Search Result

Search Results for "egfr"

Targets

Libraries

Clinical Compound Library Anti-Pancreatic Cancer Compound Library Anti-Breast Cancer Compound Library FDA-Approved Kinase Inhibitor Library Kinase Inhibitor Library Covalent Inhibitor Library

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Compounds

Cat No.	Product Name
T21954	EGFR/ErbB-2/ErbB-4 inhibitor-2	EGFR/ErbB2 Inhibitor	EGFR
	EGFR/ErbB2 Inhibitor is a cell-permeable inhibitor of EGFR and c-ErbB2 (IC50s = 20 and 79 nM, respectively)		EGFR
T60076	Oritinib	SH-1028	EGFR
	Oritinib is an inhibitor of EGFR with IC50s of 18, 0.7, 4, 0.1, 1.4 and 0.89 nM for EGFR (wt), EGFR (L858R), EGFR (L861Q...		EGFR
T6039	TAK-285	TAK 285 , TAK285	EGFR , MEK , HER , Aurora Kinase
	TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor with IC50 of 17 nM and 23 nM, >10-fold selectivity for HER1/2 than...		EGFR , MEK , HER , Aurora Kinase
TQ0166	Tesevatinib	XL-647 , EXEL-7647 , KD-019	VEGFR , EGFR , FLT , Ephrin Receptor
	Tesevatinib is an orally available, multi-target tyrosine kinase inhibitor (IC50s: 0.3, 16, 1.5, 8.7, and 1.4 nM for EGF...		VEGFR , EGFR , FLT , Ephrin Receptor
T39275	Befotertinib	D-0316	EGFR
	Befotertinib is an inhibitor of EGFR tyrosine kinase and can be used for studies about EGFR T790M-positive non-small cel...		EGFR
T4694	AG-1557 hydrochloride (189290-58-2(free base))		HER , EGFR
	AG-1557 is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: 8.194).		HER , EGFR
T60064	WAY-270360	N-[4-(1H-benzimidazol-2-yl)phenyl]-2,4-dimethoxybenzamide	Sirtuin , EGFR
	WAY-270360 is a sirtuin modulator and an epidermal growth factor receptor (EGFR) inhibitor.		Sirtuin , EGFR
T8758	Poziotinib hydrochloride	HM 781-36B hydrochloride , NOV120101 hydrochloride	EGFR
	Poziotinib hydrochloride irreversibly inhibits EGFR (HER1 or ErbB1), including EGFR mutants, HER2, and HER4, thereby inh...		EGFR
T4657L	WHI-P97 HCl 211555-05-4(free base)		JAK
	WHI-P97 HCl is a potent and selective JAK-3 inhibitor. WHI-P97 had an estimated Ki value of 0.09 microM from modeling st...		JAK
T9754	BLU-945	BLU 945 , BLU945	EGFR
	BLU-945 is a potent, highly selective, reversible and orally active inhibitor of epidermal growth factor receptor (EGFR...		EGFR
T4S0544	Furanodienone		Apoptosis , HER
	1. Furanodienone has effects on MCF-7 cells are mediated, at least in part, by inhibiting ERα signaling. 2. Furanodienon...		Apoptosis , HER
T60108	PDGFR Tyrosine Kinase Inhibitor III	PDGF Receptor Tyrosine Kinase Inhibitor III	PDGFR
	PDGFR Tyrosine Kinase Inhibitor III (PDGF Receptor Tyrosine Kinase Inhibitor III), a multikinase inhibitor, inhibits PDG...		PDGFR
T2496	(Z)-Semaxinib	SU5416	VEGFR
	Semaxanib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor (IC50: 1.23 μM), 20-fold more selective for VEGF...		VEGFR
T6982	SGI-7079		c-RET , c-Met/HGFR , FLT , TAM Receptor , Src
	SGI-7079 is a new selective Axl inhibitor. SGI-7079 can be a dose-dependent manner inhibited growth of tumors. It is als...		c-RET , c-Met/HGFR , FLT , TAM Receptor , Src
T35528L	TD52 dihydrochloride	TD52 dihydrochloride(1798328-24-1 Free base) , TD52 2HCl	Others
	TD52 dihydrochloride, an Erlotinib derivative, is an orally active, potent cancerous inhibitor of protein phosphatase 2A...		Others
T21723L	Epidermal Growth Factor Receptor Peptide Acetate	Epidermal Growth Factor Receptor Peptide Acetate(96249-43-3 Free base)	Others
	Epidermal Growth Factor Receptor Peptide exists on the cell surface and is activated by the binding of its specific liga...		Others
T9912	Trastuzumab		EGFR
	Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2. Trastuzu...		EGFR
T22974	Methyl 2,5-dihydroxycinnamate		EGFR
	EGF receptor-associated tyrosine kinases inhibitor		EGFR
T3466	FIIN-3		EGFR , FGFR
	FIIN-3 is an irreversible inhibitor of FGFR.		EGFR , FGFR