Home Tools
Log in
Cart

Reactive Oxygen Species

Reactive oxygen species (ROS), such as superoxide anion (O2-), hydrogen peroxide (H2O2), and hydroxyl radical (HO•), consist of radical and non-radical oxygen species formed by the partial reduction of oxygen. Cellular ROS are generated endogenously during mitochondrial oxidative metabolism as well as in cellular response to xenobiotics, cytokines, and bacterial invasion. ROS also activates MAPK pathways by the direct inhibition of MAPK phosphatases. Through PTEN, the PI3K pathway is subject to reversible redox regulation by ROS generated by growth factor stimulation. The activation of autophagy may be a cellular defense mechanism in response to ROS.
Cat. No. Product name CAS No. Purity Chemical Structure
T67927 BAY-069 2639638-66-5 98%
BAY-069 is an inhibitor. BAY-069 inhibited branched-chain amino acid transaminase 1 (BCAT1) at IC50:31 nM and branched-chain amino acid transaminase 2 (BCAT2) at...
T8306 Epiberberine chloride 889665-86-5 98%
Epiberberine chloride is an alkaloid isolated from Coptis chinensis, acts as a potent AChE and BChE inhibitor, and a non-competitive BACE1 inhibitor (IC50s: 1.07...
T63918 α-Tocopherol phosphate disodium 60934-46-5 98%
α-Tocopherol phosphate disodium shows potent antioxidant properties. α-Tocopherol phosphate disodium protects against long-wave UVA1-induced cell death. α-Tocoph...
T41242 Uric acid sodium 1198-77-2 98%
Uric acid sodium, scavengers of oxygen radicals, is a potent and common antioxidant that helps maintain stable blood pressure and resist oxidative stress. Uric a...
TN1058 Pelargonidin chloride 134-04-3 98%
Pelargonidin chloride shows protective effect against CTN-induced oxidative stress in HepG2 cells and up-regulated the activity of detoxification enzyme levels t...
T4902 ISOQUERCITRIN 21637-25-2 98%
Isoquercitrin is an effective antioxidant and an eosinophilic inflammation suppressor.
T12059L Mitoquinone mesylate 845959-50-4 98%
Mitoquinone mesylate is a TPP-based, mitochondrially targeted antioxidant to protect against oxidative damage.
T38155 N-Acetyl-D-cysteine 26117-28-2 98%
N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group, but cannot enter the glutathione metabolic pathway[1]...
T17155 Trabectedin 114899-77-3 98%
Trabectedin a tetrahydroisoquinoline alkaloid. Trabectedin binds to the minor groove of DNA, blocks transcription of stress-induced proteins, induces DNA backbon...
TN1403 Arjunolic acid 465-00-9 98%
Arjunolic acid has antioxidant, anti-inflammatory, antinociceptive and anticholinesterasic (AChE and BuChE) activities, it may as promising targets for the devel...
T16747 Riboflavin Tetrabutyrate 752-56-7 98%
Riboflavin Tetrabutyrate is a lipophilic flavin derivative. Riboflavin Tetrabutyrate has antioxidative and lipid peroxide-removing activity.
T5852 Canthaxanthin 514-78-3 98%
Canthaxanthin is a red-orange carotenoid that belongs to the xanthophyll group. This naturally occurring pigment is present in bacteria, algae and some fungi.
T11580 Heme Oxygenase-1-IN-1 1093058-52-6 98%
HO-1-IN-1 is a heme oxygenase 1 (HO-1) inhibitor (IC50: 250 nM).
T37688 Cyfluthrin 68359-37-5 98%
Cyfluthrin is a pyrethroid insecticide and a modulator of voltage-gated sodium channels (Nav).1,2It slowly activates rat recombinant Nav1.8 channels, delays inac...
T10492 BD-AcAc 2 1208313-97-6 98%
BD-AcAc 2 is a ketone monoester and can be used as a source of oral nutritional ketones. BD-AcAc 2 can elevate plasma levels of acetoacetate and β-hydroxybutyrat...
TN7108 Urolithin C 165393-06-6 98%
Urolithin C is a gut metabolite of ellagic acid. Urolithin C induces apoptosis in PC12 cells through a mitochondria-mediated pathway.
T20578 Maclurin 519-34-6 98%
Maclurin is a phenolic component of mulberry twigs, exerts anti-metastatic effects. Maclurin effectively protects against OH-induced damages to DNA and MSCs and ...
T36404L PRLX-93936 HCL 1094210-96-4 98%
PRLX-93936 hcl is an analog of erastin and demonstrated synergistic effects against non-small cell lung cancer (NSCLC) cells with cisplatin.
T7703 PK11007 874146-69-7
PK11007 is an anti-p53 drug.
T8193 α-Thujone 546-80-5
Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.
BAY-069
T67927
BAY-069 is an inhibitor. BAY-069 inhibited branched-chain amino acid transaminase 1 (BCAT1) at IC50:31 nM and branched-chain amino acid transaminase 2 (BCAT2) at...
Epiberberine chloride
T8306
Epiberberine chloride is an alkaloid isolated from Coptis chinensis, acts as a potent AChE and BChE inhibitor, and a non-competitive BACE1 inhibitor (IC50s: 1.07...
α-Tocopherol phosphate disodium
T63918
α-Tocopherol phosphate disodium shows potent antioxidant properties. α-Tocopherol phosphate disodium protects against long-wave UVA1-induced cell death. α-Tocoph...
Uric acid sodium
T41242
Uric acid sodium, scavengers of oxygen radicals, is a potent and common antioxidant that helps maintain stable blood pressure and resist oxidative stress. Uric a...
Pelargonidin chloride
TN1058
Pelargonidin chloride shows protective effect against CTN-induced oxidative stress in HepG2 cells and up-regulated the activity of detoxification enzyme levels t...
ISOQUERCITRIN
T4902
Isoquercitrin is an effective antioxidant and an eosinophilic inflammation suppressor.
Mitoquinone mesylate
T12059L
Mitoquinone mesylate is a TPP-based, mitochondrially targeted antioxidant to protect against oxidative damage.
N-Acetyl-D-cysteine
T38155
N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group, but cannot enter the glutathione metabolic pathway[1]...
Trabectedin
T17155
Trabectedin a tetrahydroisoquinoline alkaloid. Trabectedin binds to the minor groove of DNA, blocks transcription of stress-induced proteins, induces DNA backbon...
Arjunolic acid
TN1403
Arjunolic acid has antioxidant, anti-inflammatory, antinociceptive and anticholinesterasic (AChE and BuChE) activities, it may as promising targets for the devel...
Riboflavin Tetrabutyrate
T16747
Riboflavin Tetrabutyrate is a lipophilic flavin derivative. Riboflavin Tetrabutyrate has antioxidative and lipid peroxide-removing activity.
Canthaxanthin
T5852
Canthaxanthin is a red-orange carotenoid that belongs to the xanthophyll group. This naturally occurring pigment is present in bacteria, algae and some fungi.
Heme Oxygenase-1-IN-1
T11580
HO-1-IN-1 is a heme oxygenase 1 (HO-1) inhibitor (IC50: 250 nM).
Cyfluthrin
T37688
Cyfluthrin is a pyrethroid insecticide and a modulator of voltage-gated sodium channels (Nav).1,2It slowly activates rat recombinant Nav1.8 channels, delays inac...
BD-AcAc 2
T10492
BD-AcAc 2 is a ketone monoester and can be used as a source of oral nutritional ketones. BD-AcAc 2 can elevate plasma levels of acetoacetate and β-hydroxybutyrat...
Urolithin C
TN7108
Urolithin C is a gut metabolite of ellagic acid. Urolithin C induces apoptosis in PC12 cells through a mitochondria-mediated pathway.
Maclurin
T20578
Maclurin is a phenolic component of mulberry twigs, exerts anti-metastatic effects. Maclurin effectively protects against OH-induced damages to DNA and MSCs and ...
PRLX-93936 HCL
T36404L
PRLX-93936 hcl is an analog of erastin and demonstrated synergistic effects against non-small cell lung cancer (NSCLC) cells with cisplatin.
PK11007
T7703
PK11007 is an anti-p53 drug.
α-Thujone
T8193
Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.
1 2 3 4 5 6 7 8 9 10