GluR

Glutamate receptors are synaptic and non synaptic receptors located primarily on the membranes of neuronal and glial cells.Glutamate receptors are responsible for the glutamate-mediated postsynaptic excitation of neural cells, and are important for neural communication, memory formation, learning, and regulation.

Cat. No.	Product name	CAS No.	Purity
T23288L	(S)-3,4-DCPG HCl	T23288L	98%
T23288L	(S)-3,4-DCPG HCl is a selective metabotropic glutamate receptor 8a (mGluR8a) agonist that has an effect on human mGluR8-expressing AV12-664 cells with an EC50 of...
T23215L	(R)-3,4-DCPG HCl	T23215L	98%
T23215L	(R)-3,4-DCPG HCl is a potent and selective mGlu8a receptor agonist that activates metabotropic glutamate receptors on primary afferent terminals in the neonatal ...
T10881	CPPHA	693288-97-0	98%
T10881	CPPHA, a positive allosteric modulator of glutamate receptors mGluR5 and mGluR1, is commonly used in development for central nervous system diseases.
T10809L	CHPG hydrochloride	T10809L	98%
T10809L	CHPG hydrochloride is a selective agonist of mGluR5.
T14389	AZD 9272	327056-26-8	98%
T14389	AZD 9272 is a brain-permeable mGluR5 antagonist for the study of gastroesophageal reflux.
T10808	CHPG sodium salt	1303993-73-8	98%
T10808	CHPG sodium salt is a selective agonist of mGluR5 and activates the ERK and Akt signaling pathways. CHPG sodium salt can be used in studies about traumatic brain...
T27932	LY-2300559	889115-58-6	98%
T27932	LY-2300559 is an agonist of metabotropic glutamate receptor 2 (mGluR2) and can be used in studies about the treatment of migraine.
T4009	NS 1209	205645-02-9	98%
T4009	NS1209 is a AMPA receptor antagonist.
T15369	Gamma-DGG	6729-55-1	98%
T15369	gamma-DGG is a competitive blocker of AMPA receptor.
T11906	LY 541850	852679-76-6	98%
T11906	LY541850 is a selective orthosteric mGlu2 agonist and mGlu3 antagonist with IC50 values of 0.161 μM and 0.038 μM, respectively.LY 541850 is claimed from human io...
T15692	L-AP4	23052-81-5	98%
T15692	L-APB is an effective and specific agonist for the group III mGluRs (EC50s: 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6, and mGlu7 receptors, respectively).
T11907	Pomaglumetad methionil anhydrous	635318-55-7	98%
T11907	LY2140023 has the potential for schizophrenia.LY2140023 is an orally active prodrug of LY404039. LY404039 is a selective metabotropic glutamate 2/3 receptor agon...
T12520	Pomaglumetad methionil	956385-05-0	98%
T12520	Pomaglumetad methionil is an oral methionine prodrug of the potent specific agonist of mGlu2/3 receptor LY404039.
T12025	MFZ 10-7 hydrochloride	1779796-36-9	98%
T12025	MFZ 10-7 hydrochloride is a highly potent and selective negative allosteric modulator of mGluR5 NAM
T11911	LY3020371 hydrochloride	1377615-44-5	98%
T11911	LY3020371 hydrochloride exerts an antidepressant-like signature in vivo. LY3020371 hydrochloride is a potent, selective metabotropic glutamate 2/3 receptor (mGlu...
T15456	GYKI 53655 hydrochloride	143692-48-2	98%
T15456	GYKI53655 hydrochloride is an antagonist of α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA).
T21935	AMN082	97075-46-2	98%
T21935	AMN 082 dihydrochloride is a selective metabotropic glutamate mGlu7 receptor agonist reported to exhibit antidepressant activity.
T13319	VU0652835	1848252-81-2	98%
T13319	VU0652835 is a negative allosteric modulator of metabotropic glutamate receptor subtype 5 (mGlu5) (IC50: 81 nM).
T15618	JNJ-46281222	1254980-38-5	98%
T15618	JNJ-46281222 is an metabotropic glutamate (mGlu) 2-selective, highly potent PAM (positive allosteric modulator). It has nanomolar affinity (Kd = 1.7 nM) and a hi...
T11311L	Foliglurax	1883329-51-8	98%
T11311L	Foliglurax is a highly selective brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) (EC50: 79 nM).