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Calcium Channel

A calcium channel is an ion channel which shows selective permeability to calcium ions. It is sometimes synonymous with voltage-gated calcium channel, although there are also ligand-gated calcium channels.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T19882 Bryonolic acid 24480-45-3 99.93%
Bryonolic acid
Bryonolic acid (20-epi-Bryonolic acid), a triterpenoid extracted from Sandoricum indicum, possesses immunomodulatory, anti-inflammatory, antioxidant and anticanc...
T7285 Ionomycin 56092-81-0 99.54%
Ionomycin
Ionomycin is an calcium ionophore and an antibiotic that binds calcium ions (Ca2+). It is produced by the bacterium Streptomyces conglobatus.It is used in resea...
T12076L ML218 1346233-68-8 99.45%
ML218
ML218 is an orally active, selective, potent, and blood-brain barrier-crossing inhibitor of T-type Ca2+ channels (Cav3.1, Cav3.2, Cav3.3) (IC50 for Cav3.2 and Ca...
T11731L JTV-519 Formate 99.06%
JTV-519 Formate
JTV-519 Formate is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA). JTV-519 Formate is also a partial agonist of ryanodine rece...
T13684 Equilin 474-86-2 98.57%
Equilin
Equilin (7-Dehydroestrone) is a neurotrophic estrogenic steroid with vasodilatory activity that increases monocyte-endothelial adhesion through NF-κB signalling....
T36812 Linoleic Acid Amide 3999-01-7 98.53%
Linoleic Acid Amide
Linoleic Acid Amide (Linoleamide) is derived from linoleic acid and regulates Ca2+ flux by inhibiting the sarco/endoplasmic reticulum Ca2+-ATPase.
T68125 (Rac)-PD0299685 313651-02-4 97.20%
(Rac)-PD0299685
(Rac)-PD0299685 is a potent voltage-dependent calcium channel inhibitor for the study of retina-related diseases.
TN1338 7Beta-Hydroxycholesterol 566-27-8 98%
7Beta-Hydroxycholesterol
7beta-Hydroxycholesterol, a major cytotoxin in oxidized LDL, induces Ca(2+) oscillations, MAP kinase activation and apoptosis in human aortic smooth muscle cells...
TN3660 Cinnamyl caffeate 115610-32-7 98%
Cinnamyl caffeate
Cinnamyl caffeate has cardiovascular protective effects, it can increase H9c2 cellular antioxidant potential, decrease intracellular calcium ion ([Ca2+]i) level,...
TN3042 4-Hydroxycinnamamide 194940-15-3 98%
4-Hydroxycinnamamide
4-Hydroxycinnamamide has antioxidant activity. 4-Hydroxycinnamamide derivatives are specific inhibitors of tyrosine-specific protein kinases.
T78066 BBT 445000-45-3 98%
BBT
BBT enhances glucose-stimulated insulin secretion (GSIS) in compromised conditions, demonstrates anti-hyperglycemia effects, and shields β-cells from cytokine- o...
T78626 LY393615 98%
LY393615
LY393615 (NCC1048) is a novel blocker of both neuronal Ca²⁺ (calcium) and Na⁺ (sodium) channels, exhibiting half-maximal inhibitory concentrations (IC₅₀) of 1.9 ...
T78714 PptT-IN-4 98%
PptT-IN-4
PptT-IN-4 (Compound 3a) is a PptT inhibitor exhibiting an IC50 of 0.71 μM. It also demonstrates antimycobacterial activity against Mtb H37Rv, with a MIC of 42 μM...
T79195 Cav 3.2 inhibitor 4 1416984-93-4 98%
Cav 3.2 inhibitor 4
Cav 3.2 Inhibitor 4 (Compound 21) is a selective and potent inhibitor of the T-type calcium channel (Ca v 3.2), demonstrating peripheral restriction with an IC50...
T80063 Imperatoxin A 172451-37-5 98%
Imperatoxin A
Imperatoxin A, a peptide toxin sourced from the African scorpion Pandinus imperator, functions as an activator of Ca2+-release channels/ryanodine receptors (RyRs...
T80065 Calcicludine 178036-64-1 98%
Calcicludine
Calcicludine, a protein toxin derived from the green mamba (Dendroaspis angusticeps) venom, selectively inhibits high-voltage-activated, particularly L-type, cal...
T80078 Calciseptin 178805-91-9 98%
Calciseptin
Calciseptine, a neurotoxin isolated from the Black Mamba (Dendroaspis p. polylepis) venom, comprises 60 amino acids and is stabilized by four disulfide bonds. It...
T80153 Maurocalcine 269745-22-4 98%
Maurocalcine
Maurocalcine is a cell-permeable agonist for ryanodine receptor (RyR) subtypes 1, 2, and 3. It enhances [3 H]ryanodine binding to RyR1 with an EC50 of 2558 nM an...
T80158 ω-Tbo-IT1 98%
ω-Tbo-IT1
ω-Tbo-IT1, a peptide toxin extracted from the venom of Tibellus oblongus, functions as an inhibitor of insect calcium channels [1].
T80160 ω-Hexatoxin-Hv1a 193981-10-1 98%
ω-Hexatoxin-Hv1a
ω-Hexatoxin-Hv1a, a neurotoxin extracted from the venom of the spider Hadronyche versuta, inhibits voltage-gated calcium channels [1] [2].
Bryonolic acid
T19882
Bryonolic acid (20-epi-Bryonolic acid), a triterpenoid extracted from Sandoricum indicum, possesses immunomodulatory, anti-inflammatory, antioxidant and anticanc...
Ionomycin
T7285
Ionomycin is an calcium ionophore and an antibiotic that binds calcium ions (Ca2+). It is produced by the bacterium Streptomyces conglobatus.It is used in resea...
ML218
T12076L
ML218 is an orally active, selective, potent, and blood-brain barrier-crossing inhibitor of T-type Ca2+ channels (Cav3.1, Cav3.2, Cav3.3) (IC50 for Cav3.2 and Ca...
JTV-519 Formate
T11731L
JTV-519 Formate is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA). JTV-519 Formate is also a partial agonist of ryanodine rece...
Equilin
T13684
Equilin (7-Dehydroestrone) is a neurotrophic estrogenic steroid with vasodilatory activity that increases monocyte-endothelial adhesion through NF-κB signalling....
Linoleic Acid Amide
T36812
Linoleic Acid Amide (Linoleamide) is derived from linoleic acid and regulates Ca2+ flux by inhibiting the sarco/endoplasmic reticulum Ca2+-ATPase.
(Rac)-PD0299685
T68125
(Rac)-PD0299685 is a potent voltage-dependent calcium channel inhibitor for the study of retina-related diseases.
7Beta-Hydroxycholesterol
TN1338
7beta-Hydroxycholesterol, a major cytotoxin in oxidized LDL, induces Ca(2+) oscillations, MAP kinase activation and apoptosis in human aortic smooth muscle cells...
Cinnamyl caffeate
TN3660
Cinnamyl caffeate has cardiovascular protective effects, it can increase H9c2 cellular antioxidant potential, decrease intracellular calcium ion ([Ca2+]i) level,...
4-Hydroxycinnamamide
TN3042
4-Hydroxycinnamamide has antioxidant activity. 4-Hydroxycinnamamide derivatives are specific inhibitors of tyrosine-specific protein kinases.
BBT
T78066
BBT enhances glucose-stimulated insulin secretion (GSIS) in compromised conditions, demonstrates anti-hyperglycemia effects, and shields β-cells from cytokine- o...
LY393615
T78626
LY393615 (NCC1048) is a novel blocker of both neuronal Ca²⁺ (calcium) and Na⁺ (sodium) channels, exhibiting half-maximal inhibitory concentrations (IC₅₀) of 1.9 ...
PptT-IN-4
T78714
PptT-IN-4 (Compound 3a) is a PptT inhibitor exhibiting an IC50 of 0.71 μM. It also demonstrates antimycobacterial activity against Mtb H37Rv, with a MIC of 42 μM...
Cav 3.2 inhibitor 4
T79195
Cav 3.2 Inhibitor 4 (Compound 21) is a selective and potent inhibitor of the T-type calcium channel (Ca v 3.2), demonstrating peripheral restriction with an IC50...
Imperatoxin A
T80063
Imperatoxin A, a peptide toxin sourced from the African scorpion Pandinus imperator, functions as an activator of Ca2+-release channels/ryanodine receptors (RyRs...
Calcicludine
T80065
Calcicludine, a protein toxin derived from the green mamba (Dendroaspis angusticeps) venom, selectively inhibits high-voltage-activated, particularly L-type, cal...
Calciseptin
T80078
Calciseptine, a neurotoxin isolated from the Black Mamba (Dendroaspis p. polylepis) venom, comprises 60 amino acids and is stabilized by four disulfide bonds. It...
Maurocalcine
T80153
Maurocalcine is a cell-permeable agonist for ryanodine receptor (RyR) subtypes 1, 2, and 3. It enhances [3 H]ryanodine binding to RyR1 with an EC50 of 2558 nM an...
ω-Tbo-IT1
T80158
ω-Tbo-IT1, a peptide toxin extracted from the venom of Tibellus oblongus, functions as an inhibitor of insect calcium channels [1].
ω-Hexatoxin-Hv1a
T80160
ω-Hexatoxin-Hv1a, a neurotoxin extracted from the venom of the spider Hadronyche versuta, inhibits voltage-gated calcium channels [1] [2].
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TargetMol