TN1525 |
Convallatoxin
|
508-75-8
|
98%
|
|
Convallatoxin is a natural product
|
T15567 |
Imiglitazar
|
250601-04-8
|
98%
|
|
Imiglitazar is a potent and dual human PPARα and PPARγ1 agonist (EC50: 67 and 31 nM).
|
TN2228 |
Soyasaponin Aa
|
117230-33-8
|
98%
|
|
Soyasaponin Aa and soyasaponin Ab dose-dependently markedly inhibit adipocyte differentiation and expression of various adipogenic marker genes, through the down...
|
T15336 |
Fonadelpar
|
515138-06-4
|
98%
|
|
Fonadelpar is an agonist of PPARδ. It also is used in the research of neuroparalytic keratopathy.
|
T15440 |
GSK376501A
|
1010412-80-2
|
98%
|
|
GSK376501A is a selective modulator of peroxisome proliferator-activated receptor gamma (PPARγ). It is used for the treatment of type 2 diabetes mellitus.
|
TN1681 |
Gentianine
|
439-89-4
|
98%
|
|
Gentianine has anti-diabetic, antipsychotic, anti-inflammatory, hypotensive, and diuretic actions, it could be developed as a safe antihypertensive drug.
|
TN3655 |
Cimiside E
|
154822-57-8
|
98%
|
|
Cimiside E has anti-inflammatory activity, it selectively inhibits TNF-α-induced expression of VCAM-1 at least by upregulation of PPAR-γ, and signals for ERK1/2,...
|
T15049 |
Daltroban
|
79094-20-5
|
98%
|
|
Daltroban is a specific thromboxane A2 (TXA2) receptor antagonist. Daltroban shows protective effect in reperfusion injury. Daltroban increase intracellular calc...
|
TN2641 |
15-Methoxypinusolidic acid
|
769928-72-5
|
98%
|
|
15-Methoxypinusolidic acid has anti-inflammatory effects, it inhibits LPS-induced iNOS expression and NO production, independent on MAPK and NF-kappaB. 15-Methox...
|
TN3219 |
7,8-Didehydrocimigenol
|
150972-72-8
|
98%
|
|
7,8-Didehydrocimigenol can be used for the treatment of cardiovascular disorders such as atherosclerosis. It upregulates PPAR-γ in EC inhibits NF-kB activity of ...
|
TN3989 |
Erycibelline
|
107633-95-4
|
98%
|
|
Erycibelline has antiobesity activity, it may be a useful therapeutic agent for body weight control by downregulating adipogenesis and lipogenesis.
|
T10327 |
Ankaflavin
|
50980-32-0
|
98%
|
|
Ankaflavin is isolated from Monascus-Fermented red rice and is a PPARγ agonist with anti-inflammatory activity. It shows the selective cytotoxic effect and induc...
|
TMA0127 |
Ficusin A
|
173429-83-9
|
98%
|
|
Ficusin has antioxidant, antilipidemic and antidiabetic effects, it can lower the levels of fasting blood glucose, plasma insulin, body weight gain in HFD-STZ in...
|
T16739 |
RG-12525
|
120128-20-3
|
98%
|
|
RG-12525 is a PPAR-gamma agonist (IC50: appr 60 nM) and a potent inhibitor of CYP3A4 (Ki: 0.5 µM). RG-12525 is a specific and competitive antagonist of the pepti...
|
TN5149 |
Tirotundin
|
56377-67-4
|
98%
|
|
Tirotundin is a PPARα/γ dual agonist, it exerts anti-diabetic effect through PPARγ pathway. It shows anti-inflammatory activity, it inhibits inhibit the activati...
|
T10506 |
PPAR agonist 1
|
539813-69-9
|
98%
|
|
PPAR agonist 1 is an agonist of PPAR α/γ, used for reducing blood glucose, lipid levels, reducing body weight, and lowering cholesterol.
|
TN1703 |
Glycyrin
|
66056-18-6
|
98%
|
|
Glycyrin, one of the main PPAR-gamma ligands of licorice, can significantly decrease the blood glucose levels of genetically diabetic KK-A(y) mice.
|
TN5091 |
Tagitinin A
|
59979-61-2
|
98%
|
|
Tagitinin A is a plant insecticidal compound, it has phytotoxic activity, it shows significant inhibition of wheat coleoptile growth, seed germination, and the g...
|
TN4094 |
Gallocatechin gallate
|
5127-64-0
|
98%
|
|
Gallocatechin gallate has strong antioxidative, and anti-obesity activities, it inhibits 3T3-L1 differentiation and lipopolysaccharide induced inflammation throu...
|
TWS0787 |
Oroxin A
|
31567-75-6
|
98%
|
|
Oroxin A is a partial PPARγ agonist that can activate PPARγ transcriptional activation in vitro and in vivo. Oroxin A also exhibited inhibitory activity against ...
|