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Search Results for "egfr"

Targets

Libraries

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Compounds

Cat No. Product Name
T21954 EGFR/ErbB-2/ErbB-4 inhibitor-2 EGFR/ErbB2 Inhibitor EGFR
EGFR/ErbB2 Inhibitor is a cell-permeable inhibitor of EGFR and c-ErbB2 (IC50s = 20 and 79 nM, respectively)
T60076 Oritinib SH-1028 EGFR
Oritinib is an inhibitor of EGFR with IC50s of 18, 0.7, 4, 0.1, 1.4 and 0.89 nM for EGFR (wt), EGFR (L858R), EGFR (L861Q...
T6039 TAK-285 TAK 285 , TAK285 EGFR , MEK , HER , Aurora Kinase
TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor with IC50 of 17 nM and 23 nM, >10-fold selectivity for HER1/2 than...
TQ0166 Tesevatinib XL-647 , EXEL-7647 , KD-019 VEGFR , EGFR , FLT , Ephrin Receptor
Tesevatinib is an orally available, multi-target tyrosine kinase inhibitor (IC50s: 0.3, 16, 1.5, 8.7, and 1.4 nM for EGF...
T39275 Befotertinib D-0316 EGFR
Befotertinib is an inhibitor of EGFR tyrosine kinase and can be used for studies about EGFR T790M-positive non-small cel...
T4694 AG-1557 hydrochloride (189290-58-2(free base)) HER , EGFR
AG-1557 is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: 8.194).
T60064 WAY-270360 N-[4-(1H-benzimidazol-2-yl)phenyl]-2,4-dimethoxybenzamide Sirtuin , EGFR
WAY-270360 is a sirtuin modulator and an epidermal growth factor receptor (EGFR) inhibitor.
T8758 Poziotinib hydrochloride HM 781-36B hydrochloride , NOV120101 hydrochloride EGFR
Poziotinib hydrochloride irreversibly inhibits EGFR (HER1 or ErbB1), including EGFR mutants, HER2, and HER4, thereby inh...
T4657L WHI-P97 HCl 211555-05-4(free base) JAK
WHI-P97 HCl is a potent and selective JAK-3 inhibitor. WHI-P97 had an estimated Ki value of 0.09 microM from modeling st...
T9754 BLU-945 BLU 945 , BLU945 EGFR
BLU-945 is a potent, highly selective, reversible and orally active inhibitor of epidermal growth factor receptor (EGFR...
T4S0544 Furanodienone Apoptosis , HER
1. Furanodienone has effects on MCF-7 cells are mediated, at least in part, by inhibiting ERα signaling. 2. Furanodienon...
T60108 PDGFR Tyrosine Kinase Inhibitor III PDGF Receptor Tyrosine Kinase Inhibitor III PDGFR
PDGFR Tyrosine Kinase Inhibitor III (PDGF Receptor Tyrosine Kinase Inhibitor III), a multikinase inhibitor, inhibits PDG...
T2496 (Z)-Semaxinib SU5416 VEGFR
Semaxanib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor (IC50: 1.23 μM), 20-fold more selective for VEGF...
T6982 SGI-7079 c-RET , c-Met/HGFR , FLT , TAM Receptor , Src
SGI-7079 is a new selective Axl inhibitor. SGI-7079 can be a dose-dependent manner inhibited growth of tumors. It is als...
T35528L TD52 dihydrochloride TD52 dihydrochloride(1798328-24-1 Free base) , TD52 2HCl Others
TD52 dihydrochloride, an Erlotinib derivative, is an orally active, potent cancerous inhibitor of protein phosphatase 2A...
T21723L Epidermal Growth Factor Receptor Peptide Acetate Epidermal Growth Factor Receptor Peptide Acetate(96249-43-3 Free base) Others
Epidermal Growth Factor Receptor Peptide exists on the cell surface and is activated by the binding of its specific liga...
T9912 Trastuzumab EGFR
Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2. Trastuzu...
T22974 Methyl 2,5-dihydroxycinnamate EGFR
EGF receptor-associated tyrosine kinases inhibitor
T3466 FIIN-3 EGFR , FGFR
FIIN-3 is an irreversible inhibitor of FGFR.
EGFR/ErbB-2/ErbB-4 inhibitor-2
T21954
synonym: EGFR/ErbB2 Inhibitor
Target:
Oritinib
T60076
synonym: SH-1028
Target:
TAK-285
T6039
synonym: TAK 285 , TAK285
Target:
Tesevatinib
TQ0166
synonym: XL-647 , EXEL-7647 , KD-019
Target:
Befotertinib
T39275
synonym: D-0316
Target:
AG-1557 hydrochloride (189290-58-2(free base))
T4694
synonym:
Target:
WAY-270360
T60064
synonym: N-[4-(1H-benzimidazol-2-yl)phenyl]-2,4-dimethoxybenzamide
Target:
Poziotinib hydrochloride
T8758
synonym: HM 781-36B hydrochloride , NOV120101 hydrochloride
Target:
WHI-P97 HCl 211555-05-4(free base)
T4657L
synonym:
Target:
BLU-945
T9754
synonym: BLU 945 , BLU945
Target:
Furanodienone
T4S0544
synonym:
Target:
PDGFR Tyrosine Kinase Inhibitor III
T60108
synonym: PDGF Receptor Tyrosine Kinase Inhibitor III
Target:
(Z)-Semaxinib
T2496
synonym: SU5416
Target:
SGI-7079
T6982
synonym:
Target:
TD52 dihydrochloride
T35528L
synonym: TD52 dihydrochloride(1798328-24-1 Free base) , TD52 2HCl
Target:
Epidermal Growth Factor Receptor Peptide Acetate
T21723L
synonym: Epidermal Growth Factor Receptor Peptide Acetate(96249-43-3 Free base)
Target:
Trastuzumab
T9912
synonym:
Target:
Methyl 2,5-dihydroxycinnamate
T22974
synonym:
Target:
FIIN-3
T3466
synonym:
Target:
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