T5373 |
Acrizanib
|
LHA510 |
VEGFR
|
|
Acrizanib is a VEGFR-2 inhibitor, with an IC50 of 17.4 nM for BaF3-VEGFR-2. |
T21593 |
AAL-993
|
|
VEGFR
|
|
AAL-993 is a potent VEGFR inhibitor with IC50s of 130 nM, 23 nM and 18 nM for VEGFR1, VEGFR2 and VEGFR3, respectively. A... |
T60094 |
SU 4981
|
|
Tyrosine Kinases
,
VEGFR
|
|
SU 4981 is an inhibitor of VEGFR and a modulator of tyrosine kinase activity. |
T2496 |
(Z)-Semaxinib
|
SU5416 |
VEGFR
|
|
Semaxanib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor (IC50: 1.23 μM), 20-fold more selective for VEGF... |
T12145L |
N-Desethylsunitinib hydrochloride
|
|
VEGFR
,
PDGFR
,
c-Kit
|
|
N-Desethylsunitinib hydrochloride is a major and pharmacologically active metabolite of sunitinib, which is potent, ATP-... |
T9724 |
WAY-340935
|
|
Others
|
|
WAY-340935 has anti-inflammatory and analgesic activities. |
T9979 |
WAY-302159
|
|
VEGFR
|
|
WAY-302159 is a VEGFR2 inhibitor. |
T6996 |
SU 5402
|
SU5402 |
VEGFR
,
FGFR
,
PDGFR
|
|
SU5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, F... |
TQ0059 |
Ilorasertib
|
ABT-348 |
FLT
,
c-RET
,
VEGFR
,
Aurora Kinase
,
PDGFR
|
|
Ilorasertib (ABT-348) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora A/Aurora B/Aurora C (I... |
T0520 |
Lenvatinib
|
E7080 |
VEGFR
,
FGFR
,
c-RET
,
PDGFR
,
c-Kit
|
|
Lenvatinib is a Kinase Inhibitor. The mechanism of action of lenvatinib is as a Receptor Tyrosine Kinase Inhibitor. |
TQ0166 |
Tesevatinib
|
XL-647 , EXEL-7647 , KD-019 |
VEGFR
,
EGFR
,
FLT
,
Ephrin Receptor
|
|
Tesevatinib is an orally available, multi-target tyrosine kinase inhibitor (IC50s: 0.3, 16, 1.5, 8.7, and 1.4 nM for EGF... |
T4315 |
Ki20227
|
|
CSF-1R
,
VEGFR
,
c-Fms
,
c-Kit
,
PDGFR
|
|
Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM). It also has certain inhibitory against VEGFR... |
T5164 |
Cabozantinib hydrochloride
|
Cabozantinib hydrochloride (849217-68-1(free base)) , BMS-907351 , XL184 |
c-Met/HGFR
,
FLT
,
VEGFR
,
TAM Receptor
,
ROR
,
c-Kit
|
|
Cabozantinib (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: ... |
TWA2417 |
Sodium taurocholate
|
Taurocholate Sodium |
Others
|
|
Taurocholic acid is the main end product of cholesterol catabolism. During enterohepatic circulation, bile taurocholic a... |
T61561 |
VEGFR-2-IN-18
|
|
|
|
VEGFR-2-IN-18 (Compound 15d) is a potent VEGFR-2 inhibitor with an IC 50 of 60 nM. VEGFR-2-IN-18 induces cell apoptosis.... |
T61861 |
VEGFR-2-IN-20
|
|
|
|
VEGFR-2-IN-20 (Compound 7) is a potent inhibitor of VEGFR. VEGFR-2-IN-20 has the potential for the research of cancer di... |
T61631 |
VEGFR-2-IN-23
|
|
|
|
VEGFR-2-IN-23 (compound 11b) is a potent and selective VEGFR-2 inhibitor with an IC 50 value of 0.34 nM. VEGFR-2-IN-23 s... |
T61137 |
VEGFR-2-IN-19
|
|
|
|
VEGFR-2-IN-19 (Compound 15b) is a potent VEGFR2 inhibitor. VEGFR-2-IN-19 induces cell apoptosis and increases intracellu... |
T61542 |
VEGFR-2-IN-17
|
|
|
|
VEGFR-2-IN-17 (Compound 15a) is a potent VEGFR-2 inhibitor with an IC 50 of 67.25 nM. VEGFR-2-IN-17 shows antitumor acti... |
T61038 |
VEGFR-2-IN-10
|
|
|
|
VEGFR-2-IN-10 has enhanced antiangiogenic potency against VEGFR2 phosphorylation induced by VEGF with an IC50 value of 0... |