T4480 |
Vardenafil dihydrochloride
|
224789-15-5
|
99.77%
|
|
Vardenafil dihydrochloride (Levitra) is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively.
|
TN2217 |
Sophoflavescenol
|
216450-65-6
|
99.65%
|
|
Sophoflavescenol is a mixed inhibitor of PDE5 with a K(i) value of 0.005 microM. Sophoflavescenol has antioxidant, anti-inflammatory, and apoptotic effects , the...
|
T19706 |
Ro 20-1724
|
29925-17-5
|
98.82%
|
|
Ro 20-1724 (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1 μ...
|
T12315 |
OR-1896
|
220246-81-1
|
98%
|
|
OR-1896 is an active long-lived Levosimendan metabolite, is a highly selective inhibitor of phosphodiesterase (PDE) III isoformand a powerful vasodilator.
|
T22491 |
PDE7-IN-2
|
107522-19-0
|
98%
|
|
PDE7-IN-2 is an inhibitor of phosphodiesterase 7 (IC50 = 2.1 µM) and can be used in Parkinson's disease studies.
|
T10994 |
Deltasonamide 2
|
2088485-34-9
|
98%
|
|
Deltasonamide 2 is a competitive, high affinity PDEδ inhibitor with a Kd of ~385 pM.
|
T12394 |
PDE5-IN-2
|
2244517-61-9
|
98%
|
|
PDE5-IN-2 is a potent, highly selective, and orally active inhibitor of PDE5(IC50 of 0.31 nM)
|
T16484 |
PF-05180999
|
1394033-54-5
|
98%
|
|
PF-05180999 is an inhibitor of phosphodiesterase 2A (IC50: 1.6 nM).
|
TN2095 |
Pomiferin
|
572-03-2
|
98%
|
|
Pomiferin is a natural product inhibitor of carbonic anhydrase I and II isoenzymes. It has anticancer, antibacterial and antidiabetic properties. Pomiferin has a...
|
T16434 |
PAT-048
|
1359983-15-5
|
98%
|
|
PAT-048 is an effective and selective autotaxin inhibitor. PAT-048 reduces dermal fibrosis in vivo. PAT-048 also inhibits IL-6 mRNA expression but displays no ef...
|
TN2974 |
3-O-Methylquercetin tetraacetate
|
1486-69-7
|
98%
|
|
Quercetin 3-O-methyl ether is a potent phosphodiesterase (PDE)3/4 inhibitor, it has potential for treating asthma against ovalbumin-induced airway hyperresponsiv...
|
T10994L |
Deltasonamide 2 hydrochloride
|
T10994L
|
98%
|
|
Deltasonamide 2 hydrochloride is a competitive high-affinity PDEδ inhibitor with a Kd of approximately 385 pM.
|
TN4317 |
Isopedicin
|
4431-42-9
|
98%
|
|
Isopedicin has anti-inflammatory functions, it inhibits the O(2)(*)(-) production in human neutrophils by an elevation of cellular cAMP and activation of PKA thr...
|
T14962 |
CI-1044
|
197894-84-1
|
98%
|
|
CI-1044 is an inhibitor of PDE4 (IC50s: 0.29, 0.08, 0.56, 0.09 μM for PDE4A5, PDE4B2, PDE4C2 and PDE4D3).
|
TN4397 |
Kuraridine
|
34981-25-4
|
98%
|
|
Kuraridine is measured against cGMP PDE5 to identify potent cGMP specific phosphodiesterase type 5 inhibitory constituents.
|
T11483 |
GSK256066 Trifluoroacetate
|
1415560-64-3
|
98%
|
|
GSK 256066 Trifluoroacetate is a selective and high-affinity phosphodiesterase 4 (PDE) inhibitor (IC50: 3.2 pM for PDE4B). It can be used for the treatment of ch...
|
T11206 |
Ent-Tadalafil
|
629652-72-8
|
98%
|
|
ent-Tadalafil (ent-IC-351), compound (6S,12aS), is a inactive cis-enantiomer of compound (6R,12aS).
|
T16482 |
PF-05085727
|
1415637-72-7
|
98%
|
|
PF-05085727 inhibits PDE2A >4,000-fold selectivity over PDE1 and PDE3-11. PF-05085727 is an effective, selective and brain penetrant inhibitor of cGMP-dependent ...
|
T10418 |
Autotaxin modulator 1
|
1548743-69-6
|
98%
|
|
Autotaxin modulator 1 is a new modulator of Autotaxin.
|
TN4665 |
Norbraylin
|
60796-64-7
|
98%
|
|
Norbraylin is a natural product from Toddalia asiatica.
|