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Sodium Channel

Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's plasma membrane.
Cat No. product name
T16514 PF 04531083 PF 04531083 是 NaV1.8 通道的特异性阻断剂。 PF 04531083 可用于神经性和炎症性疼痛的相关研究。
T22675 Co 102862 Co 102862 是一种电压门控钠通道阻滞剂。 Co 102862 可用于抗惊厥的研究。
T7182 Metaflumizone Metaflumizone is a sodium channel blocker insecticide.
T1033 Monensin sodium salt Monensin sodium is an antiprotozoal agent produced by Streptomyces cinnamonensis.Monensin sodium salt causes a marked enlargement of the MVBs and regulates exoso...
T0802 Procaine hydrochloride Procaine Hydrochloride is the hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds ...
T0249 N-Acetylprocainamide N-Acetylprocainamide, the N-acetylated metabolite of Procainamide, is a Class III antiarrhythmic agent, while procainamide is a Class Ia antiarrhythmic drug.
T0678 Amitriptyline hydrochloride Amitriptyline Hydrochloride is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and antinociceptive activities.
T3524 Halofuginone hydrobromide Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of...
T5850 Benzamil Benzamil is an epithelial sodium channel (ENaC) blocker that inhibits sodium transport from (IC50 = 4 nM) and binds to (Kd = 5 nM) bovine kidney cortex membrane ...
TP1852 Myomodulin Myomodulin is a neuropeptide present in molluscs, insects, and gastropods.Myomodulin is present in two identified aplysia neurons that contain myomodulin A the A...
T6856 Halofuginone Halofuginone, the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in the mamm...
T6645 Ropivacaine hydrochloride monohydrate Ropivacaine HCl is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly.
T0167 Vinpocetine Vinpocetine is a selective inhibitor of cyclic GMP phosphodiesterase (PDE).
T1198 Tetracaine hydrochloride Tetracaine hydrochloride (Pontocaine), a potent local anaesthetic, is a channel function allosteric inhibitor. It is primarily used as an antipruritic and topica...
T23213 QX-222 chloride Sodium channel blocker
T0939 Phenytoin Phenytoin is a hydantoin derivative and a non-sedative antiepileptic agent with anticonvulsant activity. Phenytoin potentially acts by promoting sodium efflux fr...
T0175L Amiloride hydrochloride dihydrate Amiloride hydrochloride is a pyrazine compound inhibiting SODIUM reabsorption through SODIUM CHANNELS in renal EPITHELIAL CELLS. This inhibition creates a negati...
T1332 Permethrin Permethrin is a pyrethroid insecticide commonly used in the treatment of LICE INFESTATIONS and SCABIES.
T21769L β-Pompilidotoxin Acetate β-Pompilidotoxin Acetate is a wasp venom peptide. β-Pompilidotoxin Acetate can slow sodium channel inactivation and increase steady-state sodium current in cells...
T1073 Dronedarone hydrochloride Dronedarone hydrochloride is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.
TN1740 Homoeriodictyol Homoeriodictyol, a naturally occurring, bitter-masking flavanone, as a promising agent to increase appetite and food intake. The flavanone homoeriodictyol can in...
T0796 Prilocaine hydrochloride Prilocaine hydrochloride is a local anesthetic of the amino amide type, binds to voltage-gated sodium ion channels in the neuronal membrane, thereby preventing t...
T3956 Sodium ionophore III Sodium ionophore III (ETH2120) is a Na+ ionophore suitable for the test of sodium activity in plasma, serum, and blood.
T4008 Metergoline Metergoline is a dopamine agonist and serotonin antagonist. It has been used similarly to BROMOCRIPTINE as a dopamine agonist and also for migraine disorder ther...
T7064 Valproic Acid Valproic Acid is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels. Currently, the various mol...
T1053 Mebeverine hydrochloride Mebeverine hydrochloride, a β-phenylethylamine derivative, is a potent α1 repector inhibitor, relaxing the muscles in and around the gut.
T0916 Butamben Butamben is a long-duration local anesthetic used for the treatment of chronic pain.
T0222 Proparacaine hydrochloride Proparacaine Hydrochloride is the hydrochloride salt form of proparacaine, a benzoic acid derivative with local anesthetic property. Proparacaine hydrochloride s...
T0037 Halazone Halazone is fine white powder with an odor of chlorine. It has been widely used to disinfect drinking water.
T0943 Carbamazepine Carbamazepine is a tricyclic compound chemically related to tricyclic antidepressants (TCA) with anticonvulsant and analgesic properties. Carbamazepine exerts it...
T37688 Cyfluthrin Cyfluthrin is a pyrethroid insecticide and a modulator of voltage-gated sodium channels (Nav).1,2It slowly activates rat recombinant Nav1.8 channels, delays inac...
T0440 Oxcarbazepine Oxcarbazepine is an Anti-epileptic Agent. The physiologic effect of oxcarbazepine is by means of Decreased Central Nervous System Disorganized Electrical Activit...
T2806 Lappaconitine Lappaconitine, isolated from Aconitum sinomontanum Nakai, was characterized as an analgesic.
T0207 Ranolazine dihydrochloride Ranolazine(RS-43285), an antianginal agent, can treat arrhythmia via a novel mechanism of action (inhibition of the late phase of the inward sodium current), and...
T4699 5-(N,N-Hexamethylene)-amiloride HMA is an amiloride derivative, shown to inhibit TRPA1-mediated calcium signal (IC50: 35 µM). It is an inhibitor of the Na+/H+ exchanger (NHE), with Ki of 0.013-...
T3402 20(S)-Ginsenoside Rg3 Ginsenoside Rg3 possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells. It inhibits the prol...
T6633 Ranolazine Ranolazine is a calcium uptake inhibitor via the sodium/calcium channel, used to treat chronic angina. It affects the sodium-dependent calcium channels during my...
T0018 Procainamide hydrochloride Procainamide Hydrochloride is the hydrochloride salt form of procainamide, an amide derivative exhibiting class 1A antiarrhythmic property and analog of procaine...
T1384 Chlorpromazine hydrochloride Chlorpromazine hydrochloride is the prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are ...
T7056 Dronedarone Dronedarone is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.
T6234 Ambroxol hydrochloride Ambroxol hydrochloride is a metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually admin...
T2391 Camostat mesylate Camostat is a trypsin-like protease inhibitor and inhibits airway epithelial sodium channel (ENaC) function.
T9685 DS-1971a DS-1971a is a highly potent and selective NaV1.7 inhibitor. DS-1971a exhibits a favorable toxicological profile and analgesic effects.
T12421 PF-04885614 PF-04885614 is a potent inhibitor of NaV1.8, has potential for neurological and neurodevelopmental diseases treatment.
T1144 Lidocaine hydrochloride Lidocaine hydrochloride is a local anesthetic and cardiac depressant used as an antiarrhythmic agent. Its actions are more intense and its effects more prolonged...
T1409 Methocarbamol Methocarbamol is a centrally acting muscle relaxant whose mode of action has not been established. It is used as an adjunct in the symptomatic treatment of muscu...
T27794 λ-Cyhalothrin lambda-Cyhalothrin is an insecticide and pesticide.
T0806 Flunarizine dihydrochloride Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. Flunarizine hydrochloride is effective in...
TN2239 Strictosamide Strictosamide possesses antibacterial and antiviral activities, it also may have important effects on inflammation and inflammatory pain.
T0470 Nefopam hydrochloride Nefopam Hydrochloride is the hydrochloride salt form of nefopam, a centrally-acting, non-opioid benzoxazocine with analgesic activity.
PF 04531083
T16514
PF 04531083 是 NaV1.8 通道的特异性阻断剂。 PF 04531083 可用于神经性和炎症性疼痛的相关研究。
Co 102862
T22675
Co 102862 是一种电压门控钠通道阻滞剂。 Co 102862 可用于抗惊厥的研究。
Metaflumizone
T7182
Metaflumizone is a sodium channel blocker insecticide.
Monensin sodium salt
T1033
Monensin sodium is an antiprotozoal agent produced by Streptomyces cinnamonensis.Monensin sodium salt causes a marked enlargement of the MVBs and regulates exoso...
Procaine hydrochloride
T0802
Procaine Hydrochloride is the hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds ...
N-Acetylprocainamide
T0249
N-Acetylprocainamide, the N-acetylated metabolite of Procainamide, is a Class III antiarrhythmic agent, while procainamide is a Class Ia antiarrhythmic drug.
Amitriptyline hydrochloride
T0678
Amitriptyline Hydrochloride is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and antinociceptive activities.
Halofuginone hydrobromide
T3524
Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of...
Benzamil
T5850
Benzamil is an epithelial sodium channel (ENaC) blocker that inhibits sodium transport from (IC50 = 4 nM) and binds to (Kd = 5 nM) bovine kidney cortex membrane ...
Myomodulin
TP1852
Myomodulin is a neuropeptide present in molluscs, insects, and gastropods.Myomodulin is present in two identified aplysia neurons that contain myomodulin A the A...
Halofuginone
T6856
Halofuginone, the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in the...
Ropivacaine hydrochloride monohydrate
T6645
Ropivacaine HCl is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly.
Vinpocetine
T0167
Vinpocetine is a selective inhibitor of cyclic GMP phosphodiesterase (PDE).
Tetracaine hydrochloride
T1198
Tetracaine hydrochloride (Pontocaine), a potent local anaesthetic, is a channel function allosteric inhibitor. It is primarily used as an antipruritic and topica...
QX-222 chloride
T23213
Sodium channel blocker
Phenytoin
T0939
Phenytoin is a hydantoin derivative and a non-sedative antiepileptic agent with anticonvulsant activity. Phenytoin potentially acts by promoting sodium efflux fr...
Amiloride hydrochloride dihydrate
T0175L
Amiloride hydrochloride is a pyrazine compound inhibiting SODIUM reabsorption through SODIUM CHANNELS in renal EPITHELIAL CELLS. This inhibition creates a negati...
Permethrin
T1332
Permethrin is a pyrethroid insecticide commonly used in the treatment of LICE INFESTATIONS and SCABIES.
β-Pompilidotoxin Acetate
T21769L
β-Pompilidotoxin Acetate is a wasp venom peptide. β-Pompilidotoxin Acetate can slow sodium channel inactivation and increase steady-state sodium current in cel...
Dronedarone hydrochloride
T1073
Dronedarone hydrochloride is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.
Homoeriodictyol
TN1740
Homoeriodictyol, a naturally occurring, bitter-masking flavanone, as a promising agent to increase appetite and food intake. The flavanone homoeriodictyol can in...
Prilocaine hydrochloride
T0796
Prilocaine hydrochloride is a local anesthetic of the amino amide type, binds to voltage-gated sodium ion channels in the neuronal membrane, thereby preventing t...
Sodium ionophore III
T3956
Sodium ionophore III (ETH2120) is a Na+ ionophore suitable for the test of sodium activity in plasma, serum, and blood.
Metergoline
T4008
Metergoline is a dopamine agonist and serotonin antagonist. It has been used similarly to BROMOCRIPTINE as a dopamine agonist and also for migraine disorder ther...
Valproic Acid
T7064
Valproic Acid is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels. Currently, the various mol...
Mebeverine hydrochloride
T1053
Mebeverine hydrochloride, a β-phenylethylamine derivative, is a potent α1 repector inhibitor, relaxing the muscles in and around the gut.
Butamben
T0916
Butamben is a long-duration local anesthetic used for the treatment of chronic pain.
Proparacaine hydrochloride
T0222
Proparacaine Hydrochloride is the hydrochloride salt form of proparacaine, a benzoic acid derivative with local anesthetic property. Proparacaine hydrochloride s...
Halazone
T0037
Halazone is fine white powder with an odor of chlorine. It has been widely used to disinfect drinking water.
Carbamazepine
T0943
Carbamazepine is a tricyclic compound chemically related to tricyclic antidepressants (TCA) with anticonvulsant and analgesic properties. Carbamazepine exerts it...
Cyfluthrin
T37688
Cyfluthrin is a pyrethroid insecticide and a modulator of voltage-gated sodium channels (Nav).1,2It slowly activates rat recombinant Nav1.8 channels, delays inac...
Oxcarbazepine
T0440
Oxcarbazepine is an Anti-epileptic Agent. The physiologic effect of oxcarbazepine is by means of Decreased Central Nervous System Disorganized Electrical Activit...
Lappaconitine
T2806
Lappaconitine, isolated from Aconitum sinomontanum Nakai, was characterized as an analgesic.
Ranolazine dihydrochloride
T0207
Ranolazine(RS-43285), an antianginal agent, can treat arrhythmia via a novel mechanism of action (inhibition of the late phase of the inward sodium current), and...
5-(N,N-Hexamethylene)-amiloride
T4699
HMA is an amiloride derivative, shown to inhibit TRPA1-mediated calcium signal (IC50: 35 µM). It is an inhibitor of the Na+/H+ exchanger (NHE), with Ki of 0.013...
20(S)-Ginsenoside Rg3
T3402
Ginsenoside Rg3 possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells. It inhibits the prol...
Ranolazine
T6633
Ranolazine is a calcium uptake inhibitor via the sodium/calcium channel, used to treat chronic angina. It affects the sodium-dependent calcium channels during my...
Procainamide hydrochloride
T0018
Procainamide Hydrochloride is the hydrochloride salt form of procainamide, an amide derivative exhibiting class 1A antiarrhythmic property and analog of procaine...
Chlorpromazine hydrochloride
T1384
Chlorpromazine hydrochloride is the prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are ...
Dronedarone
T7056
Dronedarone is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.
Ambroxol hydrochloride
T6234
Ambroxol hydrochloride is a metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually admin...
Camostat mesylate
T2391
Camostat is a trypsin-like protease inhibitor and inhibits airway epithelial sodium channel (ENaC) function.
DS-1971a
T9685
DS-1971a is a highly potent and selective NaV1.7 inhibitor. DS-1971a exhibits a favorable toxicological profile and analgesic effects.
PF-04885614
T12421
PF-04885614 is a potent inhibitor of NaV1.8, has potential for neurological and neurodevelopmental diseases treatment.
Lidocaine hydrochloride
T1144
Lidocaine hydrochloride is a local anesthetic and cardiac depressant used as an antiarrhythmic agent. Its actions are more intense and its effects more prolonged...
Methocarbamol
T1409
Methocarbamol is a centrally acting muscle relaxant whose mode of action has not been established. It is used as an adjunct in the symptomatic treatment of muscu...
λ-Cyhalothrin
T27794
lambda-Cyhalothrin is an insecticide and pesticide.
Flunarizine dihydrochloride
T0806
Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. Flunarizine hydrochloride is effective in...
Strictosamide
TN2239
Strictosamide possesses antibacterial and antiviral activities, it also may have important effects on inflammation and inflammatory pain.
Nefopam hydrochloride
T0470
Nefopam Hydrochloride is the hydrochloride salt form of nefopam, a centrally-acting, non-opioid benzoxazocine with analgesic activity.
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