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Microtubule Associated

Microtubule-associated proteins (MAPs) are proteins that interact with the microtubules of the cellular cytoskeleton. MAPs bind to the tubulin subunits that make up microtubules to regulate their stability. A large variety of MAPs have been identified in many different cell types, and they have been found to carry out a wide range of functions. These include both stabilizing and destabilizing microtubules, guiding microtubules towards specific cellular locations, cross-linking microtubules and mediating the interactions of microtubules with other proteins in the cell.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T36848 Combretastatin A-1 109971-63-3 97.49%
Combretastatin A-1
Combretastatin A-1 is a potent microtubule inhibitor with anti-tumour and anti-vascular activity, acting through microtubule protein depolymerisation-mediated in...
T16997 Tasidotin hydrochloride 623174-20-9 98%
Tasidotin hydrochloride
Tasidotin hydrochloride is a peptide analog of the antimitotic depsipeptide dolastatin 15. Tasidotin hydrochloride is an inhibitor of microtubule assembly and mi...
T17229 Verubulin 827031-83-4 98%
Verubulin
Verubulin is a microtubule-disrupting agent with potent and broad-spectrum in vitro and in vivo cytotoxic activities.
T6721 Vinblastine 865-21-4 98%
Vinblastine
Vinblastine inhibits microtubule formation and suppresses nAChR activity with IC50 of 8.9 μM, used to treat certain kinds of cancer.
TQ0112 Tubulysin A 205304-86-5 98%
Tubulysin A
Tubulysin A is a natural product from myxobacterial. It has many function in vitro assays, including anti-microtubule, anti-mitotic, an apoptosis inducer, antica...
T13227 Tubulin inhibitor 1 2237054-53-2 98%
Tubulin inhibitor 1
Tubulin inhibitor 1 is an inhibitor of tubulin, inhibits tubulin polymerization, with potent anti-tumor activity, induces cellular apoptosis causes and cellular ...
T10428 AZ82 1449578-65-7 98%
AZ82
AZ82 is a selective kinesin-like protein KIFC1 (HSET/KIFC1) inhibitor (Ki: 43 nM; IC50: 300 nM for KIFC1).
T10704 CCB02 2100864-57-9 98%
CCB02
CCB02 is a selective CPAP-tubulin interaction inhibitor (IC50: 689 nM) with anti-tumor activity. CCB02 shows no inhibition on the cell cycle- and centrosome-rela...
T11712 Jasplakinolide 102396-24-7 98%
Jasplakinolide
Jasplakinolide(Jaspamide), a naturally occurring cyclic peptide from marine sponges, is a potent inducer of actin polymerization.Jasplakinolide exhibits antifung...
T12805 S-methyl DM1 912569-84-7 98%
S-methyl DM1
S-methyl DM1 is a thiomethyl derivative of Maytansine. S-methyl DM1 binds to tubulin(Kd of 0.93 μM) and inhibts microtubule polymerization.
T12052 Mivobulin 122332-18-7 98%
Mivobulin
Mivobulin is an inhibitor of tubulin .
T13901 SS28 141172-08-9 98%
SS28
SS28 inhibits tubulin polymerization to cause cell cycle arrest at G2/M phase.
T16543 Pironetin 151519-02-7 98%
Pironetin
Pironetin binds to α-tubulin and is an effective inhibitor of microtubule polymerization. It also has cell cycle arrest and antitumor activity. Pironetin is an α...
T6722 Vinflunine Tartrate 1201898-17-0 98%
Vinflunine Tartrate
Vinflunine Tartrate, a uniquely fluorinated vinca alkaloid, exhibits mitotic-arresting and tubulin-interacting properties.
T16387 Ombrabulin 181816-48-8 98%
Ombrabulin
Ombrabulin is a derivative of CA-4 phosphate. It is known to show antivascular effects through selective disruption of the tubulin cytoskeleton of endothelial ce...
T12823 S516 1016543-77-3 98%
S516
S516 is an active CKD-516 metabolite and is a potent inhibitor of tubulin polymerization(IC50 of 4.29 μM), has marked antitumor activity.
TQ0202 Epothilone D 189453-10-9 98%
Epothilone D
Epothilone D (KOS 862) is an effective microtubule stabilizer.
T16386 Ombrabulin hydrochloride 253426-24-3 98%
Ombrabulin hydrochloride
Ombrabulin hydrochloride is a synthetic, selective CA-4 phosphate ester or derivative of Ombrabulin to disrupt the tubulin cytoskeleton of endothelial cells and ...
T13225 Tubulin inhibitor 7 1309925-41-4 98%
Tubulin inhibitor 7
Tubulin inhibitor 7 is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines (tubulin polymerization (IC50: 0.52 μM), K562 cell growth (IC...
TQ0141 Taltobulin 228266-40-8 98%
Taltobulin
Taltobulin (HTI-286) is a potent tubulin inhibitor.
Combretastatin A-1
T36848
Combretastatin A-1 is a potent microtubule inhibitor with anti-tumour and anti-vascular activity, acting through microtubule protein depolymerisation-mediated in...
Tasidotin hydrochloride
T16997
Tasidotin hydrochloride is a peptide analog of the antimitotic depsipeptide dolastatin 15. Tasidotin hydrochloride is an inhibitor of microtubule assembly and mi...
Verubulin
T17229
Verubulin is a microtubule-disrupting agent with potent and broad-spectrum in vitro and in vivo cytotoxic activities.
Vinblastine
T6721
Vinblastine inhibits microtubule formation and suppresses nAChR activity with IC50 of 8.9 μM, used to treat certain kinds of cancer.
Tubulysin A
TQ0112
Tubulysin A is a natural product from myxobacterial. It has many function in vitro assays, including anti-microtubule, anti-mitotic, an apoptosis inducer, antica...
Tubulin inhibitor 1
T13227
Tubulin inhibitor 1 is an inhibitor of tubulin, inhibits tubulin polymerization, with potent anti-tumor activity, induces cellular apoptosis causes and cellular ...
AZ82
T10428
AZ82 is a selective kinesin-like protein KIFC1 (HSET/KIFC1) inhibitor (Ki: 43 nM; IC50: 300 nM for KIFC1).
CCB02
T10704
CCB02 is a selective CPAP-tubulin interaction inhibitor (IC50: 689 nM) with anti-tumor activity. CCB02 shows no inhibition on the cell cycle- and centrosome-rela...
Jasplakinolide
T11712
Jasplakinolide(Jaspamide), a naturally occurring cyclic peptide from marine sponges, is a potent inducer of actin polymerization.Jasplakinolide exhibits antifung...
S-methyl DM1
T12805
S-methyl DM1 is a thiomethyl derivative of Maytansine. S-methyl DM1 binds to tubulin(Kd of 0.93 μM) and inhibts microtubule polymerization.
Mivobulin
T12052
Mivobulin is an inhibitor of tubulin .
SS28
T13901
SS28 inhibits tubulin polymerization to cause cell cycle arrest at G2/M phase.
Pironetin
T16543
Pironetin binds to α-tubulin and is an effective inhibitor of microtubule polymerization. It also has cell cycle arrest and antitumor activity. Pironetin is an α...
Vinflunine Tartrate
T6722
Vinflunine Tartrate, a uniquely fluorinated vinca alkaloid, exhibits mitotic-arresting and tubulin-interacting properties.
Ombrabulin
T16387
Ombrabulin is a derivative of CA-4 phosphate. It is known to show antivascular effects through selective disruption of the tubulin cytoskeleton of endothelial ce...
S516
T12823
S516 is an active CKD-516 metabolite and is a potent inhibitor of tubulin polymerization(IC50 of 4.29 μM), has marked antitumor activity.
Epothilone D
TQ0202
Epothilone D (KOS 862) is an effective microtubule stabilizer.
Ombrabulin hydrochloride
T16386
Ombrabulin hydrochloride is a synthetic, selective CA-4 phosphate ester or derivative of Ombrabulin to disrupt the tubulin cytoskeleton of endothelial cells and ...
Tubulin inhibitor 7
T13225
Tubulin inhibitor 7 is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines (tubulin polymerization (IC50: 0.52 μM), K562 cell growth (IC...
Taltobulin
TQ0141
Taltobulin (HTI-286) is a potent tubulin inhibitor.
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TargetMol