Search Result

Search Results for " oxygen "

Targets

Reactive Oxygen Species Indoleamine 2,3-Dioxygenase (IDO) Lipoxygenase Others

319

Compounds

208

Natural Products

102

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
TP1344	Luciferase		Others
	Luciferase is a flavin-dependent monooxygenase found in bioluminescent bacteria. Luciferase is an invaluable tool for identifying and characterizing functional variants, allowing investigations of gene expression, intrac...		Others
T16951	Sulcotrione		Reactive Oxygen Species
	Sulcotrione is a β-triketone herbicide. It also can inhibit hydroxyphenylpyruvate dioxygenase.		Reactive Oxygen Species
T5426	DMNQ		Reactive Oxygen Species , ROS
	DMNQ is a 1,4-naphthoquinone that acts as a redox-cycling agent, typically increasing intracellular superoxide and hydrogen peroxide formation.DMNQ increases ROS generation		Reactive Oxygen Species , ROS
T1710	Trolox		Apoptosis , Antioxidant , Ferroptosis , Reactive Oxygen Species
	Trolox is a vitamin E analogue, used in reducing oxidative stress or damage.
T32648	Leptophos oxon	Leptophos OA,Leptophos oxygen analog,Phosvel oxon,Velsicol VCS O-analog
	Leptophos oxon is a phosvel analog-oxygen substituting sulfur.
T9045	Bemotrizinol		Others
	Bemotrizinol is a UVA absorber used as a topical sunscreen.		Others
T15030	CycLuc1		Others
	CycLuc1 is a brain penetrant luciferase substrate. CycLuc1 may be a superior BLI substrate as compared to D-luciferin for monitoring tumor growth of intracranial GBM xenografts.		Others
T3496	Buprofezin	NNI 750,Applaud,Buprofezine	Reactive Oxygen Species
	Buprofezin (Applaud) is an insecticide used for control of insect pests such as mealybugs, leafhoppers and whitefly on vegetable crops.		Reactive Oxygen Species
T3952	TPEN	TPEDA	Apoptosis , Reactive Oxygen Species , Autophagy
	TPEN (TPEDA) is a specific cell-permeable heavy metal chelator.		Apoptosis , Reactive Oxygen Species , Autophagy
T5116	Iprodione		Others , Reactive Oxygen Species , Antifungal
	Iprodione is a fungicide. Iprodione is also used in cannabis testing kits as a component of pesticide mixes.		Others , Reactive Oxygen Species , Antifungal
T5966	Hexaconazole	(-)-Hexaconazol	Reactive Oxygen Species , Antifungal
	Hexaconazole ((-)-Hexaconazol) is a broad-spectrum triazole fungicide that inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14α-demethylation of lanosterol, which results in disruption of ...		Reactive Oxygen Species , Antifungal
T19428	Mito-TEMPO		Reactive Oxygen Species , Mitochondrial Metabolism
	Mito-TEMPO is a mitochondria-targeted superoxide dismutase mimetic. Mito-TEMPO scavenges superoxide and alkyl radicals and prevents mitochondrial oxidation, necrosis and apoptosis.		Reactive Oxygen Species , Mitochondrial Metabolism
TD0102	1,3-Diphenylisobenzofuran	DPBF	Others
	1,3-Diphenylisobenzofuran (DPBF) is a fluorescent probe. It possesses a highly specific reactivity towards singlet oxygen forming an endoperoxide which decomposes to give 1,2-dibenzoylbenzene. 1,3-Diphenylisobenzofuran c...		Others
T5518	N-acetylcysteine amide		Reactive Oxygen Species , ROS
	N-Acetylcysteine amide is a thiol antioxidant and neuroprotective agent that can permeate cell membranes and the blood-brain barrier.		Reactive Oxygen Species , ROS
T4168	Visomitin	SKQ1	Reactive Oxygen Species
	Visomitin (SKQ1) is a mitochondria-targeted antioxidant that decreases transmembrane potential and production of reactive oxygen species (ROS).		Reactive Oxygen Species
T8370	GSK5182		Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Reactive Oxygen Species
	GSK5182 is a highly selective inverse estrogen-related receptor γ agonist (IC50 : 79 nM)
T7703	PK11007		Reactive Oxygen Species , p53
	PK11007 is an anti-p53 drug.		Reactive Oxygen Species , p53
T15433	GSK2795039		Apoptosis , Reactive Oxygen Species , ROS , NADPH
	GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption. GSK2795039 decreases apoptosis. GSK2795039 is an inhibitor of NADPH oxidase 2 (NOX2) (pIC50: 6 in different cell-free assays).		Apoptosis , Reactive Oxygen Species , ROS , NADPH
T38155	N-Acetyl-D-cysteine		Reactive Oxygen Species
	N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group.		Reactive Oxygen Species
T2090	Lexibulin	CYT-997	Apoptosis , Reactive Oxygen Species , Microtubule Associated
	Lexibulin (CYT-997)(CYT-997) is a potent tubulin polymerization inhibitor (IC50: 10-100 nM, in Y cell lines). Lexibulin blocks the formation of the mitotic spindle and leading to cell cycle arrest at the G2/M phase; this...
T13189	TP-10		PDE
	TP-10 is a selective inhibitor of PDE10A against other PDEs with IC50 of 0.8 nM.		PDE
T0756	Ethoxyquin	Santoquin,Quinol,Santoflex	HSP , Reactive Oxygen Species
	Ethoxyquin (Santoflex) is an antioxidant used in animal feeds.		HSP , Reactive Oxygen Species
T0418	Allylthiourea	N-Allylthiourea,Thiosinamine	MAO , Reactive Oxygen Species
	Allylthiourea (Thiosinamine), a metabolic inhibitor, specifically suppresses ammonia oxidation.		MAO , Reactive Oxygen Species
T11580	Heme Oxygenase-1-IN-1	HO-1-IN-1	Reactive Oxygen Species
	Heme Oxygenase-1-IN-1 (HO-1-IN-1) is a heme oxygenase 1 (HO-1) inhibitor (IC50: 250 nM).		Reactive Oxygen Species
T17250	W-54011		ROS , Complement System
	W-54011 is a potent non-peptide C5a receptor antagonist. W-54011 inhibits the binding of 125I-labeled C5a to human neutrophils (Ki: 2.2 nM). W-54011 inhibits C5a-induced intracellular Ca2+ mobilization, chemotaxis, and g...		ROS , Complement System
T8320	J14	J-14	Reactive Oxygen Species
	J-14 is an inhibitor of reversible sulfiredoxin(IC50 : 8.1 μM). J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin, leading to cytotoxicity and cancer cell death		Reactive Oxygen Species
T13019	Succinyl phosphonate trisodium salt		Dehydrogenase , Reactive Oxygen Species , Endogenous Metabolite
	Succinyl phosphonate trisodium salt is an inhibitor of α-ketoglutarate dehydrogenase (KGDHC)
T4287	Succinobucol	Probucol monosuccinate,AGI-1067	Antioxidant , Reactive Oxygen Species
	Succinobucol (Probucol monosuccinate) is a novel phenolic antioxidant small molecule with anti-oxidant and anti-inflammatory properties. It designed to treat atherosclerosis of the blood vessels of the heart or coronary ...		Antioxidant , Reactive Oxygen Species
T6482	Efaproxiral Sodium	RSR13 sodium	Reactive Oxygen Species
	Efaproxiral Sodium (RSR13 sodium), a synthetic allosteric modifier of hemoglobin, is utilized for brain metastases originating from breast cancer.		Reactive Oxygen Species
T0163	Nisoldipine	BAY-k 5552	Calcium Channel , Reactive Oxygen Species
	Nisoldipine (BAY-k 5552) is a dihydropyridine calcium channel antagonist that acts as a potent arterial vasodilator and antihypertensive agent.		Calcium Channel , Reactive Oxygen Species
T8377	Mesotrione		Reactive Oxygen Species
	Mesotrione is a selective triketone herbicide		Reactive Oxygen Species
T6699	Tempol	TMPN,Tanol,4-Hydroxy-TEMPO	Reactive Oxygen Species , ROS , Autophagy
	Tempol (Tanol) is a superoxide scavenger. It has anti-inflammatory, neuroprotective and analgesic effects.		Reactive Oxygen Species , ROS , Autophagy
T38423	CL097	CL097	Reactive Oxygen Species , TLR
	CL097 is an effective agonist of TLR7 and TLR8. CL097 induces pro-inflammatory cytokines in macrophages and NADPH oxidase priming, thereby increasing the fMLF-stimulated ROS production.		Reactive Oxygen Species , TLR
T21233	Dihydrolipoic acid	Reduced thioctic acid,Reduced lipoic acid,DHLA,USAF XR-12,6,8-Dihydrothioctic acid	Antioxidant
	Dihydrolipoic acid (USAF XR-12), a dithiol-containing carboxylic acid, acts as a general antioxidant that is highly reactive against a variety of reactive oxygen species, including peroxynitirite, hydroxyl radicals, hydr...		Antioxidant
T7191	Diphenyleneiodonium chloride	DPI	NOS , Reactive Oxygen Species , NADPH , TRP/TRPV Channel
	Diphenyleneiodonium chloride (DPI)(DPI) is an irreversible inhibitor of iNOS and eNOS (IC50 values of 50 nM and 0.3 μM, respectively),and displays broad-spectrum bactericidal activity.		NOS , Reactive Oxygen Species , NADPH , TRP/TRPV Channel
T21807	INCA-6	Triptycene-1,4-quinone	Others
	INCA-6 (Triptycene-1,4-quinone) is a cell-permeable NFAT inhibitor. INCA-6 inhibits of CN-NFAT signaling by targeting of NFAT(P) substrate to the calcineurin (CN) phosphatase site.		Others
T4172	Methoxy-PMS	1-Methoxyphenazine methosulfate,1-Methoxy PMS	Reactive Oxygen Species
	Methoxy-PMS (1-Methoxyphenazine methosulfate) is stable electron-transport mediator between NAD(P)H and tetrazolium dyes, can induce active oxygen formation.		Reactive Oxygen Species
T40612	Manganese(salen) chloride	EUK-8	Others
	Manganese(salen) chloride (EUK-8) (EUK-8) is a superoxide dismutase and catalase mimetic. Manganese(salen) chloride (EUK-8) is an antioxidant with oxyradical scavenging properties. Manganese(salen) chloride ameliorates a...		Others
T15213	Emeramide	BDTH2	Reactive Oxygen Species
	Emeramide (BDTH2) is a thiol-redox antioxidant. It is also a heavy metal chelator.		Reactive Oxygen Species
T2587	Ecabet Sodium	TA-2711E,TA-2711	Reactive Oxygen Species , Antibacterial
	Ecabet Sodium (TA-2711) is a potential new agent in the management of distal colitis.		Reactive Oxygen Species , Antibacterial
T7717	Sodium 2-oxopropanoate	Sodium pyruvate	Reactive Oxygen Species , Endogenous Metabolite
	Sodium 2-oxopropanoate (Sodium pyruvate) is a antioxidant potentially used to treatment of chronic obstructive pulmonary disease.		Reactive Oxygen Species , Endogenous Metabolite
T9211	Mito-LND	Mito-Loidamine	OXPHOS , Reactive Oxygen Species , Mitochondrial Metabolism , Autophagy
	Mito-LND (Mito-Loidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation.
T12059L	Mitoquinone mesylate	MitoQ mesylate,MitoQ10 mesylate	Reactive Oxygen Species
	Mitoquinone mesylate (MitoQ10 mesylate) is a TPP-based, mitochondrially targeted antioxidant to protect against oxidative damage.		Reactive Oxygen Species
T21011	Buspirone	Buspirone free base,Ansial	5-HT Receptor
	Buspirone (Buspirone free base) is an azaspiro compound which has a role as an anxiolytic drug, a sedative, a serotonergic agonist and an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor.		5-HT Receptor
T5030	Zofenopril calcium	SQ26991,Zofenopril (calcium)	RAAS , Reactive Oxygen Species
	Zofenopril calcium (SQ26991) is an antioxidant that acts as an angiotensin-converting enzyme inhibitor. ACE Zofenopril is a pro-drug designed to undergo metabolic hydrolysis yielding the active free sulfhydryl compound z...		RAAS , Reactive Oxygen Species
T6201	Disufenton sodium	Cerovive,NXY059,OKN007,NXY-059,NXY 059	Reactive Oxygen Species
	Disufenton sodium (NXY-059), a new-type nitrone, exhibits potently neuroprotective effects.		Reactive Oxygen Species
T50099	HIF-2α-IN-4		Others , HIF/HIF Prolyl-Hydroxylase
	HIF-2a translation inhibitor is a compound used as a molecular building block.		Others , HIF/HIF Prolyl-Hydroxylase
T5363	Tempo	2,2,6,6-Tetramethylpiperidinooxy	Free radical scavengers , Reactive Oxygen Species , DNA/RNA Synthesis , Mitochondrial Metabolism
	Tempo (2,2,6,6-Tetramethylpiperidinooxy) has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as a structural probe in electron spin resonance spectroscopy.
T1057	Azilsartan	TAK-536	RAAS
	Azilsartan (TAK-536) is an Angiotensin 2 Receptor Blocker. The mechanism of action of azilsartan is as an Angiotensin 2 Type 1 Receptor Antagonist. The physiologic effect of azilsartan is by means of Decreased Blood Pres...		RAAS
T3103	L67	DNA Ligase Inhibitor	DNA , DNA/RNA Synthesis
	L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).		DNA , DNA/RNA Synthesis

Compounds

Target: Reactive Oxygen Species

DMNQ

T5426

Synonym:

Target: Reactive Oxygen Species, ROS

Trolox

T1710

Synonym:

Target: Apoptosis, Antioxidant, Ferroptosis, Reactive Oxygen Species

Leptophos oxon

T32648

Synonym: Leptophos OA,Leptophos oxygen analog,Phosvel oxon,Velsicol VCS O-analog

Synonym: NNI 750,Applaud,Buprofezine

Target: Reactive Oxygen Species

TPEN

T3952

Synonym: TPEDA

Target: Apoptosis, Reactive Oxygen Species, Autophagy

Iprodione

T5116

Synonym:

Target: Others, Reactive Oxygen Species, Antifungal

Hexaconazole

T5966

Synonym: (-)-Hexaconazol

Target: Reactive Oxygen Species, Antifungal

Mito-TEMPO

T19428

Synonym:

Target: Reactive Oxygen Species, Mitochondrial Metabolism

1,3-Diphenylisobenzofuran

TD0102

Synonym: DPBF

Target: Others

N-acetylcysteine amide

T5518

Synonym:

Target: Reactive Oxygen Species, ROS

Visomitin

T4168

Synonym: SKQ1

Target: Reactive Oxygen Species

GSK5182

T8370

Synonym:

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Reactive Oxygen Species

PK11007

T7703

Synonym:

Target: Reactive Oxygen Species, p53

GSK2795039

T15433

Synonym:

Target: Apoptosis, Reactive Oxygen Species, ROS, NADPH

N-Acetyl-D-cysteine

T38155

Synonym:

Target: Reactive Oxygen Species

Lexibulin

T2090

Synonym: CYT-997

Target: Apoptosis, Reactive Oxygen Species, Microtubule Associated

Synonym: Santoquin,Quinol,Santoflex

Target: HSP, Reactive Oxygen Species

Allylthiourea

T0418

Synonym: N-Allylthiourea,Thiosinamine

Target: MAO, Reactive Oxygen Species

Heme Oxygenase-1-IN-1

T11580

Synonym: HO-1-IN-1

Target: Reactive Oxygen Species

W-54011

T17250

Synonym:

Target: ROS, Complement System

J14

T8320

Synonym: J-14

Target: Reactive Oxygen Species

Succinyl phosphonate trisodium salt

T13019

Synonym:

Target: Dehydrogenase, Reactive Oxygen Species, Endogenous Metabolite

Succinobucol

T4287

Synonym: Probucol monosuccinate,AGI-1067

Target: Antioxidant, Reactive Oxygen Species

Efaproxiral Sodium

T6482

Synonym: RSR13 sodium

Target: Reactive Oxygen Species

Nisoldipine

T0163

Synonym: BAY-k 5552

Target: Calcium Channel, Reactive Oxygen Species

Mesotrione

T8377

Synonym:

Target: Reactive Oxygen Species

Tempol

T6699

Synonym: TMPN,Tanol,4-Hydroxy-TEMPO

Target: Reactive Oxygen Species, ROS, Autophagy

CL097

T38423

Synonym: CL097

Target: Reactive Oxygen Species, TLR

Dihydrolipoic acid

T21233

Synonym: Reduced thioctic acid,Reduced lipoic acid,DHLA,USAF XR-12,6,8-Dihydrothioctic acid

Target: Antioxidant

Diphenyleneiodonium chloride

T7191

Synonym: DPI

Target: NOS, Reactive Oxygen Species, NADPH, TRP/TRPV Channel

INCA-6

T21807

Synonym: Triptycene-1,4-quinone

Target: Others

Methoxy-PMS

T4172

Synonym: 1-Methoxyphenazine methosulfate,1-Methoxy PMS

Target: Reactive Oxygen Species

Manganese(salen) chloride

Target: Reactive Oxygen Species

Ecabet Sodium

T2587

Synonym: TA-2711E,TA-2711

Target: Reactive Oxygen Species, Antibacterial

Sodium 2-oxopropanoate

T7717

Synonym: Sodium pyruvate

Target: Reactive Oxygen Species, Endogenous Metabolite

Mito-LND

T9211

Synonym: Mito-Loidamine

Target: OXPHOS, Reactive Oxygen Species, Mitochondrial Metabolism, Autophagy

Mitoquinone mesylate

T12059L

Synonym: MitoQ mesylate,MitoQ10 mesylate

Target: Reactive Oxygen Species

Buspirone

T21011

Synonym: Buspirone free base,Ansial

Target: 5-HT Receptor

Zofenopril calcium

T5030

Synonym: SQ26991,Zofenopril (calcium)

Target: RAAS, Reactive Oxygen Species

Disufenton sodium

T6201

Synonym: Cerovive,NXY059,OKN007,NXY-059,NXY 059

Target: Reactive Oxygen Species

HIF-2α-IN-4

T50099

Synonym:

Target: Others, HIF/HIF Prolyl-Hydroxylase

Tempo

T5363

Synonym: 2,2,6,6-Tetramethylpiperidinooxy

Target: Free radical scavengers, Reactive Oxygen Species, DNA/RNA Synthesis, Mitochondrial Metabolism

Synonym: DNA Ligase Inhibitor

Target: DNA, DNA/RNA Synthesis

Cat No.	Product Name	Synonyms	Targets
TQ0212	Glucoraphanin		Antioxidant , Reactive Oxygen Species
	Glucoraphanin, the precursor of the widely extolled chemopreventive agent sulforaphane found in broccoli, has antioxidant activity.		Antioxidant , Reactive Oxygen Species
T1716	Echinacoside		Reactive Oxygen Species , Wnt/beta-catenin
	Echinacoside is a natural polyphenolic compound with various kinds of pharmacological activities, such as anti-inflammatory, antioxidative, hepatoprotective, neuroprotective, nitric oxide radical-scavenging and vasodilat...		Reactive Oxygen Species , Wnt/beta-catenin
T3S1692	Octahydrocurcumin		Anti-infection , NF-κB , Reactive Oxygen Species , ROS
	Octahydrocurcumin has antioxidant and and anti-inflammatory activities, it can inhibit the lipopolysaccharide (LPS)-induced inflammatory response via the mechanism of inhibiting NF-kB translocation to the nucleus. Octahy...		Anti-infection , NF-κB , Reactive Oxygen Species , ROS
TN1403	Arjunolic acid		IL Receptor , TNF , Reactive Oxygen Species , JNK , AChE
	Arjunolic acid has antioxidant, anti-inflammatory, antinociceptive and anticholinesterasic (AChE and BuChE) activities, it may as promising targets for the development of innovative multi-functional medicines for Alzheim...		IL Receptor , TNF , Reactive Oxygen Species , JNK , AChE
TQ0288	Hexahydrocurcumin		Reactive Oxygen Species , ROS , COX
	Hexahydrocurcumin is a selective, orally active COX-2 inhibitor and inactive against COX-1.		Reactive Oxygen Species , ROS , COX
T16747	Riboflavin Tetrabutyrate		Reactive Oxygen Species
	Riboflavin Tetrabutyrate is a lipophilic flavin derivative. Riboflavin Tetrabutyrate has antioxidative and lipid peroxide-removing activity.		Reactive Oxygen Species
T6S2038	Ziyuglycoside II		Apoptosis , Antioxidant , Reactive Oxygen Species
	1. Ziyuglycoside II has anti-inflammation and antioxidation properties. 2. Ziyuglycoside II has antibiosis, and homeostasis properties. 3. Ziyuglycoside II has anticancer, and antitumor properties against gastric cancer ...		Apoptosis , Antioxidant , Reactive Oxygen Species
T3399	Psoralidin		Others , Estrogen/progestogen Receptor , Reactive Oxygen Species , Lipoxygenase , Gamma-secretase , Akt , COX , Antibacterial
	Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally. Psoralidin possesses anticancer and chemopreventive properties.
T2866	Echinocystic acid		Apoptosis , Antioxidant , Reactive Oxygen Species
	Echinocystic acid (EA), a natural triterpone enriched in various herbs, shows a range of pharmacological activities including anti-inflammatory and antioxidant effects.		Apoptosis , Antioxidant , Reactive Oxygen Species
T2818	Methyl Vanillate		Reactive Oxygen Species , Wnt/beta-catenin , Endogenous Metabolite
	Methyl vanillate is Hovenia Dulcis Thunb extract and its ingredient methyl vanillate activate Wnt/β-catenin pathway and increase bone mass in growing or ovariectomized mice. Methyl vanillate is considered to be a slightl...
TN2167	Rutaevin		Reactive Oxygen Species , NO Synthase
	Rutaevin shows the inhibitory activity on nitric oxide (NO) production in lipopolysaccharide-activated RAW264.7 macrophages, it may be as a valuable anti-inflammatory agent.		Reactive Oxygen Species , NO Synthase
T8033	Sodium Thiocyanate		Others , Reactive Oxygen Species , Interleukin
	Sodium Thiocyanate, one of the main sources of the thiocyanate anion, is used as a precursor for the synthesis of pharmaceuticals and other specialty chemicals.		Others , Reactive Oxygen Species , Interleukin
T9057	Norbergenin		IL Receptor , TNF , Reactive Oxygen Species
	Norbergenin is a chemical compound. It is the O-demethylated derivative of bergenin. It can be isolated from rhizomes of Bergenia stracheyi.		IL Receptor , TNF , Reactive Oxygen Species
TN1058	Pelargonidin chloride		NOS , Reactive Oxygen Species , Nrf2 , NO Synthase
	Pelargonidin chloride shows protective effect against CTN-induced oxidative stress in HepG2 cells and up-regulated the activity of detoxification enzyme levels through Keap1/Nrf2 signaling pathway.		NOS , Reactive Oxygen Species , Nrf2 , NO Synthase
T10668	Camalexin		Reactive Oxygen Species , ROS , Antibacterial , Antifungal
	Camalexin is a phytoalexin isolated from Camelina sativa. It has antifungal, antibacterial, antiproliferative, and anticancer activities. Camalexin can induce ROS production.
TN1674	Garcinone D		Reactive Oxygen Species , Nrf2 , STAT
	Garcinone D shows significant cytotoxicity against the CEM-SS cell line, with IC(50) value of 3.2 microg/ml; it exhibits dose-dependent enzyme-based microsomal aromatase inhibitory activity. Garcinone D inhibits p65 acti...		Reactive Oxygen Species , Nrf2 , STAT
T0626	Uric Acid	2,6,8-Trioxopurine,2,6,8-Trioxypurine,2,6,8-Trihydroxypurine,Lithic acid,Urate	Reactive Oxygen Species , Endogenous Metabolite , Phosphorylase
	Uric Acid (Lithic acid) is an oxidation product of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE ...
TN6735	Bigelovin		Apoptosis , Reactive Oxygen Species , Retinoid Receptor , Autophagy , RAR/RXR
	Bigelovin is a selective retinoid X receptor α agonist. Bigelovin suppresses tumor growth through inducing apoptosis and autophagy via the inhibition of mTOR pathway regulated by ROS generation.It is also known as a pote...
T36735	3,5-Di-tert-butylphenol		Reactive Oxygen Species , Antifungal
	3,5-Di-tert-butylphenol induces accumulation of reactive oxygen species. 3,5-Di-tert-butylphenol exhibits anti-biofilm and antifungal activities.		Reactive Oxygen Species , Antifungal
T8347	Rifamycin S		Reactive Oxygen Species , ROS , Antibacterial , Antibiotic
	Rifamycin S is a potent DNA-dependent RNA polymerase inhibitor,is a quinone and an antibiotic agnet against Gram-positive bacteria
T4902	Isotrifoliin	Isoquercetin,Isoquercitroside	Reactive Oxygen Species
	Isotrifoliin (Isoquercitroside)n is an effective antioxidant and an eosinophilic inflammation suppressor.		Reactive Oxygen Species
T3332	Isosteviol	(-)-Isosteviol	IL Receptor , Potassium Channel , TNF , NF-κB , Reactive Oxygen Species , COX , Topoisomerase
	Isosteviol ((-)-Isosteviol), a common natural sweetener, belongs to tetracyclic diterpene glycosides. The pharmacology researches have suggested that stevioside and its hydrolysis products, steviol, isosteviol and stevio...
TN5634	Aureusidin	Auresudidin,Auresidin	Antioxidant , Reactive Oxygen Species , Lipoxygenase
	Aureusidin (Auresidin) shows antioxidant and lipoxygenase inhibitory activity with anti-inflammatory effects.		Antioxidant , Reactive Oxygen Species , Lipoxygenase
T0465	Ellagic acid	Gallogen,Elagostasine	Hedgehog/Smoothened , Casein Kinase , Reactive Oxygen Species , Topoisomerase , Endogenous Metabolite , PKA , Syk , PKC , Carbonic Anhydrase
	Ellagic acid (Gallogen) is a fused four ring compound isolated from the kino of Eucalyptus maculata Hook and E. Hemipholia F. Muell. Activates Factor XII of the blood clotting system which also causes kinin release; used...
T2174	Quercetin	Sophoretin	Apoptosis , Mitophagy , Reactive Oxygen Species , PI3K , Autophagy
	Quercetin (Sophoretin) is a natural flavonoid and is an agonist of SIRT1. Quercetin is also a PI3K inhibitor, inhibiting PI3Kγ, PI3Kδ, and PI3Kβ (IC50=2.4/3.0/5.4 μM). Quercetin can induce apoptosis and autophagy.
TN1651	Furanodiene		Apoptosis , PARP , Reactive Oxygen Species , Caspase , CDK , P-gp
	Furanodiene has anti-inflammatory and antioxidant activities, it is active against gram-positive bacteria and Candida albicans.
T3861	Isobavachalcone	Corylifolinin,Isobacachalcone	Apoptosis , Others , Reactive Oxygen Species , Akt , Autophagy
	Isobavachalcone (Corylifolinin) is a chalcone constituent of Angelica keiskei, has potent anti-inflammatory activity, possible can ameliorate neuronal injury in brain diseases associated with inflammation.
T2864	Lycopene	ψ,ψ-Carotene	Reactive Oxygen Species , ROS
	Lycopene (ψ,ψ-Carotene) is a linear, unsaturated hydrocarbon carotenoid, the major red pigment in fruits such as tomatoes, pink grapefruit, apricots, red oranges, watermelon, rosehips, and guava. As a class, carotenoids ...		Reactive Oxygen Species , ROS
T2834	Nobiletin	Hexamethoxyflavone	Apoptosis , MMP , Reactive Oxygen Species , ROR , Autophagy
	Nobiletin (Hexamethoxyflavone) is a natural polymethoxylated flavone isolated from citrus peels with anti-inflammatory and anti-tumor activities. Nobiletin is practically insoluble (in water) and an extremely weak acidic...
T6947	Piperlongumine	PPLGM,Piplartine	Apoptosis , ERK , Ferroptosis , Reactive Oxygen Species , ROS , Antibacterial , Autophagy
	Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L. It selectively kills cancer cells and strengthens the level of reactive oxygen species (ROS).
T6S1653	Albiflorin	Alibiflorin	Reactive Oxygen Species
	1. Albiflorin (Alibiflorin) has anticonvulsant effect for pain relief. 2. Albiflorin and paeoniflorin has neuroprotective action against Glu toxicity. 3. Albiflorin and paeoniflorin significantly ameliorated Glu-induced ...		Reactive Oxygen Species
T41358	2-Hydroxybenzylamine		Others
	2-Hydroxybenzylamine, a potent small molecule scavenger of IsoLGs, sequesters the reactive species as inert adducts. 2-Hydroxybenzylamine may be used to decrease early recurrence of atrial fibrillation and other atrial a...		Others
T4518	Licochalcone D		ERK , NF-κB
	Licochalcone D may be a potential drug for human melanoma treatment by inhibiting proliferation, inducing apoptosis via the mitochondrial pathway and blocking cell migration and invasion. Licochalcone D has cardioprotect...		ERK , NF-κB
T3429	Protopine	Macleyine,Hypercorine,Corydinine,Biflorine,Fumarine	Reactive Oxygen Species , Platelet aggregation , Histamine Receptor
	Protopine (Fumarine) is a benzylisoquinoline alkaloid. It has been found to inhibit histamine H1 receptors and platelet aggregation, and acts as an analgesic.
T8072	S-Methyl-L-cysteine	S-Methylcysteine	Antioxidant , Reactive Oxygen Species
	S-Methyl-L-cysteine (S-Methylcysteine) is a natural product that acts as a substrate in the catalytic antioxidant system mediated by methionine sulfoxide reductase A (MSRA), with neuroprotective, antioxidative, and anti-...		Antioxidant , Reactive Oxygen Species
T0480	Doxofylline	Doxophylline	PDE , Adenosine Receptor
	Doxofylline (Doxophylline) is a methylxanthine derivative with the presence of a dioxolane group in position 7. As a drug used in the treatment of asthma, doxofylline has shown similar efficacy to theophylline but with s...		PDE , Adenosine Receptor
T3240	Citronellol	dihydrogeraniol,(±)-β-Citronellol	Reactive Oxygen Species
	Citronellol ((±)-β-Citronellol) is used in insect repellents and perfumes and as a mite attractant.		Reactive Oxygen Species
T3744	Veratric acid	Veratrumenoic acid,3,4-Dimethoxybenzoic acid	Reactive Oxygen Species , COX
	Veratric acid (3,4-Dimethoxybenzoic acid) is a simple benzoic acid derived from plants and fruits with anti-oxidant, anti-inflammation and blood pressure-lowering effects.		Reactive Oxygen Species , COX
T5852	Canthaxanthin	all-trans-Canthaxanthin,E 161g	Reactive Oxygen Species
	Canthaxanthin (E 161g) is a red-orange carotenoid that belongs to the xanthophyll group. This naturally occurring pigment is present in bacteria, algae and some fungi.		Reactive Oxygen Species
T7781	Reynoutrin	Reinutrin,Quercetin-3-D-xyloside	Reactive Oxygen Species
	Reynoutrin (Reinutrin) with antioxidant and radical-scavenging activity.		Reactive Oxygen Species
T2992	Pinocembrin	5,7-Dihydroxyflavanone,Dihydrochrysin,Galangin flavanone	NF-κB , Reactive Oxygen Species , Antibacterial , Autophagy
	Pinocembrin (5,7-Dihydroxyflavanone) is a flavanone, a type of flavonoid. It is an antioxidant found in damiana, honey, fingerroot, and propolis.
T2796	Coenzyme Q10	Ubiquinone-10,CoQ10	Ferroptosis , Reactive Oxygen Species , Endogenous Metabolite
	Coenzyme Q10 (CoQ10) (ubiquinone) is a naturally occurring compound, acting as the electron carrier in the mitochondrial respiratory chain.
T5A2461	Bufotalin	Bufotaline	Apoptosis , Others , Reactive Oxygen Species
	1. Bufotalin (Bufotaline)e is a kind of poisonous secretions of toads.		Apoptosis , Others , Reactive Oxygen Species
TN1141	Isodeoxyelephantopin		NF-κB , Reactive Oxygen Species , Autophagy
	Isodeoxyelephantopin exerts antitumor effects on several cancer cells by inducing apoptosis , cell cycle arrest , and inhibiting proliferation. It enhances apoptosis and inhibit invasion and osteoclastogenesis by inhibit...		NF-κB , Reactive Oxygen Species , Autophagy
T3S1089	Phillygenin	Epipinoresinol methyl ether,(+)-Phillygenin,Phillygenol,Sylvatesmin,Forsythigenol	Reactive Oxygen Species
	1. Phillyrin, (+)-Phillygenin (Sylvatesmin), and (-)-phillygenin exert the strongest inhibitory activities on NO production with IC(5) values.		Reactive Oxygen Species
T3753	Sinapinic Acid	Sinapic acid,Synapoic acid	Apoptosis , RAAS , Reactive Oxygen Species , HDAC
	Sinapinic Acid (Synapoic acid) protects the rat liver from CCl4-induced inflammation, most likely by acting as a free radical scavenger and modulator of NF-κB p65 activation and proinflammatory cytokine expression. Sinap...		Apoptosis , RAAS , Reactive Oxygen Species , HDAC
T0928	L-Ascorbic acid	Vitamin C,Ascorbic acid,L(+)-Ascorbic acid,L-Ascorbate	Apoptosis , Calcium Channel , Reactive Oxygen Species , Endogenous Metabolite
	L-Ascorbic acid (Vitamin C) is a natural product that is a potent reducing agent and antioxidant. L-Ascorbic acid functions in fighting bacterial infections, in detoxifying reactions, and in the formation of collagen. L-...
T8693	Diallyl Trisulfide		Apoptosis , Reactive Oxygen Species , Antifungal
	Diallyl Trisulfide is an organic polysulfide compound found in garlic that acts as an H2S donor.		Apoptosis , Reactive Oxygen Species , Antifungal
T3785	11-oxo-mogroside V	11-oxo Mogroside V	Reactive Oxygen Species
	11-oxo-mogroside V (11-oxo Mogroside V) is a sweet tasting cucurbitane glycoside derivative of mogroside V. It has antioxidant effects against both O2- and OH- and prevents OH-induced DNA damage.		Reactive Oxygen Species
T4S0797	Berberine	Berberin,Umbellatine	Reactive Oxygen Species , Topoisomerase , Endogenous Metabolite , Antibacterial , Antibiotic , Autophagy
	1. Berberine (Umbellatine) is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism. 2. Berberine may as a broad-spectrum anti-microbial medicine, a complementary therapeutic agent for HIV/AIDS. 3....
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Natural Products

Glucoraphanin

TQ0212

Synonym:

Target: Antioxidant, Reactive Oxygen Species

Echinacoside

T1716

Synonym:

Target: Reactive Oxygen Species, Wnt/beta-catenin

Octahydrocurcumin

T3S1692

Synonym:

Target: Anti-infection, NF-κB, Reactive Oxygen Species, ROS

Arjunolic acid

TN1403

Synonym:

Target: IL Receptor, TNF, Reactive Oxygen Species, JNK, AChE

Hexahydrocurcumin

TQ0288

Synonym:

Target: Reactive Oxygen Species, ROS, COX

Riboflavin Tetrabutyrate

T16747

Synonym:

Target: Reactive Oxygen Species

Ziyuglycoside II

T6S2038

Synonym:

Target: Apoptosis, Antioxidant, Reactive Oxygen Species

Psoralidin

T3399

Synonym:

Target: Others, Estrogen/progestogen Receptor, Reactive Oxygen Species, Lipoxygenase, Gamma-secretase, Akt, COX, Antibacterial

Echinocystic acid

T2866

Synonym:

Target: Apoptosis, Antioxidant, Reactive Oxygen Species

Methyl Vanillate

T2818

Synonym:

Target: Reactive Oxygen Species, Wnt/beta-catenin, Endogenous Metabolite

Rutaevin

TN2167

Synonym:

Target: Reactive Oxygen Species, NO Synthase

Sodium Thiocyanate

T8033

Synonym:

Target: Others, Reactive Oxygen Species, Interleukin

norbergenin

T9057

Synonym:

Target: IL Receptor, TNF, Reactive Oxygen Species

Pelargonidin chloride

TN1058

Synonym:

Target: NOS, Reactive Oxygen Species, Nrf2, NO Synthase

Camalexin

T10668

Synonym:

Target: Reactive Oxygen Species, ROS, Antibacterial, Antifungal

Garcinone D

TN1674

Synonym:

Target: Reactive Oxygen Species, Nrf2, STAT

Uric Acid

T0626

Synonym: 2,6,8-Trioxopurine,2,6,8-Trioxypurine,2,6,8-Trihydroxypurine,Lithic acid,Urate

Target: Reactive Oxygen Species, Endogenous Metabolite, Phosphorylase

Bigelovin

TN6735

Synonym:

Target: Apoptosis, Reactive Oxygen Species, Retinoid Receptor, Autophagy, RAR/RXR

3,5-Di-tert-butylphenol

T36735

Synonym:

Target: Reactive Oxygen Species, Antifungal

Rifamycin S

T8347

Synonym:

Target: Reactive Oxygen Species, ROS, Antibacterial, Antibiotic

Isotrifoliin

T4902

Synonym: Isoquercetin,Isoquercitroside

Target: Reactive Oxygen Species

Isosteviol

T3332

Synonym: (-)-Isosteviol

Target: IL Receptor, Potassium Channel, TNF, NF-κB, Reactive Oxygen Species, COX, Topoisomerase

Aureusidin

TN5634

Synonym: Auresudidin,Auresidin

Target: Antioxidant, Reactive Oxygen Species, Lipoxygenase

Ellagic acid

T0465

Synonym: Gallogen,Elagostasine

Target: Hedgehog/Smoothened, Casein Kinase, Reactive Oxygen Species, Topoisomerase, Endogenous Metabolite, PKA, Syk, PKC, Carbonic Anhydrase

Quercetin

T2174

Synonym: Sophoretin

Target: Apoptosis, Mitophagy, Reactive Oxygen Species, PI3K, Autophagy

Furanodiene

TN1651

Synonym:

Target: Apoptosis, PARP, Reactive Oxygen Species, Caspase, CDK, P-gp

Isobavachalcone

T3861

Synonym: Corylifolinin,Isobacachalcone

Target: Apoptosis, Others, Reactive Oxygen Species, Akt, Autophagy

Lycopene

T2864

Synonym: ψ,ψ-Carotene

Target: Reactive Oxygen Species, ROS

Nobiletin

T2834

Synonym: Hexamethoxyflavone

Target: Apoptosis, MMP, Reactive Oxygen Species, ROR, Autophagy

Piperlongumine

T6947

Synonym: PPLGM,Piplartine

Target: Apoptosis, ERK, Ferroptosis, Reactive Oxygen Species, ROS, Antibacterial, Autophagy

Albiflorin

T6S1653

Synonym: Alibiflorin

Target: Reactive Oxygen Species

Synonym: Macleyine,Hypercorine,Corydinine,Biflorine,Fumarine

Target: Reactive Oxygen Species, Platelet aggregation, Histamine Receptor

S-Methyl-L-cysteine

T8072

Synonym: S-Methylcysteine

Target: Antioxidant, Reactive Oxygen Species

Doxofylline

T0480

Synonym: Doxophylline

Target: PDE, Adenosine Receptor

Citronellol

T3240

Synonym: dihydrogeraniol,(±)-β-Citronellol

Target: Reactive Oxygen Species

Veratric acid

T3744

Synonym: Veratrumenoic acid,3,4-Dimethoxybenzoic acid

Target: Reactive Oxygen Species, COX

Canthaxanthin

T5852

Synonym: all-trans-Canthaxanthin,E 161g

Target: Reactive Oxygen Species

Reynoutrin

T7781

Synonym: Reinutrin,Quercetin-3-D-xyloside

Target: Reactive Oxygen Species

Pinocembrin

T2992

Synonym: 5,7-Dihydroxyflavanone,Dihydrochrysin,Galangin flavanone

Target: NF-κB, Reactive Oxygen Species, Antibacterial, Autophagy

Coenzyme Q10

T2796

Synonym: Ubiquinone-10,CoQ10

Target: Ferroptosis, Reactive Oxygen Species, Endogenous Metabolite

Bufotalin

T5A2461

Synonym: Bufotaline

Target: Apoptosis, Others, Reactive Oxygen Species

Isodeoxyelephantopin

TN1141

Synonym:

Target: NF-κB, Reactive Oxygen Species, Autophagy

Phillygenin

T3S1089

Synonym: Epipinoresinol methyl ether,(+)-Phillygenin,Phillygenol,Sylvatesmin,Forsythigenol

Target: Reactive Oxygen Species

Sinapinic Acid

T3753

Synonym: Sinapic acid,Synapoic acid

Target: Apoptosis, RAAS, Reactive Oxygen Species, HDAC

L-Ascorbic acid

T0928

Synonym: Vitamin C,Ascorbic acid,L(+)-Ascorbic acid,L-Ascorbate

Target: Apoptosis, Calcium Channel, Reactive Oxygen Species, Endogenous Metabolite

Diallyl Trisulfide

T8693

Synonym:

Target: Apoptosis, Reactive Oxygen Species, Antifungal

11-oxo-mogroside V

T3785

Synonym: 11-oxo Mogroside V

Target: Reactive Oxygen Species

Berberine

T4S0797

Synonym: Berberin,Umbellatine

Target: Reactive Oxygen Species, Topoisomerase, Endogenous Metabolite, Antibacterial, Antibiotic, Autophagy

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Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-03462	15 Lipoxygenase 2 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	ALOX15B is a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. ALOX15B converts arachidonic acid exclusively to 15S-hydroperoxy...
TMPY-03553	15 Lipoxygenase 2 Protein, Human, Recombinant	Human	Baculovirus-Insect Cells
	ALOX15B is a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. ALOX15B converts arachidonic acid exclusively to 15S-hydroperoxy...
TMPH-00026	Catechol 1,2-dioxygenase Protein, Acinetobacter baylyi, Recombinant (His)	Actinia equina	E. coli
	Pore-forming protein that forms cations-selective hydrophilic pores of around 1 nm and causes cardiac stimulation and hemolysis. Pore formation is a multi-step process that involves specific recognition of membrane sphin...
TMPY-01883	EPOR Protein, Human, Recombinant (His)	Human	HEK293
	Erythropoietin (EPO) is the major glycoprotein hormone regulator of mammalian erythropoiesis, and is produced by kidney and liver in an oxygen-dependent manner. The biological effects of EPO are mediated by the specific ...
TMPY-02481	ACOX1 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Peroxisomal acyl-coenzyme A oxidase 1(ACOX1 or AOX) is the first enzyme of the fatty acid beta-oxidation pathway and belongs to the Acyl-CoA oxidase family. Human liver peroxisomes contain two acyl-CoA oxidases, namely, ...
TMPY-03945	Latent TGF beta 1 Protein, Rat, Recombinant (His)	Rat	HEK293
	TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-04211	Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-00608	TGF beta 1 Protein, Rat/Mouse, Recombinant	Mouse,Rat	HEK293
	TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-02638	TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant	Human,Rhesus,Cynomolgus,Canine	CHO
	TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-01133	Latent TGF beta 1 Protein, Human, Recombinant (His)	Human	HEK293
	TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-00500	Latent TGF beta 1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPH-01318	SOD3 Protein, Human, Recombinant	Human	E. coli
	Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen.
TMPH-01317	SOD3 Protein, Human, Recombinant (His)	Human	E. coli
	Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen.
TMPJ-00753	Myoglobin Protein, Human, Recombinant (His)	Human	E. coli
	Myoglobin(MB) is a cytoplasmic protein expressed in myocytes of the heart and skeletal muscle that reversibly binds oxygen. It belongs to the globin family. Functions of myoglobin include oxygen storage and transport, as...
TMPH-00396	TrhO Protein, Chlamydophila felis, Recombinant (His)	Chlamydia felis	E. coli
	Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
TMPH-00772	Leghemoglobin C2 Protein, Glycine max, Recombinant (His)	Glycine max	E. coli
	Provides oxygen to the bacteroids. This role is essential for symbiotic nitrogen fixation.
TMPH-03134	Leghemoglobin Lb120-8 Protein, Pisum sativum, Recombinant (His)	Pisum sativum	E. coli
	Provides oxygen to the bacteroids. This role is essential for symbiotic nitrogen fixation.
TMPJ-01248	Cytoglobin/CYGB Protein, Human, Recombinant (His)	Human	E. coli
	Cytoglobin is a ubiquitously globin protein that belongs to the globin family. The highest expressed in heart, stomach, bladder and small intestine. CYGB acts a protector under conditions of oxidative stress. CYGB may be...
TMPH-03092	Leghemoglobin A Protein, Phaseolus vulgaris, Recombinant (His & Myc)	Phaseolus vulgaris	E. coli
	Provides oxygen to the bacteroids. This role is essential for symbiotic nitrogen fixation.
TMPH-00575	GlpD Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses molecular oxygen or nitrate as electron acceptor.
TMPH-02141	CYP21A2 Protein, Human, Recombinant (His)	Human	Yeast
	A cytochrome P450 monooxygenase that plays a major role in adrenal steroidogenesis. Catalyzes the hydroxylation at C-21 of progesterone and 17alpha-hydroxyprogesterone to respectively form 11-deoxycorticosterone and 11-d...
TMPH-01761	Neuroglobin Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhi...
TMPH-02618	CYP2E1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electr...
TMPH-02140	CYP21A2 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	A cytochrome P450 monooxygenase that plays a major role in adrenal steroidogenesis. Catalyzes the hydroxylation at C-21 of progesterone and 17alpha-hydroxyprogesterone to respectively form 11-deoxycorticosterone and 11-d...
TMPJ-00800	BPGM Protein, Human, Recombinant (His)	Human	E. coli
	Bisphosphoglycerate Mutase (BPGM) is a member of the Phosphoglycerate Mutase family and BPG-Dependent PGAM subfamily. BPGM is a multifunctional enzyme. BPGM catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,...
TMPH-02198	TXNRD2 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Involved in the control of reactive oxygen species levels and the regulation of mitochondrial redox homeostasis. Maintains thioredoxin in a reduced state. May play a role in redox-regulated cell signaling.
TMPH-03275	Cytoglobin Protein, Rat, Recombinant (His & Myc)	Rat	E. coli
	May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer. Plays a role in the development of liver fibrosis. Has a peroxidase activity.
TMPH-01084	CYP11A1 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholester...
TMPH-02617	COX5A Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase...
TMPH-00099	NDK1 Protein, Arabidopsis thaliana, Recombinant (His & Myc)	Arabidopsis thaliana	Yeast
	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Plays a...
TMPJ-01274	ERO1L Protein, Human, Recombinant (His)	Human	Human Cells
	ERO1-Like Protein α (ERO1L) is an enzyme that belongs to the EROs family. ERO1L is expressed at high level in esophagus and upper digestive tract. ERO1L is an essential oxidoreductase that oxidizes proteins in the endopl...
TMPH-02233	P4HTM Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic...
TMPK-00571	OSMR Protein, Canine, Recombinant (His)	Canine	HEK293
	OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and prom...
TMPH-01745	NOX4 Protein, Human, Recombinant (Cell-Free, His)	Human	in vitro E. coli expression system
	Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor...
TMPK-00493	OSMR Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and prom...
TMPH-01746	NOX4 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor...
TMPH-01280	EGLN1 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of th...
TMPH-02875	ROMO1 Protein, Mouse, Recombinant (His)	Mouse	in vitro E. coli expression system
	Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.; Induces production of reactive oxygen species (ROS) which are n...
TMPH-02106	SH3PXD2A Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides...
TMPH-02139	CYP17A1 Protein, Human, Recombinant (GST)	Human	E. coli
	A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen sy...
TMPH-02104	Sestrin-3/SESN3 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway. May also regulate the insulin-receptor signaling pathway through activation of TORC2. This metabolic regulator may al...
TMPH-03751	CYBB Protein, Human, Recombinant (His)	Human	E. coli
	Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membr...
TMPY-02044	SOD2 Protein, Human, Recombinant	Human	E. coli
	Superoxide dismutases (SOD) are important anti-oxidant enzymes that guard against superoxide toxicity. In humans, as in all mammals and most chordates, three forms of superoxide dismutase (SOD) are present: SOD1 is locat...
TMPH-01080	Ceruloplasmin Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the ...
TMPH-00577	AlkB Protein, E. coli, Recombinant (His & Myc & SUMO)	E. coli	E. coli
	Dioxygenase that repairs alkylated DNA and RNA containing 3-methylcytosine or 1-methyladenine by oxidative demethylation. Has highest activity towards 3-methylcytosine. Has lower activity towards alkylated DNA containing...
TMPH-00359	AlkB Protein, Caulobacter vibrioides, Recombinant (His & Myc)	Caulobacter vibrioides	E. coli
	Dioxygenase that repairs alkylated DNA and RNA containing 3-methylcytosine or 1-methyladenine by oxidative demethylation. Has highest activity towards 3-methylcytosine. Has lower activity towards alkylated DNA containing...
TMPH-02470	PDK3 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Inhibits pyruvate dehydrogenase activity by phosphorylation of the E1 subunit PDHA1, and thereby regulates glucose metabolism and aerobic respiration. Can also phosphorylate PDHA2. Decreases glucose utilization and incre...
TMPY-01577	ORP150 Protein, Human, Recombinant (His)	Human	HEK293
	Hypoxia up-regulated protein 1, also known as 15 kDa oxygen-regulated protein, 17 kDa glucose-regulated protein, ORP-15, GRP-17, and HYOU1, is a member of the heat shock protein 7 family. Seven members from four differen...
TMPJ-00946	TALDO1 Protein, Human, Recombinant (His)	Human	Human Cells
	Transaldolase (TALDO1) belongs to the transaldolase family of Type 1 subfamily. TALDO1 is expressed selectively in oligodendrocytes of the brain. TALDO1 is a key enzyme of the nonoxidative pentose phosphate pathway provi...
TMPJ-00105	SOD2 Protein, Human, Recombinant (His)	Human	Human Cells
	Superoxide Dismutase (SOD2) belongs to the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial matrix protein that forms a homotetramer and binds one manganese ion per subunit. SOD2 transforms toxic super...
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15 Lipoxygenase 2 Protein, Human, Recombinant (His & GST)

TMPY-03462

Species: Human

Expression System: Baculovirus-Insect Cells

15 Lipoxygenase 2 Protein, Human, Recombinant

TMPY-03553

Species: Human

Expression System: Baculovirus-Insect Cells

Catechol 1,2-dioxygenase Protein, Acinetobacter baylyi, Recombinant (His)

TMPH-00026

Species: Actinia equina

Expression System: E. coli

EPOR Protein, Human, Recombinant (His)

TMPY-01883

Species: Human

Expression System: HEK293

ACOX1 Protein, Human, Recombinant (His)

TMPY-02481

Species: Human

Expression System: Baculovirus-Insect Cells

Latent TGF beta 1 Protein, Rat, Recombinant (His)

TMPY-03945

Species: Rat

Expression System: HEK293

Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His)

TMPY-04211

Species: Cynomolgus

Expression System: HEK293

TGF beta 1 Protein, Rat/Mouse, Recombinant

TMPY-00608

Species: Mouse,Rat

Expression System: HEK293

TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant

TMPY-02638

Species: Human,Rhesus,Cynomolgus,Canine

Expression System: CHO

Latent TGF beta 1 Protein, Human, Recombinant (His)

TMPY-01133

Species: Human

Expression System: HEK293

Latent TGF beta 1 Protein, Mouse, Recombinant (His)

TMPY-00500

Species: Mouse

Expression System: HEK293

SOD3 Protein, Human, Recombinant

TMPH-01318

Species: Human

Expression System: E. coli

SOD3 Protein, Human, Recombinant (His)

TMPH-01317

Species: Human

Expression System: E. coli

Myoglobin Protein, Human, Recombinant (His)

TMPJ-00753

Species: Human

Expression System: E. coli

TrhO Protein, Chlamydophila felis, Recombinant (His)

TMPH-00396

Species: Chlamydia felis

Expression System: E. coli

Leghemoglobin C2 Protein, Glycine max, Recombinant (His)

TMPH-00772

Species: Glycine max

Expression System: E. coli

Leghemoglobin Lb120-8 Protein, Pisum sativum, Recombinant (His)

TMPH-03134

Species: Pisum sativum

Expression System: E. coli

Cytoglobin/CYGB Protein, Human, Recombinant (His)

TMPJ-01248

Species: Human

Expression System: E. coli

Leghemoglobin A Protein, Phaseolus vulgaris, Recombinant (His & Myc)

TMPH-03092

Species: Phaseolus vulgaris

Expression System: E. coli

GlpD Protein, E. coli, Recombinant (His)

TMPH-00575

Species: E. coli

Expression System: E. coli

CYP21A2 Protein, Human, Recombinant (His)

TMPH-02141

Species: Human

Expression System: Yeast

Neuroglobin Protein, Human, Recombinant (His & SUMO)

TMPH-01761

Species: Human

Expression System: E. coli

CYP2E1 Protein, Mouse, Recombinant (His)

TMPH-02618

Species: Mouse

Expression System: E. coli

CYP21A2 Protein, Human, Recombinant (E. coli, His)

TMPH-02140

Species: Human

Expression System: E. coli

BPGM Protein, Human, Recombinant (His)

TMPJ-00800

Species: Human

Expression System: E. coli

TXNRD2 Protein, Human, Recombinant (His & SUMO)

TMPH-02198

Species: Human

Expression System: E. coli

Cytoglobin Protein, Rat, Recombinant (His & Myc)

TMPH-03275

Species: Rat

Expression System: E. coli

CYP11A1 Protein, Human, Recombinant (His & SUMO)

TMPH-01084

Species: Human

Expression System: E. coli

COX5A Protein, Mouse, Recombinant (His & SUMO)

TMPH-02617

Species: Mouse

Expression System: E. coli

NDK1 Protein, Arabidopsis thaliana, Recombinant (His & Myc)

TMPH-00099

Species: Arabidopsis thaliana

Expression System: Yeast

ERO1L Protein, Human, Recombinant (His)

TMPJ-01274

Species: Human

Expression System: Human Cells

P4HTM Protein, Human, Recombinant (His & SUMO)

TMPH-02233

Species: Human

Expression System: E. coli

OSMR Protein, Canine, Recombinant (His)

TMPK-00571

Species: Canine

Expression System: HEK293

NOX4 Protein, Human, Recombinant (Cell-Free, His)

TMPH-01745

Species: Human

Expression System: in vitro E. coli expression system

OSMR Protein, Cynomolgus, Recombinant (His)

TMPK-00493

Species: Cynomolgus

Expression System: HEK293

NOX4 Protein, Human, Recombinant (E. coli, His)

TMPH-01746

Species: Human

Expression System: E. coli

EGLN1 Protein, Human, Recombinant (His & Myc)

TMPH-01280

Species: Human

Expression System: E. coli

ROMO1 Protein, Mouse, Recombinant (His)

TMPH-02875

Species: Mouse

Expression System: in vitro E. coli expression system

SH3PXD2A Protein, Human, Recombinant (His & Myc)

TMPH-02106

Species: Human

Expression System: E. coli

CYP17A1 Protein, Human, Recombinant (GST)

TMPH-02139

Species: Human

Expression System: E. coli

Sestrin-3/SESN3 Protein, Human, Recombinant (His & Myc)

TMPH-02104

Species: Human

Expression System: E. coli

CYBB Protein, Human, Recombinant (His)

TMPH-03751

Species: Human

Expression System: E. coli

SOD2 Protein, Human, Recombinant

TMPY-02044

Species: Human

Expression System: E. coli

Ceruloplasmin Protein, Human, Recombinant (His & Myc)

TMPH-01080

Species: Human

Expression System: E. coli

AlkB Protein, E. coli, Recombinant (His & Myc & SUMO)

TMPH-00577

Species: E. coli

Expression System: E. coli

AlkB Protein, Caulobacter vibrioides, Recombinant (His & Myc)

TMPH-00359

Species: Caulobacter vibrioides

Expression System: E. coli

PDK3 Protein, Mouse, Recombinant (His)

TMPH-02470

Species: Mouse

Expression System: E. coli

ORP150 Protein, Human, Recombinant (His)

TMPY-01577

Species: Human

Expression System: HEK293

TALDO1 Protein, Human, Recombinant (His)

TMPJ-00946

Species: Human

Expression System: Human Cells

SOD2 Protein, Human, Recombinant (His)

TMPJ-00105

Species: Human

Expression System: Human Cells

--------- More ---------

Cat No.	Product Name
L2910	Antioxidant Compound Library	1330 compounds
	Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species (ROS) and a biological system's ability to readily detoxify the reactive intermediates or repair the resulting damage. ...
L2150	Anti-Cancer Drug Library	3159 compounds
	A unique collection of 3159 anticancer drugs for high throughput screening (HTS) and high content screening (HCS);
L2160	Anti-Cancer Active Compound Library	3250 compounds
	A unique collection of 3250 compounds with known anti-cancer activity for high throughput screening (HTS) and high content screening (HCS);
L2521	Glycolysis Compound Library	560 compounds
	560 glycolysis-related active compounds for high-throughput and high-content screening.
L2120	Anti-Cancer Clinical Compound Library	2614 compounds
	A unique collection of 2614 anti-cancer compounds for high throughput screening (HTS) and high content screening (HCS);
L2100	Anti-Cancer Compound Library	7360 compounds
	A unique collection of 7360 compounds with anti-cancer activity for high throughput screening (HTS) and high content screening (HCS);
L4800	Angiogenesis related Compound Library	1370 compounds
	A unique collection of 1370 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high throughput screening (HTS) and high content screening (HCS);
L2110	Anti-Cancer Approved Drug Library	1825 compounds
	A unique collection of 1825 approved anti-cancer drugs for high throughput screening (HTS) and high content screening (HCS);
L2180	Anti-Cancer Compound Library Plus	1468 compounds
	Well-chosen 1468 anti-tumor compounds with unique structures;
L1300	PI3K-AKT-mTOR Compound Library	425 compounds
	A unique collection of 425 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with PI3K/Akt/mTOR signaling;
L5300	Mitochondria-Targeted Compound Library	830 compounds
	A unique collection of 830 promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine;
L8500	HIF-1 Signaling Pathway Compound Library	1352 compounds
	A unique collection of 1352 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies；