Search Result

Search Results for "vegfr"

Targets

Libraries

FDA-Approved Kinase Inhibitor Library Kinase Inhibitor Library

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Compounds

Cat No.	Product Name
T5373	Acrizanib	LHA510	VEGFR
	Acrizanib is a VEGFR-2 inhibitor, with an IC50 of 17.4 nM for BaF3-VEGFR-2.		VEGFR
T21593	AAL-993		VEGFR
	AAL-993 is a potent VEGFR inhibitor with IC50s of 130 nM, 23 nM and 18 nM for VEGFR1, VEGFR2 and VEGFR3, respectively. A...		VEGFR
T60094	SU 4981		Tyrosine Kinases , VEGFR
	SU 4981 is an inhibitor of VEGFR and a modulator of tyrosine kinase activity.		Tyrosine Kinases , VEGFR
T2496	(Z)-Semaxinib	SU5416	VEGFR
	Semaxanib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor (IC50: 1.23 μM), 20-fold more selective for VEGF...		VEGFR
T12145L	N-Desethylsunitinib hydrochloride		VEGFR , PDGFR , c-Kit
	N-Desethylsunitinib hydrochloride is a major and pharmacologically active metabolite of sunitinib, which is potent, ATP-...		VEGFR , PDGFR , c-Kit
T9724	WAY-340935		Others
	WAY-340935 has anti-inflammatory and analgesic activities.		Others
T9979	WAY-302159		VEGFR
	WAY-302159 is a VEGFR2 inhibitor.		VEGFR
T6996	SU 5402	SU5402	VEGFR , FGFR , PDGFR
	SU5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, F...		VEGFR , FGFR , PDGFR
TQ0059	Ilorasertib	ABT-348	FLT , c-RET , VEGFR , Aurora Kinase , PDGFR
	Ilorasertib (ABT-348) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora A/Aurora B/Aurora C (I...		FLT , c-RET , VEGFR , Aurora Kinase , PDGFR
T0520	Lenvatinib	E7080	VEGFR , FGFR , c-RET , PDGFR , c-Kit
	Lenvatinib is a Kinase Inhibitor. The mechanism of action of lenvatinib is as a Receptor Tyrosine Kinase Inhibitor.		VEGFR , FGFR , c-RET , PDGFR , c-Kit
TQ0166	Tesevatinib	XL-647 , EXEL-7647 , KD-019	VEGFR , EGFR , FLT , Ephrin Receptor
	Tesevatinib is an orally available, multi-target tyrosine kinase inhibitor (IC50s: 0.3, 16, 1.5, 8.7, and 1.4 nM for EGF...		VEGFR , EGFR , FLT , Ephrin Receptor
T4315	Ki20227		CSF-1R , VEGFR , c-Fms , c-Kit , PDGFR
	Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM). It also has certain inhibitory against VEGFR...		CSF-1R , VEGFR , c-Fms , c-Kit , PDGFR
T5164	Cabozantinib hydrochloride	Cabozantinib hydrochloride (849217-68-1(free base)) , BMS-907351 , XL184	c-Met/HGFR , FLT , VEGFR , TAM Receptor , ROR , c-Kit
	Cabozantinib (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: ...		c-Met/HGFR , FLT , VEGFR , TAM Receptor , ROR , c-Kit
TWA2417	Sodium taurocholate	Taurocholate Sodium	Others
	Taurocholic acid is the main end product of cholesterol catabolism. During enterohepatic circulation, bile taurocholic a...		Others
T61561	VEGFR-2-IN-18
	VEGFR-2-IN-18 (Compound 15d) is a potent VEGFR-2 inhibitor with an IC 50 of 60 nM. VEGFR-2-IN-18 induces cell apoptosis....
T61861	VEGFR-2-IN-20
	VEGFR-2-IN-20 (Compound 7) is a potent inhibitor of VEGFR. VEGFR-2-IN-20 has the potential for the research of cancer di...
T61631	VEGFR-2-IN-23
	VEGFR-2-IN-23 (compound 11b) is a potent and selective VEGFR-2 inhibitor with an IC 50 value of 0.34 nM. VEGFR-2-IN-23 s...
T61137	VEGFR-2-IN-19
	VEGFR-2-IN-19 (Compound 15b) is a potent VEGFR2 inhibitor. VEGFR-2-IN-19 induces cell apoptosis and increases intracellu...
T61542	VEGFR-2-IN-17
	VEGFR-2-IN-17 (Compound 15a) is a potent VEGFR-2 inhibitor with an IC 50 of 67.25 nM. VEGFR-2-IN-17 shows antitumor acti...
T61038	VEGFR-2-IN-10
	VEGFR-2-IN-10 has enhanced antiangiogenic potency against VEGFR2 phosphorylation induced by VEGF with an IC50 value of 0...