T21954 |
EGFR/ErbB-2/ErbB-4 inhibitor-2
|
EGFR/ErbB2 Inhibitor |
EGFR
|
|
EGFR/ErbB2 Inhibitor is a cell-permeable inhibitor of EGFR and c-ErbB2 (IC50s = 20 and 79 nM, respectively) |
T60076 |
Oritinib
|
SH-1028 |
EGFR
|
|
Oritinib is an inhibitor of EGFR with IC50s of 18, 0.7, 4, 0.1, 1.4 and 0.89 nM for EGFR (wt), EGFR (L858R), EGFR (L861Q... |
T6039 |
TAK-285
|
TAK 285 , TAK285 |
EGFR
,
MEK
,
HER
,
Aurora Kinase
|
|
TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor with IC50 of 17 nM and 23 nM, >10-fold selectivity for HER1/2 than... |
TQ0166 |
Tesevatinib
|
XL-647 , EXEL-7647 , KD-019 |
VEGFR
,
EGFR
,
FLT
,
Ephrin Receptor
|
|
Tesevatinib is an orally available, multi-target tyrosine kinase inhibitor (IC50s: 0.3, 16, 1.5, 8.7, and 1.4 nM for EGF... |
T39275 |
Befotertinib
|
D-0316 |
EGFR
|
|
Befotertinib is an inhibitor of EGFR tyrosine kinase and can be used for studies about EGFR T790M-positive non-small cel... |
T4694 |
AG-1557 hydrochloride (189290-58-2(free base))
|
|
HER
,
EGFR
|
|
AG-1557 is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: 8.194). |
T60064 |
WAY-270360
|
N-[4-(1H-benzimidazol-2-yl)phenyl]-2,4-dimethoxybenzamide |
Sirtuin
,
EGFR
|
|
WAY-270360 is a sirtuin modulator and an epidermal growth factor receptor (EGFR) inhibitor. |
T8758 |
Poziotinib hydrochloride
|
HM 781-36B hydrochloride , NOV120101 hydrochloride |
EGFR
|
|
Poziotinib hydrochloride irreversibly inhibits EGFR (HER1 or ErbB1), including EGFR mutants, HER2, and HER4, thereby inh... |
T4657L |
WHI-P97 HCl 211555-05-4(free base)
|
|
JAK
|
|
WHI-P97 HCl is a potent and selective JAK-3 inhibitor. WHI-P97 had an estimated Ki value of 0.09 microM from modeling st... |
T9754 |
BLU-945
|
BLU 945 , BLU945 |
EGFR
|
|
BLU-945 is a potent, highly selective, reversible and orally active inhibitor of epidermal growth factor receptor (EGFR... |
T4S0544 |
Furanodienone
|
|
Apoptosis
,
HER
|
|
1. Furanodienone has effects on MCF-7 cells are mediated, at least in part, by inhibiting ERα signaling. 2. Furanodienon... |
T60108 |
PDGFR Tyrosine Kinase Inhibitor III
|
PDGF Receptor Tyrosine Kinase Inhibitor III |
PDGFR
|
|
PDGFR Tyrosine Kinase Inhibitor III (PDGF Receptor Tyrosine Kinase Inhibitor III), a multikinase inhibitor, inhibits PDG... |
T2496 |
(Z)-Semaxinib
|
SU5416 |
VEGFR
|
|
Semaxanib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor (IC50: 1.23 μM), 20-fold more selective for VEGF... |
T6982 |
SGI-7079
|
|
c-RET
,
c-Met/HGFR
,
FLT
,
TAM Receptor
,
Src
|
|
SGI-7079 is a new selective Axl inhibitor. SGI-7079 can be a dose-dependent manner inhibited growth of tumors. It is als... |
T35528L |
TD52 dihydrochloride
|
TD52 dihydrochloride(1798328-24-1 Free base) , TD52 2HCl |
Others
|
|
TD52 dihydrochloride, an Erlotinib derivative, is an orally active, potent cancerous inhibitor of protein phosphatase 2A... |
T21723L |
Epidermal Growth Factor Receptor Peptide Acetate
|
Epidermal Growth Factor Receptor Peptide Acetate(96249-43-3 Free base) |
Others
|
|
Epidermal Growth Factor Receptor Peptide exists on the cell surface and is activated by the binding of its specific liga... |
T9912 |
Trastuzumab
|
|
EGFR
|
|
Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2. Trastuzu... |
T22974 |
Methyl 2,5-dihydroxycinnamate
|
|
EGFR
|
|
EGF receptor-associated tyrosine kinases inhibitor |
T3466 |
FIIN-3
|
|
EGFR
,
FGFR
|
|
FIIN-3 is an irreversible inhibitor of FGFR. |