Potassium Channel

Potassium Channels. K+ channels are membrane proteins that allow rapid and selective flow of K+ ions across the cell membrane, and thus generate electrical signals in cells. Voltage-gated K+ channels (Kv channels), present in all animal cells, open and close upon changes in the transmembrane potential.

Cat. No.	Product name	CAS No.	Purity
TN4638	Neolinine	112515-37-4	98%
TN4638	Neolinine(at 10uM) shows significant hERG K+ channel inhibition activity.
TN5060	Stauntosaponin A	1417887-91-2	98%
TN5060	Stauntosaponin A and stauntosaponin B show moderate inhibitory activities against Na+/K+-ATPase with IC50 values of 21 and 29 uM, respectively.
TN1367	Alismol	87827-55-2	98%
TN1367	Alismol has antihypertensive action, it decreases cardiac output, heart rate and left ventricular pressure, but it increases coronary flow, it has been used for ...
T2434	LY 303511	154447-38-8	98%
T2434	LY303511, an inactive analogue of LY294002, is a mTOR inhibitor and no inhibition for PI3-K.
T14666	BL-1249	18200-13-0	98%
T14666	BL-1249 is a nonsteroidal anti-inflammatory drug (NSAID) and a potassium channel activator. BL-1249 exhibits more selective for the bladder (EC50 of 1.26 μM) tha...
TN2306	Wilfordine	37239-51-3	98%
TN2306	Wilfordine is an insecticidally active alkaloid, Na+-K+-ATPase may be an acting target of wilfordine against some larvae of insect.
TMA0805	Lupanine	550-90-3	98%
TMA0805	Lupanine has a weak sedative effect on the central nervous system, interaction with specific drugs used for treatment of the CNS and for analgesic activity. Lupa...
TN4303	Isokaempferide	1592-70-7	98%
TN4303	Isokaempferide shows hepatoprotective, antiproliferative, and anti-inflammatory effects, the anti-inflammatory effects can be explained, at least in part, by red...
TN1588	Dihydroisotanshinone I	20958-18-3	98%
TN1588	Dihydroisotanshinone I has protective action against menadione-induced hepatotoxicity, attributed to its antioxidant properties including the free radical scaven...
TN2918	3-Acetoxy-8(17),13E-labdadien-15-oic acid	63399-37-1	98%
TN2918	ent-3-Acetoxy-labda-8(17),13-dien-15-oic acid have vasorelaxant and hypotensive actions, the mechanisms underlying the cardiovascular actions of the labdane invo...
T11753	Keto Ziprasidone	884305-07-1	98%
T11753	Ziprasidone, an antipsychotic agent, is a combined 5-HT (serotonin) and dopamine receptor antagonist. Keto Ziprasidone is an impurity of Ziprasidone.
T14189	Almokalant	123955-10-2	98%
T14189	Almokalant is a class III antiarrhythmic drug, acts as a potassium channel blocker. And it inhibits a specific component (Ikr) of the time-dependent delayed rect...
T6827	Endoxifen Z-isomer hydrochloride	1032008-74-4	98%
T6827	Endoxifen HCl is the active metabolite of Tamoxifen, which is an effective and selective estrogen receptor antagonist.
TN4322	Isopulegol	7786-67-6	98%
TN4322	Isopulegol presents depressant- and anxiolytic-like effects, it also has anticonvulsant and bioprotective effects against PTZ-induced convulsions are possibly re...
T16285	Neosolaniol	36519-25-2	98%
T16285	Neosolaniol evokes a robust anorectic response. Neosolaniol is a type A trichothecene mycotoxin from Fusarium sp.
TN3379	β-Allocryptopine	24240-04-8	98%
TN3379	Allocryptopine has certain effects on anti-injury for hepatocyte, ameliorating liver function, and prohibiting hepatic fibrosis; it increases mRNA levels of cyto...
TN3636	Chlorahololide C	1007859-25-7	98%
TN3636	Chlorahololide C is a potent and selective potassium channel blocker, it exerts potent and selective inhibition on the delayed rectifier (I(K)) K(+) current with...
TN4697	Odoroside H	18810-25-8	98%
TN4697	Odoroside H has anticancer activities, the cytotoxic effects are induced by the inhibition of the plasma membrane bound Na(+)/K(+)-ATPase.
T14040	4-Hydroxytolbutamide	5719-85-7	98%
T14040	4-Hydroxytolbutamide(Hydroxytolbutamide), a metabolite of Tolbutamide, which is metabolized by CYP2C8 and CYP2C9. Tolbutamide is a first generation potassium cha...
TQ0307	Vernakalant	794466-70-9	98%
TQ0307	Vernakalant (RSD-1235) is a mixed ion channel blocker.