T12682 |
Emzadirib
|
2301085-04-9
|
99.79%
|
|
Emzadirib (RAD51-IN-2) is a potent RAD51 inhibitor with potential anticancer activity for the study of DNA damage repair.
|
T22319 |
DTP3
|
1809784-29-9
|
99.57%
|
|
DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.
|
T4187 |
Gemcitabine monophosphate sodium salt hydrate
|
1638288-31-9
|
|
|
Gemcitabine monophosphate disodium salt is a monophosphate derivative of Gemcitabine.
|
T3340 |
SCR7
|
1533426-72-0
|
|
|
SCR7, a specific DNA Ligase IV inhibitor, blocks nonhomologous end-joining (NHEJ).
|
T5539 |
GS-443902
|
1355149-45-9
|
|
|
GS-441524 was shown to be a safe and effective treatment for feline infectious peritonitis (FIP). The optimum dosage was found to be 4.0 mg/kg SC q24h for at lea...
|
TN4394 |
Kobophenol A
|
124027-58-3
|
98%
|
|
Kobophenol A has antimicrobial, and anti-inflammatory activities, it might be a candidate for treatment of inflammatory bone diseases relevant to osteoblast cell...
|
TN4938 |
Samidin
|
477-33-8
|
98%
|
|
Samidin has anti-inflammatory properties through suppression of NF-κB and AP-1-mediated-genes in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells.
|
T78046 |
RG7800 tetrahydrochloride
|
|
98%
|
|
RG7800 hydrochloride is an orally active modulator of SMN2 splicing, exhibiting EC50 values of 23 nM for SMN2 splicing and 87 nM for SMN protein production. This...
|
T78637 |
DdTTP trisodium
|
|
98%
|
|
Dideoxythymidine triphosphate trisodium (ddTTP), a 2',3'-dideoxyribonucleoside 5'-triphosphate (ddNTP), functions as a chain-elongation inhibitor of DNA polymera...
|
T78712 |
DNA Gyrase-IN-8
|
2925308-76-3
|
98%
|
|
DNA Gyrase-IN-8 is a potent inhibitor of DNA gyrase, demonstrating antimicrobial activity with an IC50 of 8.45 µM [1].
|
T78776 |
DNA gyrase B-IN-3
|
2412834-56-9
|
98%
|
|
DNA gyrase B-IN-3 (Compound A), with an IC50 of less than 10 nM, acts as an inhibitor of bacterial DNA gyrase B and exhibits antibacterial activity against Gram-...
|
T78814 |
COH1
|
20217-22-5
|
98%
|
|
COH1 is a ribonucleotide reductase (RR) inhibitor utilized in research pertaining to cancer, mitochondrial diseases, and neurodegenerative disorders [1].
|
T78866 |
DNA Gyrase-IN-9
|
|
98%
|
|
DNA Gyrase-IN-9 (compound 4j), an antibacterial agent, selectively targets DNA gyrase. It exhibits a minimum inhibitory concentration (MIC) of 0.5-2 µg/mL for Gr...
|
T78932 |
HDHODH-IN-12
|
|
98%
|
|
hDHODH-IN-12 is a potent inhibitor of dihydroorotate dehydrogenase (DHODH), exhibiting an inhibitory concentration (IC50) of 0.421 μM. As the rate-limiting enzym...
|
T78938 |
H3B-968
|
2912294-90-5
|
98%
|
|
H3B-968 is a potent inhibitor of Werner syndrome protein (WRN) with an IC50 of approximately 10 nM, effectively targeting its helicase, ATPase, and exonuclease a...
|
T79085 |
MC-VC-PAB-Cyclohexanediamine-Thailanstatin A
|
1609108-96-4
|
98%
|
|
MC-VC-PAB-Cyclohexanediamine-Thailanstatin A is a spliceostatin analog and a drug-linker conjugate for antibody-drug conjugates (ADC), comprising the cytotoxic c...
|
T79107 |
WRN inhibitor 1
|
2923008-44-8
|
98%
|
|
WRN Inhibitor 1 (example 7) is an inhibitor of the Werner Syndrome ATP-dependent helicase enzyme (WRN), selectively targeting its helicase domain. This compound ...
|
T79178 |
WRN inhibitor 2
|
2923009-56-5
|
98%
|
|
WRN Inhibitor 2 (example 118), a potent inhibitor of the WRN (Werner Syndrome ATP-dependent helicase enzyme), exhibits a pIC50 value of 7.0 or greater [1].
|
T79233 |
RdRP-IN-6
|
|
98%
|
|
RdRP-IN-6 (compound 27) is an inhibitor of RNA-dependent RNA polymerase (RdRp), exhibiting an IC90 value of 14.1 μM. It has potential applications in antiviral a...
|
T79290 |
SRE-II
|
|
98%
|
|
SRE-II, an amide derivative, serves as an activatable photosensitizer tailored for photodynamic cancer research, exhibiting diminished fluorescence and photosens...
|