T5S0983 |
Absinthin
|
1362-42-1
|
|
|
1. Absinthiin is a weak HIV-1 protease inhibitor.
|
TN2186 |
Schisantherin D
|
64917-82-4
|
98%
|
|
Schisantherin D shows good anti-HIV activity with the EC50 value of 0.5 micrograms/mL, and the therapeutic index (TI) value of 110.
|
T14208 |
AMD 3465
|
185991-24-6
|
98%
|
|
AMD 3465 also potently inhibits the replication of X4 HIV strains (IC50: 1-10 nM). However, it has no effect on CCR5-using (R5) viruses. AMD 3465 (GENZ-644494) i...
|
T16829 |
(S)-BI-1001
|
957889-73-5
|
98%
|
|
(S)-BI-1001 is an active S-enantiomer of BI-1001. (S)-BI-1001 has antiviral potency against HIV-1 integrase (IC50: 28 nM, and EC50: 450 nM and a Kd: 4.7 μM).
|
TN4347 |
Jacoumaric acid
|
63303-42-4
|
98%
|
|
Jacoumaric acid is a lead molecule from the library or database of natural compounds as a HIV-1 protease inhibitor.
|
TN3567 |
Calanolide E
|
142566-61-8
|
98%
|
|
Calanolide E2 has anti-HIV activity.
|
TN4433 |
Licoarylcoumarin
|
125709-31-1
|
98%
|
|
Licoarylcoumarin is a strong inhibitor of adenosine 3',5'-cyclic monophosphate (cAMP) phosphodiesterase. Licoarylcoumarin has antibacterial effects on the VRE st...
|
TN5243 |
Vitexilactone
|
61263-49-8
|
98%
|
|
Vitexilactone is a HIV-1 reverse transcriptase inhibitor in virtual screening against Indonesian Herbal Database using AutoDock4 performed on HIV-1 reverse trans...
|
T2S0605 |
Liquidambaric lactone
|
185051-75-6
|
98%
|
|
Liquidambaric lactone is a compound isolated from Euonymus grandiflorus Wall.Liquidambaric lactone may have inhibitory HIV-1 reverse transcriptase activity.
|
TN1767 |
InteriotherinA
|
181701-06-4
|
98%
|
|
Interiotherin A inhibits HIV replication with the EC50 value of 3.1 micrograms/mL.
|
TN1235 |
3,4,5-Tricaffeoylquinic acid
|
86632-03-3
|
98%
|
|
3,4,5-Tricaffeoylquinic acid may attenuate the TNF-α±- and LPS-stimulated production of inflammatory mediators in keratinocytes by suppressing the Toll-like rece...
|
TN4820 |
Pre-schisanartanin B
|
1033288-92-4
|
98%
|
|
Pre-schisanartanin B has cytotoxicity, it also has anti-HIV-1 activity.
|
TN5011 |
Shizukaol B
|
142279-40-1
|
98%
|
|
Shizukaol B exerts anti-inflammatory effects in LPS-activated microglia partly by modulating JNK-AP-1 signaling pathway; it also shows significant anti-neuroinfl...
|
T10658 |
CA inhibitor 1
|
2189684-45-3
|
98%
|
|
CA inhibitor 1 (GS-6207 analog) is a potent inhibitor of the HIV capsid.
|
T14488 |
Azt-pmap
|
142629-81-0
|
98%
|
|
Azt-pmap shows anti-HIV activity[1]. Azt-pmap, a nucleoside analogue, is an aryl phosphate derivative of AZT. AZT is a nucleoside reverse transcriptase inhibitor...
|
TN3705 |
Coronalolide methyl ester
|
268214-50-2
|
98%
|
|
Coronalolide methyl ester displays significant anti-HIV activities in the HIV-1RT assay. It and coronalolide show broad cytotoxic activity against a panel of hum...
|
TN4555 |
Methyl salvionolate A
|
1015171-69-3
|
98%
|
|
Methyl salvionolate A has anti-HIV-1 activity.
|
TN4109 |
Ganolucidic acid A
|
98665-21-5
|
98%
|
|
Ganolucidic acid A exhibits cytotoxicity, has inhibitory activities against human HeLa cervical cancer cell lines. It shows significant anti-human immunodeficien...
|
TN4646 |
Neotripterifordin
|
149249-32-1
|
98%
|
|
Neotripterifordin shows potent anti-HIV replication activity in H9 lymphocyte cells with an EC50 of 25 nM and TI of 125.
|
TN4585 |
Moronic acid
|
6713-27-5
|
98%
|
|
Moronic acid shows oral therapeutic efficacy in HSV-infected mice and possessed novel anti-HSV activity. It also shows significant anti-HIV activity (EC(50) 186)...
|