GluR

Glutamate receptors are synaptic and non synaptic receptors located primarily on the membranes of neuronal and glial cells.Glutamate receptors are responsible for the glutamate-mediated postsynaptic excitation of neural cells, and are important for neural communication, memory formation, learning, and regulation.

Cat No.	product name
T29126	VU0360172	VU0360172 是 mGlu5 受体的正变构调节剂（EC50 = 16 nM；Ki = 195 nM）。
T23008L	MMPIP hydrochloride	MMPIP hydrochloride 是变构 mGluR7 的选择性拮抗剂。 MMPIP hydrochloride 可用于研究 mGluR7 对中枢神经系统功能的作用。
T9133	Caroverine hydrochloride	Caroverine HCL is a potent, competitive and reversible antagonist of NMDA and AMPA glutamate receptor. It is also an antioxidant and calcium-blocking agent that ...
T5083	L-Cysteic acid monohydrate	L-Cysteic acid is an oxidation product of L-cysteine that may be used as a competitive inhibitor of the bacterial aspartate: alanine antiporter (AspT) exchange o...
T7178	CNQX	CNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively)
T3379	Decanoic Acid	Decanoic Acid acts as a non-competitive AMPA receptor antagonist.
T4009	NS 1209	NS1209 is a AMPA receptor antagonist.
T1443	Memantine hydrochloride	Memantine hydrochloride is an AMANTADINE derivative that has some dopaminergic effects. Memantine hydrochloride has been proposed as an antiparkinson agent.
T0426	Piracetam	Piracetam, a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), is used in therapy of the extensive cognitive disorders.
T16402	Org-26576	Org-26576 is a positive allosteric modulator of the AMPA receptor.
T23259	(RS)-3-Hydroxyphenylglycine	PI-linked metabotropic glutamate receptors agonist
T3957	Farampator	Farampator (CX-691;Org24448) is an AMPA receptor positive modulator.
T1884	CX516	Ampalex (Ampakine CX516; CX516; BDP 12), an ampakine and nootropic, acts as an AMPA receptor positive allosteric modulator as a therapy for Alzheimer's disease, ...
T6871	L-Glutamic acid monosodium salt	L-Glutamic acid monosodium salt (Monosodium glutamate) is an activator of mGlu1 receptor.
T16977	Talampanel	Talampanel is an orally and selective α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor antagonist with anti-seizure activity. Talampanel attenuates casp...
T1324	O-Phospho-L-serine	Phosphoserine is the phosphoric acid ester of serine.
T7579	1-BCP	1-BCP is a centrally active drug that modulates AMPA receptor gated currents.
T0256	Citric acid trilithium salt tetrahydrate	Lithium Citrate, the active component of Lithium, is a medicine used in the therapy of psychiatric disease. It has shown the effects of signaling pathways and me...
T0051	Urethane	Urethane was an antineoplastic agent .Now is used for other medicinal purposes.
T6562	Latrepirdine dihydrochloride	Latrepirdine is an orally active, and neuroactive antagonist of multiple drug targets, including histamine receptors, GluR, and 5-HT receptors, used as an antihi...
T3010	Xanthurenic Acid	Xanthurenic acid, a molecule arising from tryptophan metabolism by transamination of 3-hydroxykynurenine, activates mGlu2/3 Metabotropic glutamate receptors (mGl...
T6468	D-glutamine	D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.
T19698	CX614	CX614 is a positive allosteric modulator of the AMPA receptor with respect to AMPA.
T2811	Harmine hydrochloride	Harmine hydrochloride is extracted from Peganum Harmala Genus.
T20571	Cis-PDA	cis-PDA, a general ionotropic receptor antagonist, acts by blocking NMDA, AMPA, and kainate mediated responses. It also acts as a partial NMDA receptor agonist.
T0333	Aniracetam	Aniracetam(Ro 13-5057), a nootropic and neuroprotective drug, selectively modulates the AMPA receptor and nAChR.
TN7044	S-(4-Hydroxybenzyl)glutathione	L-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain gluta...
T0675	Topiramate	Topiramate is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associated with hepat...
T37734	AMPA receptor modulator-2	AMPA receptor modulator-2 (Example 134) is a AMPA receptor modulator, with a pIC50 of 10.1 for TARPγ2 dependent AMPA receptor[1]. pIC50 = -lgIC50. [1]. BERRY CYN...
T7304	DNQX	DNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively)
T23291	(S)-3-Hydroxyphenylglycine	group I metabotropic glutamate receptors agonist
T4113	NBQX	Potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo.
T7706	LY-404187	LY404187 is a positive allosteric modulator of AMPA receptors
T8435	YM90K	YM90K hydrochloride is an antagonist of AMPA receptor.
T23514	VU-1545	VU 1545 is mGlu5 positive allosteric modulator.
T0326L	L-Glutamine	L-glutamine, a non-essential amino acid, is synthesized from glutamic acid and ammonia.
T21995	XAP044	XAP044 is a mGlu7-selective antagonist which inhibits lateral amygdala long term potentiation (LTP) in brain slices from wild type mice with a half-maximal block...
T2053	ADX-47273	ADX-47273 is a positive and selective allosteric modulator for the metabotropic glutamate receptor subtype mGluR5(EC50=170 nM).
T23515	VU-29	VU-29 is a positive allosteric mGlu5 receptor modulator with EC50=9 nM and Ki=244 nM for rmGluR5. It is selective for mGluR5 relative to other mGluR subtypes (EC...
T2497	MPEP hydrochloride	MPEP hydrochloride is an effective and highly specific non-competitive antagonist at the mGlu5 receptor subtype (IC50: 36 nM).
T22730	DL-AP3	DL-AP3 is a competitive group I metabotropic glutamate receptor antagonist and inhibitor of phosphoserine phosphatase.
T22641	CDPPB	CDPPB is a modulator of mGluR5 positive allosteric(with an EC50 of 27 nM in Chinese hamster ovary cells expressing human mGluR5).
T2194	Direct Blue 1	Chicago sky blue 6B, a vesicular glutamate transporters inhibitor, attenuates methamphetamine-induced hyperactivity and behavioral sensitization in mice.
T21935L	AMN082 free base	AMN082 is a metabotropic glutamate receptor 7 allosteric agonist.
T21935	AMN082	AMN 082 dihydrochloride is a selective metabotropic glutamate mGlu7 receptor agonist reported to exhibit antidepressant activity.
T9021	Ro0711401	Ro0711401 is an agonist of mGlu1 receptor.
T8862	ML 254	ML254 competitively interacts with the MPEP allosteric binding site. ML254 is highly selective for mGlu5 versus other mGlu receptors, has a clean ancillary Ricer...
T8626	4-oxo-1,4-dihydroquinoline-2-carboxylic acid	4-oxo-1,4-dihydroquinoline-2-carboxylic acid is a GluR and NMDA inhibitor.
T8779	HBT1	HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neurons....
T8434	SIB-1757	SIB-1757 is a selective antagonist of mGlu5 metabotropic glutamate receptor subtype (hmGlu5, IC50 : 0.4 μM)