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Search Results for " tnf "

327

Compounds

133

Natural Products

517

Recombinant Proteins

5

Libraries

Cat No. Product Name Synonyms Targets
T19584L TNF-α (31-45), human acetate TNF-α (31-45), human acetate(144796-71-4 free base) Others
TNF-α (31-45), human acetate is a peptide of tumor necrosis factor-α.
T77494 TNF-α-IN-9 TNF
TNF-α-IN-9 is an NDM-1 inhibitor-3 analog and is a TNF-α inhibitor.TNF-α-IN-9 shows low inhibitory activity.
T83628 TNF/IFNγ-IN-1 Antioxidant , TNF , COX
TNF/IFNγ-IN-1 (TGA) is a dual inhibitor of TNF and IFN-γ. TNF/IFNγ-IN-1 has potential antioxidant and anti-inflammatory activities for neurodegenerative diseases such as Alzheimer.
T36127 TNF-α Antagonist
TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction with the receptor. By blocking the TNF receptor ligand contact sit...
T4637 R-7050 TNF-α Antagonist III TNF
R-7050 (TNF-α Antagonist III) is a tumor necrosis factor receptor (TNFR) antagonist with greater selectivity toward TNFα.
T40321 TNF-α-IN-6
TNF-α-IN-6 is an orally efficacious allosteric inhibitor of TNFα ( K D = 6.8 nM).
T36097 TNF-α-IN-2
TNF-α-IN-2 is a highly potent and orally bioavailable inhibitor of tumor necrosis factor alpha (TNFα), exhibiting an IC50 of 25 nM in the HTRF assay. It exerts its inhibitory effects by inducing conformational changes in...
T13175 TNF-α-IN-1 TNF
TNF-α-IN-1 is a TNF-α inhibitor.
TP1626 TNF-α (46-65), human
Human TNF alpha (46-65) peptide.
TQ0129 TNF Protease Inhibitor 2 TAPI-2 MMP
TAPI-2 is a broad-spectrum inhibitor of MMP (IC50: 20 μM), tumour necrosis factorα-converting enzyme (TACE) and a disintegrin and metalloproteinase (ADAM).
TP1636 TNF-α (31-45), human TFA (144796-71-4 free base) TNF-α (31-45), human TFA
TNF-α (31-45), human (TFA) is a peptide of tumor necrosis factor-α.
TP1479 TNF-α (10-36), human (TFA) (144796-70-3 free base) TNF-α (10-36), human (TFA)
TNF-α (10-36), human (TFA) is a peptide of human TNF-α.
T19584 TNF-α (31-45), human Others
TNF-α (31-45), human is a peptide of tumor necrosis factor-α.
TP1537 TNF-α (10-36), human
TNF-α (10-36), human is a potent pro-inflammatory cytokine involved in the acute phase stress response.
TP1669 TNF-α (46-65), human TFA (144796-72-5 free base) TNF-α (46-65), human TFA
TNF-α (46-65), human (TFA) is a peptide of human TNF-α.
T79025 TNF-α-IN-10
TNF-α-IN-10 (compound 8a) acts as an inhibitor of IL-6 and TNF-α, demonstrating anti-inflammatory activity [1].
T78730 TNF-α-IN-11
TNF-α-IN-11 (Compound 10) is a TNF-α inhibitor exhibiting a dissociation constant (K D) of 12.06 μM. By binding to TNF-α, it impedes TNF-α-induced caspase activation and the NF-κB signaling pathway. Additionally, it supp...
T80973 TNF-α-IN-8
TNF-α-IN-8 (compound I-42) is an isoindole-imide-based inhibitor of tumor necrosis factor-alpha (TNF-α) with applications in researching various diseases including cancer, heart disease, osteoporosis, and autoimmune diso...
T76026 TNF-α (31-45), human TFA
TNF-α (31-45), human (TFA) is a peptide of tumor necrosis factor-α. Tumour necrosis factor alpha (TNF alpha) is an inflammatory cytokine that induces necrosis or apoptosis [1] .
T76029 TNF-α (46-65), human TFA
TNF-α (46-65), human (TFA) is a peptide of human TNF-α.
T78272 Anti-Mouse TNF alpha Antibody (TN3-19.12)
Anti-Mouse TNF alpha Antibody is a rat-derived IgG inhibitor targeting mouse TNF alpha.
T77778 KP-457 TNF‐α‐converting enzyme
KP-457 (TNF-α-converting enzyme) is a selective inhibitor of ADAM17, with an IC50 value of 11.1 nM/L in cell-free assays. The compound can also cleave a variety of molecules, including GPIbα, GPV and TNF-α.
T8692 (Rac)-Benpyrine TNF
(Rac)-Benpyrine is a potent and orally active inhibitor of TNF-α.
T78434 Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human) TFA
Mca-(endo-1α-Dap(Dnp))-TNF-α(-5 to +6) amide (human) TFA is a peptide that functions as a fluorescence resonance energy transfer (FRET)-based substrate, with its activity determined by the change in fluorescence intensit...
T81838 Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human)
Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human) is a peptide utilized as a fluorescence resonance energy transfer (FRET) based substrate for proteolytic activity assays, wherein the cleavage-induced change in f...
T4319 Hispidol (Z)-Hispidol TNF
Hispidol ((Z)-Hispidol) ((Z)-Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colon epithelial cells with an IC50 of 0.50 μM.
T14848 C 87 Others , TNF
C 87 is a small-molecule TNF-α inhibitor. C 87 directly binds to TNFα, potently inhibits TNF-α-induced cytotoxicity (IC50 = 8.73 μM), and effectively blocks TNF-α-triggered signaling activities.
T8477 IQ-3 JNK
IQ3 is a selective inhibitor of JNK3(JNK3, JNK1 and JNK2 with Kd of 66 nM, 240 nM and 290 nM, respectively). IQ 3 inhibits NF-κB/AP1 transcriptional activity in THP1-Blue cells with IC50 of 1.4 μM, also inhibits TNF-α an...
T40423 L48H37
L48H37 is a chemically stable analog of Curcumin. It exhibits potent inhibitory properties against myeloid differentiation protein 2 (MD2), acting as a specific inhibitor. Its mechanism involves inhibiting the interactio...
T7495 Hexa-D-arginine Others
Hexa-D-arginine is an inhibitor of furin,blocks the activation of Pseudomonas aeruginosa exotoxin A in vivo.
T2343 AS601245 JNK
AS601245 is an inhibitor of the c-Jun NH2-terminal kinase (JNK), with neuroprotective properties.
T11096 DRI-C21045 NF-κB
Dri-c21045 showed concentration-dependent inhibition of NF- B activation and all CD40L induced by B cell proliferation. IC50 was 17.1 M and 4.5 M, respectively.Dri-c21045 is an effective selective inhibitor of CD40-CD40L...
T8727 TH1020 TLR , Antibacterial
TH1020 is a novel Inhibitor of Toll-Like Receptor 5 (TLR5)/Flagellin Complex with promising activity (IC50 =0.85±0.12 μm) and specificity.
T9921 Infliximab TNF
Infliximab is a humanized antibody against tumor necrosis factor α TNF-α) that is used in the treatment of Crohn's disease and rheumatoid arthritis.
TQ0181 Resatorvid CLI-095,TAK-242 TNF , TLR , Autophagy , Interleukin
Resatorvid (TAK-242) (TAK-242) is a selective inhibitor of Toll-like receptor 4 (TLR4). Resatorvid inhibits IL-6, TNF-R and NO production (IC50s: 1.3 nM, 1.9 nM, and 1.8 nM).
T2065 Bioymifi DR5 Activator Apoptosis , TNF
Bioymifi (DR5 Activator) is a novel and potent small-molecule activator of the TRAIL receptor DR5 in human cancer cells.
T13231L Trovafloxacin mesylate Others , DNA/RNA Synthesis , Topoisomerase , Antibacterial
Trovafloxacin is a broad-spectrum fluoroquinolone antibiotic that inhibits the activity of DNA gyrase and topoisomerase IV, enzymes involved in DNA replication. It also acts as an effective and specific inhibitor of the ...
T13951 UCB-9260 TNF
UCB-9260 inhibits TNF signaling by stabilizing an asymmetric form of the trimer.
T8798 MSA-2 STING
MSA-2 is a potent and orally available non-nucleotide STING agonist.
T13018 SU3327 halicin JNK
SU3327 (halicin) is a potent, selective and substrate-competitive inhibitor of JNK(IC50 of 0.7 μM).
T12997 SR-318 p38 MAPK , TNF
SR-318 is a potent and highly selective inhibitor of p38 MAPK(IC50s of 5 nM, 32 nM and 6.11 μM for p38α, p38β and p38α/β, respectively), has anti-cancer and anti-inflammatory activity.
T22115 SM-7368 NF-κB
The NF-κB Activation Inhibitor III, controls the biological activity of NF-κB. It is primarily used for Inflammation/Immunology applications.
T7001 TIC10 ONC-201 Apoptosis , TNF
TIC10 (ONC-201) inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacokinetics. Phase 1/2.
T9028 STING-IN-2 C-170 STING
STING-IN-2 (C-170) is a potent and covalent inhibitor of STING. C-170 efficiently inhibits both mouse STING (mmSTING) and human STING (hsSTING). It can be used for autoinflammatory disease research.
T4328 OSS_128167 SIRT6-IN-1 HBV , Sirtuin
OSS_128167 (SIRT6-IN-1) is a specific SIRT6 inhibitor, and for SIRT6(IC50=89 μM), SIRT1(IC50=1578 μM) and SIRT2(IC50=751 μM).
T12493 PK68 Others , RIP kinase
PK68 is an effective and selective inhibitor of type II receptor-interacting kinase 1 (RIPK1, IC50 = 90 nM). PK68 can be used for research on the treatment of inflammatory disorders and cancer metastasis.
T3561 CPI1189 CPI-1189,REN-1189,CPI 1189 TNF
CPI1189 (REN-1189) is a TNF-a release inhibitor potentially for the treatment of sciatica and postherpetic neuralgia.
T7091 N-Formyl-Met-Leu-Phe fMLP,N-Formyl-MLF TNF
N-Formyl-Met-Leu-Phe (N-Formyl-MLF) (fMLF) is a synthetic peptide that acts as an agonist at formyl peptide receptors (FPR; Ki = 0.8 pM).
T13324 VUF11207 fumarate CXCR , Arrestin
VUF11207 fumarate is an agonist of CXCR7 and a high-potency ligand of CXCR7 (pKi: 8.1).
T6150 TAK-715 p38 MAPK , Casein Kinase , JNK
TAK-715 is a p38 MAPK inhibitor for p38α.

Compounds

TNF-α (31-45), human acetate
T19584L
Synonym: TNF-α (31-45), human acetate(144796-71-4 free base)
Target: Others
TNF-α-IN-9
T77494
Synonym:
Target: TNF
TNF/IFNγ-IN-1
T83628
Synonym:
Target: Antioxidant, TNF, COX
TNF-α Antagonist
T36127
Synonym:
Target:
R-7050
T4637
Synonym: TNF-α Antagonist III
Target: TNF
TNF-α-IN-6
T40321
Synonym:
Target:
TNF-α-IN-2
T36097
Synonym:
Target:
TNF-α-IN-1
T13175
Synonym:
Target: TNF
TNF-α (46-65), human
TP1626
Synonym:
Target:
TNF Protease Inhibitor 2
TQ0129
Synonym: TAPI-2
Target: MMP
TNF-α (31-45), human TFA (144796-71-4 free base)
TP1636
Synonym: TNF-α (31-45), human TFA
Target:
TNF-α (10-36), human (TFA) (144796-70-3 free base)
TP1479
Synonym: TNF-α (10-36), human (TFA)
Target:
TNF-α (31-45), human
T19584
Synonym:
Target: Others
TNF-α (10-36), human
TP1537
Synonym:
Target:
TNF-α (46-65), human TFA (144796-72-5 free base)
TP1669
Synonym: TNF-α (46-65), human TFA
Target:
TNF-α-IN-10
T79025
Synonym:
Target:
TNF-α-IN-11
T78730
Synonym:
Target:
TNF-α-IN-8
T80973
Synonym:
Target:
TNF-α (31-45), human TFA
T76026
Synonym:
Target:
TNF-α (46-65), human TFA
T76029
Synonym:
Target:
Anti-Mouse TNF alpha Antibody (TN3-19.12)
T78272
Synonym:
Target:
KP-457
T77778
Synonym: TNF‐α‐converting enzyme
Target:
(Rac)-Benpyrine
T8692
Synonym:
Target: TNF
Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human) TFA
T78434
Synonym:
Target:
Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human)
T81838
Synonym:
Target:
Hispidol
T4319
Synonym: (Z)-Hispidol
Target: TNF
C 87
T14848
Synonym:
Target: Others, TNF
IQ-3
T8477
Synonym:
Target: JNK
L48H37
T40423
Synonym:
Target:
Hexa-D-arginine
T7495
Synonym:
Target: Others
AS601245
T2343
Synonym:
Target: JNK
DRI-C21045
T11096
Synonym:
Target: NF-κB
TH1020
T8727
Synonym:
Target: TLR, Antibacterial
Infliximab
T9921
Synonym:
Target: TNF
Resatorvid
TQ0181
Synonym: CLI-095,TAK-242
Target: TNF, TLR, Autophagy, Interleukin
Bioymifi
T2065
Synonym: DR5 Activator
Target: Apoptosis, TNF
Trovafloxacin mesylate
T13231L
Synonym:
Target: Others, DNA/RNA Synthesis, Topoisomerase, Antibacterial
UCB-9260
T13951
Synonym:
Target: TNF
MSA-2
T8798
Synonym:
Target: STING
SU3327
T13018
Synonym: halicin
Target: JNK
SR-318
T12997
Synonym:
Target: p38 MAPK, TNF
SM-7368
T22115
Synonym:
Target: NF-κB
TIC10
T7001
Synonym: ONC-201
Target: Apoptosis, TNF
STING-IN-2
T9028
Synonym: C-170
Target: STING
OSS_128167
T4328
Synonym: SIRT6-IN-1
Target: HBV, Sirtuin
PK68
T12493
Synonym:
Target: Others, RIP kinase
CPI1189
T3561
Synonym: CPI-1189,REN-1189,CPI 1189
Target: TNF
N-Formyl-Met-Leu-Phe
T7091
Synonym: fMLP,N-Formyl-MLF
Target: TNF
VUF11207 fumarate
T13324
Synonym:
Target: CXCR, Arrestin
TAK-715
T6150
Synonym:
Target: p38 MAPK, Casein Kinase, JNK
1 2 3 4 5 6 7
Cat No. Product Name Synonyms Targets
T6S2099 Geraniin Antioxidant , TNF
1. Geraniin has a protective effect against OVX-induced rat osteoporosis. 2. Geraniin has cytotoxic activity towards cancer cells in vitro and in vivo. 3. Geraniin exerts inhibitory effects on osteoclast differentiation ...
T6S0630 Hypaconitine P450 , TNF
Hypaconitine, an active and highly toxic constituent derived from Aconitum species, has anti-inflammatory activity, is widely used to treat rheumatism.
T4S0217 HOMOPLANTAGININ TNF , NF-κB
Homoplantaginin is a flavonoid from a traditional Chinese medicine Salvia plebeia,it has a protective and therapeutic effect on hepatocyte injury and shows potent inhibitory activities against influenza.
T6S1572 Sauchinone ERK , p38 MAPK , NF-κB
1. Sauchinone is a useful adjunctive treatment for bacterial infection. 2. Sauchinone, an active lignan found in Saururus chinensis, to regulate the activation of HSCs, to prevent liver fibrosis, and to inhibit oxidative...
T6S1597 Mulberroside A TNF , Tyrosinase , Interleukin
1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosylation of Mulberroside A resulted in enhanced inhibition of...
T2893 Muscone 3-Methylcyclopentadecanone,Methylexaltone MMP , TNF , NF-κB , NOD-like Receptor (NLR) , P-gp , Interleukin
Muscone (3-Methylcyclopentadecanone) is an organic compound that is the primary contributor to the odor of musk.
T6S0627 Mesaconitine TNF
1. Mesaconitine has antiinflammatory activity. 2. Mesaconitine has antinociceptive activity through cyclic AMP and stimulation of the central β-adrenergic system.
T2879 Fisetin TNF , Sirtuin , PPAR
Fisetin is a natural flavonol extracted from Rhus succedanea L that is structurally and functionally related to kaempferol, can modulate sirtuins,with antioxidant, anticancer, neuroprotection effects.
T3893 Forsythoside B TNF , NF-κB
Forsythoside B binds to LPS and reduces the biological activity of serum LPS, and inhibits NF-κB activation. Forsythoside B inhibits the inflammatory response and has antioxidant properties. Potent neuroprotective effect...
T4S0227 Sinensetin Pedalitin permethyl ether TNF , PGE Synthase
Sinensetin (Pedalitin permethyl ether) is a methylated flavone found in certain citrus fruits. pocess potent antiangiogenesis and anti-inflammatory, sinensetin enhances adipogenesis and lipolysis.
T15686 L-741626 3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole Dopamine Receptor
L-741626 (3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole) is a selective antagonist of D2 dopamine receptor (Ki: 2.4, 100, and 220 nM for human D2, D3 and D4 receptors respectively).
T4S1521 1,4-Dicaffeoylquinic acid HIV Protease
1,4-Dicaffeoylquinic acid has antioxidant activity.1,4-Dicaffeoylquinic acid is a potent and highly selective class of HIV-1 integrase inhibitors, inhibitsHIV-1 replication in MT-2 cell culture at non-toxic concentration...
T2720 Ginsenoside Rc Panaxoside Rc Others , TNF , GABA Receptor , Interleukin
Ginsenoside Rc (Panaxoside Rc) is one of the ginsenosides from Panax ginseng, inhibits the expression of TNF-α and IL-1β.
T7786 Tryptanthrin DNA gyrase
Tryptanthrin is a natural DNA gyrase inhibitor.
TN6796 2'-FUCOSYLLACTOSE 2'-Fucosyl-D-lactose Others
2'-FUCOSYLLACTOSE (2'-Fucosyl-D-lactose) is a fucose-containing oligosaccharide.
T2S0843 Negletein 7-O-Methylbaicalein,Baicalein-7-methylether IL Receptor , TNF , NOS , Interleukin
1. Negletein (7-O-Methylbaicalein) has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. 2. Negletein as a neuroprotectant enhances the action of nerve growth factor and induces n...
T2A2481 Taurochenodeoxycholic Acid Chenodeoxycholyltaurine,TCDCA,Chenyltaurine,Taurochenodeoxycholate,12-Deoxycholyltaurine Apoptosis , TNF , Caspase , Endogenous Metabolite
Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.
TN2130 Manghaslin Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside AChE , Glucosidase
Manghaslin (Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside) has considerable α-glucosidase inhibitory activity, illustrating the anti-diabetic potential of phenolic-rich litchi pulp extracts. Manghaslin also shows inhibito...
T2P2870 Damascenone trans-damascenone,Beta-Damascenone Others , NF-κB , Endogenous Metabolite
Damascenone (trans-damascenone) is a norisoprenoid ketone mainly found in red wines. It occurs naturally in tomato and grapes.
T2758 Madecassic acid 6-Deoxy-L-Galactose,L-Fucose,Brahmic acid,L-fucopyranose Others , TNF , COX , NO Synthase , Interleukin
Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.
T2794 Astilbin Neoastilbin,Taxifolin 3-O-rhamnoside,Isoastilbin,Taxifolin 3-rhamnoside,Neoisoastilbin TNF , NF-κB , Nrf2
Astilbin (Neoastilbin) is actions Flavonoid phytochemical found in St. John′s wort and Traditional Chinese Medicine herbal preparations.
T13808 P-Coumaric Acid Ethyl Ester Ethyl (E)-p-hydroxycinnamate,Ethyl trans-4-hydroxycinnamate Others , Drug Metabolite
p-Coumaric Acid Ethyl Ester (Ethyl (E)-p-hydroxycinnamate) is the ethyl ester of p-Coumaric acid. p-Coumaric Acid is a common dietary polyphenol and also a potent immunosuppressive agent in treating autoimmune inflammato...
TN2215 Taurochenodeoxycholic acid sodium Sodium taurochenodeoxycholate Apoptosis , Endogenous Metabolite
Taurochenodeoxycholic acid sodium (Sodium taurochenodeoxycholate) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid sodium induces apoptosis and shows obvious anti-inflammatory and...
T6S1538 Neochlorogenic acid trans-5-O-Caffeoylquinic acid,Neochlorogenate,5-O-Caffeoylquinic acid TNF , NF-κB , COX , Antibacterial , Interleukin
Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.
TN1291 7,3',4'-Tri-O-methylluteolin 5-Hydroxy-3',4',7-trimethoxyflavone TNF , COX , Interleukin
7,3',4'-Tri-O-methylluteolin (5-Hydroxy-3',4',7-trimethoxyflavone) has anti-inflammatory, antibacterial and antifungal activities, it also shows moderate antitrypanosomal activity with MIC value of 19.0 ug/ml
T1125 Shikonin NSC 252844,Isoarnebin 4,(+)-Shikonin,Alkanna Red,C.I. 75535,Anchusa acid TNF , NF-κB , Chloride channel , HIV Protease , PKM
Shikonin (Anchusa acid) is an TMEM16A chloride channel inhibitor (IC50: 6.5 μM). Shikonin is also a selective PKM2 inhibitor and can also suppress activation of the NF-κB pathway and inhibit TNF-α. Shikonin decreases exo...
TCS2170 2,5-Dihydroxyacetophenone Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP ERK , NF-κB , Tyrosinase
1. 2,5-Dihydroxyacetophenone (Quinacetophenone) possess anti-anxiety, and neuroprotective qualities. 2. 2,5-Dihydroxyacetophenone (Quinacetophenone) reatment can induce a sustained activation of JNK, ERK1/2, and p38 MAPK...
T2932 Ginsenoside Rh1 Sanchinoside B2,Prosapogenin A2,20(S)-Ginsenoside Rh1,Sanchinoside Rh1 IL Receptor , TNF , Endogenous Metabolite , PPAR , Interleukin
Ginsenoside Rh1 (Sanchinoside B2) , one of the main constituents of Panax ginseng, exhibits anti-inflammatory effect.
T6S2140 β-Anhydroicaritin Anhydroicaritin,Beta-Anhydroicaritin MMP , Others , TNF , Interleukin
1. β-Anhydroicaritin exhibits immunosuppressive effect on the mouse macrophages stimulated by LPS. 2. β-Anhydroicaritin phytosomes can inhibit enhanced bone turnover induced by ovariectomy, improve BMD the biomechanical ...
T5779 MOSLOFLAVONE IL Receptor , Virus Protease , TNF , Antibacterial
MOSLOFLAVONE showed promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 0.71 μM and 7.8 μM, respectively.
TQ0218 Deoxyandrographolide 14-deoxyandrographolide IL Receptor , TNF
Deoxyandrographolide (14-deoxyandrographolide) potentiates NGF-induced neurite outgrowth. Deoxyandrographolide suppresses the production of proinflammatory mediators TNF-α and IL-6.
TN2539 1beta-Hydroxyalantolactone IL Receptor , TNF
1beta-Hydroxyalantolactone is a small molecular compound isolated from the flower head of the medicinal plant giant British flower, which can inhibit the expression of TNF-α, IL-17 and IFN-γ in cells, promote the secreti...
T8288 14-Deoxyandrographolide Apoptosis , Others
14-Deoxyandrographolide is a bioactive compound of Andrographis paniculata with hepatoprotective efficacy. It desensitizes hepatocytes to TNF-α-mediated apoptosis through the release of TNFRSF1A release.
T3889 Platycodin D Prostaglandin Receptor , AMPK
Platycodin D may stimulate TNF-α synthesis or inhibit degradation of TNF-α mRNA. Platycodin D (10/30 μM) suppresses prostaglandin E2 production in rat peritoneal macrophages stimulated by the protein kinase C activator 1...
TC0036 Compound Lup-20(29)-en-3-yl acetate IL Receptor , VEGFR , Others , TNF , COX
Lupeol acetate, a derivative of Lupeol, inhibits the progression of rheumatoid arthritis by downregulating TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B.
T3S1641 Esculentoside H TNF , NF-κB , JNK
Phytolaccaceae has anti-tumor activity, the mechanism may be related to the capacity of Esculentoside H for TNF release.
TN1520 Isoforskolin Coleonol B IL Receptor , TNF
Isoforskolin is derived from Coleus forskohlii and reduces the secretion of TNF-α, IL-1β, IL-6 and IL-8 in human mononuclear leukocytes. Isoforskolin can be used in studies about the treatment of Lyme arthritis.
T3887 Rosarin Others
Rosarin has anti-inflammatory and neuroprotective effects. Rosarin supresses the expression of the proinflammatory factors iNOS, IL-1 β, and TNF- α in the kidney and prefrontal cortex of brain in mice .
T0131 Cepharanthine NSC-623442 Apoptosis , TNF , HIV Protease , Autophagy
Cepharanthine (NSC-623442), a biscoclaurine alkaloid, suppresses tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and inhibits cytokine production.
TN1507 Clematichinenoside AR TNF , Autophagy
Clematichinenoside AR exerts anti-inflammatory and immunosuppressive properties, it has anti-arthritic effects on PI3K/Akt signaling pathway and TNF-α± associated with collagen-induced arthritis.
TN1511 Cleomiscosin A LDL , Antioxidant , TNF
Cleomiscosin A is derived from Acer okamotoanum leaf and twig and shows inhibitory activity to TNF-α secretion of the mouse peritoneal macrophages. Cleomiscosin A can be used in studies about the prevention of LDL oxidat...
T3000 Magnolol NSC 293099,5,5'-Diallyl-2,2'-biphenyldiol NF-κB , Retinoid Receptor , Antibacterial , PPAR , p53 , Autophagy
Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks TNF-α-induced NF-KB activation.
TN7235 4-methoxylonchocarpin TNF , NF-κB
4-methoxylonchocarpin was isolated from the roots of Abrus precatorius as a potent anti-inflammatory compound. 4-methoxylonchocarpin inhibited NF-κB-activated TNF expression by inhibiting the binding of LPS to TLR4 in ma...
T5754 Kavain NF-κB , GABA Receptor
Kavain, a compound extracted from the Kava plant, Piper methysticum, is found to be involved in TNF-α expression in human and mouse cells via regulation of transcriptional factors such as NF-kB and LITAF.
T5785 MALTOTETRAOSE Fujioligo 450,Amylotetraose,α-1,4-Tetraglucose TNF , Endogenous Metabolite
Maltotetraose (Fujioligo 450) are potent inhibitors of TNF-α-induced intercellular adhesion molecule-1 (ICAM-1) expression, maltotetraose may be beneficial in the suppression of early atherosclerosis development.
T0610 Piceatannol trans-Piceatannol,Astringenin Apoptosis , Serine/threonin kinase , PKA , Syk , PKC , Autophagy
Piceatannol (Astringenin) is an anti-inflammatory, immunomodulatory and antiproliferative agent. It inhibits p56lck and syk protein tyrosine kinases and inhibits NF-κB activation and gene expression of TNF-induced. It is...
TN6967 (R)-Isomucronulatol (-)-Isomucronulatol,2H-1-Benzopyran-7-ol Apoptosis
(R)-Isomucronulatol (2H-1-Benzopyran-7-ol), a flavonoid that can be extracted from the leaves of Astragalus membranaceus, Sophora japonica, Sclerotium tigrinum, and Glycyrrhiza glabra, inhibits the proliferation and apop...
T3927 Phellopterin GABA Receptor
Phellopterin is a partial agonist of the central benzodiazepine receptors in vitro. Phellopterin shows a cytotoxic effect on RAW264.7 cell at the concentration from 40 to 400 μM. Phellopterin reduce TNF-alpha-induced VCA...
T3805 Prim-O-glucosylcimifugin Cimifugin beta-D-glucopyranoside,Cimifugin 7-glucoside TNF , COX , JAK , NO Synthase
Prim-O-glucosylcimifugin (Cimifugin 7-glucoside) can inhibit the proliferation of SMC(smooth muscle cell) stimulated by TNF-alpha, increase the proportion of G0/G1 phase.
T3662 Eleutheroside E NF-κB
Eleutheroside E has anti-inflammatory effects by inhibiting NF-κB activities. Eleutheroside E significantly decreases the inflammatory cell infiltration, pannus formation, cartilage damage, bone erosion of CIA mice, the ...
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Natural Products

Geraniin
T6S2099
Synonym:
Target: Antioxidant, TNF
Hypaconitine
T6S0630
Synonym:
Target: P450, TNF
HOMOPLANTAGININ
T4S0217
Synonym:
Target: TNF, NF-κB
Sauchinone
T6S1572
Synonym:
Target: ERK, p38 MAPK, NF-κB
Mulberroside A
T6S1597
Synonym:
Target: TNF, Tyrosinase, Interleukin
Muscone
T2893
Synonym: 3-Methylcyclopentadecanone,Methylexaltone
Target: MMP, TNF, NF-κB, NOD-like Receptor (NLR), P-gp, Interleukin
Mesaconitine
T6S0627
Synonym:
Target: TNF
Fisetin
T2879
Synonym:
Target: TNF, Sirtuin, PPAR
Forsythoside B
T3893
Synonym:
Target: TNF, NF-κB
Sinensetin
T4S0227
Synonym: Pedalitin permethyl ether
Target: TNF, PGE Synthase
L-741626
T15686
Synonym: 3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole
Target: Dopamine Receptor
1,4-Dicaffeoylquinic acid
T4S1521
Synonym:
Target: HIV Protease
Ginsenoside Rc
T2720
Synonym: Panaxoside Rc
Target: Others, TNF, GABA Receptor, Interleukin
Tryptanthrin
T7786
Synonym:
Target: DNA gyrase
2'-FUCOSYLLACTOSE
TN6796
Synonym: 2'-Fucosyl-D-lactose
Target: Others
Negletein
T2S0843
Synonym: 7-O-Methylbaicalein,Baicalein-7-methylether
Target: IL Receptor, TNF, NOS, Interleukin
Taurochenodeoxycholic Acid
T2A2481
Synonym: Chenodeoxycholyltaurine,TCDCA,Chenyltaurine,Taurochenodeoxycholate,12-Deoxycholyltaurine
Target: Apoptosis, TNF, Caspase, Endogenous Metabolite
Manghaslin
TN2130
Synonym: Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside
Target: AChE, Glucosidase
Damascenone
T2P2870
Synonym: trans-damascenone,Beta-Damascenone
Target: Others, NF-κB, Endogenous Metabolite
Madecassic acid
T2758
Synonym: 6-Deoxy-L-Galactose,L-Fucose,Brahmic acid,L-fucopyranose
Target: Others, TNF, COX, NO Synthase, Interleukin
Astilbin
T2794
Synonym: Neoastilbin,Taxifolin 3-O-rhamnoside,Isoastilbin,Taxifolin 3-rhamnoside,Neoisoastilbin
Target: TNF, NF-κB, Nrf2
p-Coumaric Acid Ethyl Ester
T13808
Synonym: Ethyl (E)-p-hydroxycinnamate,Ethyl trans-4-hydroxycinnamate
Target: Others, Drug Metabolite
Taurochenodeoxycholic acid sodium
TN2215
Synonym: Sodium taurochenodeoxycholate
Target: Apoptosis, Endogenous Metabolite
Neochlorogenic acid
T6S1538
Synonym: trans-5-O-Caffeoylquinic acid,Neochlorogenate,5-O-Caffeoylquinic acid
Target: TNF, NF-κB, COX, Antibacterial, Interleukin
7,3',4'-Tri-O-methylluteolin
TN1291
Synonym: 5-Hydroxy-3',4',7-trimethoxyflavone
Target: TNF, COX, Interleukin
Shikonin
T1125
Synonym: NSC 252844,Isoarnebin 4,(+)-Shikonin,Alkanna Red,C.I. 75535,Anchusa acid
Target: TNF, NF-κB, Chloride channel, HIV Protease, PKM
2,5-Dihydroxyacetophenone
TCS2170
Synonym: Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP
Target: ERK, NF-κB, Tyrosinase
Ginsenoside Rh1
T2932
Synonym: Sanchinoside B2,Prosapogenin A2,20(S)-Ginsenoside Rh1,Sanchinoside Rh1
Target: IL Receptor, TNF, Endogenous Metabolite, PPAR, Interleukin
β-Anhydroicaritin
T6S2140
Synonym: Anhydroicaritin,Beta-Anhydroicaritin
Target: MMP, Others, TNF, Interleukin
MOSLOFLAVONE
T5779
Synonym:
Target: IL Receptor, Virus Protease, TNF, Antibacterial
Deoxyandrographolide
TQ0218
Synonym: 14-deoxyandrographolide
Target: IL Receptor, TNF
1beta-Hydroxyalantolactone
TN2539
Synonym:
Target: IL Receptor, TNF
14-Deoxyandrographolide
T8288
Synonym:
Target: Apoptosis, Others
Platycodin D
T3889
Synonym:
Target: Prostaglandin Receptor, AMPK
Compound Lup-20(29)-en-3-yl acetate
TC0036
Synonym:
Target: IL Receptor, VEGFR, Others, TNF, COX
Esculentoside H
T3S1641
Synonym:
Target: TNF, NF-κB, JNK
Isoforskolin
TN1520
Synonym: Coleonol B
Target: IL Receptor, TNF
Rosarin
T3887
Synonym:
Target: Others
Cepharanthine
T0131
Synonym: NSC-623442
Target: Apoptosis, TNF, HIV Protease, Autophagy
Clematichinenoside AR
TN1507
Synonym:
Target: TNF, Autophagy
Cleomiscosin A
TN1511
Synonym:
Target: LDL, Antioxidant, TNF
Magnolol
T3000
Synonym: NSC 293099,5,5'-Diallyl-2,2'-biphenyldiol
Target: NF-κB, Retinoid Receptor, Antibacterial, PPAR, p53, Autophagy
4-methoxylonchocarpin
TN7235
Synonym:
Target: TNF, NF-κB
Kavain
T5754
Synonym:
Target: NF-κB, GABA Receptor
MALTOTETRAOSE
T5785
Synonym: Fujioligo 450,Amylotetraose,α-1,4-Tetraglucose
Target: TNF, Endogenous Metabolite
Piceatannol
T0610
Synonym: trans-Piceatannol,Astringenin
Target: Apoptosis, Serine/threonin kinase, PKA, Syk, PKC, Autophagy
(R)-Isomucronulatol
TN6967
Synonym: (-)-Isomucronulatol,2H-1-Benzopyran-7-ol
Target: Apoptosis
Phellopterin
T3927
Synonym:
Target: GABA Receptor
Prim-O-glucosylcimifugin
T3805
Synonym: Cimifugin beta-D-glucopyranoside,Cimifugin 7-glucoside
Target: TNF, COX, JAK, NO Synthase
Eleutheroside E
T3662
Synonym:
Target: NF-κB

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPJ-00779 TNF alpha Protein, Rabbit, Recombinant Rabbit E. coli
Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor ty...
TMPY-00936 TNF alpha Protein, Human, Recombinant Human E. coli
Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological...
TMPY-01294 TNF alpha Protein, Mouse, Recombinant Mouse E. coli
Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological...
TMPY-04146 TNF alpha Protein, Human, Recombinant (hFc) Human HEK293
Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological...
TMPY-02202 TNF alpha Protein, Rat, Recombinant Rat E. coli
Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological...
TMPY-02153 TNF beta Protein, Human, Recombinant Human E. coli
Lymphotoxin-alpha, also known as LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA TNFSF1, and TNFB, is a secreted protein that belongs to the tumor necrosis factor family. TNF-beta/TNFSF1/Lympho...
TMPY-05187 TNF alpha Protein, Mouse, Recombinant, Biotinylated Mouse E. coli
Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological...
TMPK-00583 TNF alpha Protein, Ferret, Recombinant (His) Ferret E. coli
Tumor necrosis factor alpha (TNF-alpha), also known as cachectin and TNFSF2, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, immune system developm...
TMPK-00119 TNF alpha Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Tumor necrosis factor alpha (TNF-alpha), also known as cachectin and TNFSF2, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, immune system developm...
TMPY-02535 TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (hFc) Mouse HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with th...
TMPJ-00288 TNF RII Protein, Human, Recombinant (mFc) Human Human Cells
Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B) is a member of the tumor necrosis factor receptor superfamily. Human TNF RII contains four cysteinerich repeats in its ECD, which shares 58% and 56% amino a...
TMPK-00120 TNF alpha Protein, Human, Recombinant (His & Avi) Human HEK293
Tumor necrosis factor alpha (TNF-alpha), also known as cachectin and TNFSF2, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, immune system developm...
TMPY-01697 TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (His) Mouse HEK293
Tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B), also known as Tumor necrosis factor receptor 2 (TNFR2) or CD120b antigen, is a member of the tumor necrosis factor receptor superfamily. TNFR2/CD120b/TNFR...
TMPY-05237 TNF alpha Protein, Human, Recombinant, Biotinylated Human E. coli
Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological...
TMPK-00121 TNF alpha Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Tumor necrosis factor alpha (TNF-alpha), also known as cachectin and TNFSF2, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, immune system developm...
TMPJ-00287 TNF RII Protein, Human, Recombinant (hFc) Human Human Cells
Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B) is a member of the tumor necrosis factor receptor superfamily. Human TNF RII contains four cysteinerich repeats in its ECD, which shares 58% and 56% amino a...
TMPJ-00125 TNF alpha Protein, Human, Recombinant (aa 57-233, His) Human E. coli
Tumor Necrosis Factor-α (TNF-α) is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells following stimulation by bacterial LPS. Cells expressing CD4 secrete TNF-α while cells that express CD8 secrete li...
TMPJ-00124 TNF alpha Protein, Human, Recombinant (aa 77-233, His) Human E. coli
Tumor Necrosis Factor-α (TNF-α) is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells following stimulation by bacterial LPS. Cells expressing CD4 secrete TNF-α while cells that express CD8 secrete li...
TMPY-02226 TNF alpha Protein, Ferret, Recombinant Ferret E. coli
Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological...
TMPY-01594 TNF alpha Protein, Canine, Recombinant Canine E. coli
Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological...
TMPY-02069 TNF alpha Protein, Cynomolgus, Rhesus, Recombinant Cynomolgus,Rhesus E. coli
Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological...
TMPY-05516 TNF alpha Protein, Cynomolgus, Recombinant, Biotinylated Cynomolgus E. coli
Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological...
TMPY-03203 CD40 Protein, Rat, Recombinant (His) Rat HEK293
CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory...
TMPY-01459 TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with th...
TMPY-01166 TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His) Human HEK293
Tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B), also known as Tumor necrosis factor receptor 2 (TNFR2) or CD120b antigen, is a member of the tumor necrosis factor receptor superfamily. TNFR2/CD120b/TNFR...
TMPY-01181 CD40 Protein, Human, Recombinant (His) Human HEK293
CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory...
TMPJ-01391 BAFF/TNFSF13B Protein, Mouse, Recombinant (mFc) Mouse Human Cells
TNFSF13B/TNFSF20 belongs to the tumor necrosis factor family. It abundantly is expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. Also found in the spleen, lymph node, bo...
TMPJ-00137 APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His) Human Human Cells
APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to relea...
TMPJ-00280 TNF R1 Protein, Mouse, Recombinant Mouse E. coli
Tumor necrosis factor receptor superfamily member 1A (Tnfrsf1a) is a member of the tumor necrosis factor receptor superfamily. Tnfrsf1a is one of the major receptors for the tumor necrosis factor-alpha. It can activate t...
TMPH-01620 TNF beta Protein, Human, Recombinant (His) Human HEK293
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Negativ...
TMPH-02770 TNF beta Protein, Mouse, Recombinant (His) Mouse E. coli
Sialidases have been suggested to be pathogenic factors in microbial infections.
TMPJ-00603 TL1A Protein, Mouse, Recombinant Mouse E. coli
Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-specific gene, and recombinant TNFSF15 is a potent inhibitor ...
TMPY-05957 CD40 Protein, Mouse, Recombinant (His) Mouse HEK293
CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory...
TMPH-03745 TNF-alpha Protein, Zebrafish, Recombinant (His) Danio rerio (Zebrafish) E. coli
TMPY-01696 TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (hFc) Mouse HEK293
Tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B), also known as Tumor necrosis factor receptor 2 (TNFR2) or CD120b antigen, is a member of the tumor necrosis factor receptor superfamily. TNFR2/CD120b/TNFR...
TMPY-01639 TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (His) Mouse HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with th...
TMPK-01382 TNFR2/CD120b/TNFR1B Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Tumor Necrosis Factor Receptor II (TNF RII), also known as TNFRSF1B, p75/p80, and CD120b, is a type I transmembrane protein that belongs to the TNF receptor superfamily. It has a molecular weight of approximately 75 kDa....
TMPJ-00618 TNF RII Protein, Rhesus macaque, Recombinant (hFc) Rhesus Macaque Human Cells
Tumor Necrosis Factor Receptor Superfamily Member 1B (TNFRSF1B) is a member of the Tumor Necrosis Factor Receptor Superfamily. TNFRSF1B contains four TNFR-Cys repeats. TNFRSF1B can be cleaved into the following 2 chains:...
TMPJ-00619 TNF RII Protein, Rhesus macaque, Recombinant (His) Rhesus Macaque Human Cells
Tumor Necrosis Factor Receptor Superfamily Member 1B (TNFRSF1B) is a member of the Tumor Necrosis Factor Receptor Superfamily. TNFRSF1B contains four TNFR-Cys repeats. TNFRSF1B can be cleaved into the following 2 chains:...
TMPK-00564 TNFR1/CD120a/TNFRSF1A Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Tumour necrosis factor alpha (TNF-α) is a pleiotropic cytokine with both injurious and protective functions, which are thought to diverge at the level of its two cell surface receptors, TNFR1 and TNFR2. In the setting of...
TMPJ-00296 TNF RII Protein, Mouse, Recombinant (His & Avi), Biotinylated Mouse Human Cells
Tumor Necrosis Factor Receptor Superfamily Member 1B (TNFRSF1B) is a member of the Tumor Necrosis Factor Receptor Superfamily. TNFRSF1B contains four TNFR-Cys repeats. TNFRSF1B can be cleaved into the following 2 chains:...
TMPY-00248 Lymphotoxin Beta Protein, Cynomolgus, Recombinant (His) Cynomolgus Baculovirus-Insect Cells
LTB (Lymphotoxin Beta) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surfa...
TMPY-03907 CD40 Protein, Canine, Recombinant (hFc) Canine HEK293
CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory...
TMPY-03944 CD40 Protein, Canine, Recombinant Canine HEK293
CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory...
TMPY-04089 CD40 Protein, Canine, Recombinant (His) Canine HEK293
CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory...
TMPY-03212 CD40 Protein, Rhesus, Recombinant (His) Rhesus HEK293
CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory...
TMPY-03083 CD40 Protein, Rat, Recombinant (hFc) Rat HEK293
CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory...
TMPY-03211 CD40 Protein, Rhesus, Recombinant (hFc) Rhesus HEK293
CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory...
TMPJ-00607 RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His) Mouse Human Cells
Mouse tumor necrosis factor ligand superfamily member 11(Tnfsf11) is a member of the tumor necrosis factor (TNF) cytokine family. Tnfsf11 is widely expressed in cells including T cells and T cell rich organs, such as thy...
TMPY-06600 TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B), also known as Tumor necrosis factor receptor 2 (TNFR2) or CD120b antigen, is a member of the tumor necrosis factor receptor superfamily. TNFR2/CD120b/TNFR...
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TNF alpha Protein, Rabbit, Recombinant
TMPJ-00779
Species: Rabbit
Expression System: E. coli
TNF alpha Protein, Human, Recombinant
TMPY-00936
Species: Human
Expression System: E. coli
TNF alpha Protein, Mouse, Recombinant
TMPY-01294
Species: Mouse
Expression System: E. coli
TNF alpha Protein, Human, Recombinant (hFc)
TMPY-04146
Species: Human
Expression System: HEK293
TNF alpha Protein, Rat, Recombinant
TMPY-02202
Species: Rat
Expression System: E. coli
TNF beta Protein, Human, Recombinant
TMPY-02153
Species: Human
Expression System: E. coli
TNF alpha Protein, Mouse, Recombinant, Biotinylated
TMPY-05187
Species: Mouse
Expression System: E. coli
TNF alpha Protein, Ferret, Recombinant (His)
TMPK-00583
Species: Ferret
Expression System: E. coli
TNF alpha Protein, Cynomolgus, Recombinant (His)
TMPK-00119
Species: Cynomolgus
Expression System: HEK293
TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (hFc)
TMPY-02535
Species: Mouse
Expression System: HEK293
TNF RII Protein, Human, Recombinant (mFc)
TMPJ-00288
Species: Human
Expression System: Human Cells
TNF alpha Protein, Human, Recombinant (His & Avi)
TMPK-00120
Species: Human
Expression System: HEK293
TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (His)
TMPY-01697
Species: Mouse
Expression System: HEK293
TNF alpha Protein, Human, Recombinant, Biotinylated
TMPY-05237
Species: Human
Expression System: E. coli
TNF alpha Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00121
Species: Human
Expression System: HEK293
TNF RII Protein, Human, Recombinant (hFc)
TMPJ-00287
Species: Human
Expression System: Human Cells
TNF alpha Protein, Human, Recombinant (aa 57-233, His)
TMPJ-00125
Species: Human
Expression System: E. coli
TNF alpha Protein, Human, Recombinant (aa 77-233, His)
TMPJ-00124
Species: Human
Expression System: E. coli
TNF alpha Protein, Ferret, Recombinant
TMPY-02226
Species: Ferret
Expression System: E. coli
TNF alpha Protein, Canine, Recombinant
TMPY-01594
Species: Canine
Expression System: E. coli
TNF alpha Protein, Cynomolgus, Rhesus, Recombinant
TMPY-02069
Species: Cynomolgus,Rhesus
Expression System: E. coli
TNF alpha Protein, Cynomolgus, Recombinant, Biotinylated
TMPY-05516
Species: Cynomolgus
Expression System: E. coli
CD40 Protein, Rat, Recombinant (His)
TMPY-03203
Species: Rat
Expression System: HEK293
TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His)
TMPY-01459
Species: Human
Expression System: HEK293
TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His)
TMPY-01166
Species: Human
Expression System: HEK293
CD40 Protein, Human, Recombinant (His)
TMPY-01181
Species: Human
Expression System: HEK293
BAFF/TNFSF13B Protein, Mouse, Recombinant (mFc)
TMPJ-01391
Species: Mouse
Expression System: Human Cells
APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His)
TMPJ-00137
Species: Human
Expression System: Human Cells
TNF R1 Protein, Mouse, Recombinant
TMPJ-00280
Species: Mouse
Expression System: E. coli
TNF beta Protein, Human, Recombinant (His)
TMPH-01620
Species: Human
Expression System: HEK293
TNF beta Protein, Mouse, Recombinant (His)
TMPH-02770
Species: Mouse
Expression System: E. coli
TL1A Protein, Mouse, Recombinant
TMPJ-00603
Species: Mouse
Expression System: E. coli
CD40 Protein, Mouse, Recombinant (His)
TMPY-05957
Species: Mouse
Expression System: HEK293
TNF-alpha Protein, Zebrafish, Recombinant (His)
TMPH-03745
Species: Danio rerio (Zebrafish)
Expression System: E. coli
TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (hFc)
TMPY-01696
Species: Mouse
Expression System: HEK293
TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (His)
TMPY-01639
Species: Mouse
Expression System: HEK293
TNFR2/CD120b/TNFR1B Protein, Cynomolgus, Recombinant (His)
TMPK-01382
Species: Cynomolgus
Expression System: HEK293
TNF RII Protein, Rhesus macaque, Recombinant (hFc)
TMPJ-00618
Species: Rhesus Macaque
Expression System: Human Cells
TNF RII Protein, Rhesus macaque, Recombinant (His)
TMPJ-00619
Species: Rhesus Macaque
Expression System: Human Cells
TNFR1/CD120a/TNFRSF1A Protein, Cynomolgus, Recombinant (His)
TMPK-00564
Species: Cynomolgus
Expression System: HEK293
TNF RII Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPJ-00296
Species: Mouse
Expression System: Human Cells
Lymphotoxin Beta Protein, Cynomolgus, Recombinant (His)
TMPY-00248
Species: Cynomolgus
Expression System: Baculovirus-Insect Cells
CD40 Protein, Canine, Recombinant (hFc)
TMPY-03907
Species: Canine
Expression System: HEK293
CD40 Protein, Canine, Recombinant
TMPY-03944
Species: Canine
Expression System: HEK293
CD40 Protein, Canine, Recombinant (His)
TMPY-04089
Species: Canine
Expression System: HEK293
CD40 Protein, Rhesus, Recombinant (His)
TMPY-03212
Species: Rhesus
Expression System: HEK293
CD40 Protein, Rat, Recombinant (hFc)
TMPY-03083
Species: Rat
Expression System: HEK293
CD40 Protein, Rhesus, Recombinant (hFc)
TMPY-03211
Species: Rhesus
Expression System: HEK293
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His)
TMPJ-00607
Species: Mouse
Expression System: Human Cells
TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06600
Species: Human
Expression System: HEK293
Cat No. Product Name
L4700 Immunology/Inflammation Compound Library

3483 compounds
A unique collection of 3483 anti-inflammation compounds effective for high throughput screening and high content screening.
L3800 NF-κB Signaling Compound Library

740 compounds
A unique collection of 740 compounds targeting NF-κB signaling for high throughput screening and high content screening;
L9810 Anti-Fibrosis Compound Library

1180 compounds
A unique collection of 1180 potential anti-fibrosis compounds, can be used in HTS and HCS;
L3600 Cytokine Inhibitor Library

613 compounds
A unique collection of 613 compounds targeting cytokine signaling for high throughput screening and high content screening for drug discovery;
L9840 Anti-Alzheimer's Disease Compound Library

1040 compounds
A unique collection of 1040 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS.
TargetMol