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Search Results for "akt"

Targets

Libraries

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Compounds

Cat No. Product Name
T38737L SDKPDMAEIEKFDKSK acetate SDKPDMAEIEKFDKSK acetate(1339864-27-5 free base) Others
SDKPDMAEIEKFDKSK acetate is a thymosin β4 derivative. Thymosin β4 inhibits PDGF-BB-induced fibrogenesis, proliferation a...
T9156 CDC25B-IN-2 Phosphatase , mTOR
BIA is an inhibitor of the interaction between TMBIM6 and mTORC2, which ultimately blocks AKT activation and cancer prog...
T33296 Merodantoin Apoptosis
Merodantoin is an apoptosis inducer and triggers cell apoptosis associated with ROS-dependent autophagy. Merodantoin tar...
T28072 MLN-3897 AVE-9897 , CCR1 antagonist 10 CCR
MLN-3897 is an orally active antagonist of CCR1 with a Ki of 2.3 nM for 125I-MIP-1α binding to THP-1 cell membranes. MLN...
T4444 A-674563 HCl (552325-73-2(free base)) ERK , Akt , PKA , PKC , CDK
A-674563 is an orally available, ATP-competitive, and reversible inhibitor of Akt (Ki: 11 nM for Akt1) [1]. It exhibits ...
T9996 NCT-58 NCT58 HSP
NCT-58 is a potent C-terminal HSP90 inhibitor. NCT-58 does not induce the heat shock response (HSR). NCT-58 elicits ant...
T35528L TD52 dihydrochloride TD52 dihydrochloride(1798328-24-1 Free base) , TD52 2HCl Others
TD52 dihydrochloride, an Erlotinib derivative, is an orally active, potent cancerous inhibitor of protein phosphatase 2A...
T2171 SEW​2871 SEW2871 S1P Receptor , LPL Receptor
Sphingosine-1-phosphate receptor 1 agonist SEW2871 prolongs heterotopic heart allograft survival in mice.
T6429 Caffeic Acid Phenethyl Ester CAPE , Phenylethyl Caffeate NF-κB , Apoptosis
Caffeic Acid Phenethyl Ester (CAPE) inhibits the activation of nuclear transcription factor NF-kappa B and may suppress ...
T6920 ON123300 c-RET , FGFR , JAK , AMPK , Src , PDGFR , CDK
ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM...
T4S1419 (±)-Praeruptorin A Praeruptorin A , (-)-Praeruptorin A Calcium Channel , p38 MAPK , Akt
1. Praeruptorin A could exhibit its anti-osteoclastogenic activity by inhibiting p38/Akt-c-Fos-NFATc1 signaling and PLCγ...
T3800 Typhaneoside Aervitrin Others , Autophagy
Typhaneoside is a flavonoid glycoside plant extract with potential ability to treat primary dysmenorrhea through the Sha...
T2940 6-Hydroxyflavone 6-HF GABA Receptor
6-Hydroxyflavone is a noncompetitive inhibitors of cytochrome P450 2C9. It is a flavone, a type of chemical compound. It...
TL0006 Cichoric Acid Chicoric Acid , Dicaffeoyltartaric acid Reactive Oxygen Species , HIV Protease
Chicoric Acid is a potent inhibitor of human immunodeficiency virus type-1 (HIV-1) integrase and the replication in tiss...
T2746 Sophocarpine monohydrate Sophocarpine Apoptosis , Influenza Virus , Akt , PI3K , Autophagy , AMPK
Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.
TQ0138 K145 hydrochloride Apoptosis , S1P Receptor
K145 is a specific inhibitor of SphK2 (IC50: 4.30 μM), while no inhibition of SphK1 at concentrations up to 10 μM.
T9831 MKC-1 inhibit , mTOR , Apoptosis , Protein kinase B , PKB , MKC 1 , renal cell cancer , Caki-1 , Ro-31-7453 , Mammalian target of Rapamycin , orally active , Microtubule/Tubulin , MKC-1 , Akt , pancreatic cancer , Inhibitor , MKC1 Akt , Microtubule Associated , Apoptosis , mTOR
MKC-1 is an orally bioavailable, small-molecule, bisindolylmaleimide cell cycle inhibitor with potential antineoplastic ...
T5429 Theaflavin 3,3'-digallate 8-Gingerol , TFDG HIV Protease , Virus Protease , Antioxidant , HSV
8-Gingerol (TFDG), a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory ...
T61680 AKT-IN-5
AKT-IN-5 (Example 8) is a Akt inhibitor with IC 50 values of 450 nM and 400 nM for Akt1 and Akt2, respectively [1].
T61756 APN/AKT-IN-1
APN/AKT-IN-1 is a potent and dual inhibitor of APN and AKT with IC 50 s of 0.21 and 0.27 μM, respectively. APN/AKT-IN-1 ...
SDKPDMAEIEKFDKSK acetate
T38737L
synonym: SDKPDMAEIEKFDKSK acetate(1339864-27-5 free base)
Target:
CDC25B-IN-2
T9156
synonym:
Target:
Merodantoin
T33296
synonym:
Target:
MLN-3897
T28072
synonym: AVE-9897 , CCR1 antagonist 10
Target:
A-674563 HCl (552325-73-2(free base))
T4444
synonym:
Target:
NCT-58
T9996
synonym: NCT58
Target:
TD52 dihydrochloride
T35528L
synonym: TD52 dihydrochloride(1798328-24-1 Free base) , TD52 2HCl
Target:
SEW​2871
T2171
synonym: SEW2871
Target:
Caffeic Acid Phenethyl Ester
T6429
synonym: CAPE , Phenylethyl Caffeate
Target:
ON123300
T6920
synonym:
Target:
(±)-Praeruptorin A
T4S1419
synonym: Praeruptorin A , (-)-Praeruptorin A
Target:
Typhaneoside
T3800
synonym: Aervitrin
Target:
6-Hydroxyflavone
T2940
synonym: 6-HF
Target:
Cichoric Acid
TL0006
synonym: Chicoric Acid , Dicaffeoyltartaric acid
Target:
Sophocarpine monohydrate
T2746
synonym: Sophocarpine
Target:
K145 hydrochloride
TQ0138
synonym:
Target:
MKC-1
T9831
synonym: inhibit , mTOR , Apoptosis , Protein kinase B , PKB , MKC 1 , renal cell cancer , Caki-1 , Ro-31-7453 , Mammalian target of Rapamycin , orally active , Microtubule/Tubulin , MKC-1 , Akt , pancreatic cancer , Inhibitor , MKC1
Target:
Theaflavin 3,3'-digallate
T5429
synonym: 8-Gingerol , TFDG
Target:
AKT-IN-5
T61680
synonym:
Target:
APN/AKT-IN-1
T61756
synonym:
Target:
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