T62814 |
Antitumor agent-77
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Antitumor agent-77 对癌细胞的生长和迁移具有抑制作用,具有抗癌作用。Antitumor agent-77 能够抑制 GPx-4 和提高 COX2 引发铁下垂。Antitumor agent-77 可以激活肿瘤细胞固有凋亡通... |
TN1837 |
Kuguaglycoside C
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苦瓜皂苷 C |
Caspase
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PARP
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Kuguaglycoside C induces caspase-independent cell death, and is involved, at least in part, in the mechanism underlying ... |
T40602 |
Z-LEHD-FMK TFA
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Z-LEHD-FMK TFA is a specific and irreversible inhibitor of caspase-9, offering protection against detrimental reperfusio... |
T71839 |
ATV399
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ATV399 is an inhibitor of iNOS dimerization which protects against Cytokine-Induced rat β-cell dysfunction, thereby inhi... |
T38637 |
Roy-Bz
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Roy-Bz is a potent and selective activator of protein kinase C delta (PKCδ). It effectively inhibits proliferation in co... |
T27174 |
Dihydrocelastrol
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DHCE. (-)-Triptohypol C,Triptohypol C |
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Dihydrocelastrol is synthesized by hydrogenation of celastrol, a treterpene isolated from Chinese medicinal plant Tripte... |
T13797 |
Nivalenol
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Caspase
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Nivalenol 是一种由禾谷镰刀菌产生的真菌代谢物。 Nivalenol 通过 caspase 和内在凋亡途径诱导细胞死亡,从而影响免疫系统并引起呕吐、生长迟缓和生殖障碍。 |
T25032 |
ALC67
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ALC 67,ALC-67 |
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ALC67 has a promising anticancer activity that results in the recent discovery of a series of 3-propionyl thiazolidine-4... |
T28017 |
Merbarone
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RLBN1001,NSC-336628,RLBN-1001,NSC336628 |
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Merbarone is a Type II DNA topoisomerase inhibitor. Merbarone inhibits the catalytic activity of human topoisomerase IIa... |
T70527 |
DAT-230
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DAT-230 is a promising microtubule inhibitor that has great potential for the treatment of fibrosarcoma in vitro and in ... |
T39909 |
XZ739
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XZ739 |
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XZ739 is a Cereblon-dependent PROTAC BCL-XL degrader, targeting a member of the Bcl-2 family, with a DC50 value of 2.5 n... |
T28275 |
OUP-186
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OUP186 |
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OUP-186 is a high affinity and human/rat species-selective antagonist of histamine H3 receptor. OUP-186 suppressed the p... |
T63001 |
Antitumor agent-72
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Antitumor agent-72 是一种有效的抗癌剂。Antitumor agent-72 具有抗癌活性,并通过激活 caspase-3 和裂解PARP 诱导细胞凋亡 (apoptosis)。Antitumor agent-72 可用于... |
TN4903 |
Regiolone
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Caspase
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Regiolone demonstrates phytotoxicity. Regiolone also has anti-proliferative and apoptotic activities, it can induce apop... |
T61428 |
4-PQBH
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4-PQBH is a potent binder of Nur77, with a binding affinity of 1.17 μM. It promotes caspase-independent cytoplasmic vacu... |
T13764 |
Lycopodine
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Lipoxygenase
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Caspase
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Lycopodine, a bioactive compound derived from Lycopodium clavatum spores, effectively inhibits the proliferation of HeLa... |
T76288 |
GPR
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GPR 是一种三氨基酸肽。GPR 可以通过抑制caspase-3/p53依赖性细胞凋亡来拯救培养的大鼠海马神经元免受 Aβ 诱导的神经元死亡。GPR 可用于阿尔茨海默病(AD)的研究。 |
T73876 |
Sanggenon G
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Sanggenon G 是一种具有细胞渗透性的有效的 X 连锁凋亡抑制蛋白 (XIAP) 抑制剂。Sanggenon G 特异性结合XIAP 的 BIR3 结构域,结合亲和力为 34.26 μM。Sanggenon G 增强caspase ... |
T13445 |
(R)-Q-VD-OPh
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(R)-QVD-OPH,(R)-Quinoline-Val-Asp-Difluorophenoxymethylketone |
Others
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(R)-Q-VD-OPh is the less active enantiomer of Q-VD-OPha. Q-VD-OPha is an irreversible inhibitor of pan-caspase, with pot... |
TN5033 |
Skullcapflavone I
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IL Receptor
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Caspase
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Prostaglandin Receptor
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Skullcapflavone I has anti-inflammatory and anti-allergic potential, it can significantly inhibit LPS stimulated NO and ... |