T12463 |
PI3kδ inhibitor 1
|
1332075-63-4
|
98%
|
|
PI3kδ inhibitor 1 is a selective inhibitor of PI3Kδ (IC50 of 3.8 nM).
|
T13140 |
Umbralisib R-enantiomer
|
1532533-69-9
|
98%
|
|
Umbralisib R-enantiomer (TGR-1202 R-enantiomer) is an inhibitor of PI3Kδ, which is the less active enantiomer of TGR-1202.
|
TN1034 |
Sennidin B
|
517-44-2
|
98%
|
|
Sennidin B stimulates glucose incorporation in rat adipocytes.
|
T10660L |
CAL-130 Hydrochloride
|
1431697-78-7
|
98%
|
|
CAL-130 Hydrochloride is a PI3Kδ and PI3Kγ inhibitor (IC50s: 1.3 and 6.1 nM).
|
TN1033 |
Sennidin A
|
641-12-3
|
98%
|
|
Sennidin A, has two hydroxyanthraquinone-like moieties, exerts inhibition on NS3 helicase with IC50 values of 0.8 μM.
|
T13973 |
(Z)-GW 5074
|
1233748-60-1
|
98%
|
|
(Z)-GW 5074 interacts with both mHTT (mutant huntingtin protein) and LC3.
|
TN1504 |
Citreorosein
|
481-73-2
|
98%
|
|
Citreorosein is a cAMP phosphodiesterase inhibitor, it has anti-inflammatory effect, inhibits proinflammatory cytokines production through the inhibition of both...
|
TN4213 |
Hirsutenone
|
41137-87-5
|
98%
|
|
Hirsutenone has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition effect on the mitochondrial lipid pero...
|
T12461 |
PI3Kdelta inhibitor 1
|
2242109-74-4
|
98%
|
|
PI3Kdelta inhibitor 1 is a potent, selective and orally available inhibitor of PI3Kδ with an IC50 of 1.3 nM.
|
T17066 |
Umbralisib hydrochloride
|
1532533-78-0
|
98%
|
|
Umbralisib hydrochloride is a novel PI3Kδ inhibitor (IC50 and EC50 of 22.2 nM and 24.3 nM, respectively). Umbralisib hydrochloride is also active against CK1ε (E...
|
T10660 |
CAL-130
|
1431697-74-3
|
98%
|
|
CAL-130 is a PI3Kδ and PI3Kγ inhibitor (IC50s: 1.3 and 6.1 nM).
|
T12456 |
PI3K-IN-10
|
2211922-64-2
|
98%
|
|
PI3K-IN-10 is a potent inhibitor of pan-PI3K .
|
TN2328 |
Zeylenone
|
193410-84-3
|
98%
|
|
Zeylenone has good antitumor efficacy, it inhibits proliferation and induces apoptosis in cervical carcinoma cells via PI3K/AKT/mTOR and MAPK/ERK pathways. Zeyle...
|
TN1367 |
Alismol
|
87827-55-2
|
98%
|
|
Alismol has antihypertensive action, it decreases cardiac output, heart rate and left ventricular pressure, but it increases coronary flow, it has been used for ...
|
T2S0606 |
Bakkenolide A
|
19906-72-0
|
98%
|
|
Bakkenolide A has antifeedant and growth inhibitory effects on neonate variegated cutworms, it inhibits leukemia by regulation of HDAC3 and PI3K/Akt-related sign...
|
TN5050 |
Sprengerinin C
|
88861-91-0
|
98%
|
|
Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and angiogenesis and induction of apoptosis, it can st...
|
T6850 |
GSK2292767
|
1254036-66-2
|
98%
|
|
GSK2292767 is a potent and selective PI3Kδ inhibitor.
|
TN3218 |
7-(4-Hydroxyphenyl)-1-phenyl-4-hepten-3-one
|
100667-52-5
|
98%
|
|
7-(4-Hydroxyphenyl)-1-phenyl-4-hepten-3-one as a beneficial compound to ameliorate the deleterious effects of Aβ on dendrite integrity and cell survival, and may...
|
T6730 |
WAY-600
|
1062159-35-6
|
98%
|
|
WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM; blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) but not P-AKT(T308); sel...
|
TMA0291 |
Dehydroglyasperin D
|
517885-72-2
|
98%
|
|
Dehydroglyasperin D exhibits anticancer, anti-inflammatory, anti-obesity, antioxidant and anti-aldose reductase effects, it inhibits the proliferation of HT-29 h...
|