T9618 |
HeE1-2Tyr
|
|
SARS-CoV
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|
HeE1-2Tyr, a pyridobenzothiazole compound, is a flavivirus RNA dependent RNA polymerases (RdRp) inhibitor. It significan... |
T40276 |
GS-621763
|
|
SARS-CoV
|
|
GS-621763, a prodrug of GS-441524, exhibits antiviral activity against SARS-CoV-2 pathogenesis. |
T9617 |
RdRP-IN-2
|
|
SARS-CoV
|
|
RdRP-IN-2 is a RNA dependent RNA polymerase (RdRp) inhibitor. It significantly inhibits SARS-CoV-2 RdRp with an IC50 of ... |
T9614 |
MERS-CoV-IN-1
|
|
SARS-CoV
|
|
MERS-CoV-IN-1 exhibits excellent inhibitory activity against coronavirus.It is useful as a pharmaceutical composition fo... |
T60045 |
NK01-63
|
NK01 63 |
SARS-CoV
|
|
Coronastat is a potent inhibitor of the SARS-CoV-2 3CL protease. |
T9876 |
Piperazine, 1-(4-fluorophenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]-
|
|
Others
|
|
Piperazine,1-(4-fluorophenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]- is a piperazine derivative with anti-SARS-CoV-2 activi... |
T60016 |
VV116
|
GS-621763-d1 hydrobromide , JT001 |
SARS-CoV
,
RSV
|
|
VV116 is a selective and orally active nucleoside antiviral agent against respiratory syncytial virus (RSV) and SARS-CoV... |
T0860L |
Mefloquine
|
Ro215998 , Ro-215998 , Ro 215998 , WR 142490 , Lariam |
Others
|
|
Mefloquine is a phospholipid-interacting antimalarial drug effective against Plasmodium Falciparium with very few side e... |
T9293 |
SSAA09E3
|
|
SARS-CoV
|
|
SSAA09E3 is a novel inhibitor of SARS-CoV replication, acting by preventing fusion of the viral membrane with the host c... |
T60085 |
MM3122
|
MM-3122 , GTPL11533 , Ac-GQFR-kbt |
SARS-CoV
|
|
MM3122 is a selective type II transmembrane serine protease (TMPRSS2) inhibitor, IC50 = 0.34 nM. MM3122 effectively bloc... |
T21727 |
Ivermectin B1a
|
|
SARS-CoV
,
Parasite
|
|
Ivermectin B1a is the major (80%) component of commercially available ivermectin and a derivative of Avermectin B1a. |
T22394 |
Paritaprevir
|
ABT-450 , ABT450 , Veruprevir |
HCV Protease
|
|
ABT-450 is a inhibitor of nonstructural (NS) protein 3/4A protease. |
T3089 |
6-Thioguanine
|
2-Amino-6-mercaptopurine , Thioguanine , 6-TG , 2-Amino-6-purinethiol |
DNA Methyltransferase
,
Apoptosis
,
SARS-CoV
,
Endogenous Metabolite
,
DUB
,
Autophagy
|
|
Thioguanine is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute... |
T4557 |
Amylmetacresol
|
5-Methyl-2-Pentylphenol |
Others
,
HIV Protease
|
|
Amylmetacresol is used in the treatment of sore throat or 'acute sore throat', pharyngitis, tonsillitis and laryngitis. ... |
T4686 |
Simeprevir
|
TMC-435350 , TMC435 |
SARS-CoV
,
HCV Protease
|
|
Simeprevir is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM. |
T40660 |
Kansuinine B
|
|
IL Receptor
,
SARS-CoV
|
|
Kansuinine B inhibits Stat3 activation induced by IL-6. Kansuinine B exhibits anti-viral activity and could be used in C... |
T1131 |
Ivermectin
|
MK-933 |
GluCls
,
P2X Receptor
,
Mitophagy
,
SARS-CoV
,
HIV Protease
,
Antibiotic
,
Parasite
,
Autophagy
,
HSV
|
|
Ivermectin is a glutamate-gated chloride channel (GluCls) activator, with antiparasitic activity. |
T1076 |
Dexamethasone
|
MK 125 , Hexadecadrol , Prednisolone F , NSC 34521 |
Mitophagy
,
Glucocorticoid Receptor
,
IL Receptor
,
SARS-CoV
,
Autophagy
,
Complement System
,
Antibacterial
,
Antibiotic
|
|
Dexamethasone is a glucocorticoid receptor agonist and an IL receptor modulator.Dexamethasone inhibits production of exo... |
T36653 |
Anti-SARS-80R mAb
|
|
|
|
Anti-SARS-80R mAb (SARS-80R) is a human monoclonal IgG1 antibody produced in CHO cells. Anti-SARS-80R mAb can specifical... |
T40207 |
SARS-CoV-2-IN-7
|
|
|
|
SARS-CoV-2-IN-7 inhibits viral replication with a nanomolar IC 50 value (844 nM) in SARS-CoV-2-infected Vero E6 cells. |