Search Result

Search Results for " reductase "

Targets

Reductase HMG-CoA Reductase Glutathione reductase Others

372

Compounds

Natural Products

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
TP1604L	Thioredoxin reductase peptide acetate	Thioredoxin reductase peptide acetate(950890-23-0 free base)	Others
	Thioredoxin reductase peptide acetate corresponds to residues 53–67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research.Mammalian thioredoxin reductase (TR) catalyzes the reduction of the redox-active...		Others
T14175	Aldose reductase-IN-1	AT-001,Caficrestat	Others , Reductase
	Aldose reductase-IN-1 (AT-001) is a aldose reductase inhibitor (IC50: 28.9 pM).		Others , Reductase
T78342	Glutathione reductase	EC 1.6.4.2
	Glutathione reductase (EC 1.6.4.2) is an enzyme that ensures the availability of reduced glutathione [1].
TP1604	Thioredoxin reductase peptide
	Thioredoxin reductase peptide corresponds to residues 53–67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research.Mammalian thioredoxin reductase (TR) catalyzes the reduction of the redox-active disulfi...
T10636	5α-reductase-IN-1		Others
	5α-reductase-IN-1 is a potent inhibitor of the enzyme 5α-reductase. This compound is primarily employed in research studies to investigate its potential efficacy in treating patterned alopecia. It is commonly used in com...		Others
TP1375	Thioredoxin reductase peptide TFA
	Thioredoxin reductase peptide TFA corresponds to residues 53-67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research..
T80057	Cytochrome P450 reductase
	Cytochrome P450 reductase, a NADPH-cytochrome reductase, facilitates an optimal conformation of aromatase for substrate binding [1].
T61957	Aldose reductase-IN-3
	Aldose reductase-IN-3 (Compound 5) is an effective and moderately selective aldose reductase (AR) inhibitor (IC50=3.99 μ M). Aldose reductase is a molecular target involved in various inflammatory diseases (including sep...
T60601	Aldose reductase-IN-4
	Aldose reductase-IN-4 (compund IIc) is an inhibitor of aldose reductase with IC50s of 11.70 μM and 0.98 μM for ALR1 and ALR2, respectively [1].
T61555	Aldose reductase-IN-6
	Aldose reductase-IN-6 (Compound 3) is a competitive inhibitor of aldose reductase (AR), possessing an IC50 of 3.164 μM and a Ki of 0.018 μM. Notably, Aldose reductase-IN-6 demonstrates no cytotoxicity toward normal cells...
T60897	Aldose reductase-IN-5
	Aldose reductase-IN-5 is an inhibitor of aldose reductase (ALR2) that enhances the combination of inhibitory excitability and antioxidant capacity, thereby delaying the diabetes complications progress.
T62951	Aldose reductase-IN-2
	Aldose reductase-IN-2 (Compound 5f) is a potent inhibitor of aldose reductase (AR) with antioxidant properties. aldose reductase-IN-2 is a promising anti-diabetic complication drug.
T79520	HMG-CoA Reductase-IN-1
	HMG-CoA Reductase-IN-1 is an inhibitor of HMG-CoA reductase, demonstrating strong inhibitory activity on HMGR and affinity for OATP1B1, with pIC50 and pKm values of 8.54 and 1.98, respectively. It is utilized in hypercho...
T16910	Sorbinil		Reductase
	Sorbinil is an Aldose reductase inhibitor. Sorbinil plays a therapeutic role in treating diabetes and diabetic complications decreases AR activity and inhibit the polyol pathway.		Reductase
T22757	EBPC		Reductase
	EBPC is an inhibitor of aldose reductase.		Reductase
T23403	Sulindac sulfone		Reductase , COX
	Sulindac sulfone is a metabolite of the nonsteroidal anti-inflammatory drug sulindac.		Reductase , COX
T14342	Atorvastatin lactone		HMG-CoA Reductase
	Atorvastatin lactone is a prodrug form of atorvastatin. Which is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor.		HMG-CoA Reductase
T10393	AT-007		Reductase
	AT-007 is an orally active CNS penetrant Aldose Reductase inhibitor for the treatment of Galactosemia (IC50: 100 pM). It reduces toxic galactitol levels and prevents disease complications in GALT deficiency rats.		Reductase
T0488	Finasteride	MK-906	Reductase
	Finasteride (MK-906) is an oral inhibitor of active testosterone 5-alpha-reductase and Ki value is 10 nM.		Reductase
T1499	Dutasteride	GG 745,Avodart,GI 198745	Apoptosis , Reductase
	Dutasteride (GI 198745) is a 5-alpha-reductase inhibitor that inhibits both type-1 and type2 isoforms of the enzyme and is used to treat benign prostatic hyperplasia.		Apoptosis , Reductase
T5481	TRi-1		Others
	TRi-1 is irreversible inhibitor of cytosolic thioredoxin reductase 1 (TXNRD1), with an IC50 of 12 nM. TRi-1 has little mitochondrial toxicity for anticancer therapy		Others
T6901	N6022		GSNOR
	N6022(IC50 of 8 nM) is an effective, reversible, and selective S-Nitrosoglutathione reductase(GSNOR) inhibitor.		GSNOR
T36692	Fanotaprim		DHFR
	Fanotaprim is a dihydrofolate reductase (DHFR) inhibitor. Fanotaprim inhibits the growth of T. gondii strains with a TgDHFR IC50 of 1.57 ± 0.11 nM and a hDHFR IC50 of 308 ± 71 nM and a hDHFR to TgDHFR selectivity ratio o...		DHFR
T20765	Atorvastatin		HMG-CoA Reductase , Autophagy
	Atorvastatin is an orally active HMG-CoA reductase inhibitor that has the ability to effectively lower blood lipids by activating liver cytochrome p450 to accelerate metabolism. Atorvastatin inhibited proliferation and i...		HMG-CoA Reductase , Autophagy
T10339	Antitrypanosomal agent 1		Parasite
	Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor (IC50: 3.3 μM). Antitrypanosomal agent 1 inhibits glutathione reductase (IC50: 64.8 μM) and T. brucei (EC50: 1 μM).		Parasite
T2013	Ponalrestat		Reductase
	Ponalrestat is an aldose reductase inhibitor.		Reductase
T17114	Tolrestat	AY-27773	Reductase
	Tolrestat (AY-27773) is a potent inhibitor of aldose reductase (IC50 = 35 nM).		Reductase
T14362	AY 9944		Others
	AY 9944 is a specific cholesterol biosynthesis inhibitor. AY 9944 inhibits the 7-dehydro cholesterol Δ7-reductase (DHCR7) enzyme (IC50=13 nM). At high doses, AY 9944 inhibits also in cultured embryos sterol Δ7-Δ8 isomera...		Others
T5195	Alrestatin	AY-22284	Reductase
	Alrestatin (AY-22284) is a specific inhibitor of aldose reductase and attenuates glucose-induced angiotensin II production in rat vascular smooth muscle in vitro.		Reductase
T8452	Dantrolene		Others
	Dantrolene is a postsynaptic muscle relaxant by inhibiting Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors.		Others
T1458	Epalrestat	ONO2235	Reductase
	Epalrestat (ONO2235), an aldose reductase inhibitor, is well tolerated in Long-term therapy. It can effectually ameliorate the associated symptoms of diabetic neuropathy and delay the progression of the disease, particul...		Reductase
T1487	Fluvastatin sodium	XU 62320 sodium,XU-62-320,Fluvastatin sodium salt	Ferroptosis , HMG-CoA Reductase , Autophagy
	Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol lowering agent.		Ferroptosis , HMG-CoA Reductase , Autophagy
T6450	Clinofibrate	S-8527,Lipoclin	HMG-CoA Reductase , Autophagy
	Clinofibrate (Lipoclin)(IC50 of 0.47 mM), a lipid-lowering agent, inhibits hydroxymethylglutaryl coenzyme A reductase (HMGCR). It is utilized to control high cholesterol and triacylglyceride levels in the blood.		HMG-CoA Reductase , Autophagy
T22229	Acid Yellow 36	Metanil Yellow	Others
	Acid Yellow 36 (Metanil Yellow) is an azo dye and a pH indicator. Acid Yellow 36 changes its color from red at pH 1.2 to yellow at pH 2.3.		Others
T38684	AKR1C3-IN-4	AKR1C3-IN-4	NADPH
	AKR1C3-IN-4 is a potent and selective inhibitor of aldo-keto reductase 1C3 (AKR1C3) with an IC50 of 0.56 μM. AKR1C3-IN-4 has the potential for castrate resistant prostate cancer (CRPC) research.		NADPH
T0297	Clofarabine	Clofarex,Evoltra,Clolar	Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Autophagy
	Clofarabine (Clofarex)m, a second generation purine nucleoside analog with antineoplastic activity, inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase.
T14864	Caracemide	NSC-253272	Others , DNA/RNA Synthesis , Antibacterial
	Caracemide (NSC-253272) inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.		Others , DNA/RNA Synthesis , Antibacterial
T8003	Methotrexate disodium		Apoptosis , Dehydrogenase , DNA/RNA Synthesis , Antifolate
	Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor		Apoptosis , Dehydrogenase , DNA/RNA Synthesis , Antifolate
T6994	SR12813	SR-12813,SR 12813,GW 485801	HMG-CoA Reductase , Autophagy
	SR12813 (GW 485801) is a pregnane X receptor (PXR) agonist.		HMG-CoA Reductase , Autophagy
T35317	Zopolrestat	CP 73850,CP73850,CP-73850,Zopolrestatum	Reductase
	Zopolrestat (CP 73850) is a potent inhibitor of aldose reductase (IC50 = 3.1 nM).		Reductase
T3157	COH29	RNR Inhibitor COH29	DNA/RNA Synthesis
	COH29 (RNR Inhibitor COH29) is an orally available, aromatically substituted thiazole and inhibitor of the human ribonucleotide reductase (RNR), with potential antineoplastic activity. Upon oral administration, the RNR i...		DNA/RNA Synthesis
T3693	DHFR-IN-3	7-bromoquinazoline-2,4-diamine	Others
	DHFR-IN-3 (7-bromoquinazoline-2,4-diamine) is an active biochemical.		Others
T12092	Monacolin J	Antibiotic MB 530A,Lovastatin diol lactone	HMG-CoA Reductase , Autophagy
	Monacolin J (Antibiotic MB 530A) is a cholesterol biosynthesis inhibitor.		HMG-CoA Reductase , Autophagy
T15568	Imirestat	Alcon 1576,AL 1576,HOE 843	Reductase
	Imirestat (HOE 843) is an aldose reductase inhibitor that can be used in diabetes research.		Reductase
T6120	Pralatrexate	Folotyn,10-Propargyl-10-deazaaminopterin	Apoptosis , DHFR , Antifolate , TAM Receptor
	Pralatrexate (10-Propargyl-10-deazaaminopterin) is a folate analogue inhibitor of dihydrofolate reductase (DHFR) exhibiting high affinity for reduced folate carrier-1 (RFC-1) with antineoplastic and immunosuppressive act...		Apoptosis , DHFR , Antifolate , TAM Receptor
T1676	Rosuvastatin	ZD 4522	Potassium Channel , HMG-CoA Reductase , Autophagy
	Rosuvastatin (ZD 4522) is an antilipemic agent that competitively inhibits hydroxymethyl-glutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting...		Potassium Channel , HMG-CoA Reductase , Autophagy
T3116	Atorvastatin hemicalcium salt	Lipitor,Atorvastatin hemicalcium,Atorvastatin Calcium,CI-981,Sortis	Ferroptosis , HMG-CoA Reductase , Autophagy
	Atorvastatin hemicalcium salt (Atorvastatin Calcium), an effective HMG-CoA reductase inhibitor (IC50 = 8 nM), is utilized as a cholesterol-lowering medication.		Ferroptosis , HMG-CoA Reductase , Autophagy
T2534	Pitavastatin calcium	P-872441,nisvastatin,itavastatin,Pitavastatin hemicalcium,NK-104	Apoptosis , Mitophagy , Endogenous Metabolite , HMG-CoA Reductase , Autophagy
	Pitavastatin calcium (NK-104) is a potent inhibitor of HMG-CoA reductase (Ki: 1.7 nM). It lowers both total cholesterol and low-density lipoprotein cholesterol in animals and humans. Metabolism of pitavastatin by the cyt...
T1485	Methotrexate	NCI-C04671,WR19039,Amethopterin,CL14377	Apoptosis , Dehydrogenase , DNA/RNA Synthesis , Antifolate
	Methotrexate (WR19039) is a folate analog, an inhibitor of the dihydrofolate reductase DHFR. Methotrexate has antimetabolic, antitumor, and immunosuppressive activities, and is commonly used in rheumatoid arthritis and v...		Apoptosis , Dehydrogenase , DNA/RNA Synthesis , Antifolate
T20168	Aurothiomalate sodium	Myocrisin,Myocrisine,Miochrysin,Sodium aurothiomalate,Myochrysine,gold sodium thiomalate	Others , PKC
	Sodium aurothiomalate is a gold compound that is used for its immunosuppressive anti-rheumatic effects. Aurothiomalate sodium (Miochrysin) is a potent and selective inhibitor of oncogenic PKC-ι signaling. Aurothiomalate ...		Others , PKC

Compounds

Thioredoxin reductase peptide acetate

TP1604L

Synonym: Thioredoxin reductase peptide acetate(950890-23-0 free base)

Target: Others

Aldose reductase-IN-1

T14175

Synonym: AT-001,Caficrestat

Target: Others, Reductase

Glutathione reductase

T78342

Synonym: EC 1.6.4.2

Target:

Thioredoxin reductase peptide

Thioredoxin reductase peptide TFA

TP1375

Synonym:

Target:

Cytochrome P450 reductase

T80057

Synonym:

Target:

Aldose reductase-IN-3

T61957

Synonym:

Target:

Aldose reductase-IN-4

T60601

Synonym:

Target:

Aldose reductase-IN-6

T61555

Synonym:

Target:

Aldose reductase-IN-5

T60897

Synonym:

Target:

Aldose reductase-IN-2

T62951

Synonym:

Target:

HMG-CoA Reductase-IN-1

Target: Reductase, COX

Atorvastatin lactone

T14342

Synonym:

Target: HMG-CoA Reductase

Synonym: GG 745,Avodart,GI 198745

Target: Apoptosis, Reductase

Target: HMG-CoA Reductase, Autophagy

Antitrypanosomal agent 1

Synonym: XU 62320 sodium,XU-62-320,Fluvastatin sodium salt

Target: Ferroptosis, HMG-CoA Reductase, Autophagy

Clinofibrate

T6450

Synonym: S-8527,Lipoclin

Target: HMG-CoA Reductase, Autophagy

Acid Yellow 36

T22229

Synonym: Metanil Yellow

Synonym: Clofarex,Evoltra,Clolar

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, Autophagy

Caracemide

T14864

Synonym: NSC-253272

Target: Others, DNA/RNA Synthesis, Antibacterial

Methotrexate disodium

T8003

Synonym:

Target: Apoptosis, Dehydrogenase, DNA/RNA Synthesis, Antifolate

SR12813

T6994

Synonym: SR-12813,SR 12813,GW 485801

Target: HMG-CoA Reductase, Autophagy

Zopolrestat

T35317

Synonym: CP 73850,CP73850,CP-73850,Zopolrestatum

Target: Reductase

COH29

T3157

Synonym: RNR Inhibitor COH29

Target: DNA/RNA Synthesis

DHFR-IN-3

T3693

Synonym: 7-bromoquinazoline-2,4-diamine

Target: Others

Monacolin J

T12092

Synonym: Antibiotic MB 530A,Lovastatin diol lactone

Target: HMG-CoA Reductase, Autophagy

Imirestat

T15568

Synonym: Alcon 1576,AL 1576,HOE 843

Target: Reductase

Pralatrexate

T6120

Synonym: Folotyn,10-Propargyl-10-deazaaminopterin

Target: Apoptosis, DHFR, Antifolate, TAM Receptor

Rosuvastatin

T1676

Synonym: ZD 4522

Target: Potassium Channel, HMG-CoA Reductase, Autophagy

Atorvastatin hemicalcium salt

T3116

Synonym: Lipitor,Atorvastatin hemicalcium,Atorvastatin Calcium,CI-981,Sortis

Target: Ferroptosis, HMG-CoA Reductase, Autophagy

Pitavastatin calcium

T2534

Synonym: P-872441,nisvastatin,itavastatin,Pitavastatin hemicalcium,NK-104

Target: Apoptosis, Mitophagy, Endogenous Metabolite, HMG-CoA Reductase, Autophagy

Methotrexate

T1485

Synonym: NCI-C04671,WR19039,Amethopterin,CL14377

Target: Apoptosis, Dehydrogenase, DNA/RNA Synthesis, Antifolate

Aurothiomalate sodium

T20168

Synonym: Myocrisin,Myocrisine,Miochrysin,Sodium aurothiomalate,Myochrysine,gold sodium thiomalate

Target: Others, PKC

Cat No.	Product Name	Synonyms	Targets
TN2601	12-O-Methylcarnosic acid		Reductase
	12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from Salvia microphylla, is an active constituent of 5α-Reductase inhibition with an IC50 value of 61.7 μM. 12-O-Methylcarnosic acid has Antioxidant activity...		Reductase
T6S2384	Poliumoside		Reductase
	Poliumoside is a natural compound which exhibits significant inhibition of advanced glycation end product formation with IC50 value of 4.6-25.7 μM, it also exhibits great inhibitory effects on rat lens aldose reductase w...		Reductase
T8115	Menthofuran		Others
	Menthofuran is a natural product.		Others
TN1733	Hesperetin 7-O-glucoside		Anti-infection , Antibacterial , HMG-CoA Reductase
	Hesperetin 7-O-glucoside and prunin are direct precursors of naringin and neohesperidin, respectively, in C. aurantium. Hesperetin 7-O-glucoside shows inhibition of human HMG-CoA reductase, it also exhibits effective inh...		Anti-infection , Antibacterial , HMG-CoA Reductase
T3378	Alpha-Estradiol	Alfatradiol,17α-Estradiol,Epiestrol,Epiestradiol	Estrogen/progestogen Receptor , Reductase , Endogenous Metabolite
	Alpha-Estradiol (Epiestradiol) is an estrogen that inhibits 5alpha-reductase and has potential in the study of androgenetic alopecia.
TN6715	7-Ketocholesterol		Others
	7-Ketocholesterol is a metabolite of Cholesterol		Others
T5S1131	Ganoderic acid C6		Others
	1. Ganoderic acid C6 has antinociceptive activity.		Others
T1207	Lovastatin	MK-803,Mevinolin	Ferroptosis , HMG-CoA Reductase , Autophagy
	Lovastatin (MK-803) is an HMG-CoA Reductase Inhibitor, used for lowering cholesterol.		Ferroptosis , HMG-CoA Reductase , Autophagy
T0683	Mevastatin	Compactin,ML236B	Apoptosis , Antibacterial , Antibiotic , HMG-CoA Reductase , Autophagy , Lipid
	Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum. Mevastatin was the first statin to enter clinical trials.
T1664	Meglutol	Dicrotalic acid,3-Hydroxy-3-methylglutaric acid	Endogenous Metabolite , HMG-CoA Reductase , Autophagy
	Meglutol (3-Hydroxy-3-methylglutaric acid) is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conve...		Endogenous Metabolite , HMG-CoA Reductase , Autophagy
T0725	Isoliquiritigenin	ISL,Isoliquiritigen,GU17	Apoptosis , Influenza Virus , Reductase , Autophagy
	Isoliquiritigenin (ISL), an anti-tumor flavonoid from the root of Glycyrrhiza glabra, suppresses aldose reductase (IC50=320 nM).		Apoptosis , Influenza Virus , Reductase , Autophagy
TN1438	Beta-Amyrin acetate		Antioxidant , HMG-CoA Reductase , Epoxide Hydrolase , Antifungal
	beta-Amyrin acetate inhibits HMG-CoA Reductase (HMGCR) and sEH activity with IC50 of 3.4 μM. beta-Amyrin acetate has anti-inflammatory, antifungal, antioxidant, and anti-hyperlipidemic activities.
T0672	Pravastatin sodium	CS-514 Sodium,CS-514 (sodium)	Ferroptosis , HMG-CoA Reductase , Autophagy
	Pravastatin sodium (CS-514 (sodium)), an HMG-CoA reductase inhibitor, inhibits sterol synthesis with IC50 of 5.6 μM.		Ferroptosis , HMG-CoA Reductase , Autophagy
T0687	Simvastatin	MK-0733,MK 733	Apoptosis , Mitophagy , Ferroptosis , HMG-CoA Reductase , Autophagy
	Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity. Simvastatin has hypolipidemic activity, inhibits hepatic production of cholesterol, and is also used for the prevention of cardiovasc...
T1153	Trimethoprim	NIH 204,BW 56-72,NSC-106568	DHFR , DNA/RNA Synthesis , Antifolate , Antibacterial , Antibiotic
	Trimethoprim (NSC-106568) is a Dihydrofolate Reductase Inhibitor Antibacterial. The mechanism of action of trimethoprim is as a Dihydrofolate Reductase Inhibitor, and Cytochrome P450 2C8 Inhibitor, and Organic Cation Tra...
T3801	(Rac)-Byakangelicin	Bjacangelicin,Bjakangelicin,Biacangelicin,7H-Furo[3,2-g][1]benzopyran-7-one, 9-(2,3-dihydroxy-3-methylbutoxy)-4-methoxy-,Byakangelicin	Others
	(Rac)-Byakangelicin (7H-Furo[3,2-g][1]benzopyran-7-one, 9-(2,3-dihydroxy-3-methylbutoxy)-4-methoxy-) is an antineoplastic agent.		Others
TN1661	Ganoderic acid C2		Reductase , Histamine Receptor , Immunology/Inflammation related
	Ganoderic acid C2 has anti-inflammatory,and anti-tumor-promoting activities. Ganoderic acid C2 can inhibit histamine release, it also has inhibitory effects on the induction of Epstein-Barr Virus early antigen.
TN1016	Kukoamine A		NF-κB , Lipoxygenase , DNA/RNA Synthesis , Parasite
	Kukoamine A possesses anticancer, cytoprotective, antioxidant, and anti-inflammatory activities, it also has neuroprotective effects through inhibiting oxidative stress and apoptosis after whole-brain irradiation (WBI) i...		NF-κB , Lipoxygenase , DNA/RNA Synthesis , Parasite
T5372	L-SelenoMethionine	L-(+)-Selenomethionine	Apoptosis , Amino Acids and Derivatives , Endogenous Metabolite
	L-SelenoMethionine (L-(+)-Selenomethionine) is a naturally occurring amino acid. It promotes cell cycle progression and elevates the expression of the antioxidant enzymes thioredoxin reductase, glutathione reductase.
TN1975	Neosmitilbin	Neoastilbin	Others
	Neosmitilbin (Neoastilbin) may have antioxidant and anti-inflammatory activities, it shows potent inhibition of lens aldose reductase.		Others
TN1656	Ganoderenic acid A		Others
	Ganoderenic acid A has a potent hepatoprotective, and cytotoxic effects, it shows inhibitory activity on human aldose reductase in vitro.		Others
T3329	4',7-Dimethoxyisoflavone	Dimethoxydaidzein,Daidzein dimethyl ether	Endogenous Metabolite , Antifungal
	4',7-Dimethoxyisoflavone (Daidzein dimethyl ether) , a kind of isoflavonoids, showed inhibitory effects on rat prostate testosterone 5α-reductase.		Endogenous Metabolite , Antifungal
T5S0543	Isocurcumenol		Apoptosis , Estrogen Receptor/ERR , Reductase
	1. Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT).		Apoptosis , Estrogen Receptor/ERR , Reductase
TN5845	Neochlorogenic acid methyl ester	5-O-Caffeoylquinic acid methyl ester,Methyl 3-caffeoylquinate,GIP (1-39) acetate(725474-97-5 Free base),Methyl neochlorogenate	Antioxidant , HBV
	Neochlorogenic acid methyl ester (5-O-Caffeoylquinic acid methyl ester) is derived from Artemisia capillaris and black chokeberry (Aronia melanocarpa) fruits. Neochlorogenic acid methyl ester shows weak anti-HBV activity...		Antioxidant , HBV
T7730	Aminopterin	APGA,4-Aminofolic acid	Antifolate
	Aminopterin (4-Aminofolic acid) is a synthetic folic acid derivative whose metabolite is a competitive inhibitor of dihydrofolate reductase		Antifolate
T3S0507	Homovanillic acid	Homovaniuic acid,Vanilacetic acid,Vanillacetic acid	Others , Endogenous Metabolite
	Homovanillic acid (Vanillacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, growth hormone deficiency, celiac disease, and sepiapterin reductase deficiency.		Others , Endogenous Metabolite
T5S1026	Apigenin-7-glucuronide	Apigenin 7-O-glucuronide	MMP
	Apigenin-7-glucuronide (Apigenin 7-O-glucuronide) possesses multiple activities, including antioxidant, anti-inflammatory, and aldose reductase inhibitory activities, it can inhibit MMP activities (IC50s: 12.87, 22.39, 1...		MMP
TN2030	P-Hydroxyphenethyl trans-ferulate		5-HT Receptor
	P-Hydroxyphenethyl trans-ferulate exhibits affinity toward 5-HT(7) receptors in a competitive binding assay. P-Hydroxyphenethyl trans-ferulate can double quinone reductase specific activity in Hepa 1c1c7 cells at a level...		5-HT Receptor
T8072	S-Methyl-L-cysteine	S-Methylcysteine	Antioxidant , Reactive Oxygen Species
	S-Methyl-L-cysteine (S-Methylcysteine) is a natural product that acts as a substrate in the catalytic antioxidant system mediated by methionine sulfoxide reductase A (MSRA), with neuroprotective, antioxidative, and anti-...		Antioxidant , Reactive Oxygen Species
T6S0840	Engeletin	Dihydrokaempferol 3-rhamnoside	NF-κB , Reductase
	1. Engeletin (Dihydrokaempferol 3-rhamnoside) may serve as a potential anti-inflammatory agent. 2. Engeletin possesses potent inhibition of PGE2 release with IC5 values of 19.6 μg/ml. 3. Engeletin inhibits a recombinant ...		NF-κB , Reductase
TN2122	Quercetin 3-gentiobioside	Quercetin-3-gentiobioside	Reductase
	Quercetin 3-gentiobioside (Quercetin-3-gentiobioside) is an inhibitor of AR and AGE formation and can be extracted from A. iwayomogi.Quercetin 3-gentiobioside inhibits the biological activity of aldose reductase (AR) and...		Reductase
TN2272	Tigloylgomisin H		Nrf2
	Tigloylgomisin H represents a potential liver cancer prevention agent, it can significantly induce quinone reductase (QR) activity in Hepa1c1c7 mouse hepatocarcinoma cells, it functions as a novel monofunctional inducer ...		Nrf2
T3665	Tectoridin	Shekanin	Estrogen Receptor/ERR , Reductase
	Tectoridin (Shekanin) possesses an estrogenic and thyroid hormone-like agent by activating estrogen and thyroid hormone receptors. Tectoridin has anti-oxidant, anti-inflammatory and hypoglycemic activities; Tectoridin an...		Estrogen Receptor/ERR , Reductase
T4717	25-Hydroxycholesterol		Others , Endogenous Metabolite , HMG-CoA Reductase
	25-Hydroxycholesterol is a steroid derivative that suppresses the cleavage of sterol regulatory element binding proteins (SREBPs). It inhibits HMG-CoA reductase and so it also plays a significant role in the in vivo regu...		Others , Endogenous Metabolite , HMG-CoA Reductase
T14128	Adenosylcobalamin	Cobamamide,Coenzyme B12,AdoCbl	Endogenous Metabolite
	Adenosylcobalamin (AdoCbl) is a biologically active form of vitamin B12 .It is a cofactor for methylmalonyl CoA mutase. It belongs to the corrinoid group of compounds, which contain a corrin macrocycle, and is produced o...		Endogenous Metabolite
TN2111	Prunin	Naringenin 7-0-glucoside	Phosphatase , Anti-infection , Virus Protease
	Prunin (Naringenin 7-0-glucoside) possesses anti-diabetic, and anti-abacterial properties, it can inhibit protein tyrosine phosphatase 1B (PTP1B) and stimulate glucose uptake in insulin-resistant HepG2 cells; it also can...		Phosphatase , Anti-infection , Virus Protease
TN1037	Groenlandicine		Topoisomerase
	Groenlandicine is a protoberberine alkaloid from Coptidis Rhizoma. Groenlandicine exhibits moderate inhibitory effect with IC50 value of 154.2 μM for human recombinant aldose reductase (HRAR). Groenlandicine selectively ...		Topoisomerase
T5S1988	Isorhamnetin-3-O-glucoside	Isorhamnetin-3-O-beta-D-Glucoside	Others
	Isorhamnetin-3-O-glucoside (Isorhamnetin-3-O-beta-D-Glucoside) inhibits the activity of alpha-glucosidase from rat intestine; it exhibits a potent rat lens aldose reductase (RLAR) inhibition in vitro, its IC(50) being 1....		Others
T5813	BYAKANGELICIN		Reductase
	BYAKANGELICIN,a main furanocoumarin constituent isolated and characterized as an aldose reductase inhibitor,and is effective for the treatment of sugar cataracts and diabetic neuropathy and hence might be useful as a lea...		Reductase
T6102	2'-acetylacteoside		Antioxidant , Reductase
	2'-Acetylacteoside has antioxidative activity. It can significantly attenuate glutamate-induced neurotoxicity at concentrations ranging from 0.1 to 10 μM. 2'-Acetylacteoside shows antiproliferative effects on aortic smoo...		Antioxidant , Reductase
T2S1635	3-Isomangostin		MTH1
	3-Isomangostin is a potent human aldose reductase inhibitor with an IC50 of 3.48 uM; it is also an acetylcholinesterase selective inhibitor. 3-Isomangostin has free radical scavenging activity; it shows antiplasmodial ac...		MTH1
TL0008	Gigantol		Wnt/beta-catenin , Glucosidase
	Gigantol is a novel inhibitor of the Wnt/β-catenin pathway. It inhibits Wnt/β-catenin signaling through downregulation of phosphorylated LRP6 and cytosolic β-catenin in breast cancer cells. Gigantol may be developed as a...		Wnt/beta-catenin , Glucosidase
T4918	DL-Glyceraldehyde	Glyceric aldehyde	Reductase
	DL-Glyceraldehyde (Glyceric aldehyde) is produced from the action of the enzyme glyceraldehyde dehydrogenase, which converts glycerol to glyceraldehyde using NADP as a cofactor. When present at sufficiently high levels, ...		Reductase
T19365	Hydroxypyruvic acid	3-Hydroxypyruvic acid,β-Hydroxypyruvic acid	Others
	Hydroxypyruvic acid is an intermediate in the metabolism of glycine, serine, and threonine. It is a substrate for serine-pyruvate aminotransferase and glyoxylate reductase/hydroxypyruvate reductase.		Others
TN5183	Triptocalline A		Others
	Triptocalline A shows an inhibitory effect on rat lens aldose reductase.		Others
TN6514	2-Carboxybenzaldehyde
	The major peak of 2-Carboxybenzaldehyde reductase activity in human liver co-purifies with hAFAR protein. Sulphydryl substances and some proteins play important roles in preserving the molecular and catalytic properties ...
T81570	Paecilaminol	FKI-0550
	Paecilaminol (FKI-0550) is a potent inhibitor of the NADH-fumarate reductase enzyme, demonstrating an inhibitory concentration (IC50) of 5.1 µM against the NADH-fumarate reductase derived from Ascaris suum [1].
T40796	5β-Dihydrocortisone
	5β-Dihydrocortisone, a sterol metabolite derived from cortisone, is produced in the liver through the action of 5β-reductase (AKR1D1).
T19576	Tetrahydrocortisone		Others
	Tetrahydrocortisone, a stress-induced hormone and a urinary metabolite of Cortisone, originates from the reduction of Cortisone facilitated by 5-reductase.		Others
T75674	Pedunculagin
	Pedunculagin, a potent 5α-reductase type 1 inhibitor, effectively inhibits the production of nitric oxide (NO), IL-6, and IL-8 while also decreasing the protein expression of 5α-reductase. Additionally, it exhibits anti-...
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Natural Products

12-O-Methylcarnosic acid

Hesperetin 7-O-glucoside

TN1733

Synonym:

Target: Anti-infection, Antibacterial, HMG-CoA Reductase

Alpha-Estradiol

T3378

Synonym: Alfatradiol,17α-Estradiol,Epiestrol,Epiestradiol

Target: Estrogen/progestogen Receptor, Reductase, Endogenous Metabolite

Synonym: MK-803,Mevinolin

Target: Ferroptosis, HMG-CoA Reductase, Autophagy

Mevastatin

T0683

Synonym: Compactin,ML236B

Target: Apoptosis, Antibacterial, Antibiotic, HMG-CoA Reductase, Autophagy, Lipid

Meglutol

T1664

Synonym: Dicrotalic acid,3-Hydroxy-3-methylglutaric acid

Target: Endogenous Metabolite, HMG-CoA Reductase, Autophagy

Isoliquiritigenin

T0725

Synonym: ISL,Isoliquiritigen,GU17

Target: Apoptosis, Influenza Virus, Reductase, Autophagy

beta-Amyrin acetate

TN1438

Synonym:

Target: Antioxidant, HMG-CoA Reductase, Epoxide Hydrolase, Antifungal

Pravastatin sodium

T0672

Synonym: CS-514 Sodium,CS-514 (sodium)

Target: Ferroptosis, HMG-CoA Reductase, Autophagy

Simvastatin

T0687

Synonym: MK-0733,MK 733

Target: Apoptosis, Mitophagy, Ferroptosis, HMG-CoA Reductase, Autophagy

Trimethoprim

T1153

Synonym: NIH 204,BW 56-72,NSC-106568

Target: DHFR, DNA/RNA Synthesis, Antifolate, Antibacterial, Antibiotic

(Rac)-Byakangelicin

T3801

Synonym: Bjacangelicin,Bjakangelicin,Biacangelicin,7H-Furo[3,2-g][1]benzopyran-7-one, 9-(2,3-dihydroxy-3-methylbutoxy)-4-methoxy-,Byakangelicin

Target: Reductase, Histamine Receptor, Immunology/Inflammation related

Kukoamine A

TN1016

Synonym:

Target: NF-κB, Lipoxygenase, DNA/RNA Synthesis, Parasite

L-SelenoMethionine

T5372

Synonym: L-(+)-Selenomethionine

Target: Apoptosis, Amino Acids and Derivatives, Endogenous Metabolite

4',7-Dimethoxyisoflavone

T3329

Synonym: Dimethoxydaidzein,Daidzein dimethyl ether

Target: Endogenous Metabolite, Antifungal

Isocurcumenol

T5S0543

Synonym:

Target: Apoptosis, Estrogen Receptor/ERR, Reductase

Neochlorogenic acid methyl ester

TN5845

Synonym: 5-O-Caffeoylquinic acid methyl ester,Methyl 3-caffeoylquinate,GIP (1-39) acetate(725474-97-5 Free base),Methyl neochlorogenate

Target: Antioxidant, HBV

Aminopterin

T7730

Synonym: APGA,4-Aminofolic acid

Target: Antifolate

Homovanillic acid

T3S0507

Synonym: Homovaniuic acid,Vanilacetic acid,Vanillacetic acid

Target: Others, Endogenous Metabolite

Apigenin-7-glucuronide

T5S1026

Synonym: Apigenin 7-O-glucuronide

Target: MMP

P-Hydroxyphenethyl trans-ferulate

TN2030

Synonym:

Target: 5-HT Receptor

S-Methyl-L-cysteine

T8072

Synonym: S-Methylcysteine

Target: Antioxidant, Reactive Oxygen Species

Engeletin

T6S0840

Synonym: Dihydrokaempferol 3-rhamnoside

Target: NF-κB, Reductase

Quercetin 3-gentiobioside

TN2122

Synonym: Quercetin-3-gentiobioside

Target: Estrogen Receptor/ERR, Reductase

25-Hydroxycholesterol

T4717

Synonym:

Target: Others, Endogenous Metabolite, HMG-CoA Reductase

Adenosylcobalamin

T14128

Synonym: Cobamamide,Coenzyme B12,AdoCbl

Target: Endogenous Metabolite

Prunin

TN2111

Synonym: Naringenin 7-0-glucoside

Target: Phosphatase, Anti-infection, Virus Protease

Groenlandicine

TN1037

Synonym:

Target: Topoisomerase

Isorhamnetin-3-O-glucoside

T5S1988

Synonym: Isorhamnetin-3-O-beta-D-Glucoside

Target: Antioxidant, Reductase

Target: Wnt/beta-catenin, Glucosidase

DL-Glyceraldehyde

T4918

Synonym: Glyceric aldehyde

Target: Reductase

Hydroxypyruvic acid

T19365

Synonym: 3-Hydroxypyruvic acid,β-Hydroxypyruvic acid

2-Carboxybenzaldehyde

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Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPH-00288	Adrenodoxin reductase Protein, Bovine, Recombinant (His)	Bovine	Yeast
	Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitam...
TMPH-01224	Dihydrofolate reductase Protein, Human, Recombinant (His)	Human	E. coli
	Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds...
TMPH-00287	Adrenodoxin reductase Protein, Bovine, Recombinant (E. coli, His)	Bovine	E. coli
	Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitam...
TMPH-00608	Dihydrofolate reductase Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
TMPH-03535	Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc)	Staphylococcus aureus	E. coli
	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
TMPH-03581	Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His)	Staphylococcus epidermidis	E. coli
	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
TMPH-00218	DHCR7 Protein, Bovine, Recombinant (His)	Bovine	in vitro E. coli expression system
	7-dehydrocholesterol reductase of the cholesterol biosynthetic pathway reducing the C7-C8 double bond of cholesta-5,7-dien-3beta-ol (7-dehydrocholesterol/7-DHC) and cholesta-5,7,24-trien-3beta-ol, two intermediates in th...
TMPJ-00813	QDPR Protein, Human, Recombinant (His)	Human	Human Cells
	Dihydropteridine reductase, also known as HDHPR and Quinoid dihydropteridine reductase, QDPR and DHPR, belongs to the short-chain dehydrogenases/reductases (SDR) family. QDPR exists as a homodimer. QDPR is part of the pa...
TMPJ-01009	BLVRA Protein, Human, Recombinant (His)	Human	E. coli
	Human Biliverdin reductase A (BLVRA) is belonged to the Gfo/Idh/MocA family and Biliverdin reductase subfamily. BLVRA is an enzyme that in humans is encoded by the BLVRA gene. BLVRA plays an important role in reducing th...
TMPH-00625	FMN reductase Protein, E. coli, Recombinant (His)	E. coli	Baculovirus
	Catalyzes an NADPH-dependent reduction of FMN, but is also able to reduce FAD or riboflavin.
TMPJ-00937	RRM2 Protein, Human, Recombinant (His)	Human	Human Cells
	Ribonucleoside-Diphosphate Reductase Subunit M2 (RRM2) belongs to the ribonucleoside diphosphate reductase small chain family. The reductase of RRM2 catalyzes the formation of deoxyribonucleotides from ribonucleotides. S...
TMPH-03008	ENR Protein, Mycobacterium tuberculosis, Recombinant (His)	Mycobacterium tuberculosis	E. coli
	Enoyl-ACP reductase of the type II fatty acid syntase (FAS-II) system, which is involved in the biosynthesis of mycolic acids, a major component of mycobacterial cell walls. Catalyzes the NADH-dependent reduction of the ...
TMPY-01812	Enoyl-ACP Reductase Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Enoyl-ACP reductase, also known as NADH-dependent enoyl-ACP reductase and FABI, is a cell inner membrane and peripheral membrane protein which belongs to theshort-chain dehydrogenases/reductases (SDR) family and FabI ...
TMPY-03617	GMPR Protein, Human, Recombinant (His)	Human	E. coli
	GMPR, also known as GMPR1, belongs to the IMPDH/GMPR family.This familyofenzymesincludesIMP dehydrogenaseandGMP reductase. These enzymes are involved inpurine metabolism and adopt aTIM barrelstructure. GMPR is an enzyme ...
TMPY-00354	MSRB3 Protein, Human, Recombinant (hFc)	Human	HEK293
	MSRB3 (Methionine Sulfoxide Reductase B3) is a Protein Coding gene. The protein encoded by this gene catalyzes the reduction of methionine sulfoxide to methionine. This enzyme acts as a monomer and requires zinc as a cof...
TMPY-00538	MSRB3 Protein, Human, Recombinant (His)	Human	HEK293
	MSRB3 (Methionine Sulfoxide Reductase B3) is a Protein Coding gene. The protein encoded by this gene catalyzes the reduction of methionine sulfoxide to methionine. This enzyme acts as a monomer and requires zinc as a cof...
TMPY-02438	AKR1B1 Protein, Human, Recombinant (His)	Human	E. coli
	Aldose reductase (AKR1B1) belongs to the aldo/keto reductase superfamily. AKR1B1 is a NADPH-dependent aldo-keto reductase best known as the rate-limiting enzyme of the polyol pathway. Expression of AKR1B1 was the highest...
TMPH-00658	NAD(P)H-flavin reductase Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Catalyzes the reduction of soluble flavins by reduced pyridine nucleotides.
TMPY-02461	AKR1A1 Protein, Human, Recombinant (His)	Human	E. coli
	Aldehyde reductase (AKR1A1) is a member of the aldo-keto reductase superfamily, which consists of more than 40 known enzymes and proteins that includes variety of monomeric NADPH-dependent oxidoreductases, such as aldehy...
TMPY-03287	RRM1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	RRM1 is a subunit of ribonucleoside-diphosphate reductase which is constituted by two subunits. Ribonucleoside-diphosphate reductase is an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesi...
TMPY-03867	CBR3 Protein, Human, Recombinant (His)	Human	E. coli
	CBR3, also known as hCBR3, belongs to the short-chain dehydrogenases/reductases (SDR) family. CBR3 is expressed in ovary, pancreas, intestine, colon, kidney, brain, thymus, lung, heart, liver, spleen, leukocyte, prostate...
TMPH-00683	TMAO reductase 1 Protein, E. coli O157:H7, Recombinant (His & Myc)	E. coli	E. coli
	Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions.
TMPH-02498	AKR1C3 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Catalyzes the dehydrogenation of 17-beta-hydroxysteroids. May also exhibit significant activity with a variety of cyclic and alicyclic alcohols. Uses both NAD and NADP, but the activity is much greater with NAD than with...
TMPY-02527	P53R2 Protein, Human, Recombinant (His)	Human	E. coli
	Ribonucleoside reductase subunit M2B, also known as RRM2B or p53R2, is an enzyme belonging to the iron-dependent ribonucleotide reductase (RNR) enzyme family which is essential for DNA synthesis. Ribonucleotide reductase...
TMPY-02519	BLVRB Protein, Human, Recombinant (His)	Human	E. coli
	Biliverdin reductase (hBVR) is a serine/threonine kinase that catalyzes reduction of the heme oxygenase (HO) activity product, biliverdin, to bilirubin. BVR consists of an N-terminal dinucleotide-binding domain (Rossmann...
TMPH-01748	CYPOR Protein, Human, Recombinant (GST)	Human	E. coli
	This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5.
TMPH-02801	CYPOR Protein, Mouse, Recombinant (His)	Mouse	E. coli
	CYPOR Protein, Mouse, Recombinant (His) is expressed in E. coli.
TMPH-00097	AtAER Protein, Arabidopsis thaliana, Recombinant (His & SUMO)	Arabidopsis thaliana	E. coli
	Involved in the detoxification of reactive carbonyls. Acts on lipid peroxide-derived reactive aldehydes. Specific to a double bond activated by an adjacent carbonyl group. Can use both quinones and diamide as substrates,...
TMPH-00098	AtAER Protein, Arabidopsis thaliana, Recombinant	Arabidopsis thaliana	E. coli
	Involved in the detoxification of reactive carbonyls. Acts on lipid peroxide-derived reactive aldehydes. Specific to a double bond activated by an adjacent carbonyl group. Can use both quinones and diamide as substrates,...
TMPJ-00955	MDH1 Protein, Human, Recombinant (His)	Human	E. coli
	Malate Dehydrogenase, Cytoplasmic (MDH1) is an enzyme which belongs to the MDH Type 2 sub-family of LDH/MDH superfamily. MDH1 is involved in the Citric Acid Cycle that catalyzes the conversion of Malate into Oxaloacetate...
TMPY-02271	TRXR1/TXNRD1 Protein, Human, Recombinant (aa 161-647, His)	Human	E. coli
	Thioredoxin reductase 1 (TXNRD1) which is a selenocysteine-containing protein is overexpressed in many malignancies. TXNRD1 plays a key role in regulating cell growth and transformation, and protects cells against oxidat...
TMPY-03460	DCXR Protein, Human, Recombinant (His)	Human	E. coli
	DCXR, also known as HCR2, belongs to the short-chain dehydrogenases/reductases (SDR) family. It is highly expressed in kidney, liver and epididymis. In the epididymis, DCXR is mainly expressed in the proximal and dist...
TMPY-02652	CYB5R1 Protein, Human, Recombinant (His)	Human	E. coli

TMPH-01039	CBR1 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction...
TMPH-01040	CBR1 Protein, Human, Recombinant (His)	Human	Yeast
	NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction...
TMPJ-00460	MECR Protein, Human, Recombinant (His)	Human	Human Cells
	Trans-2-Enoyl-CoA Reductase Mitochondrial (MECR) belongs to the zinc-containing alcohol dehydrogenase family. MECR localizes to the mitochondrion. It is highly expressed in skeletal and heart muscle and expressed at lowe...
TMPJ-01111	TSTA3 Protein, Human, Recombinant (His)	Human	E. coli
	GDP-L-Fucose Synthase is a NADP(H)-binding protein. It catalyzes the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-dexoymannose to GDP-L-fucose. GDP-L-Fucose is the...
TMPJ-00207	AKR1C2 Protein, Human, Recombinant	Human	E. coli
	Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) plays a role in concert with the 5-α/5-β-Steroid Reductases to convert Steroid hormones into the 3-α/5-α and 3-α/5-β-Tetrahydrosteroids. AKR1C2 catalyzes the inactivation o...
TMPJ-01098	PRDX4 Protein, Human, Recombinant (His)	Human	E. coli
	Peroxiredoxin-4 (PRDX4) is a member of the AhpC/TSA family. PRDX4 is a cytoplasmic protein and contains one thioredoxin domain. PRDX4 exists in homodimer or heterodimer with PRDX1. PRDX4 reduces hydrogen peroxide and alk...
TMPY-00481	AKR1C4 Protein, Human, Recombinant (His)	Human	E. coli
	Aldo-keto reductases comprise of AKR1C1-AKR1C4, four enzymes that catalyze NADPH dependent reductions and have been implicated in biosynthesis, intermediary metabolism, and detoxification. there is a strong correlation ...
TMPJ-00463	BDH2 Protein, Human, Recombinant (His)	Human	E. coli
	3-Hydroxybutyrate Dehydrogenase Type 2 belongs to the short-chain dehydrogenases/reductases (SDR) family. 3-Hydroxybutyrate Dehydrogenase Type 2 may play an important role in the peripheral utilization of 3-hydroxybutyra...
TMPH-00160	Cytochrome P450 BM-3 Protein, Bacillus megaterium, Recombinant (His & Myc)	Bacillus megaterium	E. coli
	Cytochrome P450 BM-3 Protein, Bacillus megaterium, Recombinant (His & Myc) is expressed in E. coli.
TMPY-03497	AKR1C2 Protein, Human, Recombinant (His)	Human	E. coli
	AKR1C2 is a member of the aldo/keto reductase superfamily, which consists of more than 4 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using ...
TMPY-03859	DHRS9 Protein, Human, Recombinant (His)	Human	E. coli
	Dehydrogenase/reductase (SDR family) member 9 (DHRS9) is aberrantly expressed in colorectal cancer (CRC), the decreased expression of DHRS9 correlates with tumor progression and may serve as a potential prognostic bioma...
TMPJ-00962	AKR1C3 Protein, Human, Recombinant (His)	Human	Human Cells
	AKR1C3, is an enzyme which belongs to the aldo/keto reductase family. It is expressed in many tissues including adrenal gland, brain, kidney, liver, lung, mammary gland, placenta, small intestine, colon, spleen, prostate...
TMPJ-00934	PRDX3 Protein, Human, Recombinant	Human	E. coli
	Thioredoxin-Dependent Peroxide Reductase Mitochondrial (PRDX3) is an enzyme that belongs to the AhpC/TSA family. Human and mouse PRDX3 genes are highly conserved, and they map to the regions syntenic between mouse and hu...
TMPJ-00933	PRDX5 Protein, Human, Recombinant (His)	Human	Human Cells
	Peroxisomes are essential organelles that participate in multiple important metabolic processes, including the β-oxidation of fatty acids, plasmalogen synthesis, and the metabolism of reactive oxygen species (ROS). Perox...
TMPJ-00801	UQCRH Protein, Human, Recombinant (GST)	Human	E. coli
	Cytochrome b-c1 complex subunit 6, mitochondrial (UQCRH) belongs to the UQCRH/QCR6 family, it is a subunit of the respiratory chain protein Ubiquinol Cytochrome c Reductase. This is a component of the ubiquinol-cytochrom...
TMPY-03407	NQO1 Protein, Human, Recombinant (His)	Human	E. coli
	NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-...
TMPY-00989	LDLR Protein, Human, Recombinant (His)	Human	HEK293
	LDL Receptor, also known as LDLR, is a mosaic protein that belongs to the Low-density lipoprotein receptor gene family. The low-density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved i...
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Adrenodoxin reductase Protein, Bovine, Recombinant (His)

TMPH-00288

Species: Bovine

Expression System: Yeast

Dihydrofolate reductase Protein, Human, Recombinant (His)

TMPH-01224

Species: Human

Expression System: E. coli

Adrenodoxin reductase Protein, Bovine, Recombinant (E. coli, His)

TMPH-00287

Species: Bovine

Expression System: E. coli

Dihydrofolate reductase Protein, E. coli, Recombinant (His)

TMPH-00608

Species: E. coli

Expression System: E. coli

Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc)

TMPH-03535

Species: Staphylococcus aureus

Expression System: E. coli

Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His)

TMPH-03581

Species: Staphylococcus epidermidis

Expression System: E. coli

DHCR7 Protein, Bovine, Recombinant (His)

TMPH-00218

Species: Bovine

Expression System: in vitro E. coli expression system

QDPR Protein, Human, Recombinant (His)

TMPJ-00813

Species: Human

Expression System: Human Cells

BLVRA Protein, Human, Recombinant (His)

TMPJ-01009

Species: Human

Expression System: E. coli

FMN reductase Protein, E. coli, Recombinant (His)

TMPH-00625

Species: E. coli

Expression System: Baculovirus

RRM2 Protein, Human, Recombinant (His)

TMPJ-00937

Species: Human

Expression System: Human Cells

ENR Protein, Mycobacterium tuberculosis, Recombinant (His)

TMPH-03008

Species: Mycobacterium tuberculosis

Expression System: E. coli

Enoyl-ACP Reductase Protein, E. coli, Recombinant (His)

TMPY-01812

Species: E. coli

Expression System: E. coli

GMPR Protein, Human, Recombinant (His)

TMPY-03617

Species: Human

Expression System: E. coli

MSRB3 Protein, Human, Recombinant (hFc)

TMPY-00354

Species: Human

Expression System: HEK293

MSRB3 Protein, Human, Recombinant (His)

TMPY-00538

Species: Human

Expression System: HEK293

AKR1B1 Protein, Human, Recombinant (His)

TMPY-02438

Species: Human

Expression System: E. coli

NAD(P)H-flavin reductase Protein, E. coli, Recombinant (His)

TMPH-00658

Species: E. coli

Expression System: E. coli

AKR1A1 Protein, Human, Recombinant (His)

TMPY-02461

Species: Human

Expression System: E. coli

RRM1 Protein, Human, Recombinant (His & GST)

TMPY-03287

Species: Human

Expression System: Baculovirus-Insect Cells

CBR3 Protein, Human, Recombinant (His)

TMPY-03867

Species: Human

Expression System: E. coli

TMAO reductase 1 Protein, E. coli O157:H7, Recombinant (His & Myc)

TMPH-00683

Species: E. coli

Expression System: E. coli

AKR1C3 Protein, Mouse, Recombinant (His & Myc)

TMPH-02498

Species: Mouse

Expression System: E. coli

p53R2 Protein, Human, Recombinant (His)

TMPY-02527

Species: Human

Expression System: E. coli

BLVRB Protein, Human, Recombinant (His)

TMPY-02519

Species: Human

Expression System: E. coli

CYPOR Protein, Human, Recombinant (GST)

TMPH-01748

Species: Human

Expression System: E. coli

CYPOR Protein, Mouse, Recombinant (His)

TMPH-02801

Species: Mouse

Expression System: E. coli

AtAER Protein, Arabidopsis thaliana, Recombinant (His & SUMO)

TMPH-00097

Species: Arabidopsis thaliana

Expression System: E. coli

AtAER Protein, Arabidopsis thaliana, Recombinant

TMPH-00098

Species: Arabidopsis thaliana

Expression System: E. coli

MDH1 Protein, Human, Recombinant (His)

TMPJ-00955

Species: Human

Expression System: E. coli

TRXR1/TXNRD1 Protein, Human, Recombinant (aa 161-647, His)

TMPY-02271

Species: Human

Expression System: E. coli

DCXR Protein, Human, Recombinant (His)

TMPY-03460

Species: Human

Expression System: E. coli

CYB5R1 Protein, Human, Recombinant (His)

TMPY-02652

Species: Human

Expression System: E. coli

CBR1 Protein, Human, Recombinant (E. coli, His)

TMPH-01039

Species: Human

Expression System: E. coli

CBR1 Protein, Human, Recombinant (His)

TMPH-01040

Species: Human

Expression System: Yeast

MECR Protein, Human, Recombinant (His)

TMPJ-00460

Species: Human

Expression System: Human Cells

TSTA3 Protein, Human, Recombinant (His)

TMPJ-01111

Species: Human

Expression System: E. coli

AKR1C2 Protein, Human, Recombinant

TMPJ-00207

Species: Human

Expression System: E. coli

PRDX4 Protein, Human, Recombinant (His)

TMPJ-01098

Species: Human

Expression System: E. coli

AKR1C4 Protein, Human, Recombinant (His)

TMPY-00481

Species: Human

Expression System: E. coli

BDH2 Protein, Human, Recombinant (His)

TMPJ-00463

Species: Human

Expression System: E. coli

Cytochrome P450 BM-3 Protein, Bacillus megaterium, Recombinant (His & Myc)

TMPH-00160

Species: Bacillus megaterium

Expression System: E. coli

AKR1C2 Protein, Human, Recombinant (His)

TMPY-03497

Species: Human

Expression System: E. coli

DHRS9 Protein, Human, Recombinant (His)

TMPY-03859

Species: Human

Expression System: E. coli

AKR1C3 Protein, Human, Recombinant (His)

TMPJ-00962

Species: Human

Expression System: Human Cells

PRDX3 Protein, Human, Recombinant

TMPJ-00934

Species: Human

Expression System: E. coli

PRDX5 Protein, Human, Recombinant (His)

TMPJ-00933

Species: Human

Expression System: Human Cells

UQCRH Protein, Human, Recombinant (GST)

TMPJ-00801

Species: Human

Expression System: E. coli

NQO1 Protein, Human, Recombinant (His)

TMPY-03407

Species: Human

Expression System: E. coli

LDLR Protein, Human, Recombinant (His)

TMPY-00989

Species: Human

Expression System: HEK293

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Cat No.	Product Name
L2510	Lipid Metabolism Compound Library		496 compounds
	A unique collection of 496 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).

Libraries

Lipid Metabolism Compound Library

L2510

Compounds: 496