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Alkaloids

Alkaloids are a class of naturally occurring organic compounds that mostly contain basic nitrogen atoms, produced by a large variety of organisms including bacteria, fungi, plants, and animals. Alkaloids have a wide range of pharmacological activities including antimalarial (e.g. quinine), antiasthma (e.g. ephedrine), anticancer (e.g. homoharringtonine), cholinomimetic (e.g. galantamine), vasodilatory (e.g. vincamine), antiarrhythmic (e.g. quinidine), analgesic (e.g. morphine), antibacterial (e.g. chelerythrine), and antihyperglycemic activities (e.g. piperine). Many have found use in traditional or modern medicine, or as starting points for drug discovery. Other alkaloids possess psychotropic (e.g. psilocin) and stimulant activities (e.g. cocaine, caffeine, nicotine, theobromine), and have been used in entheogenic rituals or as recreational drugs. Alkaloids can be toxic too (e.g. atropine, tubocurarine).

Cat No. product name
T0461 Berberine chloride Berberine hydrochloride is an alkaloid from Hydrastis canadensis L., Berberidaceae and also found in many other plants. It is relatively toxic to parenterally bu...
T5S0661 Koumine 1. Koumine can treat the diabetic neuropathy. 2. Koumine has antineoplastic effect, may be a future breast cancer chemotherapeutic agent. 3. Koumine has a signif...
T2974 Cyclovirobuxine D Cyclovirobuxin D is extracted from Buxus microphylla.
T2887 Trigonelline Trigonelline, an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.
T2142 Yohimbine hydrochloride Yohimbine hydrochloride is a plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of ERECTILE DY...
TWP2911 Thymidine 1. Thymidine overload due to Thymidine phosphorylase deficiency, and mitochondrial toxicity caused by antiviral Thymidine analogues.
T2935 2-Phenylethylamine Phenylethylamine functions as a monoaminergic neuromodulator and, to a lesser extent, a neurotransmitter in the human central nervous system.
T5765 Ranaconitine Ranaconitine is an important diterpenoid alkaloid from Aconitum sinomontanum Nakai,ranaconitine has cardiotoxicity.
T2S1720 Huperzine B 1. Huperzine-B is a efficient inhibitor of human brain AChE. 2. Huperzine-B can enhance ognitive and protect neuro, may be potentially new drug candidates for Al...
T8185 (+)-Viroallosecurinine (+)-Viroallosecurinine is a natural alkaloid with antibacterial activity. It exhibits a MIC of 0.48 μg/mL for Ps. Aeruginosa and Staph. aureus.
T2774 Lycorine hydrochloride Lycorine (hydrochloride) is VE-cadherin inhibitor,and has IC50 of 1.2μM in Hey1B cell.It is an HCV inhibitor with strong activity.
Fr16605 Lupinine Lupinine is an alkaloid capable of counteracting ethanol anesthesia. Lupinine is an AChE and BChE inhibitor and potential CD69 activator found in species of Lora...
T4S1881 Aconine 1. Aconine is the febrifuge. 2. Aconine possesses gastric anaesthetic props.
T4036 Solasodine Solasodine(Purapuridine) is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family. Solasodine showed selective cytotoxicity again...
T2972 Rutaecarpine Rutaecarpine is an inhibitor of COX-2 with IC50 of 0.28 μM.
T2920 Berbamine dihydrochloride Berbamine dihydrochloride, a natural compound derived from the Berberis amurensis plant, has been shown to exhibit antitumor activity in several Ys.
T2725 Scopolamine hydrobromide Scopolamine hydrobromide is an alkaloid from SOLANACEAE, especially DATURA and SCOPOLIA. Scopolamine and its quaternary derivatives act as antimuscarinics like A...
T4S1321 (+)-Magnoflorine chloride 1. Magnoflorine has anti-inflammatory activity, it can inhibit inflammations.
TC0022 Desoxypeganine Desoxypeganine is an inhibitor of cholinesterase. It acting preferentially on butyrylcholinesterase, and as a selective inhibitor of monoamine oxidase A but not ...
T8207 Evolitrine Evolitrine is a natural compound.
T0970 Racanisodamine Anisodamine is an anticholinergic and α1-adrenergic receptor antagonist used in the treatment of acute circulatory shock.
T0792 (-)-Sparteine sulfate pentahydrate Sparteine sulfate pentahydrate is a class 1a antiarrhythmic agent and a sodium channel blocker. It can chelate the bivalents calcium and magnesium.
T4S0797 Berberine 1. Berberine is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism. 2. Berberine may as a broad-spectrum anti-microbial medicine, a com...
T1334 Hydroquinidine Dihydroquinidine is an organic compound, used as an antiarrhythmic agent.
TN1192 16-Epivoacarpine 16-Epivoacarpine is a natural product from Gelsemium elegans.
T4S1869 12-Epinapelline 12- Epinapelline is a diterpene alkaloid which displays anaesthetic activity as toxic neurological agents. Similar to aconitine, its suggested that modulation of...
T1287 Synephrine Synephrine is sympathetic alpha-adrenergic agonist used as a vasoconstrictor in circulatory failure, asthma, nasal congestion, and glaucoma.
T5760 (-​)​-​Salutaridine SINOACUTINE is a natural product isolated from Stephania epigaea Lo.Sinoacutine has protective effects against hydrogen peroxide-induced cell injury.
T6677 Sophocarpine Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.
T2832 Isocorydine S-Isocorydine(+) and its derivatives have anticancer activities.
TN1855 Laurolitsine Laurolitsine is an alkaloid isolated from the leaves of Peumus boldus Molina.
T5S1952 9-Methoxycamptothecin 9-Methoxycamptothecin (MCPT) has antitumour activities through topoisomerase inhibition.
TN6603 (S)-N-Glycidylphthalimide S-(N)-Glycidylphthalimide is a phthalimide derivative used as an intermediate in the preparation of the antibiotic Linezolid.
T4S2063 Tetrahydrocoptisine 1. Tetrahydrocoptisine has effective effects in suppressing inflammation. 2. Tetrahydrocoptisine possesses a protective effect on LPS-induced ALI through inhibit...
T5810 TABERSONINE HYDROCHLORIDE TABERSONINE HYDROCHLORIDE is a natural product extracted from the bean of Voacanga africana, is a potent inhibitor against Aβ(1 42) aggregation and toxicity.
T7975 Rhodamine B Rhodamine B is used as a tracer dye in water to determine the rate and direction of flow and transport.
TN1078 Seneciphylline Seneciphylline, one of the hepatotoxic pyrolizidine alkaloids, has mutagenic activity in Drosophila and their transfer into rat milk.Seneciphylline can significa...
T5811 Scopolamine hydrochloride HYOSCINE HYDROCHLORIDE versus placebo in preventing motion sickness has been shown to be effective.
T3364 Veratramine Veratramine(NSC17821; NSC23880) is a potent signal transduction inhibitor for treating tumors.
T3786 Tomatine An antiproliferatve agent of breast adenocarcinoma cells.
T2S1792 Lycobetaine 1. Ungeremine is a potential biofungicide against Penicillium roqueforti and Aspergillus niger.2. Ungeremine have strong antibacterial activity against Flavobact...
T5S1889 Yunaconitine 1. Yunaconitine has anti-inflammatory and analgesic actions. 2. Yunaconitine was shown to have anti-thermic effect in pyrexial rats when administered orally at a...
T2921 Sinomenine hydrochloride Sinomenine hydrochloride is extracted from Sinomenium Acutum Rehderett Wilson.
T0186 Docetaxel trihydrate Docetaxel is an antineoplastic agent that has a unique mechanism of action as an inhibitor of cellular mitosis and that currently plays a central role in the the...
TN2460 12-Ethyl-9-hydroxycamptothecin 7-Ethyl-10-Hydroxy-Camptothecin is a natural product isolated from Camptotheca acuminata Decne
T4S0779 D-tetrahydropalmatine D-Tetrahydropalmatine is a organic cation transporter 1 (OCT1) inhibitor, it can obviously inhibit the uptake of monocrotaline (MCT) in MDCK-hOCT1 cells and isol...
T4116 S-Adenosyl-DL-Methionine S-ADENOSYL-L-METHIONINE (SAM) is a ubiquitous methyl donor involved in a wide variety of biological reactions, including those mediated by DNA and protein methyl...
T2986 Jatrorrhizine hydrochloride Jatrorrhizine hydrochloride is extracted from berberidis, radix.
T5543 TriacetonaMine Triacetonamine protects the activitis of superoxide dismutase(SOD) and creatine phos-phate kinase (CPK); it also inhibits CaCl2 induced agglomeration of thromocy...
T5720 Boldine Boldine is a natual product .Boldine displays anti-cancer, cytoprotective , anti-oxidant and anti-inflammatory activities.
Berberine chloride
T0461
Berberine hydrochloride is an alkaloid from Hydrastis canadensis L., Berberidaceae and also found in many other plants. It is relatively toxic to parenterally bu...
Koumine
T5S0661
1. Koumine can treat the diabetic neuropathy. 2. Koumine has antineoplastic effect, may be a future breast cancer chemotherapeutic agent. 3. Koumine has a signif...
Cyclovirobuxine D
T2974
Cyclovirobuxin D is extracted from Buxus microphylla.
Trigonelline
T2887
Trigonelline, an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.
Yohimbine hydrochloride
T2142
Yohimbine hydrochloride is a plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of ERECTILE DY...
Thymidine
TWP2911
1. Thymidine overload due to Thymidine phosphorylase deficiency, and mitochondrial toxicity caused by antiviral Thymidine analogues.
2-Phenylethylamine
T2935
Phenylethylamine functions as a monoaminergic neuromodulator and, to a lesser extent, a neurotransmitter in the human central nervous system.
ranaconitine
T5765
Ranaconitine is an important diterpenoid alkaloid from Aconitum sinomontanum Nakai,ranaconitine has cardiotoxicity.
Huperzine B
T2S1720
1. Huperzine-B is a efficient inhibitor of human brain AChE. 2. Huperzine-B can enhance ognitive and protect neuro, may be potentially new drug candidates for Al...
(+)-Viroallosecurinine
T8185
(+)-Viroallosecurinine is a natural alkaloid with antibacterial activity. It exhibits a MIC of 0.48 μg/mL for Ps. Aeruginosa and Staph. aureus.
Lycorine hydrochloride
T2774
Lycorine (hydrochloride) is VE-cadherin inhibitor,and has IC50 of 1.2μM in Hey1B cell.It is an HCV inhibitor with strong activity.
Lupinine
Fr16605
Lupinine is an alkaloid capable of counteracting ethanol anesthesia. Lupinine is an AChE and BChE inhibitor and potential CD69 activator found in species of Lora...
Aconine
T4S1881
1. Aconine is the febrifuge. 2. Aconine possesses gastric anaesthetic props.
Solasodine
T4036
Solasodine(Purapuridine) is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family. Solasodine showed selective cytotoxicity again...
Rutaecarpine
T2972
Rutaecarpine is an inhibitor of COX-2 with IC50 of 0.28 μM.
Berbamine dihydrochloride
T2920
Berbamine dihydrochloride, a natural compound derived from the Berberis amurensis plant, has been shown to exhibit antitumor activity in several Ys.
Scopolamine hydrobromide
T2725
Scopolamine hydrobromide is an alkaloid from SOLANACEAE, especially DATURA and SCOPOLIA. Scopolamine and its quaternary derivatives act as antimuscarinics like A...
(+)-Magnoflorine chloride
T4S1321
1. Magnoflorine has anti-inflammatory activity, it can inhibit inflammations.
Desoxypeganine
TC0022
Desoxypeganine is an inhibitor of cholinesterase. It acting preferentially on butyrylcholinesterase, and as a selective inhibitor of monoamine oxidase A but not ...
Evolitrine
T8207
Evolitrine is a natural compound.
Racanisodamine
T0970
Anisodamine is an anticholinergic and α1-adrenergic receptor antagonist used in the treatment of acute circulatory shock.
(-)-Sparteine sulfate pentahydrate
T0792
Sparteine sulfate pentahydrate is a class 1a antiarrhythmic agent and a sodium channel blocker. It can chelate the bivalents calcium and magnesium.
Berberine
T4S0797
1. Berberine is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism. 2. Berberine may as a broad-spectrum anti-microbial medicine, a com...
Hydroquinidine
T1334
Dihydroquinidine is an organic compound, used as an antiarrhythmic agent.
16-Epivoacarpine
TN1192
16-Epivoacarpine is a natural product from Gelsemium elegans.
12-Epinapelline
T4S1869
12- Epinapelline is a diterpene alkaloid which displays anaesthetic activity as toxic neurological agents. Similar to aconitine, its suggested that modulation of...
Synephrine
T1287
Synephrine is sympathetic alpha-adrenergic agonist used as a vasoconstrictor in circulatory failure, asthma, nasal congestion, and glaucoma.
(-​)​-​Salutaridine
T5760
SINOACUTINE is a natural product isolated from Stephania epigaea Lo.Sinoacutine has protective effects against hydrogen peroxide-induced cell injury.
Sophocarpine
T6677
Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.
Isocorydine
T2832
S-Isocorydine(+) and its derivatives have anticancer activities.
Laurolitsine
TN1855
Laurolitsine is an alkaloid isolated from the leaves of Peumus boldus Molina.
9-Methoxycamptothecin
T5S1952
9-Methoxycamptothecin (MCPT) has antitumour activities through topoisomerase inhibition.
(S)-N-Glycidylphthalimide
TN6603
S-(N)-Glycidylphthalimide is a phthalimide derivative used as an intermediate in the preparation of the antibiotic Linezolid.
Tetrahydrocoptisine
T4S2063
1. Tetrahydrocoptisine has effective effects in suppressing inflammation. 2. Tetrahydrocoptisine possesses a protective effect on LPS-induced ALI through inhibit...
TABERSONINE HYDROCHLORIDE
T5810
TABERSONINE HYDROCHLORIDE is a natural product extracted from the bean of Voacanga africana, is a potent inhibitor against Aβ(1 42) aggregation and toxicity.
Rhodamine B
T7975
Rhodamine B is used as a tracer dye in water to determine the rate and direction of flow and transport.
Seneciphylline
TN1078
Seneciphylline, one of the hepatotoxic pyrolizidine alkaloids, has mutagenic activity in Drosophila and their transfer into rat milk.Seneciphylline can significa...
Scopolamine hydrochloride
T5811
HYOSCINE HYDROCHLORIDE versus placebo in preventing motion sickness has been shown to be effective.
Veratramine
T3364
Veratramine(NSC17821; NSC23880) is a potent signal transduction inhibitor for treating tumors.
Tomatine
T3786
An antiproliferatve agent of breast adenocarcinoma cells.
Lycobetaine
T2S1792
1. Ungeremine is a potential biofungicide against Penicillium roqueforti and Aspergillus niger.2. Ungeremine have strong antibacterial activity against Flavobact...
Yunaconitine
T5S1889
1. Yunaconitine has anti-inflammatory and analgesic actions. 2. Yunaconitine was shown to have anti-thermic effect in pyrexial rats when administered orally at a...
Sinomenine hydrochloride
T2921
Sinomenine hydrochloride is extracted from Sinomenium Acutum Rehderett Wilson.
Docetaxel trihydrate
T0186
Docetaxel is an antineoplastic agent that has a unique mechanism of action as an inhibitor of cellular mitosis and that currently plays a central role in the the...
12-Ethyl-9-hydroxycamptothecin
TN2460
7-Ethyl-10-Hydroxy-Camptothecin is a natural product isolated from Camptotheca acuminata Decne
D-tetrahydropalmatine
T4S0779
D-Tetrahydropalmatine is a organic cation transporter 1 (OCT1) inhibitor, it can obviously inhibit the uptake of monocrotaline (MCT) in MDCK-hOCT1 cells and isol...
S-Adenosyl-DL-Methionine
T4116
S-ADENOSYL-L-METHIONINE (SAM) is a ubiquitous methyl donor involved in a wide variety of biological reactions, including those mediated by DNA and protein methyl...
Jatrorrhizine hydrochloride
T2986
Jatrorrhizine hydrochloride is extracted from berberidis, radix.
TriacetonaMine
T5543
Triacetonamine protects the activitis of superoxide dismutase(SOD) and creatine phos-phate kinase (CPK); it also inhibits CaCl2 induced agglomeration of thromocy...
Boldine
T5720
Boldine is a natual product .Boldine displays anti-cancer, cytoprotective , anti-oxidant and anti-inflammatory activities.