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GluR

Glutamate receptors are synaptic and non synaptic receptors located primarily on the membranes of neuronal and glial cells.Glutamate receptors are responsible for the glutamate-mediated postsynaptic excitation of neural cells, and are important for neural communication, memory formation, learning, and regulation.
Cat No. product name
T29126 VU0360172 VU0360172 是 mGlu5 受体的正变构调节剂(EC50 = 16 nM;Ki = 195 nM)。
T23008L MMPIP hydrochloride MMPIP hydrochloride 是变构 mGluR7 的选择性拮抗剂。 MMPIP hydrochloride 可用于研究 mGluR7 对中枢神经系统功能的作用。
T9133 Caroverine hydrochloride Caroverine HCL is a potent, competitive and reversible antagonist of NMDA and AMPA glutamate receptor. It is also an antioxidant and calcium-blocking agent that ...
T5083 L-Cysteic acid monohydrate L-Cysteic acid is an oxidation product of L-cysteine that may be used as a competitive inhibitor of the bacterial aspartate: alanine antiporter (AspT) exchange o...
T7178 CNQX CNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively)
T3379 Decanoic Acid Decanoic Acid acts as a non-competitive AMPA receptor antagonist.
T4009 NS 1209 NS1209 is a AMPA receptor antagonist.
T1443 Memantine hydrochloride Memantine hydrochloride is an AMANTADINE derivative that has some dopaminergic effects. Memantine hydrochloride has been proposed as an antiparkinson agent.
T0426 Piracetam Piracetam, a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), is used in therapy of the extensive cognitive disorders.
T16402 Org-26576 Org-26576 is a positive allosteric modulator of the AMPA receptor.
T23259 (RS)-3-Hydroxyphenylglycine PI-linked metabotropic glutamate receptors agonist
T3957 Farampator Farampator (CX-691;Org24448) is an AMPA receptor positive modulator.
T1884 CX516 Ampalex (Ampakine CX516; CX516; BDP 12), an ampakine and nootropic, acts as an AMPA receptor positive allosteric modulator as a therapy for Alzheimer's disease, ...
T6871 L-Glutamic acid monosodium salt L-Glutamic acid monosodium salt (Monosodium glutamate) is an activator of mGlu1 receptor.
T16977 Talampanel Talampanel is an orally and selective α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor antagonist with anti-seizure activity. Talampanel attenuates casp...
T1324 O-Phospho-L-serine Phosphoserine is the phosphoric acid ester of serine.
T7579 1-BCP 1-BCP is a centrally active drug that modulates AMPA receptor gated currents.
T0256 Citric acid trilithium salt tetrahydrate Lithium Citrate, the active component of Lithium, is a medicine used in the therapy of psychiatric disease. It has shown the effects of signaling pathways and me...
T0051 Urethane Urethane was an antineoplastic agent .Now is used for other medicinal purposes.
T6562 Latrepirdine dihydrochloride Latrepirdine is an orally active, and neuroactive antagonist of multiple drug targets, including histamine receptors, GluR, and 5-HT receptors, used as an antihi...
T3010 Xanthurenic Acid Xanthurenic acid, a molecule arising from tryptophan metabolism by transamination of 3-hydroxykynurenine, activates mGlu2/3 Metabotropic glutamate receptors (mGl...
T6468 D-glutamine D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.
T19698 CX614 CX614 is a positive allosteric modulator of the AMPA receptor with respect to AMPA.
T2811 Harmine hydrochloride Harmine hydrochloride is extracted from Peganum Harmala Genus.
T20571 Cis-PDA cis-PDA, a general ionotropic receptor antagonist, acts by blocking NMDA, AMPA, and kainate mediated responses. It also acts as a partial NMDA receptor agonist.
T0333 Aniracetam Aniracetam(Ro 13-5057), a nootropic and neuroprotective drug, selectively modulates the AMPA receptor and nAChR.
TN7044 S-(4-Hydroxybenzyl)glutathione L-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain gluta...
T0675 Topiramate Topiramate is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associated with hepat...
T37734 AMPA receptor modulator-2 AMPA receptor modulator-2 (Example 134) is a AMPA receptor modulator, with a pIC50 of 10.1 for TARPγ2 dependent AMPA receptor[1]. pIC50 = -lgIC50. [1]. BERRY CYN...
T7304 DNQX DNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively)
T23291 (S)-3-Hydroxyphenylglycine group I metabotropic glutamate receptors agonist
T4113 NBQX Potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo.
T7706 LY-404187 LY404187 is a positive allosteric modulator of AMPA receptors
T8435 YM90K YM90K hydrochloride is an antagonist of AMPA receptor.
T23514 VU-1545 VU 1545 is mGlu5 positive allosteric modulator.
T0326L L-Glutamine L-glutamine, a non-essential amino acid, is synthesized from glutamic acid and ammonia.
T21995 XAP044 XAP044 is a mGlu7-selective antagonist which inhibits lateral amygdala long term potentiation (LTP) in brain slices from wild type mice with a half-maximal block...
T2053 ADX-47273 ADX-47273 is a positive and selective allosteric modulator for the metabotropic glutamate receptor subtype mGluR5(EC50=170 nM).
T23515 VU-29 VU-29 is a positive allosteric mGlu5 receptor modulator with EC50=9 nM and Ki=244 nM for rmGluR5. It is selective for mGluR5 relative to other mGluR subtypes (EC...
T2497 MPEP hydrochloride MPEP hydrochloride is an effective and highly specific non-competitive antagonist at the mGlu5 receptor subtype (IC50: 36 nM).
T22730 DL-AP3 DL-AP3 is a competitive group I metabotropic glutamate receptor antagonist and inhibitor of phosphoserine phosphatase.
T22641 CDPPB CDPPB is a modulator of mGluR5 positive allosteric(with an EC50 of 27 nM in Chinese hamster ovary cells expressing human mGluR5).
T2194 Direct Blue 1 Chicago sky blue 6B, a vesicular glutamate transporters inhibitor, attenuates methamphetamine-induced hyperactivity and behavioral sensitization in mice.
T21935L AMN082 free base AMN082 is a metabotropic glutamate receptor 7 allosteric agonist.
T21935 AMN082 AMN 082 dihydrochloride is a selective metabotropic glutamate mGlu7 receptor agonist reported to exhibit antidepressant activity.
T9021 Ro0711401 Ro0711401 is an agonist of mGlu1 receptor.
T8862 ML 254 ML254 competitively interacts with the MPEP allosteric binding site. ML254 is highly selective for mGlu5 versus other mGlu receptors, has a clean ancillary Ricer...
T8626 4-oxo-1,4-dihydroquinoline-2-carboxylic acid 4-oxo-1,4-dihydroquinoline-2-carboxylic acid is a GluR and NMDA inhibitor.
T8779 HBT1 HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neurons....
T8434 SIB-1757 SIB-1757 is a selective antagonist of mGlu5 metabotropic glutamate receptor subtype (hmGlu5, IC50 : 0.4 μM)
VU0360172
T29126
VU0360172 是 mGlu5 受体的正变构调节剂(EC50 = 16 nM;Ki = 195 nM)。
MMPIP hydrochloride
T23008L
MMPIP hydrochloride 是变构 mGluR7 的选择性拮抗剂。 MMPIP hydrochloride 可用于研究 mGluR7 对中枢神经系统功能的作用。
Caroverine hydrochloride
T9133
Caroverine HCL is a potent, competitive and reversible antagonist of NMDA and AMPA glutamate receptor. It is also an antioxidant and calcium-blocking agent that ...
L-Cysteic acid monohydrate
T5083
L-Cysteic acid is an oxidation product of L-cysteine that may be used as a competitive inhibitor of the bacterial aspartate: alanine antiporter (AspT) exchange o...
CNQX
T7178
CNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively)
Decanoic Acid
T3379
Decanoic Acid acts as a non-competitive AMPA receptor antagonist.
NS 1209
T4009
NS1209 is a AMPA receptor antagonist.
Memantine hydrochloride
T1443
Memantine hydrochloride is an AMANTADINE derivative that has some dopaminergic effects. Memantine hydrochloride has been proposed as an antiparkinson agent.
Piracetam
T0426
Piracetam, a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), is used in therapy of the extensive cognitive disorders.
Org-26576
T16402
Org-26576 is a positive allosteric modulator of the AMPA receptor.
(RS)-3-Hydroxyphenylglycine
T23259
PI-linked metabotropic glutamate receptors agonist
Farampator
T3957
Farampator (CX-691;Org24448) is an AMPA receptor positive modulator.
CX516
T1884
Ampalex (Ampakine CX516; CX516; BDP 12), an ampakine and nootropic, acts as an AMPA receptor positive allosteric modulator as a therapy for Alzheimer's disease, ...
L-Glutamic acid monosodium salt
T6871
L-Glutamic acid monosodium salt (Monosodium glutamate) is an activator of mGlu1 receptor.
Talampanel
T16977
Talampanel is an orally and selective α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor antagonist with anti-seizure activity. Talampanel attenuates cas...
O-Phospho-L-serine
T1324
Phosphoserine is the phosphoric acid ester of serine.
1-BCP
T7579
1-BCP is a centrally active drug that modulates AMPA receptor gated currents.
Citric acid trilithium salt tetrahydrate
T0256
Lithium Citrate, the active component of Lithium, is a medicine used in the therapy of psychiatric disease. It has shown the effects of signaling pathways and me...
Urethane
T0051
Urethane was an antineoplastic agent .Now is used for other medicinal purposes.
Latrepirdine dihydrochloride
T6562
Latrepirdine is an orally active, and neuroactive antagonist of multiple drug targets, including histamine receptors, GluR, and 5-HT receptors, used as an antihi...
Xanthurenic Acid
T3010
Xanthurenic acid, a molecule arising from tryptophan metabolism by transamination of 3-hydroxykynurenine, activates mGlu2/3 Metabotropic glutamate receptors (mGl...
D-glutamine
T6468
D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.
CX614
T19698
CX614 is a positive allosteric modulator of the AMPA receptor with respect to AMPA.
Harmine hydrochloride
T2811
Harmine hydrochloride is extracted from Peganum Harmala Genus.
cis-PDA
T20571
cis-PDA, a general ionotropic receptor antagonist, acts by blocking NMDA, AMPA, and kainate mediated responses. It also acts as a partial NMDA receptor agonist.
Aniracetam
T0333
Aniracetam(Ro 13-5057), a nootropic and neuroprotective drug, selectively modulates the AMPA receptor and nAChR.
S-(4-Hydroxybenzyl)glutathione
TN7044
L-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glut...
Topiramate
T0675
Topiramate is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associated with hepat...
AMPA receptor modulator-2
T37734
AMPA receptor modulator-2 (Example 134) is a AMPA receptor modulator, with a pIC50 of 10.1 for TARPγ2 dependent AMPA receptor[1]. pIC50 = -lgIC50. [1]. BERRY CY...
DNQX
T7304
DNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively)
(S)-3-Hydroxyphenylglycine
T23291
group I metabotropic glutamate receptors agonist
NBQX
T4113
Potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo.
LY-404187
T7706
LY404187 is a positive allosteric modulator of AMPA receptors
YM90K
T8435
YM90K hydrochloride is an antagonist of AMPA receptor.
VU-1545
T23514
VU 1545 is mGlu5 positive allosteric modulator.
L-Glutamine
T0326L
L-glutamine, a non-essential amino acid, is synthesized from glutamic acid and ammonia.
XAP044
T21995
XAP044 is a mGlu7-selective antagonist which inhibits lateral amygdala long term potentiation (LTP) in brain slices from wild type mice with a half-maximal block...
ADX-47273
T2053
ADX-47273 is a positive and selective allosteric modulator for the metabotropic glutamate receptor subtype mGluR5(EC50=170 nM).
VU-29
T23515
VU-29 is a positive allosteric mGlu5 receptor modulator with EC50=9 nM and Ki=244 nM for rmGluR5. It is selective for mGluR5 relative to other mGluR subtypes (EC...
MPEP hydrochloride
T2497
MPEP hydrochloride is an effective and highly specific non-competitive antagonist at the mGlu5 receptor subtype (IC50: 36 nM).
DL-AP3
T22730
DL-AP3 is a competitive group I metabotropic glutamate receptor antagonist and inhibitor of phosphoserine phosphatase.
CDPPB
T22641
CDPPB is a modulator of mGluR5 positive allosteric(with an EC50 of 27 nM in Chinese hamster ovary cells expressing human mGluR5).
Direct Blue 1
T2194
Chicago sky blue 6B, a vesicular glutamate transporters inhibitor, attenuates methamphetamine-induced hyperactivity and behavioral sensitization in mice.
AMN082 free base
T21935L
AMN082 is a metabotropic glutamate receptor 7 allosteric agonist.
AMN082
T21935
AMN 082 dihydrochloride is a selective metabotropic glutamate mGlu7 receptor agonist reported to exhibit antidepressant activity.
Ro0711401
T9021
Ro0711401 is an agonist of mGlu1 receptor.
ML 254
T8862
ML254 competitively interacts with the MPEP allosteric binding site. ML254 is highly selective for mGlu5 versus other mGlu receptors, has a clean ancillary Ricer...
4-oxo-1,4-dihydroquinoline-2-carboxylic acid
T8626
4-oxo-1,4-dihydroquinoline-2-carboxylic acid is a GluR and NMDA inhibitor.
HBT1
T8779
HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neurons....
SIB-1757
T8434
SIB-1757 is a selective antagonist of mGlu5 metabotropic glutamate receptor subtype (hmGlu5, IC50 : 0.4 μM)
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