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Cat No. | Product Name | Synonyms | Targets |
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T21700 | NOS-IN-1 | 2-Imino-4-methylpiperidine (acetate) | NOS |
NOS-IN-1 (2-Imino-4-methylpiperidine acetate) is a potent and orally active inhibitor of NO synthase (NOS) isoforms. NOS-IN-1 exhibits IC50s of 0.1 μM, 0.2 μM, and 1.1μM for human iNOS (hiNOS), hnNOS and heNOS, respectiv... | |||
T14286 | ANB-NOS | Others | |
ANB-NOS is a alkyl/ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system w... | |||
T73353 | NOS-IN-3 | ||
NOS-IN-3 is a potent, selective, imidamide derived NOS inhibitor with an IC 50 against iNOS of 4.6 µM, without inhibiting eNOS . NOS-IN-3 has little toxicity and can be studied in the treatment of inducible isoform invo... | |||
T61426 | NOS-IN-2 | ||
NOS-IN-2 (Compound 4i), an imidamide-derived NOS inhibitor, exhibits high potency and selectivity, specifically inhibiting iNOS with an IC50 of 20 μM while sparing eNOS. Demonstrating minimal toxicity, it is suitable for... | |||
T7474 | 7-Nitroindazole | NOS | |
7-Nitroindazole is a non-selective inhibitor of NOS isoforms in vitro for neuronal nitric oxide synthase showing a 10-fold selectivity for neuronal NOS. | |||
T10107 | 3-Bromo-7-nitroindazole | NOS | |
3-Bromo-7-nitroindazole is a more potent and selective inhibitor of neuronal nitric oxide synthase (nNOS) than eNOS or iNOS. It affects the intercellular messenger NO synthesis throughout the brain and body. | |||
T1322 | Bendazol | Dibazol,Dibazole | Dopamine Receptor , NO Synthase |
Bendazol (Dibazol) is always used as the drug for hypertension and cerebral Angiospasm. | |||
T37696 | NOS1-IN-1 | nNOS Inhibitor I | NOS |
NOS1-IN-1(nNOS Inhibitor I) is a potent, selective and cell permeable nNOS inhibitor (Ki: 120 nM).NOS1-IN-1 has a Ki value of 39 μM for eNOS and 325 μM for iNOS.NOS1-IN-1 can be used for the study of neurological disorde... | |||
T22724 | Dimaprit dihydrochloride | NOS , NO Synthase , Histamine Receptor | |
Dimaprit dihydrochloride is a selective histamine H2 receptor agonist. Dimaprit dihydrochloride also inhibits nNOS with an IC50 of 49 μM. It can stimulate gastric acid secretion. | |||
T15697 | L-NMMA acetate | Tilarginine acetate,Methylarginine acetate | NOS |
L-NMMA acetate (Tilarginine acetate) is an inhibitor of nitric oxide synthase of all NOS isoforms (i.e. NOS1, NOS2, and NOS3). The Ki values are 0.18, 0.4, and 6 µM for nNOS, eNOS, and iNOS, respectively. | |||
T19853 | Dimethoxycurcumin | Veratrylcurcuminoid | Others |
Dimethoxycurcumin (Veratrylcurcuminoid) is an analog of curcumin with more metabolical stability. Dimethoxycurcumin induces epigenetic changes in leukemia cells and the expression of promoter methylated genes. | |||
T21507 | 7-Ethoxyresorufin | Resorufin ethyl ether | P450 , NO Synthase |
7-Ethoxyresorufin (Resorufin ethyl ether) (7-ER) is a fluorometric substrate for and competitive inhibitor of cytochrome P450, especially CYP1A1. | |||
T2334 | Avanafil | TA1790 | PDE |
Avanafil (TA1790) is a selective inhibitor of phosphodiesterase type 5 (PDE5) and is used as therapy of erectile dysfunction. | |||
T7461 | 2,4-Diamino-6-hydroxypyrimidine | DAHP | Reactive Oxygen Species , NO Synthase |
2,4-Diamino-6-hydroxypyrimidine (DAHP) (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis | |||
T3491 | 1400W dihydrochloride | 1400W 2HCl,N-(3-(Aminomethyl)benzyl)acetamidine | NOS , NO Synthase |
1400W dihydrochloride (N-(3-(Aminomethyl)benzyl)acetamidine) is a highly effective and specific inhibitor of inducible NOS2 (iNOS). | |||
T12808 | S-Nitroso-N-acetyl-DL-penicillamine | SNAP | NO Synthase |
S-Nitroso-N-acetyl-DL-penicillamine (SNAP) acts as a stable inhibitor of platelet aggregation, is a nitric oxide donor and . | |||
T19916 | TRIM | 1-(2-Trifluoromethylphenyl)imidazole | NOS |
TRIM (1-(2-Trifluoromethylphenyl)imidazole) is an inhibitor of nNOS. | |||
T7206L | 2-Iminobiotin hydrobromide | Guanidinobiotin | NOS , NO Synthase |
2-Iminobiotin hydrobromide (Guanidinobiotin) is a cyclic guanidino analog of biotin that acts as a reversible inhibitor of inducible nitric oxide synthase (iNOS) and neuronal NOS (nNOS; Ki of 21.8 and 37.5 μM for mouse i... | |||
T1479 | Isosorbide dinitrate | Isordil,Nitrosorbide,Sorbide nitrate,Sorbidnitrate | Others , NO Synthase |
Isosorbide dinitrate (Isordil) is a vasodilator used in the treatment of angina pectoris. | |||
T3198L | PRE-084 hydrochloride | Sigma receptor | |
PRE-084 hydrochloride is a selective agonist of σ1(IC50:44 nM, in the sigma receptor assay). | |||
T1102 | Mifepristone | C-1073,RU486,RU 38486 | Glucocorticoid Receptor , Estrogen/progestogen Receptor , Progesterone Receptor , NO Synthase , Autophagy |
Mifepristone (C-1073) is a Progestin Antagonist. The mechanism of action of mifepristone is as a Progestational Hormone Receptor Antagonist. | |||
T22419 | S-Methylisothiourea sulfate | (S)-Methylisothiourea sulfate | NOS , NO Synthase , HSV |
S-Methylisothiourea sulfate ((S)-Methylisothiourea sulfate) is a potent and selective inhibitor of iNOS and exerts beneficial effects in rodent models of septic shock[1]. | |||
T6888 | Methylene Blue | methylthioninium chloride,CI-52015,Tetramethylthionine chloride,Basic Blue 9 | Guanylate cyclase , Microtubule Associated , NO Synthase , Parasite , Monoamine Oxidase |
Methylene Blue (Tetramethylthionine chloride) (IC50 of 1.9 μM) inhibits tau filament formation. And it inhibits soluble guanylyl cyclase. It is also used as a dye in chromoendoscopy. | |||
T3211 | Midostaurin | N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251 | Others , PKC |
PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platel... | |||
T0006 | Methylene Blue trihydrate | Methylthionine chloride,Basic blue 9,Methylene Blue | Guanylate cyclase , Microtubule Associated , NO Synthase , Parasite , Monoamine Oxidase |
Methylene Blue trihydrate (Basic blue 9) is a compound consisting of dark green crystals or crystalline powder, having a bronze-like luster. Solutions in water or alcohol have a deep blue color. Methylene Blue trihydrate... | |||
T6570 | L-NAME hydrochloride | L-NAME HCl,N(G)-Nitro-L-arginine methyl ester,NG-Nitroarginine methyl ester hydrochloride | NOS , NO Synthase |
L-NAME hydrochloride (L-NAME HCl), a cell-permeable NO synthase inhibitor, displays Ki values of 4.4 μM, 15 nM, and 39 nM, for iNOS (mouse) , nNOS (bovine) , and eNOS (human), respectively. | |||
T0358 | Aminoguanidine hydrochloride | Imino semicarbazide,Pimagedine hydrochloride,CP-12009-18 tartrate,Hydrazinecarboximidamide,Guanyl hydrazine,Pimagedine | NOS , NO Synthase |
Aminoguanidine hydrochloride (Hydrazinecarboximidamide) is a diamine oxidase and NO synthase inhibitor, used in the treatment of diabetic nephropathy. | |||
T9537 | N'-Nitro-D-arginine | N'-Nitro-D-arginine,H-D-Arg(NO2)-OH,(R)-2-Amino-5-(3-nitroguanidino)pentanoic acid | Others |
N'-Nitro-D-arginine (N'-Nitro-D-arginine) is a Building Block. | |||
T7206 | 2-Iminobiotin | 2-IMINOBIOTIN HYDROBROMIDE,Guanidinobiotin | NOS , NO Synthase |
2-Iminobiotin (Guanidinobiotin) is a cyclic guanidino analog of biotin that acts as a reversible inhibitor of inducible nitric oxide synthase (iNOS) and neuronal NOS (nNOS; Ki of 21.8 and 37.5 μM for mouse iNOS and rat n... | |||
T83625 | INOS-IN-14 | 3-bromo-1H-indazole-7-carbonitrile | NOS |
iNOS-IN-14 (3-bromo-1H-indazole-7-carbonitrile) is a potent nitric oxide synthase (NOS) inhibitor that inhibits the NADPH oxidase activity of nNOS. | |||
T22438 | Tetramethylthiuram monosulfide | TMTM | Others |
Tetramethylthiuram monosulfide is widely used as a catalyst in rubber-processing techniques, it possesses a medium-degree toxicity and causes point mutations in strains TA 100 and TA 1535 (Salmonella typhimurium LT 2). | |||
T32826 | LNA-Adenosine | LNA-A,LNA Adenosine,2'-O,4'-C-Methyleneadenosine | Nucleoside Antimetabolite/Analog |
LNA-Adenosine (LNA-A) is a nucleoside analogue that acts as a ligand for adenosine A3 receptors. | |||
T1296 | 4-Aminosalicylic acid | Aminosalicylic acid,4-aminosalicylate,para-aminosalicylic acid,Aminopar | NF-κB , Lipoxygenase , COX , Glutathione Peroxidase , Antibacterial , Antibiotic |
4-Aminosalicylic acid (para-aminosalicylic acid) is an analog of para-aminobenzoic acid (PABA) with antitubercular activity. | |||
T16263 | N6-Cyclopentyladenosine | UK-80882,CPA | Adenosine Receptor |
N6-Cyclopentyladenosine (CPA) is a selective agonist of the adenosine A1 receptor and can be used to mimic the action of the adenosine A1 receptor, with Ki's of 2.3 nM, 790 nM, and 43 nM for human A1, A2A, and A3 recepto... | |||
TNU0352 | 1-beta-D-Arabinofuranosylthymine | Thymine 1-β-D-arabinofuranoside,Spongothymidine | Apoptosis |
1-beta-D-Arabinofuranosylthymine (Thymine 1-β-D-arabinofuranoside) is a purine nucleoside analog. Purine nucleoside analogs have a broad spectrum of antitumor activity, targeting inert lymphoid malignancies and inducing ... | |||
TP1088 | N-Acetylcarnosine | N-Acetyl-L-carnosine | Others |
N-Acetylcarnosine (N-Acetyl-L-carnosine) is thought to be able to combat some of the effects of oxidative stress as it has anti-oxidant properties. | |||
T2671 | Regadenoson | CVT-3146,Lexiscan | Adenosine Receptor |
Regadenoson (CVT-3146) is an adenosine derivative and selective A2A adenosine receptor agonist with coronary vasodilating activity. Upon administration, regadenoson selectively binds to and activates the A2A adenosine re... | |||
TNU0355 | N6-Methyl-2'-O-methyladenosine | N6,2′-O-Dimethyladenosine | Nucleoside Antimetabolite/Analog |
N6-Methyl-2'-O-methyladenosine (N6,2′-O-Dimethyladenosine), a substrate for adiposity and obesity-related genes (FTO), is a reversible modifier compound found on a wide variety of RNA molecules.N6,2′-O-Dimethyladenosine ... | |||
T37571 | 4-Methylumbelliferyl-β-D-Glucopyranoside | MU-GLU,4-MUG,4-MU-GLU,4-MU-β-Gluc | Others |
4-Methylumbelliferyl-β-D-Glucopyranoside (4-MU-GLU) is used in the GCase activity assay based on the catalytic hydrolysis of 4-methylumbelliferyl β-D-glucopyranoside that releases the highly fluorescent 4-methylumbellife... | |||
T8551 | Nitrobenzylthioinosine | NBMPR | AChR , Adenosine Receptor |
Nitrobenzylthioinosine (NBMPR) is an inhibitor of ENT1 transporter that binds to ENT1 transporter with high affinity. | |||
T3614 | Inosine pranobex | Groprinosin,Isoprinosine,Immunovir,Delimmun | IL Receptor , HIV Protease |
Inosine pranobex (Delimmun) has a number of immunomodulatory effects, including inducing T-lymphocyte differentiation, augmenting macrophage and NK cell functions, and stimulating IL-2 production. Through these effects a... | |||
T18910 | Acid Yellow 9 monosodium salt | Hydrogen 4-aminoazobenzene-3,4'-disulphonate (sodium salt) | Others |
Acid Yellow 9 monosodium salt (Hydrogen 4-aminoazobenzene-3,4'-disulphonate (sodium salt)) is an azo dye, degraded by Pseudomonas fluorescens as a sole source of nitrogen, carbon, and energy for the bacterium. | |||
TNU0085 | 2'-Deoxy-2'-fluoroarabinoadenosine | Nucleoside Antimetabolite/Analog | |
2'-Deoxy-2'-fluoroarabinoadenosine is a nucleoside analogue with extensive anti-tumor activity and can be used for the study of tumor diseases. | |||
T17028 | Tefinostat | CHR-2845 | HDAC |
Tefinostat (CHR-2845) is a potent monocyte/macrophage-targeted histone deacetylase (HDAC) inhibitor. Tefinostat is cleaved to the active acid CHR-2847 by the intracellular esterase human carboxylesterase-1 (hCE-1).Tefino... | |||
T5949 | Dideoxyadenosine | ||
2',3'-Dideoxyadenosine is an inhibitor of HIV replication with antiretroviral activity and antiviral efficacy [1]. | |||
T21620 | Adenosine receptor antagonist 4 | Adenosine Receptor | |
Adenosine receptor antagonist 4 is an adenosine receptor antagonist. | |||
T28748 | Selodenoson | RG14202,DTI0009,DTI-0009,RG-14202,DT-009,DT009 | Adenosine Receptor |
Selodenoson (RG-14202) is a selective adenosine A1 receptor agonist used to slow the heart rate in patients with atrial fibrillation and to treat arrhythmias. | |||
T38236 | 2′-Deoxy-2′-fluoroguanosine | Nucleoside Antimetabolite/Analog , Influenza Virus | |
2′-Deoxy-2′-fluoroguanosine is a nucleoside analog that potently inhibits influenza virus A and B strains(EC90 <0.35 μM). 2'-Deoxy-2'-fluoroguanosine is an inhibitor of influenza virus replication in the upper respirator... | |||
T10111 | 3-Deazaadenosine hydrochloride | Others , HIV Protease | |
3-Deazaadenosine hydrochloride is an inhibitor of S-adenosylhomocysteine hydrolase (Ki: 3.9 µM). It has anti-inflammatory, anti-proliferative, and anti-HIV activity. | |||
T10066 | 2',5'-Dideoxyadenosine | Adenylyl cyclase , Adrenergic Receptor , AChR | |
2',5'-Dideoxyadenosine is a potent and non-competitive adenylyl cyclase inhibitor via binding the P-site (IC50: 3 μM). |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6S2023 | Harpagoside | Others , COX , NO Synthase | |
1. Harpagoside has anti-inflammatory activity. 2. Harpagoside at 3 mM concentration, shows moderate inhibition of seed germination. 3. Harpagoside can inhibit lipopolysaccharide-induced mRNA levels and protein expression... | |||
TQ0301 | Kuwanon A | NO Synthase | |
Kuwanon A inhibits nitric oxide production (IC50: 10.5 μM). Kuwanon A is a flavone derivative isolated from Morus alba L. | |||
T2S0765 | Epibetulinic acid | NO Synthase , Prostaglandin Receptor | |
Epibetulinic acid has anti-inflammatory activity, it exhibits potent inhibitory effects on NO and prostaglandin E(2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin. | |||
T6S1665 | Irisflorentin | Others , NO Synthase | |
1. Irisflorentin blocks apoptosis pathways, by exerting its effects by promoting rpn-3 expression to enhance the activity of proteasomes and down-regulating egl-1 expression. 2. Irisflorentin has anti-inflammatory mechan... | |||
T7682 | Asymmetric dimethylarginine | Endogenous Metabolite , NO Synthase , NOD | |
Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS) | |||
T5S0285 | Cistanoside A | Others | |
1. Cistanoside A possesses protective activities on CCl4 induced hepatotoxicity in mice, which is involved with increasing free radicals clearing activities, alleviating lipid-overoxidation damage, and improving respirat... | |||
T3847 | Asperuloside | Asperulosid | Others , NO Synthase |
Asperuloside (Asperulosid) has anti-inflammatory activity. | |||
T5838 | L-Canavanine sulfate | NO Synthase , NOD | |
L-Canavanine sulfate is a selective inducible NO synthase inhibitor. | |||
T2791 | Pectolinarin | Apoptosis , Others , NO Synthase , Prostaglandin Receptor , Interleukin | |
Pectolinarin is a Cirsium isolate with anti-inflammatory activity. | |||
T7597 | 6-Biopterin | L-Biopterin | Endogenous Metabolite , NO Synthase , NOD |
6-Biopterin (L-Biopterin) is a natural product,is a NO synthase cofactor. | |||
T4808 | Agmatine sulfate | Agmatine sulfate salt | Endogenous Metabolite , NO Synthase , Imidazoline Receptor |
Agmatine sulfate (Agmatine sulfate salt) is a bioactive metabolite of the arginine amino acid. It exerts modulatory action at multiple molecular targets, such as neurotransmitter systems, ion channels and nitric oxide sy... | |||
TN2139 | Regaloside B | NOS , COX , NO Synthase | |
Regaloside B, a phenylpropanoid isolated from Lilium longiflorum, exhibits anti-inflammatory activity by inhibiting the expression of iNOS (inducible nitric oxide synthase) and COX-2 (cyclooxygenase-2). | |||
T2980 | Chondroitin sulfate | Chonsurid,Chondroitin polysulfate | MMP , Others , Endogenous Metabolite , NO Synthase |
Chondroitin sulfate (Chonsurid) is extracted from shark bone;Store the product in sealed, cool and dry condition | |||
T2S2335 | Dehydroevodiamine | DHED | Others , NF-κB , COX , PGE Synthase , NO Synthase |
Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant, inhibition of nitric oxide production and cerebral blood fl... | |||
T1310 | 2-Thiouracil | Thiouracil,Deracil | Thyroid hormone receptor(THR) , NO Synthase |
2-Thiouracil (Deracil) is a thiolated uracil derivative that is a known anti-hyperthyroid agent. | |||
T3S0364 | L-Arginine | L-Arg,(S)-(+)-Arginine | IL Receptor , Endogenous Metabolite , NO Synthase |
1. L-Arginine (L-Arg) exhibits anti-atherosclerotic effect. 2. L-Arginine and soy enriched diet are effective in prevention of osteoporosis associated with diabetes mellitus. 3. Exogenous L-Arginine could enhance neonate... | |||
T3918 | Ginsenoside Rb3 | Gypenoside IV | NF-κB , COX , NO Synthase |
Ginsenoside Rb3 (Gypenoside IV) is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB transcriptional activity. It also inhibits the induction of COX-2 and iNOS mRNA. | |||
T7030 | Anemarsaponin B | p38 MAPK , NF-κB , MEK , COX , NO Synthase | |
Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activity, possibly via the p38 MAP kinase pathway. Anemarsaponin B c... | |||
TN1373 | α-Humulene | Alpha-caryophyllene | TNF , NOS , COX |
α-Humulene (Alpha-caryophyllene) is extracted from S.officinalis essential oil.α-Humulene can inhibit tumor cell growth.α-Humulene also shows anti-inflammatory effects, probably by interfering with TNFalpha production an... | |||
T7786 | Tryptanthrin | DNA gyrase | |
Tryptanthrin is a natural DNA gyrase inhibitor. | |||
T5681 | ETHYL CAFFEATE | ETHYL 3,4-DIHYDROXYCINNAMATE | NF-κB , COX , PGE Synthase , NO Synthase |
Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro. Furthermore, Ethyl Caffeate intensely blocked the transcriptional expression in interferon-γ-related s... | |||
T3811 | Ginsenoside C-K | Ginsenoside compound K,Ginsenoside K | P450 , cell cycle arrest , COX , NO Synthase |
Ginsenoside C-K (Ginsenoside K) is a bacterial metabolite of G-Rb1 exhibiting anti-inflammatory effects by reducing iNOS and COX-2. | |||
T5684 | Ethyl 3,4-dihydroxybenzoate | Apoptosis , Others , Reactive Oxygen Species , HIF/HIF Prolyl-Hydroxylase , NO Synthase , Autophagy | |
Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain. | |||
T3805 | Prim-O-glucosylcimifugin | Cimifugin beta-D-glucopyranoside,Cimifugin 7-glucoside | TNF , COX , JAK , NO Synthase |
Prim-O-glucosylcimifugin (Cimifugin 7-glucoside) can inhibit the proliferation of SMC(smooth muscle cell) stimulated by TNF-alpha, increase the proportion of G0/G1 phase. | |||
T3779 | Crocin II | Crocin 2,Crocetin gentiobiosylglucosyl ester,Tricrocin,Crocin B | Caspase , COX , NO Synthase |
Crocin II (Crocetin gentiobiosylglucosyl ester) has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect of crocin is mainly mediated by reducing the protein expres... | |||
T5S0754 | Isoquercetin | 3-Glucosylquercetin,Hirsutrin,Isoquercitrin,Quercetin 3-o-glucopyranoside | NF-κB , Wnt/beta-catenin , NO Synthase |
1. Isoquercetin (3-Glucosylquercetin) is a potential stimulator of bone mineralization used for prophylaxis of osteoporotic disorders. 2. Isoquercetin may be as a potential therapeutic agent against neurodegeneration in ... | |||
T3S0401 | Piceatannol 3'-O-glucoside | Piceatannol 3-glycoside,Quzhaqigan | Arginase , NO Synthase |
Piceatannol 3'-O-glucoside (Piceatannol 3-glycoside) increases pulmonary blood oxygen tension and decreases pulmonary interstitial edema, so it can protect lung injury. | |||
T2758 | Madecassic acid | 6-Deoxy-L-Galactose,L-Fucose,Brahmic acid,L-fucopyranose | Others , TNF , COX , NO Synthase , Interleukin |
Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica. | |||
T0670 | L-Arginine hydrochloride | (S)-(+)-Arginine hydrochloride,L-Arginine HCl (L-Arg),L-arginine monohydrochloride | Amino Acids and Derivatives , Endogenous Metabolite , NO Synthase |
L-Arginine hydrochloride is a nitrogen donor for synthesis of nitric oxide. | |||
TN1102 | Physalin L | Others , NO Synthase | |
Physalin L is a natural product,it shows a distinct fluorescence spot under UV 365 nm with good separation. | |||
TN1109 | 3-O-Acetyl-16α-hydroxydehydrotrametenolic acid | 3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid | NOS , NO Synthase , Prostaglandin Receptor |
3-O-Acetyl-16α-hydroxydehydrotrametenolic acid (3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid) shows anti-inflammatory activity, it can inhibit NO production and iNOS expression in LPS-stimulated Raw264.7 cells. | |||
T5915 | D-chiro-Inositol | D-(+)-CHIRO-INOSITOL | Endogenous Metabolite |
D-chiro-Inositol (D-(+)-CHIRO-INOSITOL) is an epimer of myo-inositol that is found in certain mammalian glycosylphosphatidylinositol protein anchors and inositol phosphoglycans possessing insulin-like bioactivity. | |||
T3671 | Vitexin-2"-O-rhamnoside | 2''-O-Rhamnosylvitexin,Vitexin-2-O-rhaMnoside,Vitexin-2''-O-rhamnoside,Apigenin-8-C-glucoside | Others |
Vitexin-2"-O-rhamnoside (Apigenin-8-C-glucoside) is a compound contributes to the protection against H O -mediated oxidative stress damage. | |||
T5073 | Inosine 5'-monophosphate disodium salt hydrate | Inosine 5'-monophosphate disodium salt,5'-IMP-Na2,Disodium 5'-inosinate monohydrate | Others , Endogenous Metabolite |
Inosine 5'-monophosphate disodium salt hydrate (Inosine 5'-monophosphate disodium salt), or inosinic acid, is the ribonucleotide of hypoxanthine and the first nucleotide formed during purine synthesis. | |||
T4971 | 5'-DEOXYADENOSINE | 5′-dAdo | Endogenous Metabolite |
5'-Deoxyadenosine (5′-dAdo) is an oxidized nucleoside found in the urine of normal subjects. Oxidized nucleosides represent excellent biomarkers for determining the extent of damage in genetic material, which has long be... | |||
T4715 | 2'-Deoxyguanosine monohydrate | Guanine-2'-deoxyriboside | Others , Endogenous Metabolite |
2'-Deoxyguanosine monohydrate (Guanine-2'-deoxyriboside) is a nucleoside consisting of the base guanine and the sugar deoxyribose. It is like guanosine, but with one oxygen atom removed. It is a nucleoside component of D... | |||
T3849 | Kinsenoside | (+)-Kinsenoside | Apoptosis , Nrf2 |
Kinsenoside ((+)-Kinsenoside) shows significant antihepatotoxic, and anti-inflammatory activities. Kinsenoside could be useful for repairing beta cells in pancreatic islet injury as well as improving its function, it cou... | |||
T4875 | Palatinose hydrate | 6-O-α-D-Glucopyranosyl-D-fructose, Isoma | Others , Endogenous Metabolite |
Palatinose hydrate (6-O-α-D-Glucopyranosyl-D-fructose, Isoma) is a disaccharide having an α(1→6) linkage between D-glucose and D-fructose and is similar to sucrose in its physicochemical properties. It is produced from s... | |||
T3843 | Pinosylvin | 3,5-stilbenediol,5-Styrylresorcinol | Apoptosis , Others , Antibacterial , Autophagy |
Pinosylvin (5-Styrylresorcinol) induces autophagy via AMPK activation. Pinosylvin is likely to act as a pro-angiogenic factor. | |||
TN6745 | PALATINOSE | TNP-470,Isomaltulose | Others |
PALATINOSE (TNP-470) is a natural occurring disaccharide composed of alpha-1,6-linked glucose and fructose。 PALATINOSE has a beneficial effect on liver metabolic functions and might therefore be a good substitute for suc... | |||
T3910 | Pulchinenoside C | Anemoside B4,Chinensioside A,Pulchinenoside B4,Pulsatilla saponin B4 | IL Receptor |
Pulchinenoside C (Anemoside B4) is an abundant triterpenoid saponin isolated from P. chinensis and exerts anti-inflammatory and antioxidant effects. | |||
T11398 | Ginsenoside Ra3 | Others | |
Ginsenoside Ra3 is a natural product isolated from Panax ginseng, has anti-cancer activity. | |||
TN6747 | Phenyl-β-D-glucopyranoside | PHENYL-B-D-GLUCOPYRANOSIDE | Others |
Phenyl-β-D-glucopyranoside (PHENYL-B-D-GLUCOPYRANOSIDE) is a component of Phellodendron amurense with anti-cancer and anti-inflammatory activities. | |||
T5583 | Turanose | D-(+)-Turanose | Endogenous Metabolite |
D(+)-Turanose (D-(+)-Turanose) is a naturally occuring compound. It is a reducing disaccharide. | |||
T5065 | GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD | Monosodium-GMP,cGMP sodium salt,Cyclic GMP | PKA |
GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD (cGMP sodium salt) , also known as cGMP, is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, inc... | |||
T7090 | Jionoside A1 | Others | |
Jionoside A1 is isolated and purified from the roots of Rehmannia glutinosa. It displays dose-dependent immune-enhancement activity and possesses moderate neuroprotective activities on H2O2-treated SH-SY5Y cells. | |||
T5761 | Notoginsenoside Ft1 | Others , HIF/HIF Prolyl-Hydroxylase | |
Notoginsenoside Ft1 is a saponin originally isolated from P. notoginseng with diverse biological activities | |||
TN2260 | Taxifolin 7-O-rhamnoside | Taxifolin 7-O-α-L-rhamnoside | Others |
Taxifolin 7-O-rhamnoside (Taxifolin 7-O-α-L-rhamnoside) is a natural product from Hypericum japonicum. | |||
T14128 | Adenosylcobalamin | Cobamamide,Coenzyme B12,AdoCbl | Endogenous Metabolite |
Adenosylcobalamin (AdoCbl) is a biologically active form of vitamin B12 .It is a cofactor for methylmalonyl CoA mutase. It belongs to the corrinoid group of compounds, which contain a corrin macrocycle, and is produced o... | |||
TN6594 | Bidenoside C | Others | |
Bidenoside C is a flavonoid found in brazilian propolis, the first of its kind to be isolated from a herb of the genus Leech, and has anti-proliferative activity against cancer cells. | |||
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Cat No. | Product Name | Species | Expression System |
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TMPY-03172 | Argininosuccinate lyase Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
The recycling of citrulline by argininosuccinate synthase 1 (ASS1) and argininosuccinate lyase (ASL) is crucial to maintain arginine availability and nitric oxide (NO) production. Nitric oxide (NO) plays an established r... | |||
TMPH-01603 | Lanosterol synthase/LSS Protein, Human, Recombinant (His) | Human | E. coli |
Key enzyme in the cholesterol biosynthesis pathway. Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Through the production of lanosterol may regulate lens prote... | |||
TMPH-03178 | TusA Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) | Pseudomonas aeruginosa | E. coli |
Sulfur carrier protein which probably makes part of a sulfur-relay system. | |||
TMPH-03164 | Beta-lactamase OXA-10 Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) | Pseudomonas aeruginosa | E. coli |
Hydrolyzes both carbenicillin and oxacillin. | |||
TMPH-03167 | ToxR Protein, Pseudomonas aeruginosa, Recombinant (His) | Pseudomonas aeruginosa | E. coli |
Positive regulation of toxA gene transcription. | |||
TMPH-03171 | Lysyl endopeptidase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) | Pseudomonas aeruginosa | E. coli |
Lysine-specific endoprotease. Involved in corneal virulence. | |||
TMPH-03176 | LasA Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) | Pseudomonas aeruginosa | E. coli |
Involved in proteolysis and elastolysis (degradation of the host protein elastin). Has staphylolytic activity (degrades pentaglycine cross-links in cell wall peptidogylcan), preferring Gly-Gly-|-X substrates where X is A... | |||
TMPH-03179 | LpxC Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO) | Pseudomonas aeruginosa | E. coli |
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. | |||
TMPH-03066 | PatA Protein, Nostoc sp., Recombinant (His & Myc) | Nostoc sp. | E. coli |
Controls heterocyst pattern formation. Required for the differentiation of intercalary heterocysts but not for terminal heterocysts. | |||
TMPH-03172 | OprI Protein, Pseudomonas aeruginosa, Recombinant (His) | Pseudomonas aeruginosa | E. coli |
TMPH-03174 | LecA Protein, Pseudomonas aeruginosa, Recombinant (His) | Pseudomonas aeruginosa | E. coli |
D-galactose specific lectin. Binds in decreasing order of affinity: melibiose, methyl-alpha-D-galactoside, D-galactose, methyl-beta-D-galactoside, N-acetyl-D-galactosamine. Similar to plant lectins in its selective (carb... | |||
TMPH-03065 | Alr2278 Protein, Nostoc sp., Recombinant (His & MBP) | Nostoc sp. | Baculovirus |
Alr2278 Protein, Nostoc sp., Recombinant (His & MBP) is expressed in Baculovirus. | |||
TMPH-03175 | Porin P Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) | Pseudomonas aeruginosa | E. coli |
Anion specific, the binding site has higher affinity for phosphate than chloride ions. Porin O has a higher affinity for polyphosphates (tripolyphosphate and pyrophosphate) while porin P has a higher affinity for orthoph... | |||
TMPH-03170 | PvdA Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) | Pseudomonas aeruginosa | E. coli |
Catalyzes the conversion of L-ornithine to N(5)-hydroxyornithine, the first step in the biosynthesis of all hydroxamate-containing siderophores, such as pyoverdin. Pyoverdin is a hydroxamate siderophore composed of a 6,7... | |||
TMPH-00346 | Limulus clotting factor C Protein, Carcinoscorpius rotundicauda, Recombinant (His) | Carcinoscorpius rotundicauda | E. coli |
This enzyme is closely associated with an endotoxin-sensitive hemolymph coagulation system which may play important roles in both hemostasis and host defense mechanisms. Its active form catalyzes the activation of factor... | |||
TMPH-03166 | Elastase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) | Pseudomonas aeruginosa | E. coli |
Cleaves host elastin, collagen, IgG, and several complement components as well as endogenous pro-aminopeptidase. Autocatalyses processing of its pro-peptide. Processes the pro-peptide of pro-chitin-binding protein (cbpD)... | |||
TMPH-03180 | LpxC Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) | Pseudomonas aeruginosa | E. coli |
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. | |||
TMPH-03168 | Exotoxin A Protein, Pseudomonas aeruginosa, Recombinant (His & KSI) | Pseudomonas aeruginosa | E. coli |
An NAD-dependent ADP-ribosyltransferase (ADPRT). Catalyzes the transfer of the ADP ribosyl moiety of oxidized NAD (NAD(+)) onto eukaryotic elongation factor 2 (eEF-2) thus arresting protein synthesis. Has an LD(50) of 65... | |||
TMPH-03165 | Beta-lactamase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) | Pseudomonas aeruginosa | E. coli |
TMPH-00046 | Aln g I Protein, Alnus glutinosa, Recombinant (Yeast, His) | European alder | Yeast |
TMPY-03985 | Adenosine Deaminase Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Adenosine Desaminase (ADA) deficiency, is a purine metabolic disorder that cause severe combined immunodeficiency (SCID) due to the accumulation of toxic metabolites that primarily affects development, differentiation a... | |||
TMPH-03173 | OprF Protein, Pseudomonas aeruginosa, Recombinant (His) | Pseudomonas aeruginosa | E. coli |
Has porin activity, forming small water-filled channels. Also has a structural role in determining cell shape and ability to grow in low-osmolarity medium. | |||
TMPH-00130 | Mannosyl-oligosaccharide alpha-1,2-mannosidase 1B Protein, Aspergillus phoenicis, Recombinant (His & Myc) | Aspergillus phoenicis | E. coli |
Mannosyl-oligosaccharide alpha-1,2-mannosidase 1B Protein, Aspergillus phoenicis, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-02034 | Retinoschisin Protein, Human, Recombinant (His) | Human | E. coli |
Retinoschisin Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPH-03407 | NIFH Protein, Rhizobium leguminosarum, Recombinant (GST & His & Myc) | Rhizobium leguminosarum | E. coli |
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein. | |||
TMPH-03649 | HSP100 Protein, Trypanosoma cruzi, Recombinant (His & Myc) | Trypanosoma cruzi | E. coli |
HSP100 Protein, Trypanosoma cruzi, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-03064 | All1616 Protein, Nostoc sp., Recombinant (His) | Nostoc sp. | E. coli |
All1616 Protein, Nostoc sp., Recombinant (His) is expressed in E. coli. | |||
TMPH-02461 | PylS Protein, Methanosarcina barkeri, Recombinant (His) | Methanosarcina barkeri | E. coli |
Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG. | |||
TMPH-03169 | PLC-H Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO) | Pseudomonas aeruginosa | E. coli |
Hydrolyzes sphingomyelin in addition to phosphatidylcholine. | |||
TMPH-03177 | RhlR Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO) | Pseudomonas aeruginosa | E. coli |
Necessary for transcriptional activation of the rhlAB genes encoding the rhamnosyltransferase. It also functions as a transcriptional activator of elastase structural gene (lasB). Binds to autoinducer molecules BHL (N-bu... | |||
TMPH-03648 | Cruzipain Protein, Trypanosoma cruzi, Recombinant (His & Myc) | Trypanosoma cruzi | E. coli |
Cruzipain Protein, Trypanosoma cruzi, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-00045 | Aln g I Protein, Alnus glutinosa, Recombinant (E. coli, His) | Alnus glutinosa | E. coli |
TMPH-03063 | Cyanovirin-N Protein, Nostoc ellipsosporum, Recombinant (His) | Nostoc ellipsosporum | E. coli |
Mannose-binding lectin. | |||
TMPH-00167 | L-arabinose isomerase Protein, Bacillus subtilis, Recombinant (His & Myc) | Bacillus subtilis | E. coli |
L-arabinose isomerase Protein, Bacillus subtilis, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-01733 | DDAH2 Protein, Human, Recombinant (GST & His) | Human | E. coli |
Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. | |||
TMPH-01732 | DDAH1 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. | |||
TMPH-02526 | Arginase-2/ARG2 Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synth... | |||
TMPH-02524 | Arginase-1/ARG1 Protein, Mouse, Recombinant (His) | Mouse | Yeast |
Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell ... | |||
TMPH-02525 | Arginase-1/ARG1 Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell ... |
Cat No. | Product Name | ||
---|---|---|---|
L8400 | Hematonosis Compound Library | 524 compounds | |
A unique collection of 524 compounds related to hematologic diseases for high throughput screening (HTS) and high content screening (HCS); |