TN4860 |
Pueroside B
|
100692-54-4
|
98%
|
|
Pueroside B may can treat coronary heart disease, it can interact with two or more targets[peroxisome proliferator activated receptor γ (PPAR-γ), angiotensin-con...
|
T4S1616 |
Sanggenon D
|
81422-93-7
|
98%
|
|
Sanggenone D represents a new scaffold of positive GABAA receptor modulators, it also inhibits COX-2 activity (IC 50 = 73-100 μM). Sanggenone D has anti-inflamma...
|
TN5011 |
Shizukaol B
|
142279-40-1
|
98%
|
|
Shizukaol B exerts anti-inflammatory effects in LPS-activated microglia partly by modulating JNK-AP-1 signaling pathway; it also shows significant anti-neuroinfl...
|
T16817 |
S-2474
|
158089-95-3
|
98%
|
|
S-2474 is an inhibitor of COX-2 and 5-lipoxygenase (IC50s: 11 nM and 27 μM for COX-2 and COX-1 in human intact cells).
|
T22346 |
Indomethacin sodium hydrate
|
74252-25-8
|
98%
|
|
Indomethacin Sodium is the sodium salt of indomethacin, which is a non-selective, competitive, and reversible, inhibitor of cyclooxygenases 1 and 2 with analgesi...
|
T16419 |
Oxyphenbutazone
|
129-20-4
|
98%
|
|
Oxyphenbutazone is a non-selective COX inhibitor. Oxyphenbutazone is a phenylbutazone derivative. It has an anti-inflammatory effect. Oxyphenbutazone selectively...
|
TN1755 |
Hyperforin
|
11079-53-1
|
98%
|
|
Hyperforin acts as an angiogenesis inhibitor, it as a possible antidepressant component of hypericum extracts.
|
TN1581 |
Dihydroguaiaretic acid
|
66322-34-7
|
98%
|
|
Dihydroguaiaretic acid has antioxidative activity, can significantly protect primary cultured neuronal cells against glutamate-induced oxidative stress.
|
TN3708 |
Coronarin D
|
119188-37-3
|
98%
|
|
Coronarin D shows promising antifungal activity against C. albicans in vitro, the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration...
|
TN3922 |
Effusanin E
|
76470-15-0
|
98%
|
|
Effusanin E shows antibacterial and anti-cancer activities, it significantly inhibits cell proliferation and induces apoptosis in NPC cells by suppressing p50/p6...
|
T13160 |
Timegadine
|
71079-19-1
|
98%
|
|
Timegadine is a competitive inhibitor of COX and lipo-oxygenase, with IC50s ranging from 5 nM (washed rabbit platelets) to 20 μM (rat brain) for COX and 100 μM f...
|
T16464 |
Pelubiprofen
|
69956-77-0
|
98%
|
|
Pelubiprofen inhibits COX activity and the transforming growth factor-β activated kinase 1-IκB kinase β-NF-κB pathway. It also has significant anti-inflammatory ...
|
TN3070 |
4beta-Hydroxywithanolide E
|
54334-04-2
|
98%
|
|
4beta-Hydroxywithanolide E(4bHWE) can inhibit the growth of colon cancer monolayer and spheroid cultures, it assert its anti-tumor activity in carcinogenic progr...
|
T15630 |
Tilmacoxib
|
180200-68-4
|
98%
|
|
Tilmacoxib is a highly selective, time-dependent, and irreversible inhibitor of human COX-2 ( IC50: 85 nM in an enzyme assay).
|
T13263 |
COX/5-LO-IN-1
|
154355-75-6
|
98%
|
|
COX/5-LO-IN-1 is a cyclooxygenase and 5-lipoxygenase (5-LO) inhibitor, and used for inflammatory and allergic disease states.
|
TN4307 |
Isolimonexic acid
|
73904-93-5
|
98%
|
|
Isolimonexic acid exhibits cytotoxicity on MCF-7 cell lines, it also inhibits Panc-28 cancer cell growth.
|
TN4648 |
Nepetoidin B
|
55486-06-1
|
98%
|
|
Nepetoidin B has anti-fungal, anti-bacterial, and antiinflammatory effects, it can inhibit LPS-stimulated NO production possibly via modulation of iNOS mediated ...
|
TN4586 |
Mulberrofuran A
|
68978-04-1
|
98%
|
|
Mulberrofuran A can inhibit the formations of 12-hydroxy-, 8, 10-heptadecatrienoic acid (HHT) and thromboxane B2, but it can increase the formation of 12-hydroxy...
|
TN4659 |
Nimbin
|
5945-86-8
|
98%
|
|
Nimbin is an anti-pyretic, can be used to treat arthritis, hypoglycaemia, peptic ulcers, anti-secretory activity, and it can also be used as an antibiotic. Nimbi...
|
T12860 |
SC57666
|
158959-32-1
|
98%
|
|
SC57666 is a selective inhibitor of COX2(IC50 of 26 nM).
|