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Parasite

Parasites include protozoans such as the agents of malaria, sleeping sickness, and amoebic dysentery; animals such as hookworms, lice, mosquitoes, and vampire bats; fungi such as honey fungus and the agents of ringworm; and plants such as mistletoe, dodder, and the broomrapes. There are six major parasitic strategies of exploitation of animal hosts, namely parasitic castration, directly transmitted parasitism (by contact), trophically transmitted parasitism (by being eaten), vector-transmitted parasitism, parasitoidism, and micropredation.
Cat No. product name
TP1313L Cecropin B acetate Cecropin B acetate 通过破坏 PXR/类视黄醇 X 受体 α (RXR-α) 复合物与 DNA 序列的结合来诱导 NF-κB 活化并抑制 CYP3A29。 Cecropin B acetate 具有很强的抗菌活性。
T27135 DDD85646 DDD85646 是 T. brucei N-myristoyltransferase 的抑制剂,Ki 为 1.44 nM,IC50 为 2 nM,EC50 为 2 nM。 hNMT 的 IC50 为 4 nM。
T16925 SQ109 SQ109 是一种有效的锥鞭毛体形式的寄生虫抑制剂 (IC50 = 50 nM)。 SQ109 是一种抗结核药物,靶向 MmpL3。
T16269 Nanaomycin A Nanaomycin A 是一种醌类抗生素,可重新激活人类癌细胞中沉默的肿瘤抑制基因。 Nanaomycin A 是 DNMT3B 的特异性抑制剂 (IC50 = 500 nM)。
TJO2742 DL-Methionine Methionine is an amino acid. Amino acids are the building blocks that our bodies use to make proteins. Methionine is found in meat, fish, and dairy products. It ...
T1177 Sulfaquinoxaline Sulfaquinoxaline is an antiprotozoal agent.
T2P2806 Hederacolchiside A1 Hederacolchiside A1 shows anti-leishmanial activity, it exhibits a strong antiproliferative activity on all stages of development of the parasite by altering mem...
T3718 Santonin α-santonin is a potent antiparasitic agent.
T7182 Metaflumizone Metaflumizone is a sodium channel blocker insecticide.
T13633 D-Phenothrin D-Phenothrin ((-)-trans-Phenothrin) is an orally active type II synthetic pyrethroid, which is widely used to kill insects, mosquitoes and human lice. D-phthalat...
T0194 Chloroquine phosphate Chloroquine is an aminoquinoline antimalarial and also is widely used as an autophagy inhibitor. Chloroquine also is an inhibitor of toll-like receptors (TLRs).
T1200 Phenothrin Phenothrin is a synthetic pyrethroid used to kill adult fleas and ticks.
T3524 Halofuginone hydrobromide Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of...
T5916 Fmoc-N-Me-Phe-OH Fmoc-N-Me-Phe-OH is a peptide inhibitor of Malaria Parasite
TN1860 Licoflavone B Licoflavone B has schistosomicidal activity, it showed high S. mansoni ATPase (IC50 of 23.78 μM) and ADPase (IC50 of 31.50 μM) inhibitory activities.
T1435 Praziquantel Praziquantel increases the permeability of the tegument of susceptible worms, resulting in an influx and increase in intra-tegumental calcium leading to rapid co...
T1556 Ornidazole Ornidazole is a nitroimidazole antiprotozoal agent used in ameba and trichomonas infections. It is partially plasma-bound and also has radiation-sensitizing acti...
T38400 Triclabendazole sulfoxide Triclabendazole sulfoxide is a main plasma metabolite of Triclabendazole. Triclabendazole sulfoxide inhibits membrane transporter ABCG2/BCRP and exhibits anti-pa...
T7459 Abametapir Abametapir, a metalloproteinase inhibitor, is able to target metalloproteinases critical to egg hatching and louse development.
T8146 Imidocarb dipropionate Imidocarb dipropionate is an antigenic insecticide, is active against the protozoan parasite B. bovis (IC50 : 0.87 µg/ml).
T0942 Quinacrine dihydrochloride Quinacrine Hydrochloride is the dihydrochloride salt of the 9-aminoacridine derivative quinacrine with potential antineoplastic and antiparasitic activities.
T8337 Nequinate Nequinate is an anticoccidial agent, preventing coccidiosis .
T5421 KDU691 KDU691 is a PI4K inhibitor.
T6856 Halofuginone Halofuginone, the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in the mamm...
T6532 Hesperadin Hesperadin(IC50=250 nM) effectively inhibits Aurora B. It potently reduces the activity of AMPK, MAPKAP-K1, MKK1, Lck, CHK1 and PHK, but it could not inhibit MKK...
T23132 Pentamidine dihydrochloride Pentamidine Dihydrochloride is an antimicrobial agent.
T6309 AZ960 AZ 960 is an effective ATP competitive JAK2 inhibitor (IC50/Ki: <3 nM and0.45 nM).
T0858 Flufenamic acid Flufenamic acid is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorder...
T2851 Daphnetin Daphnetin, a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM), and PKC (IC50: 25.01 μM), ...
T14324 Artemisone Artemisone is a potent and semi-synthetic antimalarial, inhibits P. falciparum strains (IC50: 0.83 nM). It also is a potent inhibitor of human CMV.
T0006 Methylene Blue trihydrate Methylene blue is a compound consisting of dark green crystals or crystalline powder, having a bronze-like luster. Solutions in water or alcohol have a deep blue...
T1152 Albendazole Albendazole is used as a drug indicated for the treatment of a variety of worm infestations.
T5420 Cycloguanil hydrochloride Cycloguanil is an active metabolite of the antimalarial compound proguanil. It acts as an inhibitor of dihydrofolate reductase (Kis: 0.3 and 1.5 nM for Plasmodiu...
TJO2691 (-)-Fucose 1. Anti-infective, anti-cancer, enhance immunity 2. Skin moisturizing and delaying skin aging 3. Nutritional supplement
TN1100 Nepodin Nepodin has antimalarial, and anti-inflammatory activities, it shows significant cyclooxygenase (COX) inhibitory activity. Nepodin has an antidiabetic effect, wh...
TN4670 Norlichexanthone Norlichexanthone has the potential to treat and/or prevent lifestyle-related diseases, including metabolic syndrome, type 2 diabetes, atherosclerosis and cardiov...
T1142 Clindamycin phosphate Clindamycin Phosphate is the phosphate salt form of clindamycin, a semi-synthetic, chlorinated broad-spectrum antibiotic produced by chemical modification of lin...
T5768 Bruceine B Bruceine B, a potent inhibitor of leukocyte-endothelial cell adhesion, may have anti-inflammatory activity, it can inhibit neutrophil adhesion to lipopolysacchar...
T23133 Pentamidine Pentamidine is an antifungal and antiprotozoal agent, interacting directly with the pathogen genome by binding to AT-rich regions of duplex DNA and the minor gro...
T4982 Benznidazol Benznidazole has an antiprotozoal activity by interfering with parasite protein biosynthesis, influencing cytokines production and stimulating host phagocytosis....
T0955 Oxyclozanide Oxyclozanide is a salicylanilide anthelmintic used in grazing animals for fasciola and cestode infestations.
T38272 Thiacloprid Thiacloprid is a neonicotinoid insecticide that acts as a selective agonist at insect nicotinic acetylcholine receptors (nAChRs) with IC50values of 2.7 and 860 n...
T1104 Paromomycin Sulfate Paromomycin binds specifically to the RNA oligonucleotide at the A site of bacterial 30S ribosomes, thereby causing misreading and premature termination of trans...
T8381 Amodiaquine Amodiaquine is a synthetic aminoquinoline, used to treat malaria.
T2S2172 Nerolidol 1. Nerolidol shows sedative effects in animals, oxidative process plays a crucial role on neuronal pathological consequence. 2. Nerolidol is mainly related to RO...
T1332 Permethrin Permethrin is a pyrethroid insecticide commonly used in the treatment of LICE INFESTATIONS and SCABIES.
T0607 Dihydroartemisinin Dihydroartemisinin is a metabolite of artemisinin.
T4059 Selamectin Selamectin is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. I...
T0951 Hydroxychloroquine sulfate Hydroxychloroquine sulfate inhibits plasmodial heme polymerase. It is a chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydrox...
T1632 Amitraz AMITRAZ is a white monoclinic crystals. Melting point 187-189°F (86-87°C). Insoluble in water. Used as an acaricide, insecticide and treatment of demodectic mang...
Cecropin B acetate
TP1313L
Cecropin B acetate 通过破坏 PXR/类视黄醇 X 受体 α (RXR-α) 复合物与 DNA 序列的结合来诱导 NF-κB 活化并抑制 CYP3A29。 Cecropin B acet...
DDD85646
T27135
DDD85646 是 T. brucei N-myristoyltransferase 的抑制剂,Ki 为 1.44 nM,IC50 为 2 nM,EC50 为 2 nM。 hNMT 的 IC50 为 4 nM。
SQ109
T16925
SQ109 是一种有效的锥鞭毛体形式的寄生虫抑制剂 (IC50 = 50 nM)。 SQ109 是一种抗结核药物,靶向 MmpL3。
Nanaomycin A
T16269
Nanaomycin A 是一种醌类抗生素,可重新激活人类癌细胞中沉默的肿瘤抑制基因。 Nanaomycin A 是 DNMT3B 的特异性抑制剂 (IC50 = 500...
DL-Methionine
TJO2742
Methionine is an amino acid. Amino acids are the building blocks that our bodies use to make proteins. Methionine is found in meat, fish, and dairy products. It ...
Sulfaquinoxaline
T1177
Sulfaquinoxaline is an antiprotozoal agent.
Hederacolchiside A1
T2P2806
Hederacolchiside A1 shows anti-leishmanial activity, it exhibits a strong antiproliferative activity on all stages of development of the parasite by altering mem...
Santonin
T3718
α-santonin is a potent antiparasitic agent.
Metaflumizone
T7182
Metaflumizone is a sodium channel blocker insecticide.
D-Phenothrin
T13633
D-Phenothrin ((-)-trans-Phenothrin) is an orally active type II synthetic pyrethroid, which is widely used to kill insects, mosquitoes and human lice. D-phthalat...
Chloroquine phosphate
T0194
Chloroquine is an aminoquinoline antimalarial and also is widely used as an autophagy inhibitor. Chloroquine also is an inhibitor of toll-like receptors (TLRs).
Phenothrin
T1200
Phenothrin is a synthetic pyrethroid used to kill adult fleas and ticks.
Halofuginone hydrobromide
T3524
Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of...
Fmoc-N-Me-Phe-OH
T5916
Fmoc-N-Me-Phe-OH is a peptide inhibitor of Malaria Parasite
Licoflavone B
TN1860
Licoflavone B has schistosomicidal activity, it showed high S. mansoni ATPase (IC50 of 23.78 μM) and ADPase (IC50 of 31.50 μM) inhibitory activities.
Praziquantel
T1435
Praziquantel increases the permeability of the tegument of susceptible worms, resulting in an influx and increase in intra-tegumental calcium leading to rapid co...
Ornidazole
T1556
Ornidazole is a nitroimidazole antiprotozoal agent used in ameba and trichomonas infections. It is partially plasma-bound and also has radiation-sensitizing acti...
Triclabendazole sulfoxide
T38400
Triclabendazole sulfoxide is a main plasma metabolite of Triclabendazole. Triclabendazole sulfoxide inhibits membrane transporter ABCG2/BCRP and exhibits anti-pa...
Abametapir
T7459
Abametapir, a metalloproteinase inhibitor, is able to target metalloproteinases critical to egg hatching and louse development.
Imidocarb dipropionate
T8146
Imidocarb dipropionate is an antigenic insecticide, is active against the protozoan parasite B. bovis (IC50 : 0.87 µg/ml).
Quinacrine dihydrochloride
T0942
Quinacrine Hydrochloride is the dihydrochloride salt of the 9-aminoacridine derivative quinacrine with potential antineoplastic and antiparasitic activities.
Nequinate
T8337
Nequinate is an anticoccidial agent, preventing coccidiosis .
KDU691
T5421
KDU691 is a PI4K inhibitor.
Halofuginone
T6856
Halofuginone, the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in the...
Hesperadin
T6532
Hesperadin(IC50=250 nM) effectively inhibits Aurora B. It potently reduces the activity of AMPK, MAPKAP-K1, MKK1, Lck, CHK1 and PHK, but it could not inhibit MKK...
Pentamidine dihydrochloride
T23132
Pentamidine Dihydrochloride is an antimicrobial agent.
AZ960
T6309
AZ 960 is an effective ATP competitive JAK2 inhibitor (IC50/Ki: <3 nM and0.45 nM).
Flufenamic acid
T0858
Flufenamic acid is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorder...
Daphnetin
T2851
Daphnetin, a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM), and PKC (IC50: 25.01 μM...
Artemisone
T14324
Artemisone is a potent and semi-synthetic antimalarial, inhibits P. falciparum strains (IC50: 0.83 nM). It also is a potent inhibitor of human CMV.
Methylene Blue trihydrate
T0006
Methylene blue is a compound consisting of dark green crystals or crystalline powder, having a bronze-like luster. Solutions in water or alcohol have a deep blue...
Albendazole
T1152
Albendazole is used as a drug indicated for the treatment of a variety of worm infestations.
Cycloguanil hydrochloride
T5420
Cycloguanil is an active metabolite of the antimalarial compound proguanil. It acts as an inhibitor of dihydrofolate reductase (Kis: 0.3 and 1.5 nM for Plasmodiu...
(-)-Fucose
TJO2691
1. Anti-infective, anti-cancer, enhance immunity 2. Skin moisturizing and delaying skin aging 3. Nutritional supplement
Nepodin
TN1100
Nepodin has antimalarial, and anti-inflammatory activities, it shows significant cyclooxygenase (COX) inhibitory activity. Nepodin has an antidiabetic effect, wh...
Norlichexanthone
TN4670
Norlichexanthone has the potential to treat and/or prevent lifestyle-related diseases, including metabolic syndrome, type 2 diabetes, atherosclerosis and cardiov...
Clindamycin phosphate
T1142
Clindamycin Phosphate is the phosphate salt form of clindamycin, a semi-synthetic, chlorinated broad-spectrum antibiotic produced by chemical modification of lin...
bruceine B
T5768
Bruceine B, a potent inhibitor of leukocyte-endothelial cell adhesion, may have anti-inflammatory activity, it can inhibit neutrophil adhesion to lipopolysacchar...
Pentamidine
T23133
Pentamidine is an antifungal and antiprotozoal agent, interacting directly with the pathogen genome by binding to AT-rich regions of duplex DNA and the minor gro...
Benznidazol
T4982
Benznidazole has an antiprotozoal activity by interfering with parasite protein biosynthesis, influencing cytokines production and stimulating host phagocytosis....
Oxyclozanide
T0955
Oxyclozanide is a salicylanilide anthelmintic used in grazing animals for fasciola and cestode infestations.
Thiacloprid
T38272
Thiacloprid is a neonicotinoid insecticide that acts as a selective agonist at insect nicotinic acetylcholine receptors (nAChRs) with IC50values of 2.7 and 860 n...
Paromomycin Sulfate
T1104
Paromomycin binds specifically to the RNA oligonucleotide at the A site of bacterial 30S ribosomes, thereby causing misreading and premature termination of trans...
Amodiaquine
T8381
Amodiaquine is a synthetic aminoquinoline, used to treat malaria.
nerolidol
T2S2172
1. Nerolidol shows sedative effects in animals, oxidative process plays a crucial role on neuronal pathological consequence. 2. Nerolidol is mainly related to RO...
Permethrin
T1332
Permethrin is a pyrethroid insecticide commonly used in the treatment of LICE INFESTATIONS and SCABIES.
Dihydroartemisinin
T0607
Dihydroartemisinin is a metabolite of artemisinin.
Selamectin
T4059
Selamectin is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. I...
Hydroxychloroquine sulfate
T0951
Hydroxychloroquine sulfate inhibits plasmodial heme polymerase. It is a chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydrox...
Amitraz
T1632
AMITRAZ is a white monoclinic crystals. Melting point 187-189°F (86-87°C). Insoluble in water. Used as an acaricide, insecticide and treatment of demodectic ma...
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