Microtubule Associated

Microtubule-associated proteins (MAPs) are proteins that interact with the microtubules of the cellular cytoskeleton. MAPs bind to the tubulin subunits that make up microtubules to regulate their stability. A large variety of MAPs have been identified in many different cell types, and they have been found to carry out a wide range of functions. These include both stabilizing and destabilizing microtubules, guiding microtubules towards specific cellular locations, cross-linking microtubules and mediating the interactions of microtubules with other proteins in the cell.

Cat. No.	Product name	CAS No.	Purity
T16997	Tasidotin hydrochloride	623174-20-9	98%
T16997	Tasidotin hydrochloride is a peptide analog of the antimitotic depsipeptide dolastatin 15. Tasidotin hydrochloride is an inhibitor of microtubule assembly and mi...
T17229	Verubulin	827031-83-4	98%
T17229	Verubulin is a microtubule-disrupting agent with potent and broad-spectrum in vitro and in vivo cytotoxic activities.
T6721	Vinblastine	865-21-4	98%
T6721	Vinblastine inhibits microtubule formation and suppresses nAChR activity with IC50 of 8.9 μM, used to treat certain kinds of cancer.
TQ0112	Tubulysin A	205304-86-5	98%
TQ0112	Tubulysin A is a natural product from myxobacterial. It has many function in vitro assays, including anti-microtubule, anti-mitotic, an apoptosis inducer, antica...
T13807	OSIP-486823	200803-37-8	98%
T13807	OSIP-486823 is a microtubule-interfering agent with distinct biological effects on both protein kinase G (PKG) and microtubules.
T13227	Tubulin inhibitor 1	2237054-53-2	98%
T13227	Tubulin inhibitor 1 is an inhibitor of tubulin, inhibits tubulin polymerization, with potent anti-tumor activity, induces cellular apoptosis causes and cellular ...
T10428	AZ82	1449578-65-7	98%
T10428	AZ82 is a selective kinesin-like protein KIFC1 (HSET/KIFC1) inhibitor (Ki: 43 nM; IC50: 300 nM for KIFC1).
T10704	CCB02	2100864-57-9	98%
T10704	CCB02 is a selective CPAP-tubulin interaction inhibitor (IC50: 689 nM) with anti-tumor activity. CCB02 shows no inhibition on the cell cycle- and centrosome-rela...
T11712	Jasplakinolide	102396-24-7	98%
T11712	Jasplakinolide(Jaspamide), a naturally occurring cyclic peptide from marine sponges, is a potent inducer of actin polymerization.Jasplakinolide exhibits antifung...
T12805	S-methyl DM1	912569-84-7	98%
T12805	S-methyl DM1 is a thiomethyl derivative of Maytansine. S-methyl DM1 binds to tubulin(Kd of 0.93 μM) and inhibts microtubule polymerization.
T12052	Mivobulin	122332-18-7	98%
T12052	Mivobulin is an inhibitor of tubulin .
T13901	SS28	141172-08-9	98%
T13901	SS28 inhibits tubulin polymerization to cause cell cycle arrest at G2/M phase.
T16543	Pironetin	151519-02-7	98%
T16543	Pironetin binds to α-tubulin and is an effective inhibitor of microtubule polymerization. It also has cell cycle arrest and antitumor activity. Pironetin is an α...
T6722	Vinflunine Tartrate	1201898-17-0	98%
T6722	Vinflunine Tartrat is a vinca alkaloid uniquely fluorinated with the properties of mitotic-arresting and tubulin-interacting activity.
T16387	Ombrabulin	181816-48-8	98%
T16387	Ombrabulin is a derivative of CA-4 phosphate. It is known to show antivascular effects through selective disruption of the tubulin cytoskeleton of endothelial ce...
T12823	S516	1016543-77-3	98%
T12823	S516 is an active CKD-516 metabolite and is a potent inhibitor of tubulin polymerization(IC50 of 4.29 μM), has marked antitumor activity.
TQ0202	Epothilone D	189453-10-9	98%
TQ0202	Epothilone D (KOS 862) is an effective microtubule stabilizer.
T16386	Ombrabulin hydrochloride	253426-24-3	98%
T16386	Ombrabulin hydrochloride is a synthetic, selective CA-4 phosphate ester or derivative of Ombrabulin to disrupt the tubulin cytoskeleton of endothelial cells and ...
T13225	Tubulin inhibitor 7	1309925-41-4	98%
T13225	Tubulin inhibitor 7 is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines (tubulin polymerization (IC50: 0.52 μM), K562 cell growth (IC...
TQ0141	Taltobulin	228266-40-8	98%
TQ0141	Taltobulin (HTI-286) is a potent tubulin inhibitor.