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Results for "

1,11b dihydro 11b hydroxymedicarpin

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    1394
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    89
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    22
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    178
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1,11b-Dihydro-11b-hydroxymedicarpin
TN2478210537-04-5
1,11b-Dihydro-11b-hydroxymedicarpin is a natural product from Derris robusta.
  • $698
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Cyanosafracin B
T2228696996-50-8
Cyanosafracin B (Cyanoquinonamine) is a compound which can be used in the synthesis of ecteinascidin ET-743 (an antitumor chemotherapy drug).
  • $70
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Rhodamine B
T797581-88-9
Rhodamine B (Brilliant Pink B) is used as a tracer dye in water to determine the rate and direction of flow and transport.
  • $33
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Hygromycin B
T102231282-04-9
Hygromycin B (Hygrovetine) is an aminoglycoside antibiotic that inhibits protein synthesis by interfering with translocation and causing mistranslation of the 70S ribosome. Hygromycin B can be used to screen prokaryotic or eukaryotic cells transfected with hph or hyg resistance genes.
  • $48
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TargetMol | Citations Cited
Amphotericin B
T10671397-89-3
Amphotericin B (NSC-527017) is a polyene antifungal agent with broad-spectrum activity against many fungal species. Amphotericin B irreversibly binds to ergosterol and disrupts the integrity of cell membranes, resulting in antifungal activity.
  • $31
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Aloin(mixture of A&B)
T56808015-61-0
ALOIN Inhibits Interleukin (IL)-1β-Stimulated IL-8 Production in KB Cells.
  • $39
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Ginkgolide B
T275115291-77-7
Ginkgolide B (BN-52021) is a PAFR antagonist(IC50=3.6 μM) isolated from Ginkgo biloba.
  • $57
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TargetMol | Citations Cited
Kukoamine B mesylate
T7026L1375179-86-4In house
Kukoamine B mesylate is a novel cationic alkaloid derived from dermatophytes with antioxidant activity, inhibits LPS internalization in Kupffer and RAW 264.7 cells, and can be used to study acute inflammation and diabetes.
  • $195
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Urolithin B
T132651139-83-9
Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropical fruits, and medicinal herbs. Urolithin B inhibits NF-κB activity by reducing the phosphorylation and degradation of IκBα, and suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphorylation of AMPK. Urolithin B is also a regulator of skeletal muscle mass. Urolithin B has anti-inflammatory and antioxidant effects.
  • $39
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Macranthoside B
T5787146100-02-9
Macranthoside B Iis a natural product isolated from Flos Lonicerae, possesses anti-bacterial activity.
  • $46
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Pygmaniline B
TN715056402-79-0
Pygmaniline B (1,3-bis(2,4-dimethoxyphenyl)urea) is a marine derived natural products found in Lichina pygmaea.
  • $195
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Dihydroarteannuin B
TN677787206-33-5
Dihydroarteannuin B ((3R)-dihydroarteannuin B) is a natural Dihydroarteannuin.
  • $133
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Coreoside B
TN70941580464-83-0
Coreoside B is isolated from coreoside and showed weak antimicrobial activity against S. aureus and B. anthracis.
  • $148
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Cowaxanthone B
TN1530212842-64-3
Cowaxanthone B is a new tetraoxoanthrone isolated from the fruit of Garcinia cambogia.Cowaxanthone B has potential antibacterial activity.
  • $329
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Cephalandole B
TN7236915315-44-5
cephalandole B, an indole alkaloid isolated from cyanide, significantly inhibited IL-17A gene expression and suppressed IL-17A luciferase reporter in Jukat cells in a dose-dependent manner.
  • $195
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Sculponeatin B
TN497085287-60-1
Sculponeatin A is a natural product from Rabdosia amethystoides.
  • $898
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Aloinoside B
TN691011006-91-0
Aloinoside B (11-o-Rhamnosylaloin B) is a glycoside from aloe vera.
  • $195
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Lophanthoidin B
TN4451120462-42-2
Lophanthoidin B is a natural product isolated from the herbs of Rabdosia lophanthoides.
  • $195
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Magnoloside B
TN7134116872-05-0
Magnoloside B, a phenylethanol glycoside from the fruit of Magnolia officinalis, is an α-glucosidase inhibitor with protective effects against free radical-induced oxidative damage and can be used in cancer research.
  • $195
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Maoecrystal B
TN449496850-29-2
Maoecrystal B is a diterpenoid isolated from the leaves of Isodon eriocalyx var.
  • $745
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Bryonamide B
TN14575942-25-6
Bryonamide B is a cucurbitane triterpene that can be extracted from Bryonia aspera.
  • $64
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Praeruptorin B
T4S142173069-28-0In house
Praeruptorin B is an inhibitor of sterol regulatory element-binding proteins (SREBPs) and can significantly up-regulate CYP3A4 expression and activity via the PXR-mediated pathway.
  • $86
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Protosappanin B
T6S1780102036-29-3
1. Protosappanin B (Q-100961) significantly increases cell viability, inhibits cell apoptosis and up-regulates the expression of growth-associated protein 43. 2. Protosappanin B induces the degradation of p53 protein, via activation of a MDM2-dependent ubiquitination process.
  • $67
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TargetMol | Citations Cited
Oroxin B
T3780114482-86-9
Oroxin B (Hypocretin-2) has antioxidant activity.
  • $110
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Epimedin B
T6S2146110623-73-9
1. Epimedin B (Epmedin B) has potential activity against osteoporosis by stimulating osteoblasts.
  • $130
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Oenothein B
TN6732104987-36-2
Oenothein B is a specific inhibitor of poly(ADP-ribose) glycohydrolase. Oenothein B shows antioxidant, anti-inflammatory, antifungal, anti-HCV, and antitumor properties.
  • $298
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Cytosporone B
T3976321661-62-5
Cytosporone B (Dothiorelone G) is a naturally occurring agonist for the nuclear receptor Nur77 (IC50 = 0.278 nM). Activation of Nur77 with cytosporone B induces the expression of Nur77-dependent genes, including the gene for Nur77 itself. Signaling through Nur77 induces apoptosis in cancer cells and retards xenograft tumor growth. It also induces genes related to gluconeogenesis and decreases atherosclerosis progression in mice fed a high fat and high cholesterol diet. Cytosporone B is brain penetrant and aggravates early brain injury in rats when given (13 mg/kg intraperitoneally) after experimentally-induced subarachnoid hemorrhage. Cytosporone B also has antibacterial properties.
  • $39
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TargetMol | Citations Cited
Flavokawain B
T6S07351775-97-9
1. Flavokawain B (Flavokavain B) has potent anti-inflammatory activity, can significantly inhibit production of NO and PGE2 in LPS-induced RAW 264.7 cells. 2. Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK/NF-κB and MAPK signaling pathways. 3. Flavokawain B induces apoptosis, has the potential usefulness of FKB for prevention and treatment of hormone-refractory prostate cancer in an adjuvant setting. 4. Flavokawain B acts through ROS generation and GADD153 up-regulation to regulate the expression of Bcl-2 family members, thereby inducing mitochondrial dysfunction and apoptosis in HCT116 cells.
  • $67
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TargetMol | Citations Cited
Cucurbitacin B
T34046199-67-3
Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells. It inhibited AKT signaling activation through up-regulation of PTEN. Cucurbitacin B is an effective inhibitor of HIF-1 and provide new perspectives into the mechanism of its anticancer activity. Cucurbitacin B inhibits proliferation and induces apoptosis via STAT3 pathway inhibition in A549 lung Y cells.
  • $44
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TargetMol | Citations Cited
Salvianolic acid B
T2727115939-25-8
Salvianolic acid B (Dan Shen Suan B), a natural product from Salvia miltiorrhiza, is a water-soluble antioxidant. Salvianolic acid B has antiplatelet aggregation, anticoagulant, and antithrombotic effects, and is commonly used in the study of microcirculatory disorders.
  • $60
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TargetMol | Citations Cited
Torachrysone-8-O-b-D-glucoside
TN227764032-49-1
Torachrysone-8-O-b-D-glucoside exhibits alpha-glucosidase inhibitory activities and may be utilized for managing type 2 diabetes.
  • $113
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Polyporusterone B
TN6909141360-89-6
Polyporusterone B ((1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R)-2,3-dihydroxy-6-methyl-5-methylideneheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one) is a triterpene carboxylic acid isolated from Polyporus umbellatus Fries known as pentahydroxy bile acids, alcohols, and derivatives. Polyporusterone B Polyporusterone B has an inhibitory effect on free radical-induced lysis of red blood cells (hemolysis).
  • $52
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Podecdysone B
T1382222612-27-7
β-Gentiobiose is a natural oligosaccharide that promotes fruit ripening.
  • $107
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Kansuinine B
T4066057685-46-8
Kansuinine B inhibits Stat3 activation induced by IL-6. Kansuinine B exhibits anti-viral activity and could be used in COVID-19 research.
  • $322
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Schisandrol B
T6S191758546-54-6
1. Schisandrol B (Besigomsin) may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated NF-κB and MAPKs signaling pathways. 2. Schisandrol B has anti-inflammatory property, potentially result from the inhibition of COX-2, iNOS, IL-6, TNF-α and NO through the down-regulation of RIP2 and NF-κB activation. 3. Schisandrol B induces marked protective effects against hepatic and renal injury induced by CCl(4) exposure through differential regulation of the MAPK signal transduction pathway. 4. Schisandrol B significantly inhibits cell proliferation in a dose-dependent manner, due to cell cycle arrest in the G1 phase with the downregulation of cyclin D1 expression and Retinoblastoma (RB) phosphorylation.
  • $65
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Licochalcone B
T4S035058749-23-8
1. Licochalcone B (LCB) inhibits the proliferation of human malignant bladder cancer cell lines (T24 and EJ) in vitro and antitumor activity in vivo in MB49 (murine bladder cancer cell line) tumor model. 2. LCB and Licochalcone D(LCD) significantly reduce
  • $48
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HYPOCRELLIN B
T5780123940-54-5
HYPOCRELLIN B are photosensitive pigments isolated from Hypocrella bambusae Sacc. Hypocrellin B causes DNA strand breakage, induces apoptosis in ovarian cancer cells, and inhibits proliferation of Staphylococcus by increasing ROS levels, and damaging cell
  • $64
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(S)-b-aminoisobutyric acid
T73574249-19-8
(S)-β-aminoisobutyric acid is a non-protein amino acid derived from the catabolism of valine and thymine.
  • $50
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Camelliaside B
T3853131573-90-5
Camelliaside B possesses deglycosylation activity.
  • $109
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Taccalonolide B
TN2256108885-69-4
Taccalonolide B is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug-resistance protein (MRP7). Taccalonolide B inhibits growth of SK-OV-3 cells with an IC50 of 208 nM.
  • $48
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Gardenin B
TN16752798-20-1
Gardenin B exhibits superior antiproliferative activity against lung, breast, colon, hepatic and leukaemia cell lines as well as in keratinocytes .
  • $68
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Segetalin B
TMA1644164991-89-3
Segetalin B is a natural product from Vaccaria segetalis (Neck.) Garcke, has estrogen-like activity.
  • $32
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Aloin B
T5S117728371-16-6
Aloin B (Isobarbaloin) is an isomer of aloin.1. The extract of A. vera and its active ingredient aloin cause melanin aggregation leading to skin lightening via alpha adrenergic receptor stimulation, the result opens new vistas for the use of A. vera regarding its clinical application as a new nontoxic melanolytic agent for the treatment of hyperpigmentation. 2. Dietary supplementation of aloe components (aloin, aloesin and aloe-gel) can ameliorate intestinal inflammatory responses in a 3% dextran sulfate sodium (DSS)-induced ulcerative colitis rat model, in particular, aloesin is the most potent inhibitor.
  • $40
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Hederasaponin B
T334536284-77-2
Hederasaponin B (Hederacoside B) has antiviral activity, via inhibiting the viral VP2 protein expression and blocking viral capsid protein synthesis.
  • $64
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Demethoxydeacetoxypseudolaric acid B
TN382082508-36-9
Demethoxydeacetoxypseudolaric acid B's the metabolic reaction of TDA in vivo is mainly occurred in blood and contributes to be the hydrolysis of plasma esterase to ester bond, as well as the glucosylation reaction.
  • $97
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Ganoderic acid B
TN105981907-61-1
Ganoderic acid B is a chemical marker in quality control of G. lucidum and related products. Ganoderic acid B-containing herbs has potential influence towards therapeutic window of trifluoperazine.Ganoderic acid B has antinociceptive effect
  • $97
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Aureusimine B
T37753170713-71-0
Aureusimine B, also known as phevalin, is a natural pyrazinone produced by certain fungi and by Staphylococcus spp., including S. aureus. Its synthesis appears to be initiated by a conserved nonribosomal peptide synthetase that creates a dipeptide (phenylalanine-valine) aldehyde, which then undergoes cyclization and oxidation. Aureusimine B inhibits calpain in a casein hydrolysis assay (IC50 = 1.3 μM), contributes to S. aureus infection in mice, and alters human keratinocyte gene expression.
  • $148
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Ciwujianoside B
T3344114902-16-8
Ciwujianoside B (acanthopanax senticosides B) is the main component of Acanthopanax, can relieve fatigue, enhance memory, and improve human cognition.
  • $76
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Aristolochic acid B
T7031475-80-9
Aristolochic acid B (Aristolochic Acid II) is one of the major components of the carcinogenic plant extract aristolochic acid, is known to be mutagenic and to form DNA adducts in vitro and in vivo, Aristolochic acid B shows more carcinogenic risk than aristolochic acid I, and this may be, at least partly, the result of its increased levels in kidney and plasma.
  • $72
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Huperzine B
T2S1720103548-82-9
1. Huperzine-B is a efficient inhibitor of human brain AChE. 2. Huperzine-B can enhance ognitive and protect neuro, may be potentially new drug candidates for Alzheimer's disease therapy.
  • $61
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