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Search Results for "erk"

Targets

Libraries

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Compounds

Cat No. Product Name
TP1897L1 JIP-1 (153-163) acetate(438567-88-5 free base) JNK
Peptide inhibitor of c-Jun N-terminal kinase (JNK), based on residues 153-163 of JNK-interacting protein-1 (JIP-1). Bind...
T2845 Imperatorin Ammidin , 8-Isopentenyloxypsoralene , Marmelosin , 8-Isoamylenoxypsoralen , Pentosalen TRP/TRPV Channel , AChR , AChE , NOD
Imperatorin is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density...
TMS2181 Trans-Zeatin (E)-Zeatin Endogenous Metabolite , ERK , MEK
Trans-Zeatina is the member of the plant growth hormone family known as cytokinins, which regulate cell division, develo...
T9428 HM43239 FLT
HM43239 is an orally active and selective FLT3 inhibitor with IC 50 s of 1.1 nM, 1.8 nM and 1.0 nM for FLT3 WT, FLT3 int...
T2171 SEW​2871 SEW2871 S1P Receptor , LPL Receptor
Sphingosine-1-phosphate receptor 1 agonist SEW2871 prolongs heterotopic heart allograft survival in mice.
T6920 ON123300 c-RET , FGFR , JAK , AMPK , Src , PDGFR , CDK
ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM...
T2940 6-Hydroxyflavone 6-HF GABA Receptor
6-Hydroxyflavone is a noncompetitive inhibitors of cytochrome P450 2C9. It is a flavone, a type of chemical compound. It...
T3856 Tenuifoliside A Others , ERK
Tenuifoliside A has anti-apoptotic , neuroprotective activity. And tenuifoliside A has anti-inflammatory effect, which i...
TQ0138 K145 hydrochloride Apoptosis , S1P Receptor
K145 is a specific inhibitor of SphK2 (IC50: 4.30 μM), while no inhibition of SphK1 at concentrations up to 10 μM.
T5S1058 Triptonide PG 492 , NSC 165677 Apoptosis , Wnt/beta-catenin , Autophagy
1. Triptonide is effective in the treatment of autoimmune diseases and has potent antileukemic and antitumor activities....
T23046 N-tert-butyl-α-Phenylnitrone (Z)-N-benzylidene-2-Methylpropan-2-aMine oxide ROS , COX
COX-2 inhibitor
T0860L Mefloquine Ro215998 , Ro-215998 , Ro 215998 , WR 142490 , Lariam Others
Mefloquine is a phospholipid-interacting antimalarial drug effective against Plasmodium Falciparium with very few side e...
T11225 ERK-IN-2 ERK
ERK-IN-2 is a ERK2 inhibitor with an IC 50 value of 1.8 nM. ERK-IN-2 might cause off-target toxicity and/or off-target a...
T39726 SHP389
SHP389 is an allosteric SHP2 inhibitor, with an IC 50 of 36 nM for both SHP2 and p-ERK.
T39159 Edaxeterkib
Edaxeterkib is a potent extracellular signal- regulated kinase (ERK) inhibitor for the research of cancer.
T61122 ZINC12409120
ZINC12409120 is a high selective ERK inhibitor. ZINC12409120 acts on disrupting FGF23:α-Klotho interaction to inhibit ER...
T17261 Xantocillin Others
Xanthocillin is a marine agent. Xanthocillin also induces autophagy through inhibition of the MEK/ERK pathway.
T27654 JG26 JG-26 , JG 26
JG26 is an ADAM17 inhibitor. JG26 inhibits AngII-induced EGFR transactivation and ERK activation in vascular smooth musc...
T28140 NCG21 NCG 21 , NCG-21
NCG21 is a GPR120 agonist, which showed potent extracellular signal-regulated kinase (ERK) activation in a cloned GPR120...
T60821 ACA-28
ACA-28 (compound 2a) is a potent modulator of ERK MAPK signaling that induces apoptosis with ERK hyperactivation therefo...
JIP-1 (153-163) acetate(438567-88-5 free base)
TP1897L1
synonym:
Target:
Imperatorin
T2845
synonym: Ammidin , 8-Isopentenyloxypsoralene , Marmelosin , 8-Isoamylenoxypsoralen , Pentosalen
Target:
trans-Zeatin
TMS2181
synonym: (E)-Zeatin
Target:
HM43239
T9428
synonym:
Target:
SEW​2871
T2171
synonym: SEW2871
Target:
ON123300
T6920
synonym:
Target:
6-Hydroxyflavone
T2940
synonym: 6-HF
Target:
Tenuifoliside A
T3856
synonym:
Target:
K145 hydrochloride
TQ0138
synonym:
Target:
Triptonide
T5S1058
synonym: PG 492 , NSC 165677
Target:
N-tert-butyl-α-Phenylnitrone
T23046
synonym: (Z)-N-benzylidene-2-Methylpropan-2-aMine oxide
Target:
Mefloquine
T0860L
synonym: Ro215998 , Ro-215998 , Ro 215998 , WR 142490 , Lariam
Target:
ERK-IN-2
T11225
synonym:
Target:
SHP389
T39726
synonym:
Target:
Edaxeterkib
T39159
synonym:
Target:
ZINC12409120
T61122
synonym:
Target:
Xantocillin
T17261
synonym:
Target:
JG26
T27654
synonym: JG-26 , JG 26
Target:
NCG21
T28140
synonym: NCG 21 , NCG-21
Target:
ACA-28
T60821
synonym:
Target:
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