Home Tools
Log in
Cart

COX

Cyclooxygenase (COX), officially known as prostaglandin-endoperoxide synthase (PTGS), is an enzyme (specifically, a family of isozymes) that is responsible for formation of prostanoids, including thromboxane and prostaglandins such as prostacyclin, from arachidonic acid. A member of the animal-type heme peroxidase family, it is also known as prostaglandin G/H synthase.
Cat No. product name
T16169 N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride 是胰蛋白酶样蛋白酶的抑制剂。 N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride 对 IFN-γ 活性具有抑制作用。
T7081 CCCP CCCP inhibits activation of STING and its downstream signalling molecules, TBK1 and IRF3. CCCP inhibits STING-mediated IFN-β production via disrupting mitochondr...
T22790 FR 122047 hydrochloride cyclooxygenase-1 inhibitor
T0826 Meloxicam Meloxicam is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of meloxicam is as a Cyclooxygenase Inhibitor. The chemical classification of meloxic...
T0877 Gallic acid Gallic acid is found in almost all plants. Plants known for their high gallic acid content include gallnuts,grapes,tea,hops and oak bark.
T2S0618 β-Elemonic Acid 1. Beta-Elemonic acid exhibits anti-inflammatory effects. 2. Beta-Elemonic acid inhibits proliferation by inducing hypoploid cells and cell apoptosis, the antica...
T19672 Amtolmetin guacil Amtolmetin guacil is a non-acidic prodrug of tolmetin, having similar NSAID properties like tolmetin with additional analgesic, antipyretic, and gastroprotective...
T0498 Salsalate Salsalate is an orally available salicylate and non-steroidal anti-inflammatory drug (NSAID), with anti-inflammatory, analgesic and antipyretic activities.
T0432 Diclofenac diethylamine Diclofenac Diethylamine, a non-selective COX inhibitor, is utilized as a nonsteroidal anti-inflammatory drug (NSAID).
T5727 CAFESTOL CAFESTOL is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells....
TC0036 Lup-20(29)-en-3-yl acetate Lupeol acetate, a derivative of Lupeol, inhibits the progression of rheumatoid arthritis by downregulating TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B.
T8255 (±)-Catechin (±)-Catechin hydrate is a natural product,has antioxidant activity and is effective in reducing oxidative stress.
T7540 2,5-Di-tert-butylhydroquinone BHQ is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.
T1296 4-Aminosalicylic acid Aminosalicylic Acid is an analog of para-aminobenzoic acid (PABA) with antitubercular activity.
T6S0413 Pectolinarigenin 1. Pectolinarigenin exhibits hepatoprotective activity mainly via SOD antioxidant mechanism. 2. Pectolinarigenin possesses anti-inflammatory activity and that th...
T1867 Otenaproxesul ATB-346 is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity.
T1555 Diclofenac sodium Diclofenac sodium is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
T0291 Flurbiprofen Flurbiprofen is an anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal dise...
T2732 (-)-Epicatechin gallate One of the catechin isomers and a potent antioxidant that can modulate a wide range of membrane proteins. Its bilayer-modifying potency was tested using gramicid...
T0196 Diclofenac Diclofenac is a nonsteroidal benzeneacetic acid derivative with anti-inflammatory activity. Diclofenac binds and chelates both isoforms of cyclooxygenase (COX-1 ...
T8656 CAY10404 CAY10404 is a potent and highly selective inhibitor of COX-2 and COX-1. It is also a potent inhibitor of PKB/Akt and MAPK signalling pathways and induces apoptos...
T6687 Suprofen Suprofen is an IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic.
T0858 Flufenamic acid Flufenamic acid is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorder...
T0335 Sodium salicylate Sodium salicylate, a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress.
T5681 ETHYL CAFFEATE In vitro, ECF suppressed the differentiation of naive CD4+ T cells into Th1. Furthermore, ECF intensely blocked the transcriptional expression in interferon-γ-re...
T1582 Naproxen Naproxen is a propionic acid derivative and a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities.
T6S1487 Ginsenoside Rg5 1. Ginsenoside Rg5 could be a beneficial agent for the treatment of Alzheimer's disease. 2. Ginsenoside Rg5 suppresses LPS-induced nitric oxide (NO) production a...
T12933 SM-276001 SM-276001 is a potent selective agonist of TLR7,and is an orally active interferon (IFN) inducer.
T0808 Diflunisal Diflunisal is a cyclooxygenase (COX) Inhibitor, used as an anti-inflammatory analgesic.
T0424 Bismuth Subsalicylate Bismuth subsalicylate is the active ingredient in the popular medication Pepto-Bismol that is used to treat nausea, heartburn, indigestion, upset stomach, diarrh...
TN1100 Nepodin Nepodin has antimalarial, and anti-inflammatory activities, it shows significant cyclooxygenase (COX) inhibitory activity. Nepodin has an antidiabetic effect, wh...
T0646 5-Aminosalicylic Acid Mesalamine is an anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the acti...
T0477 Zileuton Zileuton is a synthetic derivative of hydroxyurea with antiasthmatic properties. The leukotriene inhibitor zileuton blocks 5-lipoxygenase, which catalyzes the fo...
TQ0180 Chebulagic acid Chebulagic acid, isolated from the Terminalia chebula Retz, is a COX-LOX dual inhibitor.
TN1660 Ganoderic acid C1 Ganoderic acid C1 has anti-inflammatory activity, has potential for treating TNF-α± mediated inflammation in asthma and other inflammatory diseases. Ganoderic ac...
TQ0288 Hexahydrocurcumin Hexahydrocurcumin is a selective, orally active COX-2 inhibitor and inactive against COX-1.
T0260 Meclofenamic acid sodium Meclofenamate Sodium, a non-steroidal anti-inflammatory agent, has properties of antipyretic and antigranulation activities. It also inhibits prostaglandin biosy...
T30937 Cimicoxib Cimicoxib (UR-8880) is a non-steroidal anti-inflammatory drug (NSAID), which is also a COX-2 inhibitor, used in veterinary medicine to treat pain and inflammatio...
T8236 RHC 80267 RHC 80267 is a selective inhibitor of DAGL (IC50 : 4 µM in canine platelets)
TN1377 α-Spinasterol α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects. α...
T12580 PTUPB PTUPB is a potent and dual inhibitor of sEH and COX-2 enzymes(IC50 of 0.9 nM and 1.26 μM, respectively).
T3981 Acacetin Acacetin is an O-methylated flavone found in various plants, shows antinociceptive, anti-inflammatory, and antioxidant activity in various research models.
T4643 TFAP TFAP is a selective cyclooxygenase-1 (COX-1) inhibitor
T5431 [10]-Shogaol 10-Shogaol is an extract from ginger displaying antioxidant activity. It also may contain hypolipidemic and insulin-sensitizing effects.
T3877 Esculentoside A Esculentoside A can suppress inflammatory responses in LPS-induced ALI through inhibition of the NF-κB and mitogen-activated protein kinase signaling pathways. E...
T0825 Ebselen Ebselen is a organoselenium compound with anti-inflammatory, anti-oxidant and cytoprotective activity. Ebselen acts as a glutathione peroxidase mimetic and is th...
T8293 γ-Tocopherol (+)-γ-Tocopherol is one of the naturally occurring forms of Vitamin E. It is the most abundant Tocopherol in soybean and corn oils.
T2230 Paeoniflorin Paeoniflorin is a herbal constituent extracted from the root of Paeonia albiflora Pall.
T7030 Anemarsaponin B Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activity,...
T4561 Tiaprofenic acid Tiaprofenic acid is a non-steroidal anti-inflammatory drug used to treat pain, especially arthritic pain.
N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride
T16169
N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride 是胰蛋白酶样蛋白酶的抑制剂。 N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride 对 ...
CCCP
T7081
CCCP inhibits activation of STING and its downstream signalling molecules, TBK1 and IRF3. CCCP inhibits STING-mediated IFN-β production via disrupting mitochond...
FR 122047 hydrochloride
T22790
cyclooxygenase-1 inhibitor
Meloxicam
T0826
Meloxicam is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of meloxicam is as a Cyclooxygenase Inhibitor. The chemical classification of meloxic...
Gallic acid
T0877
Gallic acid is found in almost all plants. Plants known for their high gallic acid content include gallnuts,grapes,tea,hops and oak bark.
β-Elemonic Acid
T2S0618
1. Beta-Elemonic acid exhibits anti-inflammatory effects. 2. Beta-Elemonic acid inhibits proliferation by inducing hypoploid cells and cell apoptosis, the antica...
Amtolmetin guacil
T19672
Amtolmetin guacil is a non-acidic prodrug of tolmetin, having similar NSAID properties like tolmetin with additional analgesic, antipyretic, and gastroprotective...
Salsalate
T0498
Salsalate is an orally available salicylate and non-steroidal anti-inflammatory drug (NSAID), with anti-inflammatory, analgesic and antipyretic activities.
Diclofenac diethylamine
T0432
Diclofenac Diethylamine, a non-selective COX inhibitor, is utilized as a nonsteroidal anti-inflammatory drug (NSAID).
CAFESTOL
T5727
CAFESTOL is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells....
Lup-20(29)-en-3-yl acetate
TC0036
Lupeol acetate, a derivative of Lupeol, inhibits the progression of rheumatoid arthritis by downregulating TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B.
(±)-Catechin
T8255
(±)-Catechin hydrate is a natural product,has antioxidant activity and is effective in reducing oxidative stress.
2,5-Di-tert-butylhydroquinone
T7540
BHQ is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.
4-Aminosalicylic acid
T1296
Aminosalicylic Acid is an analog of para-aminobenzoic acid (PABA) with antitubercular activity.
Pectolinarigenin
T6S0413
1. Pectolinarigenin exhibits hepatoprotective activity mainly via SOD antioxidant mechanism. 2. Pectolinarigenin possesses anti-inflammatory activity and that th...
Otenaproxesul
T1867
ATB-346 is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity.
Diclofenac sodium
T1555
Diclofenac sodium is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
Flurbiprofen
T0291
Flurbiprofen is an anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal dise...
(-)-Epicatechin gallate
T2732
One of the catechin isomers and a potent antioxidant that can modulate a wide range of membrane proteins. Its bilayer-modifying potency was tested using gramicid...
Diclofenac
T0196
Diclofenac is a nonsteroidal benzeneacetic acid derivative with anti-inflammatory activity. Diclofenac binds and chelates both isoforms of cyclooxygenase (COX-1 ...
CAY10404
T8656
CAY10404 is a potent and highly selective inhibitor of COX-2 and COX-1. It is also a potent inhibitor of PKB/Akt and MAPK signalling pathways and induces apoptos...
Suprofen
T6687
Suprofen is an IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic.
Flufenamic acid
T0858
Flufenamic acid is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorder...
Sodium salicylate
T0335
Sodium salicylate, a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress.
ETHYL CAFFEATE
T5681
In vitro, ECF suppressed the differentiation of naive CD4+ T cells into Th1. Furthermore, ECF intensely blocked the transcriptional expression in interferon-γ-r...
Naproxen
T1582
Naproxen is a propionic acid derivative and a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities.
Ginsenoside Rg5
T6S1487
1. Ginsenoside Rg5 could be a beneficial agent for the treatment of Alzheimer's disease. 2. Ginsenoside Rg5 suppresses LPS-induced nitric oxide (NO) production a...
SM-276001
T12933
SM-276001 is a potent selective agonist of TLR7,and is an orally active interferon (IFN) inducer.
Diflunisal
T0808
Diflunisal is a cyclooxygenase (COX) Inhibitor, used as an anti-inflammatory analgesic.
Bismuth Subsalicylate
T0424
Bismuth subsalicylate is the active ingredient in the popular medication Pepto-Bismol that is used to treat nausea, heartburn, indigestion, upset stomach, diarrh...
Nepodin
TN1100
Nepodin has antimalarial, and anti-inflammatory activities, it shows significant cyclooxygenase (COX) inhibitory activity. Nepodin has an antidiabetic effect, wh...
5-Aminosalicylic Acid
T0646
Mesalamine is an anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the acti...
Zileuton
T0477
Zileuton is a synthetic derivative of hydroxyurea with antiasthmatic properties. The leukotriene inhibitor zileuton blocks 5-lipoxygenase, which catalyzes the fo...
Chebulagic acid
TQ0180
Chebulagic acid, isolated from the Terminalia chebula Retz, is a COX-LOX dual inhibitor.
Ganoderic acid C1
TN1660
Ganoderic acid C1 has anti-inflammatory activity, has potential for treating TNF-α± mediated inflammation in asthma and other inflammatory diseases. Ganoderic ...
Hexahydrocurcumin
TQ0288
Hexahydrocurcumin is a selective, orally active COX-2 inhibitor and inactive against COX-1.
Meclofenamic acid sodium
T0260
Meclofenamate Sodium, a non-steroidal anti-inflammatory agent, has properties of antipyretic and antigranulation activities. It also inhibits prostaglandin biosy...
Cimicoxib
T30937
Cimicoxib (UR-8880) is a non-steroidal anti-inflammatory drug (NSAID), which is also a COX-2 inhibitor, used in veterinary medicine to treat pain and inflammatio...
RHC 80267
T8236
RHC 80267 is a selective inhibitor of DAGL (IC50 : 4 µM in canine platelets)
α-Spinasterol
TN1377
α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects. ...
PTUPB
T12580
PTUPB is a potent and dual inhibitor of sEH and COX-2 enzymes(IC50 of 0.9 nM and 1.26 μM, respectively).
Acacetin
T3981
Acacetin is an O-methylated flavone found in various plants, shows antinociceptive, anti-inflammatory, and antioxidant activity in various research models.
TFAP
T4643
TFAP is a selective cyclooxygenase-1 (COX-1) inhibitor
[10]-Shogaol
T5431
10-Shogaol is an extract from ginger displaying antioxidant activity. It also may contain hypolipidemic and insulin-sensitizing effects.
Esculentoside A
T3877
Esculentoside A can suppress inflammatory responses in LPS-induced ALI through inhibition of the NF-κB and mitogen-activated protein kinase signaling pathways. ...
Ebselen
T0825
Ebselen is a organoselenium compound with anti-inflammatory, anti-oxidant and cytoprotective activity. Ebselen acts as a glutathione peroxidase mimetic and is th...
γ-Tocopherol
T8293
(+)-γ-Tocopherol is one of the naturally occurring forms of Vitamin E. It is the most abundant Tocopherol in soybean and corn oils.
Paeoniflorin
T2230
Paeoniflorin is a herbal constituent extracted from the root of Paeonia albiflora Pall.
anemarsaponin B
T7030
Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activity...
Tiaprofenic acid
T4561
Tiaprofenic acid is a non-steroidal anti-inflammatory drug used to treat pain, especially arthritic pain.
1 2 3 4 5 6 7 8