TN4605 |
Myriceric acid B
|
55497-79-5
|
98%
|
|
Myriceric acid B is a potent HIV-1 entry inhibitor targeting gp41 and can serve as a lead compound for developing novel anti-HIV-1 drug. Myriceric acid B scaveng...
|
T14208 |
AMD 3465
|
185991-24-6
|
98%
|
|
AMD 3465 also potently inhibits the replication of X4 HIV strains (IC50: 1-10 nM). However, it has no effect on CCR5-using (R5) viruses. AMD 3465 (GENZ-644494) i...
|
T0742 |
Papaverine hydrochloride
|
61-25-6
|
98%
|
|
Papaverine hydrochloride can used in an effective manner in the management of renal colic pain in patients unresponsive to commonly used conventional agents. Pap...
|
T6589 |
MK-2048
|
869901-69-9
|
98%
|
|
MK-2048 is a potent inhibitor of integrase (IN) and INR263K with IC50 of 2.6 nM and 1.5 nM, respectively.
|
TN2284 |
Triptonine B
|
168009-85-6
|
98%
|
|
Triptonine B demonstrates potent anti-HIV activity with an EC(50) value of <0.10 microg/mL and an in vitro therapeutic index value of >1000.
|
T60742 |
HIV-1 integrase inhibitor 8
|
1568-80-5
|
98%
|
|
HIV-1 integrase inhibitor 8 is a HIV-1 integrase inhibitor.
|
T16112 |
ML67-33
|
1443290-89-8
|
98%
|
|
ML67-33 rapidly and reversibly affects K2P2.1 (TREK-1) (EC50s: 36.3 μM and 9.7 μM in cell-free and HEK293 cells, respectively). ML67-33 is a selective activator ...
|
TN3567 |
Calanolide E
|
142566-61-8
|
98%
|
|
Calanolide E2 has anti-HIV activity.
|
T16555 |
PNU-103017
|
166335-18-8
|
98%
|
|
PNU-103017 is an inhibitor of HIV protease.
|
TN1708 |
Gomisin M2
|
82425-45-4
|
98%
|
|
Gomisin M2 is an anti-HIV agent.
|
TN3152 |
6-Acetonyldihydrochelerythrine
|
22864-92-2
|
98%
|
|
6-Acetonyldihydrochelerythrine exhibits significant antioxidant activities, it exhibits significant anti-HIV activity in H9 lymphocytes with EC50 and TI (Therape...
|
TN2186 |
Schisantherin D
|
64917-82-4
|
98%
|
|
Schisantherin D shows good anti-HIV activity with the EC50 value of 0.5 micrograms/mL, and the therapeutic index (TI) value of 110.
|
T10658 |
CA inhibitor 1
|
2189684-45-3
|
98%
|
|
CA inhibitor 1 (GS-6207 analog) is a potent inhibitor of the HIV capsid.
|
T16829 |
(S)-BI-1001
|
957889-73-5
|
98%
|
|
(S)-BI-1001 is an active S-enantiomer of BI-1001. (S)-BI-1001 has antiviral potency against HIV-1 integrase (IC50: 28 nM, and EC50: 450 nM and a Kd: 4.7 μM).
|
T5S0983 |
Absinthin
|
1362-42-1
|
98%
|
|
1. Absinthiin is a weak HIV-1 protease inhibitor.
|
TN5177 |
Trigothysoid N
|
1501943-08-3
|
98%
|
|
Trigothysoid N may have anti-HIV activity.
|
T10928 |
Cytochalasin A
|
14110-64-6
|
98%
|
|
Cytochalasin A is a cell-permeable fungal toxin and is an oxidized derivative of cytochalasin B. Cytochalasin A is an inhibitor of HIV-1 protease (IC50 = 3 μM), ...
|
TN2231 |
Soyasaponin II
|
55319-36-3
|
98%
|
|
Soyasaponin II has antiviral effects, it can inhibit the replication of human cytomegalovirus, influenza virus, and human immunodeficiency virus type 1.
|
T14831 |
Bryostatin 1
|
83314-01-6
|
98%
|
|
Bryostatin 1 is a natural macrolide isolated from the bryozoan Bugula neritina and is a CNS)permeable PKC modulator. Bryostatin 1 binds to the isolated C1 domain...
|
TN1194 |
16beta,17-Dihydroxy-ent-kaurane-19-oic acid
|
74365-74-5
|
98%
|
|
16beta,17-Dihydroxy-ent-kaurane-19-oic acid as an anti-HIV principle, it showed significant activity against HIV replication in H9 lymphocyte cells with an EC50 ...
|