GABA Receptor

The GABA receptors are a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid (GABA), the chief inhibitory compound in the mature vertebrate central nervous system. There are two classes of GABA receptors: GABAA and GABAB. GABAA receptors are ligand-gated ion channels (also known as ionotropic receptors); whereas GABAB receptors are G protein-coupled receptors, also called metabotropic receptors.

Cat. No.	Product name	CAS No.	Purity
T10456	Bamaluzole	87034-87-5	98%
T10456	Bamaluzole is an agonist of GABA receptor extracted from patent WO 2012064642 A1.
T4S1616	Sanggenon D	81422-93-7	98%
T4S1616	Sanggenone D represents a new scaffold of positive GABAA receptor modulators, it also inhibits COX-2 activity (IC 50 = 73-100 μM). Sanggenone D has anti-inflamma...
T0128L	Vigabatrin Hydrochloride	1391054-02-6	98%
T0128L	Vigabatrin HCl is a structural analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA), which irreversibly inhibits the catabolism of GABA by GABA t...
TN1591	DL-Menthol	15356-70-4	98%
TN1591	DL-Menthol has short term toxicity in rats, it plays a role in the induction of surgical anesthesia in fishes, related at least in part to the activation of GABA...
TN4440	Limonexic acid	99026-99-0	98%
TN4440	Limonexic acid shows antinociceptive actions , it produces dose-related inhibition of glutamate- and capsaicin-induced pain. Limonexic acid can effectively prote...
T12044	(-)-Bicuculline methochloride	53552-05-9	98%
T12044	(-)-Bicuculline methochloride is a potent antagonist of GABAA receptor.
T15737	Lesogaberan	344413-67-8	98%
T15737	Lesogaberan is an effective and selective GABAB receptor agonist (EC50: 8.6 nM for human recombinant GABAB receptors). For rat brain GABAB and GABAA receptors, t...
TN1202	(-)-α-Pinene	7785-26-4	98%
TN1202	(1S)-(-)-Alpha-Pinene is a natural product
T40659L	γ-Acetylenic GABA hydrochloride	103451-26-9	98%
T40659L	γ-Acetylenic GABA hydrochloride is a GABA transaminase inhibitor.
T12867L	SCH 50911	733717-87-8	98%
T12867L	SCH 50911 is (+)-(S)-5,5-dimethylmorpholinyl-2-acetic acid and is a selective, orally-active and competitive γ-Aminobutyric acid B GABA(B) receptor antagonist, b...
T15380	Gidazepam	129186-29-4	98%
T15380	Gidazepam is an GABA receptor channels agonist.
T11686	Isotanshinone I	20958-17-2	98%
T11686	Isotanshinone I with IC50s of 1.13 μM and 0.432 μM for α-glucosidase and AGE, respectively. Isotanshinone I has inhibitory activity against α-glucosidase and for...
T3173	DAA-1106	220551-92-8	98%
T3173	DAA1106 is a potent and selective ligand for peripheral benzodiazepine receptor (PBR), acting as a potent and selective agonist at the peripheral benzodiazepine ...
T12867	SCH 50911 hydrochloride	160415-07-6	98%
T12867	SCH 50911 hydrochloride is a selective, orally-active and competitive antagonist of γ-Aminobutyric acid B GABA(B) receptor(IC50 : 1.1 μM).
T9424	Temgicoluril	10095-06-4	98%
T9424	Temgicoluril acts on GABA Receptor.
T12043	(-)-Bicuculline methobromide	73604-30-5	98%
T12043	(-)-Bicuculline methobromide is a potent antagonist of GABAA receptor .
T13150	THIP	64603-91-4	98%
T13150	THIP is a selective agonist of δ-aminobutyric acid type A receptor (δ-GABAAR),and exhibits agonism at α4β1δ, α4β3δ and weak antagonism at αβγ and α4β2δ GABAARs.
TN4322	Isopulegol	7786-67-6	98%
TN4322	Isopulegol presents depressant- and anxiolytic-like effects, it also has anticonvulsant and bioprotective effects against PTZ-induced convulsions are possibly re...
T11061	DMCM hydrochloride	1215833-62-7	98%
T11061	DMCM hydrochloride is a non-selective fully inverse agonist of benzodiazepine. DMCM showed significant differences in human recombinant GABAA zaerxep3 receptor s...
T17306	(R)-Baclofen hydrochloride	63701-55-3	98%
T17306	Arbaclofen hydrochloride, a Gamma-Aminobutyric Acid derivative, is a specific agonist of GABA-B receptors, it is used to treat spasticity, especially that due to...