-02394
Species: Human
Expression System: E. coli
Neurofascin Protein, Human, Recombinant (hFc), Biotinylated
TMPY-05268
Species: Human
Expression System: HEK293
Aldolase B Protein, Human, Recombinant (GST)
TMPY-02622
Species: Human
Expression System: E. coli
SFTPB Protein, Human, Recombinant (His)
TMPY-06810
Species: Human
Expression System: CHO
TIM Protein, Human, Recombinant (His)
TMPJ-01034
Species: Human
Expression System: E. coli
TIM-1/KIM-1/HAVCR1 Protein, Mouse, Recombinant (His & hFc)
TMPY-01244
Species: Mouse
Expression System: HEK293
TIM-1/KIM-1/HAVCR1 Protein, Canine, Recombinant (His)
TMPY-01350
Species: Canine
Expression System: HEK293
TIM-1/KIM-1/HAVCR1 Protein, Human, Recombinant (aa 1-135, His)
TMPY-01173
Species: Human
Expression System: HEK293
TIM-1/KIM-1/HAVCR1 Protein, Rhesus, Recombinant
TMPY-01951
Species: Rhesus
Expression System: HEK293
Beta-amyloid 39/Beta-APP39 Protein, Human, Recombinant (aa 672-710, His & GST)
TMPY-03884
Species: Human
Expression System: E. coli
Beta-amyloid 38/Beta-APP38 Protein, Human, Recombinant (aa 672-709, His & GST)
TMPY-03885
Species: Human
Expression System: E. coli
Beta-amyloid 40/Beta-APP40 Protein, Human, Recombinant (His & GST)
TMPY-02110
Species: Human
Expression System: E. coli
Beta-amyloid 42/Beta-APP42 Protein, Human, Recombinant (His & GST)
TMPY-02221
Species: Human
Expression System: E. coli
CD302 Protein, Mouse, Recombinant (hFc)
TMPY-02406
Species: Mouse
Expression System: HEK293
CD302 Protein, Mouse, Recombinant (His)
TMPY-02407
Species: Mouse
Expression System: HEK293
CD302 Protein, Rat, Recombinant (His)
TMPY-03349
Species: Rat
Expression System: HEK293
Arginase-2/ARG2 Protein, Mouse, Recombinant (His & SUMO)
TMPH-02526
Species: Mouse
Expression System: E. coli
Serpin E2 Protein, Human, Recombinant (His)
TMPJ-00796
Species: Human
Expression System: Human Cells
SLC30A10 Protein, Human, Recombinant (His & Myc)
TMPH-02322
Species: Human
Expression System: E. coli
PRKN Protein, Rat, Recombinant (His & Myc)
TMPH-03281
Species: Rat
Expression System: Baculovirus
Cat No. Product Name
L1120 AMPK-Targeted Compound Library

80 compounds
80 well-chosen unique AMPK-targeted small molecules;
L8200 Anti-Aging Compound Library

3324 compounds
A unique collection of 3324 anti-aging compounds for high throughput screening (HTS) and high content screening (HCS);
L5510 Drug-induced Liver Injury (DILI) Compound Library

1040 compounds
A unique collection of 1040 hepatotoxicity causing compounds, a powerful tool for drug toxicity study, can be used for HTS and HCS screening;
L9840 Anti-Alzheimer's Disease Compound Library

1040 compounds
A unique collection of 1040 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS.
TargetMol