2,4,5,6-tetraaminopyrimidine

2,4,5,6-Tetraaminopyrimidine is a coloring agent.

2-(4-Hydroxyphenylazo)benzoicacid is a spectrophotometric probe that shows changes in absorption spectra upon binding to proteins and binds to bovine serum proteins.

5-Bromo-4-chloro-3-indoxyl-beta-D-cellobioside is a chromogenic compound used to detect cellobiohydrolases.

6-Ethyl-7-hydroxy-4-methylchromen-2-one is a fluorescent dye.

Pyridine-2-carboxaldehyde 4-nitrophenylhydrazone (PCNPH) acts as a chromogenic substrate for peroxidase enzymes, producing a purple indamine dye when reacting with peroxidases and peroxides [1].

4-(2-Aminoethylamino)-7-(N,N-dimethylsulfamoyl)benzofurazan functions as a precolumn fluorescence derivatization reagent.

5(6)-Carboxy-2',7'-dichlorofluorescein serves as an excellent substrate for the MRP2 vesicular transport assay, offering superior detection and transport characteristics [1].

N-[5-2-[Azo]phenyl]acetamide serves as a multifunctional dye used extensively across various fields. In the realm of biological experiments, this dye is instrumental for observing and analyzing cell structures, tracking biomolecules, evaluating cell functions, distinguishing cell types, detecting biomolecules, studying tissue pathology, and monitoring microorganisms. Its usage spans from fundamental scientific research to a broad spectrum of clinical diagnostics. Additionally, this compound finds applications in traditional industries like textile dyeing and emerging areas including functional textile processing, food pigments, and dye-sensitized solar cells.

4',5'-Dibromofluorescein (Eosinic acid) is a fluorescent dye utilized as a ligand in protein characterization through spectroscopic analysis.

10-(4-(Bis(2-acetoxyethyl)amino)phenyl)-BODIPY 505 515 serves as a fluorescent dye specifically for Cu 2+ ions [1].

C.I. Food Blue 5:2, a multifunctional dye, serves various roles in both scientific and traditional industries. In research and clinical diagnostics, it facilitates the observation and analysis of cell structures, tracking of biomolecules, evaluation of cell functions, differentiation of cell types, detection of biomolecules, tissue pathology studies, and monitoring of microorganisms. Additionally, its uses extend to traditional textile dyeing and emerging applications in functional textile processing, food pigments, and dye-sensitized solar cells.

2'(3')-O-Anthraniloyladenosine-5'-O-triphosphate (2'-ANT-ATP) and its isomer 3'-ANT-ATP are fluorescent derivatives of ATP that spontaneously isomerize. Emitting a maximum light of 428 nm when excited at 330 nm in water, 2'(3')-ANT-ATP specifically inhibits several types of adenylyl cyclase (AC) including mammalian AC1, AC2, and AC5 with inhibition constants (Kis) of 130, 640, and 120 nM, respectively. It also inhibits Bordetella pertussis AC toxin CyaA with Kis of 1.3 µM (in the presence of manganese) and 20 µM (in the presence of magnesium), Bacillus anthracis AC toxin edema factor with Kis of 0.44 µM (with manganese) and 5.15 µM (with magnesium), and Escherichia coli recombinase A (RecA) with a Ki of 6.3 µM.

Sodium 2,2',2'',2'''-((((1,1-dioxido-3H-benzo[c][1,2]oxathiole-3,3-diyl)bis(6-hydroxy-5-isopropyl-2-methyl-3,1-phenylene))bis(methylene))bis(azanetriyl))tetraacetate is a useful organic compound for research related to life sciences. The catalog number is T65315 and the CAS number is 1945-77-3.

7-(Diethylamino)-4-methyl-2H-chromen-2-one is a useful organic compound for research related to life sciences. The catalog number is T66262 and the CAS number is 91-44-1.

4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoyl chloride (DIB-Cl) serves as a fluorescent labeling reagent. It is utilized for labeling amines and has been successfully applied in the determination of activator amines using HPLC [1].

AMCA-X, N-succinimidyl ester is an amine-reactive, UV-excitable, blue fluroscent dye.

2-(Naphthalen-1-yl)-5-phenyloxazole (α-NPO) is an organic fluorescent dye featuring a nitrogen atom, potentially interacting with nitrogen introduced during the amination step [1].

5-Bromo-4-chloro-3-indolyl-b-D-glucuronide sodium salt is a useful organic compound for research related to life sciences. The catalog number is T64896 and the CAS number is 129541-41-9.

5-Bromo-4-chloro-3-indolyl β-D-glucopyranoside, a chromogenic substrate, is widely utilized in molecular biology for β-galactosidase activity detection, especially in gene expression and reporter gene analysis. When cleaved by β-galactosidase, it yields a blue precipitate visible through microscopy or alternative detection techniques. Known for its high sensitivity and specificity, it remains a valuable asset in molecular biology research.

2-(7-Hydroxy-2-oxo-2H-chromen-4-yl)acetic acid is a useful organic compound for research related to life sciences. The catalog number is T65277 and the CAS number is 6950-82-9.

2-(7-Methoxy-2-oxo-2H-chromen-4-yl)acetic acid is a useful organic compound for research related to life sciences. The catalog number is T64951 and the CAS number is 62935-72-2.

5(6)-Carboxy-2’,7’-dichlorofluorescein diacetate is an oxidant-sensitive and cell-permeable fluorescent probe.1Base hydrolysis of the ester bonds by intracellular esterases releases the acetate groups and the resulting compound, 5(6)-carboxy-2’,7’,-dichlorofluorescein, is oxidized by reactive oxygen species (ROS) and nitric oxide (NO) and displays excitation/emission maxima of 504 and 530 nm, respectively, which can be quantified as a measure of oxidant production. 1.Hempel, S.L., Buettner, G.R., O’Malley, Y.Q., et al.Dihydrofluorescein diacetate is superior for detecting intracellular oxidants: Comparison with 2’,7’-dichlorodihydrofluorescein diacetate, 5(and 6)-carboxy-2’,7’-dichlorodihydrofluorescein diacetate, and dihydrorhodamine 123Free Radic. Biol. Med.27(1-2)146-159(1999)

DMTr-4'-F-5-Me-U-CED phosphoramidite (DMTr-4'-F-5-Methyluridine-CED phosphoramidite) serves as a dye reagent for oligonucleotide labeling, offering effectiveness comparable to native deoxyribonucleoside phosphoramidites. This compound functions as a critical building block [1].

N-[4-(2-Benzimidazolyl)phenyl]maleimide is a potent fluorescent probe with an excitation maximum at 315 nm and an emission maximum at 360 nm, suitable for the fluorometry of thiol compounds [1].

4-(Benzyloxy)-2-nitrophenol serves as a synthetic precursor for constructing fluorescent ion indicators [1].

4-Methylumbelliferyl 2-sulfamino-2-deoxy-α-D-Glucopyranoside (4-MU-α-GlcNS) is a fluorogenic substrate of heparin sulphamidase. Heparin sulphamidase cleaves 4-MU-α-GlcNS to yield 4-MU-α-GlcNH2, which is then cleaved by α-glucosaminidase to release the fluorescent product 4-MU, which displays an emission maxima of 445-454 nm. The excitation maxima for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively. 4-MU-α-GlcNS has been used to quantify heparin sulphamidase deficiencies associated with Mucopolisaccaridosis IIIA and other lysosomal disorders.

Sodium 2,6-dibromo-4-(3-(3,5-dibromo-4-hydroxy-2-methylphenyl)-2,2-dioxido-3H-benzo[d][1,2]oxathiol-3-yl)-3-methylphenolate is a useful organic compound for research related to life sciences. The catalog number is T64788 and the CAS number is 62625-32-5.

4-Methyl-2-phenylchromenylium tetrafluoroborate serves as a fluorescent dye [1].

4-Di-2-ASP, a styryl pyridinium fluorescent dye, serves as an essential mitochondrial marker. It effectively and specifically labels pulmonary NEBs (neuroepithelial bodies) [1].

Flutax-2 (5/6-mixture), an active fluorescent derivative of paclitaxel, binds to polymerized α,β tubulin dimers, with an excitation/emission wavelength of 496/524 nm. Derived from paclitaxel, a diterpenoid secondary metabolite from Taxus species utilized in various cancer research [1], it requires storage protection from light.

Sodium 4-(3-(4-hydroxy-5-isopropyl-2-methylphenyl)-1,1-dioxido-3H-benzo[c][1,2]oxathiol-3-yl)-2-isopropyl-5-methylphenolate is a useful organic compound for research related to life sciences. The catalog number is T66669 and the CAS number is 62625-21-2.

2-([1,1-Biphenyl]-4-yl)-5-phenyl-1,3,4-oxadiazole is a useful organic compound for research related to life sciences. The catalog number is T66233 and the CAS number is 852-38-0.

2'-Deoxy-1,N6-ethenoadenosine-5'-O-triphosphate (ε-dATP), a fluorescent derivative of 2’-deoxyadenosine-5’-O-triphosphate (dATP), promotes sister chromatid exchange in stimulated primary mouse spleen T- and B lymphocytes with LPS or concanavalin A at concentrations of 50 to 150 µM. Utilized in ambiguous base pairing investigations within vinyl chloride-induced mutagenesis research, ε-dATP, along with its related compound ε-ATP—which exhibits an emission peak at 415 nm after being excited at 300 nm—contributes to understanding genetic alterations mechanisms.

7-Hydroxy-4-methyl-2(1H)-quinolone (compound 2b), a fluorescent hydroxylated derivative, serves as a probe for detecting hydroxyl radicals associated with DNA damage [1]. It should be protected from light for preservation.