T12459 |
PI3K/mTOR Inhibitor-2
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mTOR
,
PI3K
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PI3K/mTOR Inhibitor-2 is a potent pan inhibitor of PI3K and mTOR with IC50s of 3.4, 34, 16,1 and 4.7 nM for PI3Kα, PI3Kβ... |
T1826 |
PI3K-IN-1
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XL765,SAR245409,Voxtalisib (SAR245409, XL765) Analogue,Voxtalisib Analogue |
PI3K
,
DNA-PK
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Voxtalisib (SAR245409, XL765)Analogue is a dual inhibitor of mTOR/PI3K, mostly for p110γ , also inhibits DNA-PK and mTOR... |
T61618 |
PI3K-IN-38
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PI3K
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PI3K-IN-38 is an orally available and potent PI3K inhibitor with an IC50 value of 0.541 µM for PI3K-α. PI3K-IN-38 exhibi... |
T60564 |
PI3K/Akt/mTOR-IN-2
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PI3K
,
mTOR
,
Akt
,
Apoptosis
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PI3K/Akt/mTOR-IN-2 is a potent PI3K/AKT/mTOR inhibitor.PI3K/Akt/mTOR-IN-2 has anticancer effects and is selective for MD... |
T24637 |
PI3K inhibitor C 96
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PI3K-IN-C96,PI3K IN C96 |
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PI3K inhibitor C 96 is an inhibitor of phosphatidylinositol 3-kinase. It shows effective activity against multiple myelo... |
T2265 |
Bimiralisib
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PQR309,PI3K-IN-2,5-(4,6-dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine |
S6 Kinase
,
PI3K
,
mTOR
,
Others
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PI3K-IN-2 is an orally bioavailable pan inhibitor of PI3K and inhibitor of the mTOR, with potential antineoplastic activ... |
T39581 |
PI3K-IN-19 hydrochloride
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PI3K-IN-19 hydrochloride (WO2017153220, step 5) acts as a phosphatidylinositol-3-kinase (PI3K) inhibitor. |
T12456 |
PI3K-IN-10
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PI3K
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PI3K-IN-10 is a potent inhibitor of pan-PI3K . |
T12457 |
PI3K-IN-6
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PI3K
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PI3K-IN-6 is an oral active and highly selective inhibitor of phosphoinositide 3-kinase (PI3K) β/δ(IC50 values of 7.8 nM... |
T12458 |
PI3K-IN-9
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PI3K
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PI3K-IN-9 is a potent and selective inhibitor of PI3Kδ(IC50 of 8.9 nM). |
T12455 |
PI3K/HDAC-IN-1
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PI3K
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PI3K/HDAC-IN-1 is a potent PI3K and HDAC dual inhibitor(IC50s of 8.1 nM and 1.4 nM, respectively). |
T12460 |
PI3K/mTOR Inhibitor-1
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PI3K
|
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PI3K/mTOR Inhibitor-1 is a potent, orally bioavailable dual inhibitor of PI3K/mTOR (PI3Kα/PI3Kβ/PI3Kδ/PI3Kγ/mTOR with IC... |
T36087 |
PI3K-IN-22
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T12365 |
PARP/PI3K-IN-1
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PI3K
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PARP/PI3K-IN-1 is a potent inhibitor of PARP/PI3K(pIC50 values of 8.22). |
T62392 |
PI3K-IN-34
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PI3K-IN-34 (Compound 6g) is a highly selective inhibitor of PI3K that acts on PI3K-α (IC50: 11.73 μM), PI3K-β (IC50: 6.0... |
T62779 |
PI3K-IN-35
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PI3K-IN-35 (Compound 6l) is a highly selective inhibitor of PI3K, acting on PI3K-α (IC50: 13.98 μM), PI3K-β (IC50: 7.22 ... |
T63957 |
PI3K-IN-29
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PI3K-IN-29 is a potent PI3K inhibitor. PI3K-IN-29 displays good inhibition potencies against U87MG, HeLa and HL60 cells ... |
T62580 |
PI3K-IN-37
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PI3K-IN-37 (Example 84.1) is an inhibitor of PI3K α (IC50: 6 nM), PI3K β (IC50: 8 nM) and PI3K δ (IC50: 4 nM). PI3K-IN-3... |
T73150 |
PI3K-IN-36
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PI3K-IN-36 is a potent PI3K inhibitor. PI3K-IN-36 can be used in research of follicular lymphoma (FL) . |
T63323 |
PI3K-IN-33
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PI3K-IN-33 is a highly selective PI3K inhibitor that acts on PI3K-α (IC50: 11.73 μM), PI3K-β (IC50: 6.09 μM) and PI3K-δ ... |