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Inhibitors Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling
MAPK Membrane transporter/Ion channel Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome Stem Cells Tyrosine Kinase/Adaptors Ubiquitination Others
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Search Result

Search Results for "pi3k"

Targets

PI3K

Libraries

PI3K-AKT-mTOR Compound Library Anti-Pancreatic Cancer Compound Library Cytokine Inhibitor Library HIF-1 Signaling Pathway Compound Library
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Compounds

Cat No. Product Name
T2377 Pilaralisib analogue XL147 analogue , SAR245408 DNA-PK , Apoptosis , PI3K
XL147 analogue is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/γ.
T11129L Duvelisib (R enantiomer) hydrochloride INK1197 R enantiomer HCl , Duvelisib (R enantiomer) hydrochloride(1261590-48-0 Free base) , IPI-145 R enantiomer HCl PI3K
Duvelisib (R enantiomer) hydrochloride is a PI3K inhibitor. Duvelisib (R enantiomer) hydrochloride is the less active en...
T2008 LY294002 NSC 697286 , SF 1101 , LY 294002 Casein Kinase , DNA-PK , Apoptosis , PI3K , Autophagy
LY294002 is an inhibitor of PI3K (IC50s: 0.5/0.57/0.97 μM for PI3Kα/δ/β in cell-free assays). It also blocks autophagoso...
T11052L Disitertide acetate Disitertide acetate(272105-42-7 Free base) , P144 acetate TGF-beta/Smad
Disitertide acetate is a peptidic transforming growth factor-beta 1 (TGF-β1) inhibitor specifically designed to block th...
T2235 Dactolisib NVP-BEZ235 , BEZ235 PI3K , ATM/ATR , Autophagy , mTOR
Dactolisib is an orally bioavailable inhibitor of PI3K and mTOR (IC50s: 4 nM/5 nM/7 nM/75 nM, and 20.7 nM for p110α/p110...
T3S0013 Ethyl trans-caffeate Ethyl caffeate , Caffeic Acid Ethyl Ester Others
1. Ethyl caffeate has anti-inflammatory activity. 2. Ethyl caffeate may as a promising natural compound for future appli...
T60196 IHMT-PI3Kδ-372 S-isomer PI3K
IHMT-PI3Kδ-372 S-isomer is a potent and selective PI3Kδ inhibitor with an IC50 of 14 nM. IHMT-PI3Kδ-372 S-isomer shows h...
T5831 Selective PI3Kδ Inhibitor 1 PI3K
Selective PI3Kδ Inhibitor 1 is a PI3Kδ Inhibitor( IC50 = 0.9 nM).
T28416 PIK-108 PIK108 , PIK 108 PI3K
PIK-108 is an allosteric inhibitor of phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunits β and δ (PI3Kβ/δ...
T2248 AS-605240 AS 605240 PI3K , Autophagy
AS-605240 is an effective and specific inhibitor of PI3Kγ (IC50/Ki: 87.8 nM).
T2746 Sophocarpine monohydrate Sophocarpine Apoptosis , Influenza Virus , Akt , PI3K , Autophagy , AMPK
Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.
TL0006 Cichoric Acid Chicoric Acid , Dicaffeoyltartaric acid Reactive Oxygen Species , HIV Protease
Chicoric Acid is a potent inhibitor of human immunodeficiency virus type-1 (HIV-1) integrase and the replication in tiss...
T2256 CNX-1351 PI3K
CNX-1351 is a potent and isoform-selective targeted covalent PI3Kα inhibitor.
T61966 PI3K-IN-26
PI3K-IN-26 is an effective PI3K inhibitor. PI3K-IN-26 inhibits the proliferation of SU-DHL-6 cells, IC50= 36 nM (WO20160...
T61618 PI3K-IN-38
PI3K-IN-38 (compound 123) is an orally active PI3K inhibitor with IC 50 of 0.541 μM (PI3K-α). PI3K-IN-38 shows activitie...
T61516 PI3K/mTOR Inhibitor-3
PI3K/mTOR Inhibitor-3 (compound 12), an imidazoline, is a potent PI3K and mTOR dual inhibitor. PI3K/mTOR Inhibitor-3 has...
T60564 PI3K/Akt/mTOR-IN-2
PI3K/Akt/mTOR-IN-2 is an inhibitor of PI3K/AKT/mTOR pathway. PI3K/Akt/mTOR-IN-2 can induce cancer cell cycle arrest and ...
T60769 COX-2/PI3K-IN-2
COX-2/PI3K-IN-2 (compound 5f) has properties of anti-inflammatory and anti-cancer. COX-2/PI3K-IN-2 is a selective inhibi...
T30989 CLR457 CLR 457 , CLR-457
CLR457 is an oral bioavailable phosphatidylinositol 3-kinase (PI3K) pan inhibitor with potential anti-tumor activity. CL...
T29615 ACP-319 ACP319
ACP-319 is an oral phosphatidylinositol 3-kinase (PI3K) inhibitor that can prevent the activation of PI3K/AKT (protein k...
Pilaralisib analogue
T2377
synonym: XL147 analogue , SAR245408
Target:
Duvelisib (R enantiomer) hydrochloride
T11129L
synonym: INK1197 R enantiomer HCl , Duvelisib (R enantiomer) hydrochloride(1261590-48-0 Free base) , IPI-145 R enantiomer HCl
Target:
LY294002
T2008
synonym: NSC 697286 , SF 1101 , LY 294002
Target:
Disitertide acetate
T11052L
synonym: Disitertide acetate(272105-42-7 Free base) , P144 acetate
Target:
Dactolisib
T2235
synonym: NVP-BEZ235 , BEZ235
Target:
Ethyl trans-caffeate
T3S0013
synonym: Ethyl caffeate , Caffeic Acid Ethyl Ester
Target:
IHMT-PI3Kδ-372 S-isomer
T60196
synonym:
Target:
Selective PI3Kδ Inhibitor 1
T5831
synonym:
Target:
PIK-108
T28416
synonym: PIK108 , PIK 108
Target:
AS-605240
T2248
synonym: AS 605240
Target:
Sophocarpine monohydrate
T2746
synonym: Sophocarpine
Target:
Cichoric Acid
TL0006
synonym: Chicoric Acid , Dicaffeoyltartaric acid
Target:
CNX-1351
T2256
synonym:
Target:
PI3K-IN-26
T61966
synonym:
Target:
PI3K-IN-38
T61618
synonym:
Target:
PI3K/mTOR Inhibitor-3
T61516
synonym:
Target:
PI3K/Akt/mTOR-IN-2
T60564
synonym:
Target:
COX-2/PI3K-IN-2
T60769
synonym:
Target:
CLR457
T30989
synonym: CLR 457 , CLR-457
Target:
ACP-319
T29615
synonym: ACP319
Target:
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