Search Result

Search Results for "caspase"

Targets

Libraries

Pyroptosis Compound Library Endoplasmic Reticulum Stress Compound Library

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Compounds

Cat No.	Product Name
TQ0146L	Caspase-3 Inhibitor I	Ac-DEVD-CHO acetate (169332-60-9 free base) , N-acetyl-asp-glu-val-asp-al	Caspase
	Caspase-3 Inhibitor I is a specific inhibitor of Caspase-3.		Caspase
T10580	BOC-D-FMK		Caspase , Apoptosis
	Boc-D-FMK is an irreversible, cell-permeable, and broad-spectrum caspase inhibitor and inhibits apoptosis stimulated by ...		Caspase , Apoptosis
T7816	Ac-DEVD-pNA		Others
	Ac-DEVD-pNA is the preferred peptidic substrate for caspase-3.		Others
T8468	CIL62		Caspase
	CIL62 is a caspase-3/7-independent cell death inducer. The mechanism of action of CIL62 is Necrostatin-1 dependent cell ...		Caspase
T14298	Rimiducid		Apoptosis , Others , Fatty Acid Synthase
	Rimiducid is a lipid-permeable tacrolimus analogue, homodimerizing an analogue of human protein fkbp12 and binding to wi...		Apoptosis , Others , Fatty Acid Synthase
T10896L	CSRM617 hydrochloride	CSRM617 hydrochloride(787504-88-5 Free base)	Others , Apoptosis , Androgen Receptor
	CSRM617 hydrochloride is a selective small-molecule inhibitor of the transcription factor ONECUT2 ( OC2, a master regula...		Others , Apoptosis , Androgen Receptor
T7452	2-methoxycinnamaldehyde	O-methoxycinnamaldehyde	Others , Apoptosis
	2-Methoxycinnamaldehyde (2-MCA) is a natural compound of Cinnamomum cassia,has been widely studied with regard to its an...		Others , Apoptosis
T3701	MCC950	CP-456773	NOD
	CP-456773 (MCC950 and CRID3) is an effective and specific cytokine release inhibitor and NLRP3 inflammasome inhibitor. C...		NOD
T6275	Obatoclax Mesylate	Obatoclax , GX15-070	BCL , Autophagy , Parasite
	Obatoclax is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c r...		BCL , Autophagy , Parasite
T1555	Diclofenac sodium	GP 45840	Apoptosis , COX
	Diclofenac sodium is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is prima...		Apoptosis , COX
T5558	Chelidonic acid	γ-Pyrone-2,6-dicarboxylic acid , Jerva acid , Jervaic acid	NF-κB , Caspase
	Chelidonic acid is a component of Chelidonium majus L., used as a mild analgesic, an antimicrobial, an acentral nervous ...		NF-κB , Caspase
T3786	Tomatine	lycopersicin	Apoptosis , Proteasome
	An antiproliferatve agent of breast adenocarcinoma cells.		Apoptosis , Proteasome
T1979	AVN-944	VX-944	Dehydrogenase
	AVN-944(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2.		Dehydrogenase
T2503	PAC-1	Procaspase activating compound 1	Apoptosis , Caspase , Autophagy
	PAC-1 has been used in trials studying the treatment of Lymphoma, Melanoma, Solid Tumors, Breast Cancer, and Thoracic Ca...		Apoptosis , Caspase , Autophagy
T38562	AKN-028		FLT
	AKN-028 is an orally active and potent FLT3 tyrosine kinase inhibitor ( IC 50 = 6 nM). AKN-028 causes dose-dependent in...		FLT
T21871	Caspase-3/7 Inhibitor I
	MMPSI is a potent and selective small molecule caspase 3 and caspase 7 inhibitor with an IC 50 of 1.7 μM for human caspa...
T24903	TRP-601	TRP601
	TRP-601 is a caspase inhibitor.
T31040	CP-18 F-18	CP 18 F-18 , CP18 F-18 , (18F)-CP18
	CP-18 F-18 is a DEVD (the caspase 3 substrate recognition motif) that is an imaging tracer for caspase-3 activity in apo...
T23555	Z-VEID-FMK		Others
	When compared to other caspase inhibitors, Z-DRHD-FMK inhibited caspase 6 activity more effectively than the general cas...		Others
T36354	Suc-YVAD-AMC (acetate)
	Suc-YVAD-AMC is a fluorogenic substrate for caspase-1. Upon enzymatic cleavage by caspase-1, 7-amino-4-methylcoumarin (A...