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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T24141 | HIV-1 Inhibitor 18A | HIV-1 Inhibitor-18A | HIV Protease |
HIV-1 Inhibitor 18A (HIV-1 Inhibitor-18A) specifically inhibits the entry of multiple HIV-1 isolates. | |||
TP1149 | HIV-1 Rev (34-50) | HIV-1 Rev 34-50,HIV-1 rev Protein (34-50) | HIV Protease |
HIV-1 Rev (34-50) (HIV-1 rev Protein (34-50)) is a 17 amino acid peptide with anti-HIV-1 activity. HIV-1 Rev (34-50) is derived from the Rev-responsive element-binding domains of Rev in HIV-1. | |||
T67833 | HIV-1 inhibitor-54 | HIV Protease | |
HIV-1 inhibitor-54 is a potent HIV-1 inhibitor showing anti-HIV activity (EC50 : 32 nM) against WT HIV-1 (strain IIIB) x in MT-4 cells.HIV-1 inhibitor-54 can be used to study viral infections. | |||
T9039 | HIV-1 Nef-IN-1 | HIV Protease | |
HIV-1 Nef-IN-1 is an inhibitor of HIV-1 Nef protein. It efficiently competes for Nef-SH3Hck interactions(Kd : 6.7 μM). | |||
T9854 | HIV-1 inhibitor-6 | 3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo- | HIV Protease |
HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicing inhibitor that blocks HIV replication. | |||
T61793 | HIV-IN-6 | HIV Protease | |
HIV-IN-6 is an HIV viral inhibitor that inhibits the replication of the HIV virus.HIV-IN-6 has anti-HIV viral activity and works by targeting Src family kinases (SFK) (e.g., Hck) that interact with the viral Nef protein. | |||
T60742 | HIV-1 integrase inhibitor 8 | HIV Protease | |
HIV-1 integrase inhibitor 8 is an inhibitor of HIV-1 integrase. Integration is a required step in HIV replication [1]. | |||
TP1637 | HIV gag peptide (197-205) | HIV gag peptide 197-205 | |
HIV gag peptide (197-205) is a H-2Kd-restricted epitope derived from the p24 portion of the HIV-1 gag protein and composed of the amino acid 197-205 (AMQMLKETI). | |||
TP1674 | HIV p17 Gag (77-85) | HIV p17 Gag 77-85 | |
HIV p17 Gag (77-85) is an attractive target for molecular intervention, because it is involved in the viral replication cycle at both the pre- and postintegration levels. In the present experiments, we targeted p17 by in... | |||
T40719 | (Cys47)-HIV-1 tat Protein (47-57) | (Cys47)-HIV-1 tat Protein (47-57) | |
(Cys47)-HIV-1 tat Protein (47-57) possesses membrane translocation functionality and can serve as a surface derivatization agent for magnetic pharmaceuticals, thereby enhancing their uptake into specific target cells. | |||
T39729 | HIV Protease Substrate 1 | ||
HIV Protease Substrate 1 is a fluorogenic compound that offers insights into the enzymatic activity of HIV protease, making it a valuable tool for studying this aspect. | |||
TP1743 | MPG, HIV related | ||
MPG, a 27-amino acid peptide compound, is derived from the fusion peptide domain of HIV-1 gp41 and the nuclear localisation sequence of SV40 large T antigen. As a potent delivery agent, MPG enables efficient and widespre... | |||
T11564 | HIV-1 inhibitor-3 | Others | |
HIV-1 inhibitor-3 is an HIV infection inhibitor. | |||
T11566 | HIV-1 integrase inhibitor | Others | |
Hiv-1 integrase inhibitor is an effective anti-HIV drug. | |||
TP1776 | HIV-1 TAT 48-60 | ||
HIV-1 TAT (48-60) is a cell-penetrating peptide derived from the human immunodeficient virus (HIV)-1 Tat protein residue 48-60. This is one of the cell-penetrating peptides generated from the human immunodeficient virus ... | |||
T11565 | HIV-1 integrase inhibitor 7 | Others | |
HIV-1 integrase inhibitor 7 is a potent HIV-1 integrase inhibitor (IC50: 33.3 nM). | |||
T11568 | HIV-1 integrase inhibitor 4 | Others | |
HIV-1 integrase inhibitor 4 is an HIV-1 integrase strand transfer (INST) inhibitor (IC50: 3.7 nM). | |||
T11567 | HIV-1 integrase inhibitor 3 | Others | |
HIV-1 integrase inhibitor 3 is an HIV-1 integrase strand transfer (INST) inhibitor (IC50: 2.7 nM). | |||
T76502 | HIV-1, HIV-2 Protease Substrate | ||
HIV-1, HIV-2 Protease Substrate is a compound serving as the substrate for the proteases of both HIV-1 and HIV-2, featuring four residues that allow for conservative substitutions at the substrate binding sites of these ... | |||
T74282 | HIV-IN-2 | ||
HIV-IN-2 (Compound 100) is a potent inhibitor of HIV, showing potential for research into HIV infection [1]. | |||
T76490 | Fluorescent HIV Substrate | ||
Fluorescent HIV Substrate is a HIV substrate. | |||
T64048 | HIV-IN-5 | ||
HIV-IN-5 (compound 5r) is a potent inhibitor of HIV-1 (IC50: 0.16 μM). HIV-IN-5 binds to NNIBP (NNRTIs (non-nucleoside reverse transcriptase inhibitors) binding sites). ). | |||
T27030 | CK176 | HIV-1 inhibitor-34,HIV-1 inhibitor 34,CK 176,CK-176,HIV-1 inhibitor34 | |
CK176 is a capsid targeted inhibitor of HIV-1 replication. CK176 shows an 11-fold improvement over I-XW-053 in blocking HIV-1 replication in primary human peripheral blood mononuclear cells (PBMCs). | |||
T62978 | HIV-IN-3 | ||
HIV-IN-3 (Compound 22a) is a potent inhibitor of HIV (IC50: 1.5 μM). HIV-IN-3 has potential for the study of HIV-related diseases. | |||
T60426 | HIV-IN-4 | ||
HIV-IN-4 (Compound 12) is a potent HIV inhibitor that exhibits promising anti-HIV activities [1]. | |||
T79974 | HIV-IN-8 | ||
HIV-IN-8 (Compound 9) acts as an HIV inhibitor, suppressing HIV replication with an effective concentration (EC50) of 13 μg/mL [1]. | |||
T76603 | HIV-IN petide | ||
HIV-IN petide is a competitive inhibitor of HIV-1 protease (K i =50 nM) [1] . | |||
T82194 | HIV-IN-9 | ||
HIV-IN-9 (Compound 2b) is an HIV inhibitor with an IC50 value of 6.65 μg/mL, demonstrating high binding affinity for HIV-RT. Additionally, it inhibits the cytochrome P450 isoenzymes CYP3A4, CYP1A2, CYP2C1, and CYP2D6 [1]... | |||
T77792 | HIV Peptide T | ||
HIV Peptide T (Peptide T), this synthetic octapeptide is an antiviral drug in the treatment of HIV infection. It mainly competitively inhibits the interaction between gp120 (HIV surface protein) and the CD4 receptor, whi... | |||
T78834 | HIV-IN-7 | HIF/HIF Prolyl-Hydroxylase | |
Axl-IN-16 (Compound 4), an Axl inhibitor, not only suppresses Axl expression and HIF activity but also triggers fruiting body formation in Flammulina velutipes. This compound can be extracted from the "fruiting liquid (F... | |||
T63813 | HIV-1 inhibitor-39 | ||
HIV-1 inhibitor-39 is a potent inhibitor of HIV-1 (EC50>112.88 μM). HIV-1 inhibitor-39 has anti-RT (HIV-1 reverse transcriptase) effect (IC50: 15.75 μM). HIV-1 inhibitor-39 exhibits cytotoxicity against MT-4 cells (CC50:... | |||
T62010 | HIV-1 inhibitor-20 | ||
HIV-1 inhibitor-20 is a potent HIV-1 inhibitor. | |||
T63963 | HIV-1 inhibitor-14 | ||
HIV-1 inhibitor-14 is a potent, broad-spectrum inhibitor of HIV-1 non-nucleoside reverse transcriptase (RT) (IC50=0.14 μM for HIV-1 RT). HIV-1 inhibitor-14 inhibits both wild-type and drug-resistant HIV-1 strains (EC50: ... | |||
T63018 | HIV-1 inhibitor-43 | ||
HIV-1 inhibitor-43 is a potent inhibitor of HIV-1, acting on HIV-1 Y188L (EC50: 21.3 nM), K103N-Y181C (EC50: 6.2 nM), K103N (EC50< 0.7 nM) and Y181C (EC50< 0.7 nM). HIV-1 inhibitor-43 reduces the expression of HIV-1 RNA ... | |||
T76485 | HIV Protease Substrate I | ||
HIV Protease Substrate I, a chromogenic substrate for HIV-1 protease, contains the protease's cleavage site [1]. | |||
T62526 | HIV-1 inhibitor-8 | ||
HIV-1 inhibitor-8 is a potent, orally active, low toxicity HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI). HIV-1 inhibitor-8 is capable of acting on WT HIV-1 reverse transcriptase (IC50: 0.081 μM). HIV-1 in... | |||
T62782 | HIV-1 inhibitor-34 | ||
HIV-1 inhibitor-34 (compound 5q) is a potent, selective HIV-1 inhibitor that acts on HIV-1 (EC50: 6.4 nM), MT-4 cells (CC50: 16 μM). HIV-1 inhibitor-34 can be used in AIDS research. | |||
T62319 | HIV-1 inhibitor-44 | ||
HIV-1 inhibitor-44 (compound 11l) is an HIV-1 reverse transcriptase inhibitor that exhibits activity against wild-type HIV-1 strains (EC50: 0.209 μM). | |||
T62287 | HIV-1 inhibitor-42 | ||
HIV-1 inhibitor-42 (compound 5b) is a potent inhibitor of HIV-1 (IC50: 0.06 μM). HIV-1 inhibitor-42 inhibits HIV-1 RT RNA-dependent DNA polymerase (IC50: 0.518 μM) and DNA-dependent DNA polymerase (IC50. 0.072 μM). | |||
T62690 | HIV-1 inhibitor-46 | ||
HIV-1 inhibitor-46 (compound 13d) is a potent inhibitor of HIV-1 non-nucleoside reverse transcriptase (EC50: 1.425 μM). HIV-1 inhibitor-46 can be used in the study of AIDS. | |||
T61801 | HIV-1 inhibitor-35 | ||
HIV-1 inhibitor-35 (compound 74) is a highly potent inhibitor of the HIV-1 virus, exhibiting EC50 values of 80 nM and 70 nM for LTR and CMV, respectively, in HEK293 cells. Additionally, HIV-1 inhibitor-35 demonstrates in... | |||
T61797 | HIV-1 inhibitor-15 | ||
HIV-1 inhibitor-15 (compound 9d) is a potent and broad-spectrum inhibitor targeting HIV-1. It exhibits inhibitory activity against HIV-1 WT, L100I, K103N, Y181C, and E138K with respective EC50 values of 1.7 nM, 4 nM, 2 n... | |||
T78749 | HIV-1 inhibitor-57 | ||
HIV-1 Inhibitor-57 (Compound 12g) is an antiviral agent that potently inhibits both wild-type and five common NNRTI-resistant strains of HIV-1, exhibiting EC50 values between 0.024 and 0.0010 μM. It achieves this efficac... | |||
T61670 | HIV-1 inhibitor-38 | ||
HIV-1 inhibitor-38 (Compound 91) is a powerful agent that inhibits the activity of HIV-1. It exhibits great potential as a novel latency reversing agent, making it a promising candidate for further development [1]. | |||
T79324 | HIV-1 inhibitor-59 | ||
HIV-1 Inhibitor-59 (Compound I-5b) effectively inhibits both wild-type and mutant strains of HIV-1, with EC50 values ranging from 5.62 to 171 nM. Additionally, it demonstrates moderate inhibitory activity against the rev... | |||
T63363 | HIV-1 inhibitor-19 | ||
HIV-1 inhibitor-19 is a potent inhibitor of HIV-1 non-nucleoside reverse transcriptase (NNRTI) that acts on L100I, K103N and V106A/F227L mutant strains with EC50s of 7.3 nM, 9.2 nM and 21.0 nM, respectively. | |||
T78925 | HIV-1 inhibitor-58 | ||
HIV-1 Inhibitor-58 (Compound 10c) is a non-nucleoside reverse transcriptase inhibitor with broad-spectrum antiviral properties, effective against both wild-type strain IIIB and NNRTI-resistant strains like K103N and E138... | |||
T72565 | HIV-1 inhibitor-52 | ||
HIV-1 inhibitor-52 is a powerful inhibitor of a broad spectrum of HIV-1 activities, demonstrating effectiveness with EC50 values ranging from 1.6 nM to 6.4 nM against various strains, including WT HIV-1, HIV-1 V370A, HIV... | |||
T76537 | GP120, HIV-1 MN | ||
GP120, HIV-1 MN, a peptide, is utilized in researching HIV infection [1] [2]. | |||
T72534 | HIV-1 inhibitor-10 | ||
HIV-1 inhibitor-10 is a nanomolar HIV-1 maturation inhibitor. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN2283 | Tripterifordin | HIV Protease | |
Tripterifordin shows anti-HIV replication activity in H9 lymphocyte cells with an EC50 of 1 microgram/ml. | |||
T5783 | Rosamultin | Antioxidant , HIV Protease | |
Rosamultin has antioxidant, antiinflammatory/antinociceptive properties,and has anti-human immunodeficiency virus (HIV) activity. | |||
TN1059 | Ganoderic acid B | IL Receptor , HIV Protease , JAK , STAT | |
Ganoderic acid B is a chemical marker in quality control of G. lucidum and related products. Ganoderic acid B-containing herbs has potential influence towards therapeutic window of trifluoperazine.Ganoderic acid B has an... | |||
T6377 | Aloperine | Apoptosis , Virus Protease , HIV Protease , Antibiotic , Autophagy | |
Aloperine exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties. | |||
TN1103 | Diphyllin | ATPase , Proton pump , Influenza Virus , HIV Protease | |
Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling. | |||
T12651 | Rabdosiin | (+)-Rabdosiin | Others |
Rabdosiin ((+)-Rabdosiin) is a natural product, and has anti-allergic activity, anti-HIV activity and inhibition on DNA topoisomerase. | |||
T4S1383 | Escin IA | Aescin IA,Escin IA;Aescin IA,Escin IA | HIV Protease |
Escin IA (Escin IA;Aescin IA) is a triterpene saponin isolated from horse chestnut, which inhibits HIV-1 protease with IC50 values of 35 μM. Escin IA has anti-TNBC metastasis activity, and its action mechanisms involved ... | |||
T6S2391 | L-Chicoric Acid | (-)-Chicoric acid,trans-Caffeoyltartaric acid,Chicoric acid,dicaffeoyltartaric acid | Others , HIV Protease |
L-Chicoric Acid (trans-Caffeoyltartaric acid) has been shown to inhibit hyaluronidase and HIV-1 integrase, and to possess phagoeytosis stimulatory activity in vitro and in vivo and antiviral acitivy. L-Chicoric acid may ... | |||
TQ0217 | Gomisin G | P450 , HIV Protease | |
Gomisin G is a natural compound and exhibits potent anti-HIV activity (EC50: 0.006 μg/mL; therapeutic index: 300). It is a good substrate of CYP2C9. | |||
T4S1387 | Isoescin IA | HIV Protease | |
Isoescin IA is a triterpenoid saponin isolated from the seeds of Aesculus chinensis. It has anti-HIV-1 protease activity. | |||
T0474 | Erythromycin ethylsuccinate | EES | ribosome , HIV Protease , Antibacterial , Antibiotic , Autophagy |
Erythromycin ethylsuccinate (EES) is a macrolide antibiotic, produced by Streptomyces erythreus. | |||
T2942 | Psoralen | Ficusin,Furocoumarin,psoralene | Apoptosis , Influenza Virus , HIV Protease , DNA/RNA Synthesis |
Psoralen (Ficusin) is a furocoumarin that intercalates with DNA, inhibiting DNA synthesis and cell division. | |||
Fr16741 | Oxindole | Indolin-2-one | Others , HIV Protease |
Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.Oxindole structure has been used in receptor tyrosine kinases ... | |||
T3822 | Bellidifolin | Bellidifoline,Bellidifolium | Others , HIV Protease |
Bellidifolin (Bellidifoline) has anti-oxidation, hepatoprotective, anti-inflammatory and antitumor actions, it may contribute to the protective effects associated with nerve injury initiated by hypoxia by mechanisms rela... | |||
T2865 | Oleanolic Acid | Oleanic acid,Caryophyllin | HIV Protease , Endogenous Metabolite , Antibiotic , Autophagy |
Oleanolic Acid (Caryophyllin) is a natural compound with anti-tumor activities, which are widely distributed in plants. | |||
T0966 | Sennoside A | NSC 112929 | MAO , HIV Protease |
Sennoside A (NSC-112929), a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine. | |||
T6841 | Fumagillin | NSC9168,Amebacilin | Others , HIV Protease , Antibiotic , Parasite |
Fumagillin (Amebacilin) is a selective and potent irreversible inhibitor of Methionine aminopeptidase 2 (MetAP2), used as an antibiotic to treat microsporidiosis. | |||
T8689 | Chloroquine | SARS-CoV , TLR , HIV Protease , Antibiotic , Parasite , Autophagy | |
Chloroquine is a Toll-like receptor inhibitor that inhibits autophagy. Chloroquine has anti-malarial and anti-inflammatory activity and is widely used in the treatment of malaria and rheumatoid arthritis. Chloroquine als... | |||
T8116 | Azulene | Bicyclo[5.3.0]Decapentaene | Others , HIV Protease |
Azulene (Bicyclo[5.3.0]Decapentaene) is a natural product. | |||
T2177 | Kaempferol | Kempferol,Robigenin | Apoptosis , Estrogen Receptor/ERR , Mitophagy , Estrogen/progestogen Receptor , HIV Protease , Endogenous Metabolite , Parasite , Autophagy |
Kaempferol (Robigenin) is a natural flavonoid and an inverse agonist of ERRα and ERRγ. Kaempferol has a wide range of antitumor, anti-inflammatory, antioxidant, antibacterial and antiviral activities. | |||
T2S0731 | Trilobatin | P-Phlorizin | Amylase |
Trilobatin (P-Phlorizin) has anti-oxidant effect, can increase superoxide dismutase (SOD) activity.Trilobatin has anti-inflammatory effect, it potentially inhibits the lipopolysaccharide (LPS)-induced inflammatory respon... | |||
T0492 | Dimethyl fumarate | DMF | Reactive Oxygen Species , HIV Protease , Nrf2 , Endogenous Metabolite , Autophagy |
Dimethyl fumarate (DMF), a fumarate derivative, is used as antiinflammatory and immunomodulatory agent. | |||
TN2158 | Robinetin | 3,3',4',5',7-Pentahydroxyflavone | Anti-infection , HIV Protease , Antibacterial |
Robinetin (3,3',4',5',7-Pentahydroxyflavone) has antioxidant and antiradical activities, inhibits EYPC membrane lipid peroxidation and HbA glycosylation with high efficiency. | |||
T4962 | Zingibroside R1 | Ginsenoside Z-R1 | HIV Protease |
Zingibroside R1 (Ginsenoside Z-R1) has anti-HIV-1 activity. | |||
T1131 | Ivermectin | MK-933 | Mitophagy , GluCls , P2X Receptor , SARS-CoV , HIV Protease , Antibiotic , Parasite , Autophagy , HSV |
Ivermectin (MK-933) is a glutamate-gated chloride channel (GluCls) activator, with antiparasitic activity. | |||
T0200 | α-Lipoic Acid | Thioctic acid,DL-α-Lipoic acid,(±)-α-Lipoic acid | Apoptosis , NF-κB , HIV Protease , Mitochondrial Metabolism , Endogenous Metabolite |
α-Lipoic Acid (DL-α-Lipoic acid) an octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme ... | |||
T2789 | Scutellarin | Breviscapin,Breviscapinun,Breviscapine,Scutellarein-7-glucuronide | Akt , HIV Protease , STAT |
Scutellarin (Scutellarein-7-glucuronide), an active flavone isolated from Scutellaria baicalensis, can inhibit RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts, and down-regulate the STAT3/Girdin/Akt signal... | |||
T2728 | Limonin | Dictamnolactone,Limonoic acid 3,19:16,17 dilactone,Obaculactone,Citrolimonin | Apoptosis , HIV Protease , Endogenous Metabolite |
Limonin (Citrolimonin) is a triterpenoid enriched in citrus fruits, which has antivirus and antitumor ability. | |||
T7991 | 2-Hydroxycinnamic acid | Others , SARS-CoV , HIV Protease | |
2-Hydroxycinnamic acid is a natural product isolated from Angraecum fragrans, has photooxidant activity. | |||
T1284 | Megestrol acetate | SC10363,BDH1298 | Glucocorticoid Receptor , Estrogen/progestogen Receptor , Progesterone Receptor , HIV Protease , Autophagy |
Megestrol acetate (BDH1298) is a progestogen with actions and uses similar to those of the progestogens in general. Megestrol acetate also has anti-androgenic properties. It is given by mouth in the palliative treatment ... | |||
T3122 | Fangchinoline | Tetrandrine B,(+)-Limacine,Hanfangichin B,(+)-Fangchinoline | Apoptosis , FAK , HIV Protease , Autophagy |
Fangchinoline (Tetrandrine B) is extracted from Stephania tetrandra S. Moore. | |||
T16791 | Rottlerin | Mallotoxin,NSC 56346,NSC 94525 | CaMK , Apoptosis , Others , HIV Protease , PKA , PKC , Autophagy |
Rottlerin (NSC-56346) is a natural product purified from Mallotus Philippinensis and is a specific PKC inhibitor (IC50: PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKCε,η,ζ of 80-100 μM). Rottlerin causes apoptosis via caspase... | |||
T22468 | 1-Deoxymannojirimycin hydrochloride | Others , Influenza Virus , HIV Protease | |
α-mannosidase I inhibitor | |||
T3730 | Methyl gallate | NSC 363001,Gallicin,Gallic acid methyl ester,Gallincin | Reactive Oxygen Species , HIV Protease , Reverse Transcriptase , Antibacterial |
Methyl gallate (Gallincin) is a reverse transcriptase inhibitor with antioxidant, anti-HIV-1 and HIV-1 enzyme inhibition activities. | |||
T2775 | Baicalin | Baicalein 7-O-β-D-glucuronide | NF-κB , HIV Protease , GABA Receptor , Autophagy |
Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIV properties. | |||
T5782 | Bevirimat | YK FH312,MPC-4326,PA-457 | HIV Protease |
Bevirimat (PA-457) is a first-in-class inhibitor of HIV-1 maturation, blocking the cleavage of the Gag capsid (CA) precursor, CA-SPI, to mature CA protein during virion maturation. | |||
T2830 | Betulinic acid | ALS-357,Lupatic acid,Betulic acid | Apoptosis , Mitophagy , NF-κB , HIV Protease , Topoisomerase , Endogenous Metabolite , Aminopeptidase , Autophagy |
Betulinic acid (ALS-357) is a pentacyclic lupane-type triterpene derivative of betulin (isolated from the bark of Betula alba, the common white birch) which has antiretroviral, antimalarial, and anti-inflammatory propert... | |||
T0194 | Chloroquine phosphate | Chloroquine diphosphate,Aralen phosphate,Chingamin phosphate | SARS-CoV , TLR , HIV Protease , Antibiotic , Parasite , Autophagy |
Chloroquine phosphate (Aralen phosphate) is an aminoquinoline antimalarial and also is widely used as an autophagy inhibitor. Chloroquine also is an inhibitor of toll-like receptors (TLRs). | |||
T0070 | Pentoxifylline | Oxpentifylline,PTX,BL-191 | HIV Protease , PDE , Adenosine Receptor , Autophagy |
Pentoxifylline (PTX) modulates immunologic activity by stimulating cytokine production. Pentoxifylline is a methylxanthine derivative that inhibits phosphodiesterase and affects blood rheology. It also inhibits platelet ... | |||
T0710 | L-Cycloserine | Levcycloserine,Levcicloserina,(-)-Cycloserine,(S)-Cycloserine,Levcycloserinum,(S)-4-Amino-3-isoxazolidone | HIV Protease , GABA Receptor |
L-Cycloserine ((-)-Cycloserine) irreversibly inhibits GABA pyridoxal 5′-phosphate-dependent aminotransferase in E. coli, as well in the brains of various animals, results in increased levels of gamma-aminobutyric acid (G... | |||
T3772 | Maslinic acid | 2α-Hydroxyoleanoic Acid,2α-Hydroxyoleanolic acid,Crategolic acid | NF-κB , HIV Protease , DNA/RNA Synthesis , Antibacterial |
Maslinic acid (Crategolic acid) is a DNA polymerase B inhibitor. | |||
T3321 | Oleanonic acid | 3-Oxooleanolic acid,3-Oxoolean-12-en-28-oic Acid,Oleanonic Acid,3-Ketooleanolic Acid | HIV Protease |
Oleanonic acid (3-Ketooleanolic Acid) is relatively non-toxic, hepatoprotective, and exhibits antitumor and andantiviral properties. | |||
T5429 | Theaflavin 3,3'-digallate | 8-Gingerol,TFDG | Virus Protease , Antioxidant , HIV Protease , HSV |
Theaflavin 3,3'-digallate (8-Gingerol) , a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancer chemopreventive actions, it reduces tumor angiogenesis by downregul... | |||
T1020 | Doxorubicin hydrochloride | Adriamycin,Doxorubicin (Adriamycin) HCl,Hydroxydaunorubicin hydrochloride,NSC 123127 | Apoptosis , Mitophagy , HBV , HIV Protease , Topoisomerase , Antibacterial , Antibiotic , AMPK , Autophagy |
Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM). Doxorubicin hydrochloride exhibits cytotoxicity and antitum... | |||
T1125 | Shikonin | NSC 252844,Isoarnebin 4,(+)-Shikonin,Alkanna Red,C.I. 75535,Anchusa acid | TNF , NF-κB , Chloride channel , HIV Protease , PKM |
Shikonin (Anchusa acid) is a natural product, a TMEM16A chloride channel inhibitor (IC50=6.5 μM) and selective PKM2 inhibitor. Shikonin exhibits antitumor, anti-inflammatory and wound healing activities. | |||
T7064 | Valproic Acid | Sodium valproate,2-Propylpentanoic Acid,VPA,Depakine,2-Propylvaleric Acid | Mitophagy , Gamma-secretase , HIV Protease , GABA Receptor , Sodium Channel , HDAC , Autophagy |
Valproic Acid (2-Propylpentanoic Acid) is an HDAC inhibitor that inhibits HDAC1 activity, induces HDAC2 degradation, and is orally active. Valproic Acid can be used in epilepsy and bipolar disorder research. | |||
T1456 | Doxorubicin | Hydroxydaunorubicin,Adriamycin | Topoisomerase , AMPK |
Doxorubicin (Adriamycin) is a Topoisomerase II (Top2) inhibitor with antineoplastic activity. | |||
TN6600 | Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside | HIV Protease | |
Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside is a glucopyranoside that inhibits HIV-2 RNase H with an IC50 of 5.19 μM. | |||
TL0006 | Cichoric Acid | Dicaffeoyltartaric acid,Chicoric Acid | Reactive Oxygen Species , HIV Protease |
Cichoric Acid (Dicaffeoyltartaric acid) is a potent inhibitor of human immunodeficiency virus type-1 (HIV-1) integrase and the replication in tissues. It also a class of cannabinomimetics with CB2 receptor-dependent and ... | |||
T4S1718 | Punicalin | HBV , HIV Protease | |
Punicalin exerts anti-inflammatory, antioxidative, and anti-hepatotoxic activities, it shows inhibitory activity on HIV-1 reverse transcriptase in a dose-dependent manner, with an IC50 of 0.11 microg/ml (0.14 microM). | |||
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Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02882 | HIV-1 (group M, subtype CRF07_BC) gp140 Protein (His) | HIV | HEK293 |
TMPY-01373 | HIV-1 (group M, subtype CRF07_BC) gp120 Protein (His) | HIV | HEK293 |
The HIV-1 gp120 envelope protein, a glycoprotein that is part of the outer layer of the virus, is an essential component in the multi-tiered viral entry process. It presents itself as viral membrane spikes consisting of ... | |||
TMPY-04192 | HIV-1 (group M, subtype B, strain HXB2) p24 Protein (His) | HIV | E. coli |
TMPY-01552 | HIV-1 (group M, subtype B, strain 92418) p24 Protein (His) | HIV | E. coli |
TMPJ-01313 | HIV-1 gp120 Protein (His) | HIV | Human Cells |
Envelope glycoprotein gp160 is single-pass type I membrane protein. The mature envelope protein (Env) consists of a homotrimer of non-covalently associated gp120-gp41 heterodimers. It is cleaved into the following 2 chai... | |||
TMPY-00426 | HIV-1 (group P, strain RBF168) gp140 Protein (hFc) | HIV | HEK293 |
TMPY-01408 | HIV-1 (group M, subtype CRF07_BC) gp140 Protein (hFc) | HIV | HEK293 |
TMPH-01521 | HIV-2 (subtype A, isolate BEN) Protein Vpx (His) | HIV-2 | E. coli |
Plays a role in nuclear translocation of the viral pre-integration complex (PIC), thus is required for the virus to infect non-dividing cells. Targets specific host proteins for degradation by the 26S proteasome. Acts by... | |||
TMPY-00427 | HIV-1 (group P, strain RBF168) gp120 Protein (His) | HIV | HEK293 |
The HIV-1 gp120 envelope protein, a glycoprotein that is part of the outer layer of the virus, is an essential component in the multi-tiered viral entry process. It presents itself as viral membrane spikes consisting of ... | |||
TMPY-04198 | HIV-1 (group O, strain BCF06) p24 Protein (His) | HIV | E. coli |
TMPH-01522 | HIV-2 (subtype A, isolate ROD) Protein Vpx (His) | HIV-2 | Yeast |
Plays a role in nuclear translocation of the viral pre-integration complex (PIC), thus is required for the virus to infect non-dividing cells. Targets specific host proteins for degradation by the 26S proteasome. Acts by... | |||
TMPY-01556 | HIV-1 (group N, strain 06CM-U14296) p24 protein (His) | HIV | E. coli |
TMPY-04061 | HIV-2 (subtype CRF01_AB, strain 07JP_NMC716_clone_01) gp36 Protein (His & MBP) | HIV | E. coli |
TMPY-06486 | HIV-1 (group M, subtype CRF07_BC) gp120 Protein (His), Biotinylated | HIV | HEK293 |
The HIV-1 gp120 envelope protein, a glycoprotein that is part of the outer layer of the virus, is an essential component in the multi-tiered viral entry process. It presents itself as viral membrane spikes consisting of ... | |||
TMPY-04194 | HIV-1 (group M, subtype C, strain 92BR025) p24 Protein (His) | HIV | E. coli |
TMPY-00425 | HIV-1 (group M, subtype A, strain 92UG037.1) gp140 Protein (hFc) | HIV | HEK293 |
TMPY-00316 | HIV-1 (group M, subtype B, isolate BAL) gp120 Protein (His) | HIV | HEK293 |
The HIV-1 gp120 envelope protein, a glycoprotein that is part of the outer layer of the virus, is an essential component in the multi-tiered viral entry process. It presents itself as viral membrane spikes consisting of ... | |||
TMPY-04915 | HIV-1 (group M, subtype B, Isolate MN) gp120 Protein (His) | HIV | HEK293 |
The HIV-1 gp120 envelope protein, a glycoprotein that is part of the outer layer of the virus, is an essential component in the multi-tiered viral entry process. It presents itself as viral membrane spikes consisting of ... | |||
TMPY-04871 | HIV-1 (group M, subtype C, strain 92BR025) gp140 Protein (Fc) | HIV | HEK293 |
TMPY-04196 | HIV-1 (group M, subtype D, strain NDK) p24 Protein (His) | HIV | E. coli |
TMPY-00309 | HIV-1 (group M, subtype B, strain SHIV-89.6P) gp120 Protein (His) | HIV | HEK293 |
The HIV-1 gp120 envelope protein, a glycoprotein that is part of the outer layer of the virus, is an essential component in the multi-tiered viral entry process. It presents itself as viral membrane spikes consisting of ... | |||
TMPY-01558 | HIV-1 (group N, strain 06CM-U14296) gp160 (gp120 subunit) Protein (His) | HIV | HEK293 |
The HIV-1 gp120 envelope protein, a glycoprotein that is part of the outer layer of the virus, is an essential component in the multi-tiered viral entry process. It presents itself as viral membrane spikes consisting of ... | |||
TMPH-01519 | HIV-1 (group M, subtype C, isolate 92BR025) Protein Vpr (His & Myc) | HIV-1 | E. coli |
During virus replication, may deplete host UNG protein, and incude G2-M cell cycle arrest. Acts by targeting specific host proteins for degradation by the 26S proteasome, through association with the cellular CUL4A-DDB1 ... | |||
TMPH-01520 | HIV-1 (group M, subtype K, isolate 96CM-MP535) Protein Vpr (His & Myc) | HIV-1 | E. coli |
During virus replication, may deplete host UNG protein, and incude G2-M cell cycle arrest. Acts by targeting specific host proteins for degradation by the 26S proteasome, through association with the cellular CUL4A-DDB1 ... | |||
TMPY-00302 | HIV-1 (group M, subtype A, isolate 92RW020) gp160 (gp120 subunit) Protein (His) | HIV | HEK293 |
The HIV-1 gp120 envelope protein, a glycoprotein that is part of the outer layer of the virus, is an essential component in the multi-tiered viral entry process. It presents itself as viral membrane spikes consisting of ... | |||
TMPY-04150 | HIV-p51/RT-p51 (group M, subtype B (isolate HXB2) Gag-Pol polyprotein Protein (His) | HIV | E. coli |
TMPY-04161 | HIV-p66/RT-p66 (group M, subtype B (isolate HXB2) Gag-Pol polyprotein Protein (His) | HIV | E. coli |
TMPY-01226 | CD4 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is a glycoprotein expre... | |||
TMPY-05384 | CD4 Protein, Human, Recombinant (hFc) | Human | HEK293 |
T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is a glycoprotein expre... | |||
TMPY-01032 | CD299 Protein, Human, Recombinant (hFc) | Human | HEK293 |
C-type lectin domain family 4, member M, also known as DC-SIGNR and CLEC4M, is a type II integral membrane protein that is 77% amino acid identical to DC-SIGN, an HIV gp120-binding protein. Though the encoded gene locate... | |||
TMPY-00772 | DC-SIGN Protein, Human, Recombinant (hFc) | Human | HEK293 |
Dendritic cell (DC)-specific intercellular adhesion molecule 3 (ICAM-3) grabbing nonintegrin (DC-SIGN), also known as CD209, is a type II transmembrane protein on DCs with a C-type lectin extracellular domain, is capable... | |||
TMPY-01400 | CD4 Protein, Human, Recombinant (His) | Human | HEK293 |
T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is a glycoprotein expre... | |||
TMPY-01209 | IL-7R alpha/CD127 Protein, Human, Recombinant (His) | Human | HEK293 |
Interleukin 7 Receptor alpha (IL-7RA), also known as CD127, is a 75 kDa hematopoietic receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7 receptor alp... | |||
TMPY-00635 | IL-7R alpha/CD127 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Interleukin 7 Receptor alpha (IL-7RA), also known as CD127, is a 75 kDa hematopoietic receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7 receptor alp... | |||
TMPY-01012 | P4HB Protein, Human, Recombinant (His) | Human | HEK293 |
Protein disulfide-isomerase, also known as Cellular thyroid hormone-binding protein, Prolyl 4-hydroxylase subunit beta, p55 and P4HB, is a peripheral membrane protein that belongs to the protein disulfide isomerase famil... | |||
TMPY-00586 | CLEC-2 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
CLEC1B, also known as CLEC2, is a C-type lectin-like receptor expressed in myeloid cells and NK cells. Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 and NKG2D, ... | |||
TMPY-00695 | I-309 Protein, Human, Recombinant (hFc) | Human | HEK293 |
CCL1 or chemokine (C-C motif) ligand 1, also known as I-309 or TCA-3, is a member of the chemokine (C-C motif) ligand family. The C-C chemokines have two cysteines nearby the amino terminus. There have been at least 27 d... | |||
TMPY-01686 | B2M/beta 2-Microglobulin Protein, Human, Recombinant (His) | Human | HEK293 |
B2M, also known as β2-Microglobulin or CDABP0092, is a component of MHC class I molecules found expression in all nucleated cells (excludes red blood cells). The major function of MHC class I moleculesis is to display fr... | |||
TMPY-00996 | PD-1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr... | |||
TMPY-05079 | PD-1 Protein, Human, Recombinant (mFc) | Human | HEK293 |
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr... | |||
TMPY-04898 | PD-1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr... | |||
TMPY-05395 | PD-1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr... | |||
TMPY-01442 | DMBT1 Protein, Human, Recombinant (His) | Human | HEK293 |
Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB d... | |||
TMPY-05260 | PD-1 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr... | |||
TMPY-04342 | PD-1 Protein, Canine, Recombinant (His) | Canine | HEK293 |
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr... | |||
TMPY-00897 | PD-1 Protein, Human, Recombinant (His) | Human | HEK293 |
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr... | |||
TMPY-05815 | PD-1 Protein, Canine, Recombinant (His & Avi), Biotinylated | Canine | HEK293 |
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr... | |||
TMPY-00767 | Cystatin C Protein, Human, Recombinant (His) | Human | HEK293 |
Cystatin C, also known as Cystatin-3 (CST3) is a secreted type 2 cysteine protease inhibitor synthesized in all nucleated cells, has been proposed as a replacement for serum creatinine for the assessment of renal functio... | |||
TMPY-02457 | IL-2 Protein, Rat, Recombinant | Rat | E. coli |
Interleukin-2, also known as a T-cell growth factor, TCGF, Aldesleukin, and IL2, is a secreted protein that belongs to the IL-2 family. Interleukin-2 / IL-2 was the first interleukin molecule to be discovered. Interleuki... | |||
TMPY-02788 | IL-2 Protein, Mouse, Recombinant | Mouse | E. coli |
Interleukin-2, also known as a T-cell growth factor, TCGF, Aldesleukin, and IL2, is a secreted protein that belongs to the IL-2 family. Interleukin-2 / IL-2 was the first interleukin molecule to be discovered. Interleuki... | |||
------------------------ More ------------------------ |
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A unique collection of 1040 anti-virus compounds effective for new anti-virus drugs high throughput screening and high content screening; | |||
L1720 | Nucleotide Compound Library | 337 compounds | |
A unique collection of 337 nucleoside and nucleotide analogues, can be used for research and development of anti-viral, anti-tumor, anti-fungal, and anti-depressive drugs; | |||
L1800 | Anti-Infection Compound Library | 2977 compounds | |
A unique collection of 2977 anti-infective compounds including anti-bacterial, anti-fungi, anti-Human Cytomegalovirus (HCMV), anti-HIV, anti-SARS, anti-influenza, etc; | |||
L9420 | Exosome Compound Library | 80 compounds | |
80 exosome-related compounds that can be used for high-throughput and high-content screening. | |||
L9400 | PPI Inhibitor Library | 490 compounds | |
A unique collection of 490 PPI-related compounds for drug screening; | |||
L1100 | Protease Inhibitor Library | 344 compounds | |
A unique collection of 344 protease and proteasome inhibitors for research in chemical genomics, and drug screening; | |||
L7600 | Chemokine Inhibitor Library | 59 compounds | |
A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening; |