T12682 |
RAD51-IN-2
|
2301085-04-9
|
98%
|
|
RAD51-IN-2 is a inhibitor of RAD51.
|
TN3806 |
Dehydroglyasperin C
|
199331-35-6
|
98%
|
|
Dehydroglyasperin C is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C possesses potent antioxidant, cancer chemop...
|
TN1664 |
Ganoderic acid H
|
98665-19-1
|
98%
|
|
Ganoderic acid H is a potent antitumour agent, it mediates its biological effects through the inhibition of transcription factors AP-1 and NF-kappaB, resulting i...
|
T5539 |
GS-443902
|
1355149-45-9
|
98%
|
|
GS-441524 was shown to be a safe and effective treatment for feline infectious peritonitis (FIP). The optimum dosage was found to be 4.0 mg/kg SC q24h for at lea...
|
TN1581 |
Dihydroguaiaretic acid
|
66322-34-7
|
98%
|
|
Dihydroguaiaretic acid has antioxidative activity, can significantly protect primary cultured neuronal cells against glutamate-induced oxidative stress.
|
TN4913 |
Riddelline
|
23246-96-0
|
98%
|
|
Riddelline is a potent genotoxic agent in vitro and induces significant elevations in unscheduled DNA synthesis and S-phase synthesis in rat liver.
|
T13479 |
2-Keto-D-galactose
|
54142-77-7
|
98%
|
|
2-Keto-D-galactose inhibits DNA synthesis and inhibits the proliferation of in vitro grown Ehrlich ascites tumor cells.
|
TN3802 |
Dehydrodiconiferyl alcohol
|
4263-87-0
|
98%
|
|
Dehydrodiconiferyl alcohol shows anti-adipogenic and anti-lipogenic effects in 3T3-L1 cells and primary mouse embryonic fibroblasts. Dehydrodiconiferyl alcohol c...
|
T40236 |
ART812
|
2607138-82-7
|
98%
|
|
ART812 is an orally active DNA polymerase Polθ inhibitor with an IC 50 value of 7.6 nM. ART812 has an IC 50 value of 240 nM for cell based microhomology-mediated...
|
T2627 |
Nolatrexed dihydrochloride
|
152946-68-4
|
98%
|
|
Nolatrexed Dihydrochloride is the dihydrochloride salt of nolatrexed, a water-soluble lipophilic quinazoline folate analog with antineoplastic activity. Nolatrex...
|
TN4938 |
Samidin
|
477-33-8
|
98%
|
|
Samidin has anti-inflammatory properties through suppression of NF-κB and AP-1-mediated-genes in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells.
|
T3340 |
SCR7
|
1533426-72-0
|
98%
|
|
SCR7, a specific DNA Ligase IV inhibitor, blocks nonhomologous end-joining (NHEJ).
|
TN4394 |
Kobophenol A
|
124027-58-3
|
98%
|
|
Kobophenol A has antimicrobial, and anti-inflammatory activities, it might be a candidate for treatment of inflammatory bone diseases relevant to osteoblast cell...
|
TMA0291 |
Dehydroglyasperin D
|
517885-72-2
|
98%
|
|
Dehydroglyasperin D exhibits anticancer, anti-inflammatory, anti-obesity, antioxidant and anti-aldose reductase effects, it inhibits the proliferation of HT-29 h...
|
TN1374 |
α-Chaconine
|
20562-03-2
|
98%
|
|
Alpha-Chaconine has anti-inflammatory effect, associated with the suppression of AP-1, and supports its possible therapeutic role for the treatment of sepsis. Al...
|
T17071 |
Thiarabine
|
26599-17-7
|
98%
|
|
Thiarabine displays effective anti-tumor activity. It also inhibition of DNA synthesis.
|
TQ0016 |
NKP-1339
|
197723-00-5
|
98%
|
|
NKP-1339 (IT-139) induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway.
|
T12935 |
SMN-C3
|
1449597-34-5
|
98%
|
|
SMN-C3 is an orally active modulator of SMN2 splicing, and has the potential to treat spinal muscular atrophy (SMA).
|
T33762 |
Fosifloxuridine nafalbenamide
|
1332837-31-6
|
98%
|
|
NUC-3373 is a bioactive chemical.
|
T16749 |
Rifalazil
|
129791-92-0
|
98%
|
|
Rifalazil is a rifamycin derivative, inhibits the bacterial DNA-dependent RNA polymerase and kills bacterial cells by blocking off the β-subunit in RNA polymeras...
|