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Search Results for " pi3k "

377

Compounds

98

Natural Products

72

Recombinant Proteins

6

Libraries

Cat No. Product Name Synonyms Targets
T64392 PI3K-IN-46 PI3K
PI3K-IN-46 is a specific inhibitor of PI3Kγ.
T12459 PI3K/mTOR Inhibitor-2 PI3K , mTOR
PI3K/mTOR Inhibitor-2 is a potent pan inhibitor of PI3K and mTOR with IC50s of 3.4, 34, 16,1 and 4.7 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR. PI3K/mTOR Inhibitor-2 has antitumor activity.
T12365 PARP/PI3K-IN-1 PARP , PI3K
PARP/PI3K-IN-1 is a novel dual poly (ADP-ribose) polymerase (PARP) and phosphatidylinositol 3-kinase (PI3K) dual inhibitor with anticancer, antitumour and antiproliferative activities for the study of breast, pancreatic ...
T1826 PI3K-IN-1 Voxtalisib Analogue,Voxtalisib (SAR245409, XL765) Analogue,XL765,SAR245409 DNA-PK , PI3K
PI3K-IN-1 (Voxtalisib Analogue) is a dual inhibitor of mTOR/PI3K, mostly for p110γ , also inhibits DNA-PK and mTOR.
T61618 PI3K-IN-38 PI3K
PI3K-IN-38 is an orally available and potent PI3K inhibitor with an IC50 value of 0.541 µM for PI3K-α. PI3K-IN-38 exhibits anticancer and anti-inflammatory activity and inhibits tumor growth in vivo.
T39581 PI3K-IN-19 hydrochloride PI3K-IN-19 hydrochloride
PI3K-IN-19 hydrochloride (WO2017153220, step 5) acts as a phosphatidylinositol-3-kinase (PI3K) inhibitor.
T2265 Bimiralisib 5-(4,6-dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine,PQR309,PI3K-IN-2 Others , PI3K , S6 Kinase , mTOR
Bimiralisib (PI3K-IN-2) is an orally bioavailable pan inhibitor of PI3K and inhibitor of the mTOR, with potential antineoplastic activity. PI3K-IN-2 inhibits the PI3K kinase isoforms alpha, beta, gamma and delta and, to ...
T24637 PI3K inhibitor C 96 PI3K IN C96,PI3K-IN-C96
PI3K inhibitor C 96 is an inhibitor of phosphatidylinositol 3-kinase. It shows effective activity against multiple myeloma in vitro and in vivo.
T60564 PI3K/Akt/mTOR-IN-2 Apoptosis , Akt , PI3K , mTOR
PI3K/Akt/mTOR-IN-2 is a potent PI3K/AKT/mTOR inhibitor.PI3K/Akt/mTOR-IN-2 has anticancer effects and is selective for MDA-MB-231 cells with an IC50 of 2.29 μM.PI3K/Akt/mTOR-IN-2 exhibits anticancer activity and induces c...
T2078 Fimepinostat CUDC-907,PI3K/HDAC Inhibitor,CUDC 907 Apoptosis , PI3K , HDAC
Fimepinostat (CUDC 907) is an orally bioavailable inhibitor of both phosphoinositide 3-kinase (PI3K) class I and pan-histone deacetylase (HDAC) enzymes, with potential antineoplastic activity. Upon oral administration, C...
T36087 PI3K-IN-22 CAY10626
PI3K-IN-22 is a useful organic compound for research related to life sciences. The catalog number is T36087 and the CAS number is 1202884-94-3.
T12456 PI3K-IN-10 PI3K
PI3K-IN-10 is a potent inhibitor of pan-PI3K .
T12457 PI3K-IN-6 PI3K
PI3K-IN-6 is an oral active and highly selective inhibitor of phosphoinositide 3-kinase (PI3K) β/δ(IC50 values of 7.8 nM/5.3 nM , respectively).
T12458 PI3K-IN-9 PI3K
PI3K-IN-9 is a potent and selective inhibitor of PI3Kδ(IC50 of 8.9 nM).
T12455 PI3K/HDAC-IN-1 PI3K
PI3K/HDAC-IN-1 is a potent PI3K and HDAC dual inhibitor(IC50s of 8.1 nM and 1.4 nM, respectively).
T12460 PI3K/mTOR Inhibitor-1 PI3K
PI3K/mTOR Inhibitor-1 is a potent, orally bioavailable dual inhibitor of PI3K/mTOR (PI3Kα/PI3Kβ/PI3Kδ/PI3Kγ/mTOR with IC50s of 20/376/204/46/186 nM)
T71272 PI3K/Akt-IN-C89
PI3K/Akt-IN-C89 is a novel Inhibitor of the PI3K-Akt Pathway, Inducing Autophagy of Female Germline Stem Cells.
T62580 PI3K-IN-37
PI3K-IN-37 (Example 84.1) is an inhibitor of PI3K α (IC50: 6 nM), PI3K β (IC50: 8 nM) and PI3K δ (IC50: 4 nM). PI3K-IN-37 inhibits mTOR with an IC50 value of 4 nM.
T73150 PI3K-IN-36
PI3K-IN-36 is a potent PI3K inhibitor. PI3K-IN-36 can be used in research of follicular lymphoma (FL) .
T64052 PI3K-IN-27
PI3K-IN-27 is a potent inhibitor of PI3K, a large family of lipid signalling kinases that play a key role in cellular processes such as cell growth, differentiation, migration and apoptosis. PI3K-IN-27 has shown research...
T79701 PI3K-IN-48 Akt
PI3K-IN-48, a PI3K inhibitor, exhibits an IC50 of 1.55 ± 0.18 μM in A549 cells, demonstrating its potency in this context. It induces G0/G1 phase arrest and cell apoptosis, while also down-regulating the expression of p-...
T78853 PI3K-IN-47 PI3K
PI3K-IN-47 (Compound 27) is a potent bivalent inhibitor targeting the phosphoinositide 3-kinases (PI3K) family, exhibiting inhibitory concentration (IC50) values of 0.44 nM for PI3Kα, and 7.18 nM, 13.92 nM, 22.83 nM for ...
T62392 PI3K-IN-34
PI3K-IN-34 (Compound 6g) is a highly selective inhibitor of PI3K that acts on PI3K-α (IC50: 11.73 μM), PI3K-β (IC50: 6.09 μM) and PI3K-δ (IC50: 11.18 μM). PI3K-IN-34 can be used to study leukaemia.
T63323 PI3K-IN-33
PI3K-IN-33 is a highly selective PI3K inhibitor that acts on PI3K-α (IC50: 11.73 μM), PI3K-β (IC50: 6.09 μM) and PI3K-δ (IC50: 11.18 μM). PI3K-IN-33 is capable of blocking the cell cycle in G2/M phase and can induce apop...
T61966 PI3K-IN-26
PI3K-IN-26 is an effective PI3K inhibitor. PI3K-IN-26 inhibits the proliferation of SU-DHL-6 cells, IC50= 36 nM.
T79566 PI3K-IN-41 PI3K
PI3K-IN-41 (compound 2), a photocaged PI3K inhibitor (IC50=18.92 nM) with anticancer properties, demonstrates potent PI3K inhibition following UV light irradiation and has been shown to enhance antitumor effects [1]. Thi...
T62696 PI3K-IN-30
PI3K-IN-30 (compound 6d) is a potent inhibitor of PI3K, acting on PI3Kα (IC50: 5.1 nM), PI3Kβ (IC50: 136 nM), PI3Kγ (IC50: 30.7 nM) and PI3Kδ (IC50: 8.9 nM).
T63682 PI3K-IN-2
PI3K-IN-2 are orally active PI3Kβ/δ inhibitors with IC50 values of 7.1 nM, 8.6 nM, and higher selectivity than PI3Kσ (IC50: 13 nM) and PI3Kγ (IC50: 190 nM), respectively.
T64041 PI3K/mTOR Inhibitor-7
PI3K/mTOR Inhibitor-7 is a potent dual PI3K/mTOR inhibitor. PI3K/mTOR Inhibitor-7 is 4.7-fold more potent than gedatolisib, with IC50 values of 1.4 μM and 0.3 μM, respectively. 10 μM of PI3K/mTOR Inhibitor-7 is able to s...
T63470 PI3K/mTOR Inhibitor-8
PI3K/mTOR Inhibitor-8 is a dual inhibitor of PI3K (PI3Kα IC50: 0.46 nM) and mTOR (mTOR IC50: 12 nM). PI3K/mTOR Inhibitor-8 blocks the cell cycle of HCT-116 cells in G1/S phase and induces apoptosis. apoptosis).
T72408 PI3K/mTOR Inhibitor-5
PI3K/mTOR Inhibitor-5 is a potent and dual PI3K and mTOR inhibitor, with IC 50 values of 86.9 nM and 14.6 nM, respectively .
T62438 PI3K/mTOR Inhibitor-9
PI3K/mTOR Inhibitor-9 (Compound 1) is a potent inhibitor of both mTOR and PI3K, acting on mTOR (IC50: 38 nM), PI3Kα (IC50: 6.6 nM), PI3Kγ (IC50: 6.6 nM) and PI3Kδ (IC50: 0.8 nM).
T62779 PI3K-IN-35
PI3K-IN-35 (Compound 6l) is a highly selective inhibitor of PI3K, acting on PI3K-α (IC50: 13.98 μM), PI3K-β (IC50: 7.22 μM) and PI3K-δ (IC50: 10.94 μM). PI3K-IN-35 blocks the cell cycle in G2/M phase and induces apoptosi...
T63957 PI3K-IN-29
PI3K-IN-29 is a potent PI3K inhibitor. PI3K-IN-29 displays good inhibition potencies against U87MG, HeLa and HL60 cells with IC 50 values of 0.264, 2.04 and 1.14 µM, respectively. PI3K-IN-29 inhibits PI3K/Akt pathway by ...
T62470 PI3K-IN-31
PI3K-IN-31 (Compound 6b) is a potent inhibitor of PI3K that acts on PI3Kα (IC50: 3.7 nM), PI3Kβ (IC50: 74 nM), PI3Kγ (IC50: 14.6 nM) and PI3Kδ (IC50: 9.9 nM). PI3K-IN-31 has shown anticancer activity. PI3K-IN-31 showed a...
T73118 PI3K-IN-28
PI3K-IN-28 is a potent inhibitor of PI3K . PI3K-IN-28 displays the most potent activity with lower toxic effects on MCF-10a. PI3K-IN-28 displays half-maximal inhibitory concentration ( IC 50 , μM) values of 5.8, 2.3, an...
T62409 PI3K-IN-23
PI3K-IN-23 is a (E)-9-oxooctadec-10-en-12-ynoic acid analogue that promotes glucose uptake (EC50: 7.00 μM).
T78836 IHMT-PI3K-455 PI3K
IHMT-PI3K-455 (Compound 15u) is a potent, selective PI3Kγ/δ dual inhibitor, demonstrating oral activity, with IC50 values of 7.1 nM for PI3Kγ and 0.57 nM for PI3Kδ. This compound inhibits AKT phosphorylation and promotes...
T64219 PI3K/mTOR Inhibitor-6
PI3K/mTOR Inhibitor-6 (Compound 19c) is a potent dual PI3K/mTOR inhibitor that is more stable than gedatolisib in artificial gastric fluid. 10 μM of PI3K/mTOR Inhibitor-6 significantly inhibits the PI3K/Akt/mTOR signalli...
T62997 PI3K/AKT-IN-1
PI3K/AKT-IN-1 is a potent, dual PI3K/AKT inhibitor that acts on PI3Kγ (IC50: 6.99 μM), PI3Kδ (IC50: 4.01 μM) and AKT (IC50: 3.36 μM). PI3K/AKT-IN-1 induces caspase 3-dependent apoptosis by inhibiting the PI3K/AKT pathway...
T74361 MEK/PI3K-IN-2
MEK/PI3K-IN-2 (compound 6s) is a potent MEK/PI3K inhibitor, with IC 50 values of 352 nM (MEK1), 107 nM (PI3Kα), and 137 nM (PI3Kδ), respectively. MEK/PI3K-IN-2 suppresses pAKT and pERK1/2 levels. MEK/PI3K-IN-2 shows anti...
T74360 MEK/PI3K-IN-1
MEK/PI3K-IN-1 (compound 6r) is a potent MEK/PI3K inhibitor, with IC 50 values of 124 nM (MEK1), 130 nM (PI3Kα), and 236 nM (PI3Kδ), respectively. MEK/PI3K-IN-1 suppresses pAKT and pERK1/2 levels. MEK/PI3K-IN-1 shows anti...
T61516 PI3K/mTOR Inhibitor-3
PI3K/mTOR Inhibitor-3 (compound 12) is an imidazoline compound with potent dual inhibitory effects on PI3K and mTOR. This compound exhibits notable anti-cancer activity [1].
T81470 PI3K/mTOR Inhibitor-14 PI3K
PI3K/mTOR Inhibitor-14 (compound Y-2) serves as a dual inhibitor of PI3K and mTOR, exhibiting IC50 values of 171.4 nM and 10.1 nM , respectively, and demonstrates antitumor activities [1].
T62912 PI3K/HDAC-IN-2
PI3K/HDAC-IN-2 is a potent dual PI3K/HDAC inhibitor, capable of acting on PI3Kα (IC50: 226 nM), PI3Kβ (IC50: 279 nM), PI3Kγ (IC50: 467 nM), PI3Kδ (IC50: 29 nM), HDAC1 (IC50: 1.3 nM), and PI3K/HDAC-IN-2 is PI3Kδ and class...
T72713 PI3K/VEGFR2-IN-1 PI3K
PI3K/VEGFR2-IN-1 is a potent dual inhibitor targeting both PI3K and VEGFR2 with IC50 values of 2.21 μM for PI3K and 68 μM for VEGFR2, respectively. This compound also induces apoptosis and is utilized in cancer research ...
T72880 PI3K/AKT-IN-2
PI3K/AKT-IN-2 is a PI3K and AKT inhibitor. PI3K/AKT-IN-2 blocks the epithelial-mesenchymal transition (EMT) and induces apoptosis . PI3K/AKT-IN-2 inhibits the polymerization of tubulin .
T63770 PI3K/mTOR Inhibitor-4
PI3K/mTOR Inhibitor-4 is an orally active pan-I PI3K/mTOR inhibitor. PI3K/mTOR Inhibitor-4 is an enzyme inhibitor that acts on PI3Kα (IC50: 0.63 nM), PI3Kγ (IC50: 22 nM), PI3Kδ (IC50: 9.2 nM) and mTOR (IC50: 13.85 nM). P...
T72380 PI3K/mTOR Inhibitor-13
PI3K/mTOR Inhibitor-13 is an orally active dual inhibitor of phosphoinositol 3-kinase ( PI3K ) and mTOR kinase. PI3K/mTOR Inhibitor-13 has potential applications in sexual diseases, solid tumor and idiopathic pulmonary f...
T72374 PI3K/mTOR Inhibitor-12 PI3K
PI3K/mTOR Inhibitor-12, a potent and selective orally active inhibitor, exhibits IC50 values of 0.06 nM for PI3Kα and 3.12 nM for mTOR, indicating significant antitumor activity with reduced liver toxicity [1].

Compounds

PI3K-IN-46
T64392
Synonym:
Target: PI3K
PI3K/mTOR Inhibitor-2
T12459
Synonym:
Target: PI3K, mTOR
PARP/PI3K-IN-1
T12365
Synonym:
Target: PARP, PI3K
PI3K-IN-1
T1826
Synonym: Voxtalisib Analogue,Voxtalisib (SAR245409, XL765) Analogue,XL765,SAR245409
Target: DNA-PK, PI3K
PI3K-IN-38
T61618
Synonym:
Target: PI3K
PI3K-IN-19 hydrochloride
T39581
Synonym: PI3K-IN-19 hydrochloride
Target:
Bimiralisib
T2265
Synonym: 5-(4,6-dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine,PQR309,PI3K-IN-2
Target: Others, PI3K, S6 Kinase, mTOR
PI3K inhibitor C 96
T24637
Synonym: PI3K IN C96,PI3K-IN-C96
Target:
PI3K/Akt/mTOR-IN-2
T60564
Synonym:
Target: Apoptosis, Akt, PI3K, mTOR
Fimepinostat
T2078
Synonym: CUDC-907,PI3K/HDAC Inhibitor,CUDC 907
Target: Apoptosis, PI3K, HDAC
PI3K-IN-22
T36087
Synonym: CAY10626
Target:
PI3K-IN-10
T12456
Synonym:
Target: PI3K
PI3K-IN-6
T12457
Synonym:
Target: PI3K
PI3K-IN-9
T12458
Synonym:
Target: PI3K
PI3K/HDAC-IN-1
T12455
Synonym:
Target: PI3K
PI3K/mTOR Inhibitor-1
T12460
Synonym:
Target: PI3K
PI3K/Akt-IN-C89
T71272
Synonym:
Target:
PI3K-IN-37
T62580
Synonym:
Target:
PI3K-IN-36
T73150
Synonym:
Target:
PI3K-IN-27
T64052
Synonym:
Target:
PI3K-IN-48
T79701
Synonym:
Target: Akt
PI3K-IN-47
T78853
Synonym:
Target: PI3K
PI3K-IN-34
T62392
Synonym:
Target:
PI3K-IN-33
T63323
Synonym:
Target:
PI3K-IN-26
T61966
Synonym:
Target:
PI3K-IN-41
T79566
Synonym:
Target: PI3K
PI3K-IN-30
T62696
Synonym:
Target:
PI3K-IN-2
T63682
Synonym:
Target:
PI3K/mTOR Inhibitor-7
T64041
Synonym:
Target:
PI3K/mTOR Inhibitor-8
T63470
Synonym:
Target:
PI3K/mTOR Inhibitor-5
T72408
Synonym:
Target:
PI3K/mTOR Inhibitor-9
T62438
Synonym:
Target:
PI3K-IN-35
T62779
Synonym:
Target:
PI3K-IN-29
T63957
Synonym:
Target:
PI3K-IN-31
T62470
Synonym:
Target:
PI3K-IN-28
T73118
Synonym:
Target:
PI3K-IN-23
T62409
Synonym:
Target:
IHMT-PI3K-455
T78836
Synonym:
Target: PI3K
PI3K/mTOR Inhibitor-6
T64219
Synonym:
Target:
PI3K/AKT-IN-1
T62997
Synonym:
Target:
MEK/PI3K-IN-2
T74361
Synonym:
Target:
MEK/PI3K-IN-1
T74360
Synonym:
Target:
PI3K/mTOR Inhibitor-3
T61516
Synonym:
Target:
PI3K/mTOR Inhibitor-14
T81470
Synonym:
Target: PI3K
PI3K/HDAC-IN-2
T62912
Synonym:
Target:
PI3K/VEGFR2-IN-1
T72713
Synonym:
Target: PI3K
PI3K/AKT-IN-2
T72880
Synonym:
Target:
PI3K/mTOR Inhibitor-4
T63770
Synonym:
Target:
PI3K/mTOR Inhibitor-13
T72380
Synonym:
Target:
PI3K/mTOR Inhibitor-12
T72374
Synonym:
Target: PI3K
1 2 3 4 5 6 7 8
Cat No. Product Name Synonyms Targets
T5654 Musk ketone Others
Musk ketone can induce the growth repression and the apoptosis of cancer cells. Musk ketone increases activity of glutathione S-transferase and thus may prove to be useful cancer chemoprotectant.
T4S1796 Heterophyllin B PI3K
Heterophyllin B effectively suppresses the adhesion and invasion of the human esophageal carcinoma cells by mediating the PI3K/AKT/β-catenin pathways and regulating the expression levels of adhesion- and invasion-associa...
TN1891 Lupiwighteone Apoptosis , BCL , PARP , Caspase
Lupiwighteone has anti-angiogenesis potential, it also has anticancer and cancer preventive effects on SH-SY5Y cells.
TN1134 Euscaphic acid Apoptosis , LDL , PI3K , DNA/RNA Synthesis , NO Synthase , Prostaglandin Receptor
Euscaphic acid has anti-diabetic, and anti-inflammatory activities, it inhibits LPS-induced inflammatory responses by interference with the clustering of TRAF6 with IRAK1 and TAK1, resulting in blocking the activation of...
T6677 Sophocarpine ERK , p38 MAPK , NF-κB , TLR , COX , HER , JNK , STAT
Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.
TN4673 (+)-Nortrachelogenin Wikstromol Apoptosis , HIV Protease , PI3K , Antifection
(+)-Nortrachelogenin is a lignan isolated from Wikstroemia indica C.A. Meyer (Thymelaeaceae). (+)-Nortrachelogenin possesses antileukemic activity.
T6630 Quercetin Dihydrate Sophoretin Apoptosis , PI3K
Quercetin Dihydrate (Sophoretin) is a polyphenolic flavonoid that was found in a wide variety of plant-based foods, such as apples, onions, berries, and red wine. It is used for their nervous system and anticancer effect...
TN1079 Deoxyelephantopin NF-κB
Deoxyelephantopin has anti-inflammatory, hepatoprotective, and wound healing activities; it also has antitumor activity.Deoxyelephantopin inhibits NF-κB, MAPK, PI3K/Akt, and β-catenin signaling
T2174 Quercetin Sophoretin Apoptosis , Mitophagy , Reactive Oxygen Species , PI3K , Autophagy
Quercetin (Sophoretin) is a natural flavonoid and is an agonist of SIRT1. Quercetin is also a PI3K inhibitor, inhibiting PI3Kγ, PI3Kδ, and PI3Kβ (IC50=2.4/3.0/5.4 μM). Quercetin can induce apoptosis and autophagy.
T5S1982 Periplocin Periplocoside Apoptosis , Others
1. Periplocin (Periplocoside) has anti-cancer effects on lung cancer cells, induces apoptosis and inhibits growth of cancer cells by the beta-catenin/Tcf signaling pathway. 2. Periplocin is used for treatment of rheumato...
TN1644 Flavanomarein Others
Flavanomarein demonstrates potent antioxidative property, including free radical scavenging activity, inhibition of lipid peroxidation, as well as lipid-lowering effects in human HepG2 hepatocellular carcinoma cells trea...
T2791 Pectolinarin Apoptosis , Others , NO Synthase , Prostaglandin Receptor , Interleukin
Pectolinarin is a Cirsium isolate with anti-inflammatory activity.
T3780 Oroxin B Hypocretin-2 Apoptosis , PTEN , Antioxidant , PI3K , Autophagy
Oroxin B (Hypocretin-2) has antioxidant activity.
T2798 Esculetin Aesculetin,Cichorigenin Lipoxygenase , Akt , PI3K
Esculetin (Cichorigenin) is a coumarin derivative from various natural plant products with various biological and pharmaceutical properties including anti-edema, anti-inflammatory and anti-tumour effects. It inhibits lip...
T4867 Erucic acid Prifac 2990,13(Z)-Docosenoic Acid,cis-13-docosenoic acid PI3K , Endogenous Metabolite
Increased levels of erucic acid (22:1n9) have been found in the red blood cell membranes of autistic subjects with developmental regression (PMID: 16581239 ). Erucic acid (13(Z)-Docosenoic Acid) is broken down long-chain...
T4S0498 Glaucocalyxin A Wangzaozin B,Leukamenin F Apoptosis , Akt , Caspase , PI3K
1. Glaucocalyxin A (Leukamenin F)-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery. 2. Glaucocalyxin A activates caspase-3, decreases BAD phosphorylation, and reduces the expressi...
T2746 Sophocarpine monohydrate Sophocarpine Apoptosis , Influenza Virus , Akt , PI3K , AMPK , Autophagy
Sophocarpine monohydrate, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.
T4727 Taurolithocholic acid sodium salt Sodium taurolithocholate Others , Calcium Channel
Taurolithocholic acid sodium salt (Sodium taurolithocholate) is the major human metabolite, a bile acid which inhibits radioligand binding to muscarinic M1, but not to M2 or M3 receptors.
TN4761 Phellamurin P-gp
Phellamurin inhibits intestinal P-glycoprotein in a dose-dependent manner, there is a serious interaction occurred between Phellamurin with cyclosporin, to ensure the efficacy of cyclosporin, we suggest that the coadmini...
TN1405 Arnicolide D Akt , Caspase , PI3K , STAT , mTOR
Arnicolide D is a sesquiterpene lactone. Arnicolide D isolates from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling pathway and inhibits the PI3K/AKT/mTOR and STAT3 signaling path...
T3826 Polygalasaponin F NF-κB , TLR , Akt , PI3K
Polygalasaponin F has anti-neuroinflammatory activity, can inhibit the release of inflammatory cytokines TNF-α and NO induced by lipopolysaccharides (LPS) and reduce the expression of inducible nitric oxide synthases. Po...
T1879 3-Methyladenine 3-MA,NSC 66389 Mitophagy , PI3K , Endogenous Metabolite , Autophagy
3-Methyladenine (3-MA) is a PI3K inhibitor that selectively inhibits class IB PI3Kγ (IC50=60 μM) and class III VPS34 (IC50=25 μM). 3-Methyladenine inhibits autophagy.
T3675 1-Deoxynojirimycin Duvoglustat,Moranoline,moranolin PI3K , Glucosidase
1-Deoxynojirimycin (Moranoline) is a potent α-glucosidase inhibitor, suppressing postprandial blood glucose, thereby possibly preventing diabetes mellitus.
TL0006 Cichoric Acid Dicaffeoyltartaric acid,Chicoric Acid Reactive Oxygen Species , HIV Protease
Cichoric Acid (Dicaffeoyltartaric acid) is a potent inhibitor of human immunodeficiency virus type-1 (HIV-1) integrase and the replication in tissues. It also a class of cannabinomimetics with CB2 receptor-dependent and ...
T2836 Isorhamnetin 3-methylquercetin,3'-Methylquercetin,Isorhamnetol,3'-Methoxyquercetin MEK , PI3K , Endogenous Metabolite
Isorhamnetin (3-methylquercetin) is the methylated metabolite of quercetin. Quercetin is an important dietary flavonoid with in vitro antioxidant activity. Isorhamnetin prevents endothelial cell injuries from oxidized LD...
T5740 25(R,S)-Ruscogenin (25RS)-Ruscogenin Others , HIF
25(R,S)-Ruscogenin is a natual product.
T8160 EGCG Octaacetate Others , Antibacterial
EGCG Octaacetate, a prodrug of EGCG, is utilized to enhance the stability and bioavailability of EGCG in vivo. It has high efficacy, bioavailability, anti-oxidation, and anti-angiogenesis capacities.
TN1299 Desmethylglycitein 6,7,4'-Trihydroxyisoflavone PI3K , CDK , PKC
Desmethylglycitein (6,7,4'-Trihydroxyisoflavone) , is a novel inhibitor of PKCα in suppressing solar UV-induced matrix metalloproteinase 1, which has antioxidant, and anti-cancer activities.
T2P2806 Hederacolchiside A1 Raddeanoside R13 Apoptosis , ERK , MEK , Akt , PI3K , Parasite , mTOR
Hederacolchiside A1 (Raddeanoside R13) shows anti-leishmanial activity, it exhibits a strong antiproliferative activity on all stages of development of the parasite by altering membrane integrity and potential. Hederacol...
TN3500 Beta-Amyrone β-Amyron COX , AChR , PPAR , Antifection
beta-Amyrone (β-Amyron) has antifungal activity against Chikungunya virus replication with an EC50 of 86 uM. beta-Amyrone has anti-inflammatory activity through inhibiting the expression of COX-2. beta-Amyrone exhibits a...
T3P2904 α-Linolenic acid Alpha-Linolenic Acid,Linolenic acid Akt , PI3K
α-Linolenic acid (Alpha-Linolenic Acid) is an essential fatty acid belonging to the omega-3 fatty acids group. It is highly concentrated in certain plant oils and has been reported to inhibit the synthesis of prostagland...
TN2019 Orobol 3'-Hydroxygenistein,3’,4’,5,7-tetrahydroxy-isoflavon BCL , Caspase , PI3K
Orobol (3’,4’,5,7-tetrahydroxy-isoflavon) is an inhibitor of tyrosine-specific protein kinase and phosphatidylinositol turnover. Orobol inhibits PI3K isoforms with IC50s of 3.46-5.27 μM for PI3K α/β/γ/K/δ. Orobol exhibit...
T3208 Brevianamide F Cyclo-L-tryptophyl-L-proline,cyclo-(L-Trp-L-Pro),Cyclo(L-Pro-L-Trp) BCRP , PI3K , Antibacterial
Brevianamide F (Cyclo(L-Pro-L-Trp)), also known as cyclo-(L-Trp-L-Pro), belongs to a class of naturally occurring 2,5-diketopiperazines. Brevianamide F possess interesting breast cancer resistance protein inhibitory acti...
T21344 1-Deoxynojirimycin hydrochloride Moranoline,AT2220,Duvoglustat hydrochloride,1-Deoxynojirimycin,DNJ,deoxynojirimycin PI3K , Antibacterial , Antibiotic , Glucosidase
1-Deoxynojirimycin hydrochloride (Moranoline) is a potent and selective inhibitor of alpha-glucosidase, most commonly found in mulberry leaves. Duvoglustat is used to suppress the elevation of postprandial hyperglycemia.
T2163 Dihydrocapsaicin CCRIS1589,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide Others , TRP/TRPV Channel
Dihydrocapsaicin (CCRIS1589) is isolated from Capsicum fruit. Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Like capsaicin, dihydrocapsaicin is an...
T4S1499 Ginsenoside Rk1 Apoptosis , Others , NF-κB , PI3K , JAK
Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures. Ginsenoside Rk1 has an anti-inflammatory effect, suppresses the activation of Jak2/Stat3 signaling pathway and NF-κB. It also h...
T5736 1,3-Dicaffeoylquinic acid CYNARIN,Cyclohexanecarboxyli​c acid, 1,​3-​bis[[3-​(3,​4-​dihydroxyphenyl)​-​1-​oxo-​2-​propen-​1-​yl]​oxy]​-​4,​5-​dihydroxy-​, (1S,​3R,​4R,​5R)​-,1,3-O-Dicaffeoylquinic acid,1,5-Dicaffeoylquinic acid Reactive Oxygen Species , Akt , PI3K
1,3-Dicaffeoylquinic acid (CYNARIN) is a natural product. It shows antioxidant and choleretic properties and is a potential immunosuppressive agent.
T6817 Deguelin (-)-Deguelin,(-)-cis-Deguelin Apoptosis , Akt , PI3K , Autophagy
Deguelin ((-)-Deguelin) is a PI3K/AKT Inhibitor, which is a natural product isolated from plants in the Mundulea sericea family.
TN2259 Taurocholic acid N-Choloyltaurine TNF , PI3K
Taurocholic acid (N-Choloyltaurine) is a bile acid involved in the emulsification of fats.Taurocholic acid is cytoprotective, preventing tumor necrosis factor-alpha-induced cholangiocyte damage via a PI3K-mediated pathwa...
TN1507 Clematichinenoside AR TNF , Autophagy
Clematichinenoside AR exerts anti-inflammatory and immunosuppressive properties, it has anti-arthritic effects on PI3K/Akt signaling pathway and TNF-α± associated with collagen-induced arthritis.
TN1346 Oxypalmatine 8-Oxypalmatine Apoptosis
Oxypalmatine (8-Oxypalmatine) is a berberine-type alkaloid isolated from Phellodendron amurense that regulates breast cancer cell proliferation and apoptosis by inhibiting PI3K/AKT signaling and its efficacy in breast ca...
T6S1844 Tenacissoside H Tenacissimoside C Others
Tenacissoside H (Tenacissimoside C) has antitumor activity on esophageal cancer through arresting cell cycle and regulating PI3K/Akt-NF-κB transduction cascade.
T3890 Verbenalin Verbenalol β-D-glucopyranoside,Verbenaloside,Verbenalol glucoside,Cornin Others
Verbenalin (Verbenaloside) induces angiogenesis via a programmed PI3K/Akt/eNOS/VEGF signaling axis.
T16324 Nimbolide Apoptosis , NF-κB , CDK
Nimbolide suppresses CDK4/CDK6 kinase activity. Nimbolide inhibits the NF-κB, Wnt, PI3K-Akt, MAPK, and JAK-STAT signaling pathways. Nimbolide causes apoptosis through the inactivation of NF-κB. Nimbolide is a triterpene ...
TN2091 Polygalacin D Apoptosis , IAP
Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-induced iNOS and COX-2 protein and mRNA without an appreciable cytotoxi...
T3385 Gypenoside XVII GP-17,Gynosaponin S Estrogen Receptor/ERR , GSK-3 , Endogenous Metabolite
Gypenoside XVII (Gynosaponin S) confers protection against Aβ25-35-induced neurotoxicity through estrogen receptor-dependent activation of PI3K/Akt pathways, activation of Nrf2/ARE/HO-1 and inactivation of GSK-3β pathway...
T3330 Trans-Trimethoxyresveratrol trans-trismethoxy Resveratrol,E-Resveratrol Trimethyl Ether,MR-3,Tri-O-methylresveratrol,3,4',5-Trimethoxy-trans-stilbene,Trimethoxystilbene Reactive Oxygen Species
trans-Trimethoxyresveratrol (MR-3), a natural methoxylated analog of resveratrol, inhibits breast Y cell invasiveness by downregulation of PI3K/Akt and Wnt/β-catenin signaling cascades and reversal of epithelial-mesenchy...
T3S1701 Dihydrocurcumin PPAR , Fatty Acid Synthase
Dihydrocurcumin is the main metabolite of curcumin, which can reduce fat accumulation and oxidative stress response. Dihydrocurcumin can regulate the mRNA and protein expression levels of SREBP-1C, PNPLA3 and PPARα, incr...
TL0008 Gigantol Wnt/beta-catenin , Glucosidase
Gigantol is a novel inhibitor of the Wnt/β-catenin pathway. It inhibits Wnt/β-catenin signaling through downregulation of phosphorylated LRP6 and cytosolic β-catenin in breast cancer cells. Gigantol may be developed as a...
T2S2382 3'-Hydroxypterostilbene 3'-HPT Apoptosis , Autophagy
3'-Hydroxypterostilbene (3'-HPT), a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells with IC50s of 9.0, 40.2, and 70.9 μM for COLO 205, HCT-116, and HT-29 cells, respectively, b...
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Natural Products

Musk ketone
T5654
Synonym:
Target: Others
Heterophyllin B
T4S1796
Synonym:
Target: PI3K
Lupiwighteone
TN1891
Synonym:
Target: Apoptosis, BCL, PARP, Caspase
Euscaphic acid
TN1134
Synonym:
Target: Apoptosis, LDL, PI3K, DNA/RNA Synthesis, NO Synthase, Prostaglandin Receptor
Sophocarpine
T6677
Synonym:
Target: ERK, p38 MAPK, NF-κB, TLR, COX, HER, JNK, STAT
(+)-Nortrachelogenin
TN4673
Synonym: Wikstromol
Target: Apoptosis, HIV Protease, PI3K, Antifection
Quercetin Dihydrate
T6630
Synonym: Sophoretin
Target: Apoptosis, PI3K
Deoxyelephantopin
TN1079
Synonym:
Target: NF-κB
Quercetin
T2174
Synonym: Sophoretin
Target: Apoptosis, Mitophagy, Reactive Oxygen Species, PI3K, Autophagy
Periplocin
T5S1982
Synonym: Periplocoside
Target: Apoptosis, Others
Flavanomarein
TN1644
Synonym:
Target: Others
Pectolinarin
T2791
Synonym:
Target: Apoptosis, Others, NO Synthase, Prostaglandin Receptor, Interleukin
Oroxin B
T3780
Synonym: Hypocretin-2
Target: Apoptosis, PTEN, Antioxidant, PI3K, Autophagy
Esculetin
T2798
Synonym: Aesculetin,Cichorigenin
Target: Lipoxygenase, Akt, PI3K
Erucic acid
T4867
Synonym: Prifac 2990,13(Z)-Docosenoic Acid,cis-13-docosenoic acid
Target: PI3K, Endogenous Metabolite
Glaucocalyxin A
T4S0498
Synonym: Wangzaozin B,Leukamenin F
Target: Apoptosis, Akt, Caspase, PI3K
Sophocarpine monohydrate
T2746
Synonym: Sophocarpine
Target: Apoptosis, Influenza Virus, Akt, PI3K, AMPK, Autophagy
Taurolithocholic acid sodium salt
T4727
Synonym: Sodium taurolithocholate
Target: Others, Calcium Channel
Phellamurin
TN4761
Synonym:
Target: P-gp
Arnicolide D
TN1405
Synonym:
Target: Akt, Caspase, PI3K, STAT, mTOR
Polygalasaponin F
T3826
Synonym:
Target: NF-κB, TLR, Akt, PI3K
3-Methyladenine
T1879
Synonym: 3-MA,NSC 66389
Target: Mitophagy, PI3K, Endogenous Metabolite, Autophagy
1-Deoxynojirimycin
T3675
Synonym: Duvoglustat,Moranoline,moranolin
Target: PI3K, Glucosidase
Cichoric Acid
TL0006
Synonym: Dicaffeoyltartaric acid,Chicoric Acid
Target: Reactive Oxygen Species, HIV Protease
Isorhamnetin
T2836
Synonym: 3-methylquercetin,3'-Methylquercetin,Isorhamnetol,3'-Methoxyquercetin
Target: MEK, PI3K, Endogenous Metabolite
25(R,S)-Ruscogenin
T5740
Synonym: (25RS)-Ruscogenin
Target: Others, HIF
EGCG Octaacetate
T8160
Synonym:
Target: Others, Antibacterial
Desmethylglycitein
TN1299
Synonym: 6,7,4'-Trihydroxyisoflavone
Target: PI3K, CDK, PKC
Hederacolchiside A1
T2P2806
Synonym: Raddeanoside R13
Target: Apoptosis, ERK, MEK, Akt, PI3K, Parasite, mTOR
beta-Amyrone
TN3500
Synonym: β-Amyron
Target: COX, AChR, PPAR, Antifection
α-Linolenic acid
T3P2904
Synonym: Alpha-Linolenic Acid,Linolenic acid
Target: Akt, PI3K
Orobol
TN2019
Synonym: 3'-Hydroxygenistein,3’,4’,5,7-tetrahydroxy-isoflavon
Target: BCL, Caspase, PI3K
Brevianamide F
T3208
Synonym: Cyclo-L-tryptophyl-L-proline,cyclo-(L-Trp-L-Pro),Cyclo(L-Pro-L-Trp)
Target: BCRP, PI3K, Antibacterial
1-Deoxynojirimycin hydrochloride
T21344
Synonym: Moranoline,AT2220,Duvoglustat hydrochloride,1-Deoxynojirimycin,DNJ,deoxynojirimycin
Target: PI3K, Antibacterial, Antibiotic, Glucosidase
Dihydrocapsaicin
T2163
Synonym: CCRIS1589,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide
Target: Others, TRP/TRPV Channel
Ginsenoside Rk1
T4S1499
Synonym:
Target: Apoptosis, Others, NF-κB, PI3K, JAK
1,3-Dicaffeoylquinic acid
T5736
Synonym: CYNARIN,Cyclohexanecarboxyli​c acid, 1,​3-​bis[[3-​(3,​4-​dihydroxyphenyl)​-​1-​oxo-​2-​propen-​1-​yl]​oxy]​-​4,​5-​dihydroxy-​, (1S,​3R,​4R,​5R)​-,1,3-O-Dicaffeoylquinic acid,1,5-Dicaffeoylquinic acid
Target: Reactive Oxygen Species, Akt, PI3K
Deguelin
T6817
Synonym: (-)-Deguelin,(-)-cis-Deguelin
Target: Apoptosis, Akt, PI3K, Autophagy
Taurocholic acid
TN2259
Synonym: N-Choloyltaurine
Target: TNF, PI3K
Clematichinenoside AR
TN1507
Synonym:
Target: TNF, Autophagy
Oxypalmatine
TN1346
Synonym: 8-Oxypalmatine
Target: Apoptosis
Tenacissoside H
T6S1844
Synonym: Tenacissimoside C
Target: Others
Verbenalin
T3890
Synonym: Verbenalol β-D-glucopyranoside,Verbenaloside,Verbenalol glucoside,Cornin
Target: Others
Nimbolide
T16324
Synonym:
Target: Apoptosis, NF-κB, CDK
Polygalacin D
TN2091
Synonym:
Target: Apoptosis, IAP
Gypenoside XVII
T3385
Synonym: GP-17,Gynosaponin S
Target: Estrogen Receptor/ERR, GSK-3, Endogenous Metabolite
trans-Trimethoxyresveratrol
T3330
Synonym: trans-trismethoxy Resveratrol,E-Resveratrol Trimethyl Ether,MR-3,Tri-O-methylresveratrol,3,4',5-Trimethoxy-trans-stilbene,Trimethoxystilbene
Target: Reactive Oxygen Species
Dihydrocurcumin
T3S1701
Synonym:
Target: PPAR, Fatty Acid Synthase
Gigantol
TL0008
Synonym:
Target: Wnt/beta-catenin, Glucosidase
3'-Hydroxypterostilbene
T2S2382
Synonym: 3'-HPT
Target: Apoptosis, Autophagy

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-05592 ULBP-2 Protein, Human, Recombinant(aa 1-217, His&AVI),Biotinylated Human HEK293
NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein that belongs to the MHC class I family. ULBP2 / N2DL-2 is e...
TMPY-02333 ULBP-2 Protein, Human, Recombinant (His) Human HEK293
NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein that belongs to the MHC class I family. ULBP2 / N2DL-2 is e...
TMPY-02676 EGFR Protein, Mouse, Recombinant (His) Mouse HEK293
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-04818 EGFR Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-04529 EGFR Protein, Human, Recombinant (aa 668-1210, His & GST) Human Baculovirus-Insect Cells
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-00742 EGFR Protein, Human, Recombinant (His) Human HEK293
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPJ-00059 IL-7 Protein, Human, Recombinant (His) Human Human Cells
Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions...
TMPY-00996 PD-1 Protein, Mouse, Recombinant (His) Mouse HEK293
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr...
TMPY-05079 PD-1 Protein, Human, Recombinant (mFc) Human HEK293
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr...
TMPY-01146 Insulin Receptor Protein, Human, Recombinant (long isoform, His) Human HEK293
INSR (Insulin receptor), also known as CD22, is a transmembrane receptor that is activated by insulin. INSR belongs to the protein kinase superfamily and exists as a tetramer consisting of two alpha subunits and two beta...
TMPY-05260 PD-1 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr...
TMPY-05815 PD-1 Protein, Canine, Recombinant (His & Avi), Biotinylated Canine HEK293
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr...
TMPY-04342 PD-1 Protein, Canine, Recombinant (His) Canine HEK293
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr...
TMPY-00897 PD-1 Protein, Human, Recombinant (His) Human HEK293
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr...
TMPY-04898 PD-1 Protein, Human, Recombinant (hFc) Human HEK293
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr...
TMPY-05395 PD-1 Protein, Mouse, Recombinant (hFc) Mouse HEK293
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr...
TMPY-04933 PIK3IP1 Protein, Mouse, Recombinant (His) Mouse HEK293
PIK3IP1 contains 1 kringle domain and is a negative regulator of phosphatidylinositol-3-kinase (PI3K), suppresses the development of hepatocellular carcinoma. PI3K is a well-known regulator of cell division, motility, me...
TMPY-03111 PIK3IP1 Protein, Human, Recombinant (hFc) Human HEK293
PIK3IP1 contains 1 kringle domain and is a negative regulator of phosphatidylinositol-3-kinase (PI3K), suppresses the development of hepatocellular carcinoma. PI3K is a well-known regulator of cell division, motility, me...
TMPK-01034 SEMA4B Protein, Mouse, Recombinant (His) Mouse HEK293
Semaphorin 4B (SEMA4B) inhibits the invasion of non-small cell lung cancer (NSCLC) through PI3K-dependent suppression of MMP9 activation. SEMA4B may induce FoxO1 nuclear retention through suppressing PI3K/Akt signaling p...
TMPH-03034 MG218.1 homolog Protein, Mycoplasma pneumoniae, Recombinant (His & Myc) Mycoplasma pneumoniae E. coli
Bactericidal C-type lectin. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway.
TMPY-02758 ENTPD5 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Ectonucleoside triphosphate diphosphohydrolase 5 (ENTPD5), also known as CD39 antigen-like 4, ER-UDPase, Guanosine-diphosphatase ENTPD5, Nucleoside diphosphatase Uridine-diphosphatase ENTPD5. This hydrolase is expressed ...
TMPY-04276 ENTPD5 Protein, Mouse, Recombinant (His) Mouse Baculovirus-Insect Cells
Ectonucleoside triphosphate diphosphohydrolase 5 (ENTPD5), also known as CD39 antigen-like 4, ER-UDPase, Guanosine-diphosphatase ENTPD5, Nucleoside diphosphatase Uridine-diphosphatase ENTPD5. This hydrolase is expressed ...
TMPK-00136 ULBP-2 Protein, Human, Recombinant (His & Avi) Human HEK293
ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, E...
TMPK-00283 CA9/Carbonic Anhydrase IX Protein, Human, Recombinant (His & Avi) Human HEK293
CA9 is a member of the carbonic anhydrases' family, that is often expressed in cancer cells under hypoxic condition. CA9 expression potentially contributes to the regulation of cancer cell differentiation and mediates tu...
TMPH-00915 ALKAL2 Protein, Human, Recombinant (E. coli, His & Myc) Human E. coli
Plays a central role in autophagy. Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane traffickin...
TMPK-00524 CA9/Carbonic Anhydrase IX Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
CA9 is a member of the carbonic anhydrases' family, that is often expressed in cancer cells under hypoxic condition. CA9 expression potentially contributes to the regulation of cancer cell differentiation and mediates tu...
TMPJ-01271 PIK3IP1 Protein, Human, Recombinant (His) Human Human Cells
Phosphoinositide-3-kinase-interacting protein 1(PIK3IP1) is an enzyme that in humans is encoded by the PIK3IP1 gene.It is a negative regulator of phosphatidylinositol-3-kinase (PI3K), suppresses the development of hepato...
TMPH-02247 TRIM5 Protein, Human, Recombinant (B2M & His) Human E. coli
Insulin-sensitizing adipocyte-secreted protein (adipokine) that regulates glucose metabolism in liver and adipose tissue. Promotes glucose uptake in adipocytes and suppresses de novo glucose production in hepatocytes via...
TMPH-02248 TRIM72 Protein, Human, Recombinant (His & Myc) Human Baculovirus
Insulin-sensitizing adipocyte-secreted protein (adipokine) that regulates glucose metabolism in liver and adipose tissue. Promotes glucose uptake in adipocytes and suppresses de novo glucose production in hepatocytes via...
TMPY-05211 EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-375, His) Human Baculovirus-Insect Cells
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-02958 EGFR Protein, Rat, Recombinant (His) Rat HEK293
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-03724 EGFR Protein, Canine, Recombinant (His) Canine Baculovirus-Insect Cells
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-02675 EGFR Protein, Mouse, Recombinant (hFc) Mouse HEK293
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-06524 EGFR Protein, Feline, Recombinant (His) Feline Baculovirus-Insect Cells
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-05612 EGFR Protein, Human, Recombinant (aa 1-645, His & Avi), Biotinylated Human HEK293
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-05637 EGFR Protein, Human, Recombinant (aa 1-378, His & Avi), Biotinylated Human Baculovirus-Insect Cells
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-00128 EGFR Protein, Rhesus, Recombinant (hFc) Rhesus HEK293
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-05258 EGFR Protein, Human, Recombinant (Isoform Viii, hFc) Human Baculovirus-Insect Cells
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-01043 EGFR Protein, Human, Recombinant (hFc) Human HEK293
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-06593 EGFR Protein, Human, Recombinant (Isoform vIII, His & Avi), Biotinylated Human HEK293
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-06549 EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-378, His) Human HEK293
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-02334 ULBP-2 Protein, Human, Recombinant (hFc) Human HEK293
NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein that belongs to the MHC class I family. ULBP2 / N2DL-2 is e...
TMPJ-00352 CD98 Protein, Human, Recombinant (mFc) Human Human Cells
CD98 is a multifunctional glycoprotein that is involved in various biological processes such as amino acid transport, cell adhesion, diffusion, adhesion, and proliferation. CD98 can interact with CD147 to induce integrin...
TMPH-00977 DDX3X Protein, Human, Recombinant (B2M & His) Human E. coli
Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 initiates activation of G proteins G(i)/G(o) and beta-arrestin pathways in...
TMPH-01688 UCP1 Protein, Human, Recombinant (His & SUMO) Human E. coli
Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte ...
TMPH-03022 PstP Protein, Mycobacterium tuberculosis, Recombinant Mycobacterium tuberculosis E. coli
Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte ...
TMPH-01687 UCP1 Protein, Human, Recombinant (His) Human Yeast
Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte ...
TMPJ-00181 PD-1 Protein, Human, Recombinant (His & Avi), Biotinylated Human Human Cells
Programmed cell death protein 1(PDCD1) is a single-pass type I membrane protein and contains 1 Ig-like V-type domain. PD-1 is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 inhibits the T-cell pr...
TMPH-00926 MAOB Protein, Human, Recombinant (His) Human E. coli
Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis. Acts in concert with PTHLH/PTHRP to stimu...
TMPY-04574 AKT3 Protein, Mouse, Recombinant (aa 106-479, His & GST) Mouse Baculovirus-Insect Cells
v-akt murine thymoma viral oncogene homolog 3 (AKT3), also known as PKB-GAMMA, with AKT1/PKBalpha, AKT2/PKBbeta, are the memerbers of Akt kinase family, share extensive structural similarity and perform common as well as...
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ULBP-2 Protein, Human, Recombinant(aa 1-217, His&AVI),Biotinylated
TMPY-05592
Species: Human
Expression System: HEK293
ULBP-2 Protein, Human, Recombinant (His)
TMPY-02333
Species: Human
Expression System: HEK293
EGFR Protein, Mouse, Recombinant (His)
TMPY-02676
Species: Mouse
Expression System: HEK293
EGFR Protein, Cynomolgus, Recombinant (His)
TMPY-04818
Species: Cynomolgus
Expression System: HEK293
EGFR Protein, Human, Recombinant (aa 668-1210, His & GST)
TMPY-04529
Species: Human
Expression System: Baculovirus-Insect Cells
EGFR Protein, Human, Recombinant (His)
TMPY-00742
Species: Human
Expression System: HEK293
IL-7 Protein, Human, Recombinant (His)
TMPJ-00059
Species: Human
Expression System: Human Cells
PD-1 Protein, Mouse, Recombinant (His)
TMPY-00996
Species: Mouse
Expression System: HEK293
PD-1 Protein, Human, Recombinant (mFc)
TMPY-05079
Species: Human
Expression System: HEK293
Insulin Receptor Protein, Human, Recombinant (long isoform, His)
TMPY-01146
Species: Human
Expression System: HEK293
PD-1 Protein, Cynomolgus, Recombinant (His)
TMPY-05260
Species: Cynomolgus
Expression System: HEK293
PD-1 Protein, Canine, Recombinant (His & Avi), Biotinylated
TMPY-05815
Species: Canine
Expression System: HEK293
PD-1 Protein, Canine, Recombinant (His)
TMPY-04342
Species: Canine
Expression System: HEK293
PD-1 Protein, Human, Recombinant (His)
TMPY-00897
Species: Human
Expression System: HEK293
PD-1 Protein, Human, Recombinant (hFc)
TMPY-04898
Species: Human
Expression System: HEK293
PD-1 Protein, Mouse, Recombinant (hFc)
TMPY-05395
Species: Mouse
Expression System: HEK293
PIK3IP1 Protein, Mouse, Recombinant (His)
TMPY-04933
Species: Mouse
Expression System: HEK293
PIK3IP1 Protein, Human, Recombinant (hFc)
TMPY-03111
Species: Human
Expression System: HEK293
SEMA4B Protein, Mouse, Recombinant (His)
TMPK-01034
Species: Mouse
Expression System: HEK293
MG218.1 homolog Protein, Mycoplasma pneumoniae, Recombinant (His & Myc)
TMPH-03034
Species: Mycoplasma pneumoniae
Expression System: E. coli
ENTPD5 Protein, Human, Recombinant (His)
TMPY-02758
Species: Human
Expression System: Baculovirus-Insect Cells
ENTPD5 Protein, Mouse, Recombinant (His)
TMPY-04276
Species: Mouse
Expression System: Baculovirus-Insect Cells
ULBP-2 Protein, Human, Recombinant (His & Avi)
TMPK-00136
Species: Human
Expression System: HEK293
CA9/Carbonic Anhydrase IX Protein, Human, Recombinant (His & Avi)
TMPK-00283
Species: Human
Expression System: HEK293
ALKAL2 Protein, Human, Recombinant (E. coli, His & Myc)
TMPH-00915
Species: Human
Expression System: E. coli
CA9/Carbonic Anhydrase IX Protein, Cynomolgus, Recombinant (His)
TMPK-00524
Species: Cynomolgus
Expression System: HEK293
PIK3IP1 Protein, Human, Recombinant (His)
TMPJ-01271
Species: Human
Expression System: Human Cells
TRIM5 Protein, Human, Recombinant (B2M & His)
TMPH-02247
Species: Human
Expression System: E. coli
TRIM72 Protein, Human, Recombinant (His & Myc)
TMPH-02248
Species: Human
Expression System: Baculovirus
EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-375, His)
TMPY-05211
Species: Human
Expression System: Baculovirus-Insect Cells
EGFR Protein, Rat, Recombinant (His)
TMPY-02958
Species: Rat
Expression System: HEK293
EGFR Protein, Canine, Recombinant (His)
TMPY-03724
Species: Canine
Expression System: Baculovirus-Insect Cells
EGFR Protein, Mouse, Recombinant (hFc)
TMPY-02675
Species: Mouse
Expression System: HEK293
EGFR Protein, Feline, Recombinant (His)
TMPY-06524
Species: Feline
Expression System: Baculovirus-Insect Cells
EGFR Protein, Human, Recombinant (aa 1-645, His & Avi), Biotinylated
TMPY-05612
Species: Human
Expression System: HEK293
EGFR Protein, Human, Recombinant (aa 1-378, His & Avi), Biotinylated
TMPY-05637
Species: Human
Expression System: Baculovirus-Insect Cells
EGFR Protein, Rhesus, Recombinant (hFc)
TMPY-00128
Species: Rhesus
Expression System: HEK293
EGFR Protein, Human, Recombinant (Isoform Viii, hFc)
TMPY-05258
Species: Human
Expression System: Baculovirus-Insect Cells
EGFR Protein, Human, Recombinant (hFc)
TMPY-01043
Species: Human
Expression System: HEK293
EGFR Protein, Human, Recombinant (Isoform vIII, His & Avi), Biotinylated
TMPY-06593
Species: Human
Expression System: HEK293
EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-378, His)
TMPY-06549
Species: Human
Expression System: HEK293
ULBP-2 Protein, Human, Recombinant (hFc)
TMPY-02334
Species: Human
Expression System: HEK293
CD98 Protein, Human, Recombinant (mFc)
TMPJ-00352
Species: Human
Expression System: Human Cells
DDX3X Protein, Human, Recombinant (B2M & His)
TMPH-00977
Species: Human
Expression System: E. coli
UCP1 Protein, Human, Recombinant (His & SUMO)
TMPH-01688
Species: Human
Expression System: E. coli
PstP Protein, Mycobacterium tuberculosis, Recombinant
TMPH-03022
Species: Mycobacterium tuberculosis
Expression System: E. coli
UCP1 Protein, Human, Recombinant (His)
TMPH-01687
Species: Human
Expression System: Yeast
PD-1 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00181
Species: Human
Expression System: Human Cells
MAOB Protein, Human, Recombinant (His)
TMPH-00926
Species: Human
Expression System: E. coli
AKT3 Protein, Mouse, Recombinant (aa 106-479, His & GST)
TMPY-04574
Species: Mouse
Expression System: Baculovirus-Insect Cells
Cat No. Product Name
L1300 PI3K-AKT-mTOR Compound Library

425 compounds
A unique collection of 425 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with PI3K/Akt/mTOR signaling;
L2195 Anti-Prostate Cancer Compound Library

2096 compounds
2096 compounds associated with prostate cancer that can be used for high-throughput and high-content screening.
L2193 Anti-Liver Cancer Compound Library

1816 compounds
1816 species of compounds related to liver cancer that can be used in anti-liver cancer drug development and pharmacological studies.
L3600 Cytokine Inhibitor Library

613 compounds
A unique collection of 613 compounds targeting cytokine signaling for high throughput screening and high content screening for drug discovery;
L2192 Anti-Pancreatic Cancer Compound Library

2267 compounds
A unique collection of 2267 pancreatic cancer related compounds can be used in HTS and HCS;
L8500 HIF-1 Signaling Pathway Compound Library

1352 compounds
A unique collection of 1352 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies;
TargetMol