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Inhibitors Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling
MAPK Membrane transporter/Ion channel Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome Stem Cells Tyrosine Kinase/Adaptors Ubiquitination Others
Compound Libraries Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD Drug-like Compound Libraries Fragment Libraries Custom Compound Library
Signaling Pathways Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling
DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK Membrane transporter/Ion channel
Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome
Stem Cells Tyrosine Kinase/Adaptors Ubiquitination
Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries
Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD
Drug-like Compound Libraries Compound Libraries for HTS/HCS
Fragment Libraries General Fragment Libraries Characteristic Fragment Libraries Custom Compound Library

Microtubule Associated

Microtubule-associated proteins (MAPs) are proteins that interact with the microtubules of the cellular cytoskeleton. MAPs bind to the tubulin subunits that make up microtubules to regulate their stability. A large variety of MAPs have been identified in many different cell types, and they have been found to carry out a wide range of functions. These include both stabilizing and destabilizing microtubules, guiding microtubules towards specific cellular locations, cross-linking microtubules and mediating the interactions of microtubules with other proteins in the cell.
Cat. No. Product name CAS No. Purity Chemical Structure
T6722 Vinflunine Tartrate 1201898-17-0 98%
Vinflunine Tartrat is a vinca alkaloid uniquely fluorinated with the properties of mitotic-arresting and tubulin-interacting activity.
T12823 S516 1016543-77-3 98%
S516 is an active CKD-516 metabolite and is a potent inhibitor of tubulin polymerization(IC50 of 4.29 μM), has marked antitumor activity.
T17229 Verubulin 827031-83-4 98%
Verubulin is a microtubule-disrupting agent with potent and broad-spectrum in vitro and in vivo cytotoxic activities.
T16543 Pironetin 151519-02-7 98%
Pironetin binds to α-tubulin and is an effective inhibitor of microtubule polymerization. It also has cell cycle arrest and antitumor activity. Pironetin is an α...
T16387 Ombrabulin 181816-48-8 98%
Ombrabulin is a derivative of CA-4 phosphate. It is known to show antivascular effects through selective disruption of the tubulin cytoskeleton of endothelial ce...
T10428 AZ82 1449578-65-7 98%
AZ82 is a selective kinesin-like protein KIFC1 (HSET/KIFC1) inhibitor (Ki: 43 nM; IC50: 300 nM for KIFC1).
T16386 Ombrabulin hydrochloride 253426-24-3 98%
Ombrabulin hydrochloride is a derivative of CA-4 phosphate. It is known to show antivascular effects through selective disruption of the tubulin cytoskeleton of ...
TQ0202 Epothilone D 189453-10-9 98%
Epothilone D (KOS 862) is an effective microtubule stabilizer.
T6721 Vinblastine 865-21-4 98%
Vinblastine inhibits microtubule formation and suppresses nAChR activity with IC50 of 8.9 μM, used to treat certain kinds of cancer.
T12052 Mivobulin 122332-18-7 98%
Mivobulin is an inhibitor of tubulin .
T13226 Tubulin inhibitor 8 1309925-39-0 98%
Tubulin inhibitor 8 is an inhibitor of tubulin and multiple cancer cell lines (tubulin polymerization with an IC50 of 0.73 μM, K562 cell growth with an IC50 of 1...
T10704 CCB02 2100864-57-9 98%
CCB02 is a selective CPAP-tubulin interaction inhibitor (IC50: 689 nM) with anti-tumor activity. CCB02 shows no inhibition on the cell cycle- and centrosome-rela...
T13807 OSIP-486823 200803-37-8 98%
OSIP-486823 is a microtubule-interfering agent with distinct biological effects on both protein kinase G (PKG) and microtubules.
T13228 Tubulysin D 309935-57-7 98%
Tubulysin D is a tetrapeptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis, and displays potent antitumor activity.
T13227 Tubulin inhibitor 1 2237054-53-2 98%
Tubulin inhibitor 1 is an inhibitor of tubulin, inhibits tubulin polymerization, with potent anti-tumor activity, induces cellular apoptosis causes and cellular ...
T16997 Tasidotin hydrochloride 623174-20-9 98%
Tasidotin hydrochloride is a peptide analog of the antimitotic depsipeptide dolastatin 15. Tasidotin hydrochloride is an inhibitor of microtubule assembly and mi...
T12805 S-methyl DM1 912569-84-7 98%
S-methyl DM1 is a thiomethyl derivative of Maytansine. S-methyl DM1 binds to tubulin(Kd of 0.93 μM) and inhibts microtubule polymerization.
T13225 Tubulin inhibitor 7 1309925-41-4 98%
Tubulin inhibitor 7 is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines (tubulin polymerization (IC50: 0.52 μM), K562 cell growth (IC...
TQ0141 Taltobulin 228266-40-8 98%
Taltobulin (HTI-286) is a potent tubulin inhibitor.
T22262 Ansamitocin p-3 66584-72-3 98%
Ansamitocin p-3 is an inhibitor of microtubule with IC50 of 3.4 μM for tubulin polymerization.
Vinflunine Tartrate
T6722
Vinflunine Tartrat is a vinca alkaloid uniquely fluorinated with the properties of mitotic-arresting and tubulin-interacting activity.
S516
T12823
S516 is an active CKD-516 metabolite and is a potent inhibitor of tubulin polymerization(IC50 of 4.29 μM), has marked antitumor activity.
Verubulin
T17229
Verubulin is a microtubule-disrupting agent with potent and broad-spectrum in vitro and in vivo cytotoxic activities.
Pironetin
T16543
Pironetin binds to α-tubulin and is an effective inhibitor of microtubule polymerization. It also has cell cycle arrest and antitumor activity. Pironetin is an α...
Ombrabulin
T16387
Ombrabulin is a derivative of CA-4 phosphate. It is known to show antivascular effects through selective disruption of the tubulin cytoskeleton of endothelial ce...
AZ82
T10428
AZ82 is a selective kinesin-like protein KIFC1 (HSET/KIFC1) inhibitor (Ki: 43 nM; IC50: 300 nM for KIFC1).
Ombrabulin hydrochloride
T16386
Ombrabulin hydrochloride is a derivative of CA-4 phosphate. It is known to show antivascular effects through selective disruption of the tubulin cytoskeleton of ...
Epothilone D
TQ0202
Epothilone D (KOS 862) is an effective microtubule stabilizer.
Vinblastine
T6721
Vinblastine inhibits microtubule formation and suppresses nAChR activity with IC50 of 8.9 μM, used to treat certain kinds of cancer.
Mivobulin
T12052
Mivobulin is an inhibitor of tubulin .
Tubulin inhibitor 8
T13226
Tubulin inhibitor 8 is an inhibitor of tubulin and multiple cancer cell lines (tubulin polymerization with an IC50 of 0.73 μM, K562 cell growth with an IC50 of 1...
CCB02
T10704
CCB02 is a selective CPAP-tubulin interaction inhibitor (IC50: 689 nM) with anti-tumor activity. CCB02 shows no inhibition on the cell cycle- and centrosome-rela...
OSIP-486823
T13807
OSIP-486823 is a microtubule-interfering agent with distinct biological effects on both protein kinase G (PKG) and microtubules.
Tubulysin D
T13228
Tubulysin D is a tetrapeptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis, and displays potent antitumor activity.
Tubulin inhibitor 1
T13227
Tubulin inhibitor 1 is an inhibitor of tubulin, inhibits tubulin polymerization, with potent anti-tumor activity, induces cellular apoptosis causes and cellular ...
Tasidotin hydrochloride
T16997
Tasidotin hydrochloride is a peptide analog of the antimitotic depsipeptide dolastatin 15. Tasidotin hydrochloride is an inhibitor of microtubule assembly and mi...
S-methyl DM1
T12805
S-methyl DM1 is a thiomethyl derivative of Maytansine. S-methyl DM1 binds to tubulin(Kd of 0.93 μM) and inhibts microtubule polymerization.
Tubulin inhibitor 7
T13225
Tubulin inhibitor 7 is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines (tubulin polymerization (IC50: 0.52 μM), K562 cell growth (IC...
Taltobulin
TQ0141
Taltobulin (HTI-286) is a potent tubulin inhibitor.
Ansamitocin p-3
T22262
Ansamitocin p-3 is an inhibitor of microtubule with IC50 of 3.4 μM for tubulin polymerization.
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