T14500 |
BAY-1316957
|
1613264-40-6
|
98%
|
|
BAY-1316957 is a highly potent and selective EP4 receptor antagonist. With an IC50 of 15.3 nM. Good oral bioavailability[1].
|
TN4592 |
Murrangatin
|
37126-91-3
|
98%
|
|
Murrangatin may be a valuable anti-tumor-promoting agent, it can significantly inhibit Epstein-Barr virus early antigen (EBV-EA) activation, and preserve the hig...
|
T16011 |
Manumycin A
|
52665-74-4
|
98%
|
|
Manumycin A is an antibiotic. Manumycin A induces apoptosis and exerts antitumor activity. Manumycin A inhibits exosome biogenesis and secretion via targeted inh...
|
TN1171 |
6-Dehydrogingerdione
|
76060-35-0
|
98%
|
|
1-Dehydro-6-gingerdione is a 5-HT1A receptor partial agonist.
|
TN4420 |
Latifolin
|
10154-42-4
|
98%
|
|
Latifolin is a strong DPPH-scavenger, it attenuates inflammatory responses by inhibiting NF-κB activation via Nrf2-mediated heme oxygenase-1 expression. Latifol...
|
T4624 |
PGD2-IN-1
|
885066-67-1
|
98%
|
|
PGD2-IN-1 is an antagonist of DP extracted from patent WO 2006044732 A2, example 15 (d)
|
TN3582 |
Canniprene
|
70677-47-3
|
98%
|
|
Canniprene has anti-inflammatory activity, it can potently inhibit the production of inflammatory eicosanoids via the 5-lipoxygenase pathway (IC50=0.4uM) and als...
|
TN1485 |
Chicanine
|
78919-28-5
|
98%
|
|
Chicanine has anti-inflammatory activity in macrophages by down-regulating LPS-induced inflammatory cytokines in IκBα±/MAPK/ERK signaling pathways.
|
TN4675 |
Nortrachelogenin
|
34444-37-6
|
98%
|
|
Nortrachelogenin is a novel agent for prostate cancer therapy with ability to inhibit Akt membrane localization and activity as well as the activation of growth ...
|
TMA1570 |
Sappanone A
|
102067-84-5
|
98%
|
|
Sappanone A is the first homoisoflavanone to be discovered with melanogenesis inhibitory activity. It exerts its anti-inflammatory effect by modulating the Nrf2 ...
|
TN1009 |
Epimagnolin B
|
1134188-26-3
|
98%
|
|
Epimagnolin B has anti-inflammatory activity, it can inhibit the production of NO and PGE(2) and the expression of respective enzyme iNOS and COX-2 through the s...
|
TN5011 |
Shizukaol B
|
142279-40-1
|
98%
|
|
Shizukaol B exerts anti-inflammatory effects in LPS-activated microglia partly by modulating JNK-AP-1 signaling pathway; it also shows significant anti-neuroinfl...
|
TN1077 |
Taraxerol
|
127-22-0
|
98%
|
|
Taraxerol can be used as a lipid biomarker for mangrove input to the SE Atlantic.
|
TN2169 |
Saikogenin D
|
5573-16-0
|
98%
|
|
Saikogenin D possesses a dual effect: an inhibition of A23187-induced PGE2 production without a direct inhibition of cyclooxygenase activity; and an elevation of...
|
TN1622 |
Ermanin
|
20869-95-8
|
98%
|
|
Ermanin shows anti-inflammatory activity by suppressing the iNOS and COX-2 expression. Ermanin may have anti-HIV-1activity. Ermanin also has a high deterrent act...
|
TN4489 |
Manassantin A
|
88497-87-4
|
98%
|
|
Manassantin A is a high potent HIF-1 inhibitor, it protects the gastric mucosa from ethanol-induced acute gastric injury, and suggest that these protective effec...
|
TN4162 |
Goshonoside F5
|
90851-28-8
|
98%
|
|
Goshonoside F5 has anti-inflammatory activity, it significantly inhibits the pro-inflammatory response induced by LPS, both in vitro and in vivo.
|
T16988 |
Taprenepag isopropyl
|
1005549-94-9
|
98%
|
|
Taprenepag isopropyl is a highly selective agonist of the EP2 receptor.
|
T14146 |
AGN 210676
|
910562-15-1
|
98%
|
|
AGN 210676 is a selective agonist of prostaglandin EP2(EC50 : 5 nM).
|
T2573 |
Misoprostol
|
59122-46-2
|
98%
|
|
|