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Results for "

t 1

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  • Inhibitor Products
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    TargetMol | composition
Geranylgeranyl pyrophosphate, t-BA (1:1.5)
T40781L In house
(2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl dihydrogen diphosphate,tetrabutylammonium(1:1.5) is a common precursor of taxadiene such as Paclitaxel.
  • $195
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Geranylgeranyl pyrophosphate, t-BA (1:2)
T40781L1 In house
Geranylgeranyl pyrophosphate tetrabutylammonium(1:2) is one of the endogenous cholesterol and intermediates produced by the mevalerate pathway. Geranylgeranyl pyrophosphate tetrabutylammonium(1:2) is the common precursor of diterpenoids, for example, Paclitaxel. It can be used for cancer research.
  • $195
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T-1-MCPAB
T81054
T-1-MCPAB, a VEGFR-2 inhibitor with an IC50 of 0.135 µM, effectively suppresses MCF7 cell migration and has applications in cancer research [1].
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1-(t-Boc-Aminooxy)-3-aminooxy-propane
T139981352546-80-5
1-(t-Boc-Aminooxy)-3-aminooxy-propane is an alkyl/ether-based PROTAC linker utilized in the synthesis of PROTACs[1].
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1,4-Anhydro-2-de oxy-3-O-(t-butyldiphenylsilyl-D-erythro-pent-1-enitol
TNU1443130277-32-6
1,4-Anhydro-2-de oxy-3-O-(t-butyldiphenylsilyl-D-erythro-pent-1-enitol is a useful organic compound for research related to life sciences. The catalog number is TNU1443 and the CAS number is 130277-32-6.
  • Inquiry Price
7-10 days
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1,4-Anhydro-2-deoxy-3,5-bis-O-(t-butyl diphenylsilyl-D-erythro-pent-1-enitol
TNU1642105930-84-5
1,4-Anhydro-2-deoxy-3,5-bis-O-(t-butyl diphenylsilyl-D-erythro-pent-1-enitol is a useful organic compound for research related to life sciences. The catalog number is TNU1642 and the CAS number is 105930-84-5.
  • Inquiry Price
7-10 days
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T3Inh-1
T972050440-30-7
T3Inh-1 is an effective and selective inhibitor of ppGalNAc-T3 with an IC50 of 7 µM. T3Inh-1 prevents breast cancer cells. T3Inh-1 reduces FGF23 hormone levels in both tissue cells and mice, without causing any toxic side effects.
  • $115
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RH-5849
T19822112225-87-3
RH-5849 (1,2-Dibenzoyl-1-Tert-Butylhydrazine) is a novel Insect growth regulator that can be used as a potential insecticide to control olive fruit fly.
  • $56
In Stock
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Compound 1T-0216
T9544383147-88-4
Compound 1T-0216 is a blocker of AKT1-FAK interactions and reduces stimulation of FAK phosphorylation by extracellular stress in human SW620 colon cancer cells without affecting basal FAK phosphorylation.
  • $148
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N-Desethyl Chloroquine Hydrochloride
T11001L115912-96-6
N-Desethyl Chloroquine Hydrochloride ((±)-Desethylchloroquine 2HCl) is a desethylchloroquine derivative. desethylchloroquine competitively inhibits cyp2d1 /6-mediated reactions in vitro and in vivo.
  • $195
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NPS ALX Compound 4a hydrochloride(1:1)
T12262L1 In house
NPS ALX Compound 4a hydrochloride(1:1) is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist, with an IC50 of 7.2 nM and a Ki of 0.2 nM.
  • $84
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Compound 1T-0219 (SC)
T9545383147-92-0
Compound 1T-0219 (SC) is a blocker of AKT1-FAK interaction reducing the stimulation of FAK phosphorylation in response to extracellular pressure in human SW620 colon cancer cells without affecting basal FAK phosphorylation.
  • $148
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Ganoderic acid T1
T75632
Ganoderic acid T1, a deacetylated derivative of Ganoderic acid T, diminishes mitochondrial membrane potential and triggers cell apoptosis by activating caspase-9 and caspase-3, thus impairing the antioxidant defense system of cancer cells. Additionally, it elevates intracellular ROS levels, yielding pro-oxidant activities and cytotoxicity [1].
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Peptide T amide
TP2401113021-67-3
Peptide T amide is an octapeptide segment of HIV envelope gp120 and is used in AIDS therapy.
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L-(+)-Ampicillin
T0814L119379-33-0
L-(+)-Ampicillin is an isomer of Ampicillin. Ampicillin is a β-lactam antibiotic used for treating bacterial infections.
  • $1,520
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Ribonuclease T1
T736099026-12-4
Ribonuclease T1 (Rnase T1), widely utilized in biochemical research, is an endonuclease targeting single-stranded RNA. It cleaves the phosphodiester bond between 3'-guanosine residues and adjacent nucleoside 5'-OH groups, thereby producing 3'-GMP terminal oligonucleotides, and forms nucleoside 2', 3'-cyclic phosphoric acid intermediates in the process [1].
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Adenosine A1 receptor activator T62
T1412740312-34-3
Adenosine A1 receptor activator T62 is an allosteric enhancer of adenosine A1 receptor, and it produces antinociception in animal models of acute pain and also reduces hypersensitivity in models of inflammatory and nerve-injury pain[1][2][3].
  • $148
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CDK9-Cyclin T1 PPI-IN-1
T82758
CDK9-Cyclin T1 PPI-IN-1 (Compound B19) is a selective inhibitor of the CDK9-Cyclin T1 protein-protein interaction (PPI), suppressing cell proliferation in TNBC MDA-MB-231 cells with an IC50 of 0.044 μM and inducing apoptosis. This compound diminishes CDK9 transcriptional activity and downregulates phosphorylation of RNA Pol II CTD ser2. In vivo, CDK9-Cyclin T1 PPI-IN-1 effectively impedes tumor growth in a TNBC 4T1 mouse model [1].
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T-00127_HEV1
T16967900874-91-1
T-00127_HEV1 is an inhibitor of phosphatidylinositol 4-kinase III beta (IC50: 60 nM).
  • $51
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Ketomycin
T2557423364-22-9
Ketomycin is an antibiotic agent. It is formed from shikimic acid via chorismic acid and prephenic acid.
  • $1,520
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Josiphos SL-J009-1 Pd G3
T67259
Josiphos SL-J009-1 Pd G3 has a wide range of applications in life science related research.
    7-10 days
    Inquiry
    Josamycin HCl
    T7148L111033-19-5
    Josamycin HCl is a macrolide antibiotic.
    • $1,520
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    IT1t dihydrochloride
    T11693L1092776-63-0
    IT1t dihydrochloride inhibits CXCL12/CXCR4 interaction with IC50 of 2.1 nM. IT1t dihydrochloride is an antagonist of CXCR4.
    • $35
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    T3SS-IN-1
    T78930
    T3SS-IN-1 (compound B9) is a potent type III secretion system (T3SS) inhibitor that also suppresses hpa1 promoter activity and harpin protein expression, without impacting bacterial growth [1].
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    1,4-Anhydro-2,3-O-isopropylidene-5-O-t-butyldiphenylsilyl-4-thio-D-ribitol
    TNU15751320269-77-9
    1,4-Anhydro-2,3-O-isopropylidene-5-O-t-butyldiphenylsilyl-4-thio-D-ribitol is a Carbohydrate Derivative.
    • Inquiry Price
    7-10 days
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    2’,3’-Bis-O-(t-butyldimethylsilyl)-N1-methylpseudouridine
    TNU1576
    2’,3’-Bis-O-(t-butyldimethylsilyl)-N1-methylpseudouridine is a useful organic compound for research related to life sciences and the catalog number is TNU1576.
    • Inquiry Price
    7-10 days
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    RORγt/DHODH-IN-1
    T641452764662-15-7
    RORγt/DHODH-IN-1 (compound (R)-14d) is a potent, orally active dual inhibitor of RORγt (IC50: 0.083 μM) and DHODH (IC50: 0.172 μM), which exhibits significant in vivo anti-inflammatory effects.
    • $1,520
    10-14 weeks
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    5-Bromo-N1-t-butoxycarbonylmethyl-uracil
    TNU1453476667-21-7
    5-Bromo-N1-t-butoxycarbonylmethyl-uracil is a PNA-related Derivative.
    • Inquiry Price
    7-10 days
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    t-BuXPhos Pd G4
    T67242
    Methanesulfonato(2-di-t-butylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)(2'-methylamino-1,1'-biphenyl-2-yl)palladium(II) dichloromethane adduct is a useful organic compound for research related to life sciences and the catalog number is T67242.
      7-10 days
      Inquiry
      P(t-Bu)3 Pd G4
      T67261
      Methanesulfonato(tri-t-butylphosphino)(2'-methylamino-1,1'-biphenyl-2-yl)palladium(II) is a useful organic compound for research related to life sciences and the catalog number is T67261.
        7-10 days
        Inquiry
        APhos Pd G3
        T64791
        APhos Pd G3 has a wide range of applications in life science related research.
          7-10 days
          Inquiry
          4Me t-BuXPhos Pd G3
          T67252
          Methanesulfonato(2-di-t-butylphosphino-3,4,5,6-tetramethyl-2',4',6'-tri-i-propylbiphenyl)(2'-amino-1,1'-biphenyl-2-yl)palladium(II) is a useful organic compound for research related to life sciences and the catalog number is T67252.
            7-10 days
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            Promethazine hibenzate
            T0445L196590-75-9
            Promethazine is a neuroleptic medication and first-generation antihistamine of the phenothiazine family.
            • $1,520
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            t-BuXPhos Pd G3
            T66570
            Methanesulfonato(2-di-t-butylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl)palladium(II) is a useful organic compound for research related to life sciences and the catalog number is T66570.
              7-10 days
              Inquiry
              STD1T
              T36970893075-58-6
              STD1T is a selective and potent inhibitor of the deubiquitinase USP2a with potential anticancer activity that reduces cell cycle protein D1 protein levels in HCT116 colon and MCF-7 breast cancer cells.
              • $225
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              N1-Methyl-N3-[(2S)-2-(t-butoxycarbonyl)amino-3-(t-butoxycarbonyl)] propylpseudouridine
              TNU00781613530-24-7
              N1-Methyl-N3-[(2S)-2-(t-butoxycarbonyl)amino-3-(t-butoxycarbonyl)] propylpseudouridine is a Nucleoside Derivative - C-nucleoside; N-Alkylated nucleoside.
              • Inquiry Price
              7-10 days
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              Methanesulfonato[2-(di-t-butylphosphino)-2'-(N,N-dimethylamino)-1,1'-biphenyl](2'-amino-1,1'-biphenyl-2-yl)palladium(II)
              T672561445085-92-6
              Methanesulfonato[2-(di-t-butylphosphino)-2'-(N,N-dimethylamino)-1,1'-biphenyl](2'-amino-1,1'-biphenyl-2-yl)palladium(II) is a useful organic compound for research related to life sciences and the catalog number is T67256.
                7-10 days
                Inquiry
                UBE2T/FANCL-IN-1
                T387651359415-02-3
                UBE2T/FANCL-IN-1 is a highly effective inhibitor of UBE2T/FANCL-mediated FANCD2 monoubiquitylation. It greatly enhances the sensitivity of cells to Carboplatin, a DNA cross-linking agent.
                  7-10 days
                  Inquiry
                  T01-1
                  T735342356229-14-4
                  T01-1, a derivative of camptothecin, is an anticancer agent demonstrating significant anti-proliferative activity.
                  • $688
                  10-14 weeks
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                  Octreotide HCl
                  T2584L11607842-55-6
                  Octreotide HCl is a potent, long-acting synthetic SOMATOSTATIN octapeptide analog that inhibits the secretion of growth hormone.
                  • Inquiry Price
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                  Alprenolol hydrochloride, (S)-
                  T4560L115132-12-4
                  Alprenolol hydrochloride, (S)- is a nonselective β-blocker. It is also a serotonin 5HT1A receptor antagonist.
                  • $1,520
                  6-8 weeks
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                  RORγt inhibitor 1
                  T390381561770-72-6
                  RORγt inhibitor 1 is a RORγt allosteric inhibitor with an IC 50 value of 1 nM.
                  • $970
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                  physalin F
                  T871657423-71-9
                  Physalin F is a natural blocker of CaV2.3 (R-type) and CaV2.2 (N-type) voltage-gated calcium channels.It is a secosteroid with potent anti-inflammatory and immunomodulatory activities. Physalin F induces apoptosis of PBMC, decreasing the spontaneous proliferation and cytokine production caused by Human T-lymphotropic virus type 1 (HTLV-1) infection
                  • $45
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                  PD-1/PD-L1-IN-10
                  T96162487550-41-2
                  PD-1 PD-L1-IN-10 is an orally active PD-1 PD-L1 inhibitor (IC50 of 2.7 nM) with potent anticancer efficacy.
                  • $44
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                  Cbl-b-IN-3
                  T637902573775-59-2In house
                  Cbl-b-IN-3 is a potent proto-oncogene-B (CPL-B) inhibitor of casitas B-series lymphoma (ic50 < 1 nM). Cpl-b, a cyclic E3 ubiquitin protein ligase, is involved in the setting of T lymphocyte activation thresholds. Cpl-b negatively regulates p85 in an independent proteolytic manner, and participates in the recruitment of p85 to CD28 and T cell antigen receptor ζ through its E3 ubiquitin ligase activity. Inhibition of PI3K inhibits the enhancement of Cblb- -T cell activation.
                  • $383
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                  Crassicauline A
                  T3S189279592-91-9
                  1. Crassicauline A (Crassicauline I) and Yunaconitine possesses feeding deterrent activity against T. castaneum adults, with EC(5) values of 1134.5 and 653.4 ppm, respectively.
                  • $50
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                  T-0509
                  T2889596843-99-1In house
                  T-0509 is a selective beta 1 receptor agonist that increases inotropy in canine ventricular muscle and selectively down-regulates rat cardiac beta 1-adrenoceptors.
                  • $350
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                  OR015002
                  TD1004121-87-9
                  OR015002 shows toxicity to T. pyriformis with log(IGC50^-1) of 0.75.
                    Inquiry
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                    Peptide T acetate(106362-32-7 free base)
                    TP1785L
                    Peptide T acetate is an octapeptide from the V2 region of HIV-1 gp120. Peptide T is a synthetic octapeptide whose possible mechanism of action is the competitive inhibition of gp120 to the CD4 receptor as well as binding to vasointestinal peptide receptors and inhibiting cytokine action
                    • $97
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                    NY-BR-1 p904 A2 acetate(347142-73-8 free base)
                    TP1549L
                    T-cell clones specific for this NY-BR-1 p904 A2 acetate(347142-73-8 free base) can recognize breast tumor cells expressing NY-BR-1.
                    • $93
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