Search Result

Search Results for "akt"

Targets

Libraries

PI3K-AKT-mTOR Compound Library Clinical Compound Library HIF-1 Signaling Pathway Compound Library Anti-Breast Cancer Compound Library

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Compounds

Cat No.	Product Name
T38737L	SDKPDMAEIEKFDKSK acetate	SDKPDMAEIEKFDKSK acetate(1339864-27-5 free base)	Others
	SDKPDMAEIEKFDKSK acetate is a thymosin β4 derivative. Thymosin β4 inhibits PDGF-BB-induced fibrogenesis, proliferation a...		Others
T9156	CDC25B-IN-2		Phosphatase , mTOR
	BIA is an inhibitor of the interaction between TMBIM6 and mTORC2, which ultimately blocks AKT activation and cancer prog...		Phosphatase , mTOR
T33296	Merodantoin		Apoptosis
	Merodantoin is an apoptosis inducer and triggers cell apoptosis associated with ROS-dependent autophagy. Merodantoin tar...		Apoptosis
T28072	MLN-3897	AVE-9897 , CCR1 antagonist 10	CCR
	MLN-3897 is an orally active antagonist of CCR1 with a Ki of 2.3 nM for 125I-MIP-1α binding to THP-1 cell membranes. MLN...		CCR
T4444	A-674563 HCl (552325-73-2(free base))		ERK , Akt , PKA , PKC , CDK
	A-674563 is an orally available, ATP-competitive, and reversible inhibitor of Akt (Ki: 11 nM for Akt1) [1]. It exhibits ...		ERK , Akt , PKA , PKC , CDK
T9996	NCT-58	NCT58	HSP
	NCT-58 is a potent C-terminal HSP90 inhibitor. NCT-58 does not induce the heat shock response (HSR). NCT-58 elicits ant...		HSP
T35528L	TD52 dihydrochloride	TD52 dihydrochloride(1798328-24-1 Free base) , TD52 2HCl	Others
	TD52 dihydrochloride, an Erlotinib derivative, is an orally active, potent cancerous inhibitor of protein phosphatase 2A...		Others
T2171	SEW2871	SEW2871	S1P Receptor , LPL Receptor
	Sphingosine-1-phosphate receptor 1 agonist SEW2871 prolongs heterotopic heart allograft survival in mice.		S1P Receptor , LPL Receptor
T6429	Caffeic Acid Phenethyl Ester	CAPE , Phenylethyl Caffeate	NF-κB , Apoptosis
	Caffeic Acid Phenethyl Ester (CAPE) inhibits the activation of nuclear transcription factor NF-kappa B and may suppress ...		NF-κB , Apoptosis
T6920	ON123300		c-RET , FGFR , JAK , AMPK , Src , PDGFR , CDK
	ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM...		c-RET , FGFR , JAK , AMPK , Src , PDGFR , CDK
T4S1419	(±)-Praeruptorin A	Praeruptorin A , (-)-Praeruptorin A	Calcium Channel , p38 MAPK , Akt
	1. Praeruptorin A could exhibit its anti-osteoclastogenic activity by inhibiting p38/Akt-c-Fos-NFATc1 signaling and PLCγ...		Calcium Channel , p38 MAPK , Akt
T3800	Typhaneoside	Aervitrin	Others , Autophagy
	Typhaneoside is a flavonoid glycoside plant extract with potential ability to treat primary dysmenorrhea through the Sha...		Others , Autophagy
T2940	6-Hydroxyflavone	6-HF	GABA Receptor
	6-Hydroxyflavone is a noncompetitive inhibitors of cytochrome P450 2C9. It is a flavone, a type of chemical compound. It...		GABA Receptor
TL0006	Cichoric Acid	Chicoric Acid , Dicaffeoyltartaric acid	Reactive Oxygen Species , HIV Protease
	Chicoric Acid is a potent inhibitor of human immunodeficiency virus type-1 (HIV-1) integrase and the replication in tiss...		Reactive Oxygen Species , HIV Protease
T2746	Sophocarpine monohydrate	Sophocarpine	Apoptosis , Influenza Virus , Akt , PI3K , Autophagy , AMPK
	Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.		Apoptosis , Influenza Virus , Akt , PI3K , Autophagy , AMPK
TQ0138	K145 hydrochloride		Apoptosis , S1P Receptor
	K145 is a specific inhibitor of SphK2 (IC50: 4.30 μM), while no inhibition of SphK1 at concentrations up to 10 μM.		Apoptosis , S1P Receptor
T9831	MKC-1	inhibit , mTOR , Apoptosis , Protein kinase B , PKB , MKC 1 , renal cell cancer , Caki-1 , Ro-31-7453 , Mammalian target of Rapamycin , orally active , Microtubule/Tubulin , MKC-1 , Akt , pancreatic cancer , Inhibitor , MKC1	Akt , Microtubule Associated , Apoptosis , mTOR
	MKC-1 is an orally bioavailable, small-molecule, bisindolylmaleimide cell cycle inhibitor with potential antineoplastic ...		Akt , Microtubule Associated , Apoptosis , mTOR
T5429	Theaflavin 3,3'-digallate	8-Gingerol , TFDG	HIV Protease , Virus Protease , Antioxidant , HSV
	8-Gingerol (TFDG), a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory ...		HIV Protease , Virus Protease , Antioxidant , HSV
T61680	AKT-IN-5
	AKT-IN-5 (Example 8) is a Akt inhibitor with IC 50 values of 450 nM and 400 nM for Akt1 and Akt2, respectively [1].
T61756	APN/AKT-IN-1
	APN/AKT-IN-1 is a potent and dual inhibitor of APN and AKT with IC 50 s of 0.21 and 0.27 μM, respectively. APN/AKT-IN-1 ...