5,6-dehydro arachidonic acid

5,6-dehydro Arachidonic acid is an analog of arachidonic acid with an acetylene in the 5,6 position. It inhibits 5-LO in rat basophilic leukemia cells, with a Ki value of 15 μM. In guinea pig leukocytes, 5-LO is inhibited by 5,6-dehydro arachidonic acid with an IC50 value of 10 μM.

5-Methyltetrahydrofolic acid (5-Methyl THF) is a biologically active form of folic acid and a methylated derivate of tetrahydrofolate. It is the predominant natural dietary folate and the principal form of folate in plasma and cerebrospinal fluid.

5'-Guanylic acid disodium salt (GMP-5) belongs to the class of organic compounds known as purine ribonucleoside monophosphates. In particular, L-Glutamic acid and guanosine monophosphate can be biosynthesized from xanthylic acid and L-glutamine; which is catalyzed by the enzyme GMP synthase [glutamine-hydrolyzing]. In addition, Guanosine triphosphate and guanosine monophosphate can be biosynthesized from diguanosine tetraphosphate; which is catalyzed by the enzyme bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]. In humans, guanosine monophosphate is involved in the kanamycin action pathway, the telithromycin action pathway, the tobramycin action pathway, and the erythromycin action pathway. Guanosine monophosphate is also involved in several metabolic disorders, some of which include the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and the 2-hydroxyglutric aciduria (D and L form) pathway. Outside of the human body, guanosine monophosphate can be found in a number of food items such as onion-family vegetables, millet, chinese water chestnut, and red rice. This makes guanosine monophosphate a potential biomarker for the consumption of these food products.

5-Aminosalicylic Acid (5-ASA) is an anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE.

Compound Fr12564 is a useful organic compound for research related to life sciences. The catalog number is Fr12564 and the CAS number is 3438-16-2.

2-chloro-5-(16,18-dioxo-17-azapentacyclo[6.6.5.0~2,7~.0~9,14~.0~15,19~]nonadeca-2,4,6,9,11,13-hexaen-17-yl)benzoic acid can be used to synthesize a variety of organic compounds.

5,6-DIAMINOPYRIDINE-3-CARBOXYLIC ACID METHYL ESTER is a useful organic compound for research related to life sciences. The catalog number is T9829 and the CAS number is 104685-76-9.

5-Acetylsalicylic acid (5-acetyl-2-hydroxybenzoic acid) has anti-inflammatory effects and can be used to treat inflammatory bowel disease, including ulcerative colitis, inflamed anus or rectum, and to maintain remission in Crohn's disease.

3-Amino-5-Hydroxybenzoic Acid (3-amino-5-hydroxy-benzoic acid) is a marine derived natural products found in Salinispora arenicola.

2,3,4-Trifluoro-5-Nitro-Benzoic Acid is a useful intermediate in organic synthesis. It has been used to study the effect of fluorine substitution on the reactivity of organic molecules. It has also been used to study the effect of nitro substitution on the reactivity of organic molecules.

2,3-Dihydro-5-benzofuranacetic Acid is used as Pharmaceutical material and intermeidates.

5,6-dibromo-1H-indole-3-carboxylic acid (5,6-dibromo-1H-indole-3-carboxylicAcid) is a marine derived natural products found in Smenospongia sp.

5-Chloroanthranilic Acid is a metabolite of the pesticide Chlordimeform. It can be used in the preparation of disease-modifying antirheumatic drugs (DMARDs).

Quilseconazole Formic acid is a selective inhibitor of fungal Cyp51 with potent activities against Cryptococcus neoformans and Cryptococcus gattii.

4-[(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]benzoic acid is a synthetic compound with potent antitumor activity, high efficiency and selectivity against tumor cells. However, it has poor solubility in water and is potentially toxic at high concentrations.

4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-carboxylic acid is used as a pharmaceutical intermediate.

4-Amino-5-Chloro-2-Methoxybenzoic Acid (Metoclopramide EP Impurity C) is a Metoclopramide metabolite.

1-(2,3-DIHYDRO-BENZO[1,4]DIOXIN-6-YL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID targets GRK2.

Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)- is a dual PPARα/γ agonist with EC50 of 0.358μM and 1.21μM. Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)- is the R-isomer of Aleglitazar.

Compound 5936-0108 may has modulationg effect on β-Amyloid.

2-Methoxy-5-sulfamoylbenzoic Acid is a metabolite of the antipsychotic drug, Sulpiride.

5-O-Cinnamoylquinic acid is a nature product.

Arachidonic acid (Immunocytophyte) is an unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. It is formed by the synthesis from dietary linoleic acid and is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes.

5-Aminolevulinic acid hydrochloride (5-ALA) serves as an intermediate in the body's heme biosynthesis and is the universal precursor of tetrapyrroles.

(4R,4aS,5aS,6aR,6bS,7aR)-4-Hydroxy-3,6b-dimethyl-5-methylene-4,4a,5,5a,6,6a,7,7a-octahydrocyclopropa[2,3]indeno[5,6-b]furan-2(6bH)-one is a sesquiterpene lactone featuring a complex bicyclic structure [1].

4-(3-Methyl-5-oxo-2-pyrazolin-1-yl)benzoic acid exhibits hypoglycemic activity and operates through a mechanism dependent on the response to oral glucose overload.

3,4, 5-trimethoxyphenylacetic acid is a common intermediate in organic synthesis, and its main use is to convert its carboxyl groups to corresponding applications.

2,4-Dihydroxypyrimidine-5-carboxylic acid (Isoorotic acid) has been obtained from 5-formyluracil by the action of enzyme, thymine 7-hydroxylase. 2,4-Dihydroxypyrimidine-5-carboxylic acid has been used to synthesize N1-alkylated uracil derivatives.

5,6-epoxy-13-cis Retinoic Acid is a metabolite of 13-cis retinoic acid.

3α-Acetoxyurs-5:12-dien-24-oic acid, a natural compound, is isolatable from Boswellia sacra Fluckiger [1].

Omega-3 Arachidonic Acid ethyl ester, a rare polyunsaturated fatty acid with limited presence in dietary sources, is crucial for infant growth and development and offers protection against heart disease, blood clots, high blood pressure, and inflammatory and autoimmune disorders. In human platelet membranes, it impedes arachidonyl-CoA synthetase, exhibiting a Ki of 14 μM, and shows similar inhibitory effects on arachidonoyl-CoA synthetase in calf brain extract with an IC50 of roughly 5 μM. The ethyl arachidonate derivative offers enhanced lipophilicity compared to its free acid counterpart.

5-Methoxysalicylic acid (5-MeOSA), a natural product, serves as an effective matrix for oligonucleotide analysis in MALDI MS when used alongside spermine.

5-Oxodecanoic acid is a biochemical. 5-Oxodecanoic acid can be reducced to 5-hydroxydecanoic acid by intact cells of baker's yeast.

(R)-5-Oxopyrrolidine-2-carboxylic acid (D-Pyroglutamic acid) is a cyclic derivative of glutamic acid, physiologically present in mammalian tissues. It has been shown that PCA releases GABA from the cerebral cortex and displays anti-anxiety effects in a simple approach-avoidance conflict situation in the rat. In clinical pharmacology experiments, PCA significantly shortens the plasma half-life of ethanol during acute intoxication.

5-endo-BCN-pentanoic acid, an alkyl chain-based PROTAC linker, facilitates the synthesis of PROTACs[1].

5,6-Desmethylenedioxy-5-methoxyaglalactone is cytotoxic to small cell lung cancer (NCI-H187) cell line. It has antimycobacterial activity against Mycobacterium tuberculosis H(37)Ra.

5-Aminolevulinic acid is an intermediate in heme synthesis which is the first compound in the porphyrin synthesis pathway.It is a photosensitizing agent, an antineoplastic agent and a prodrug.It can also be used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.

Cis-5-Tetradecenoic acid, an intrinsic metabolite found in blood, serves as a research tool for Long Chain 3-Hydroxyacyl CoA Dehydrogenase Deficiency [1] [2].

Latanoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug. Latanoprost is an isopropyl ester, a prodrug form which is converted to latanoprost (free acid) by endogenous esterase enzymes. The free acid form is 200 times more potent than latanoprost as a ligand for the human recombinant FP receptor. 5-trans Latanoprost (free acid) is an isomer of latanoprost (free acid) wherein the double bond between carbons 5 and 6 has been changed from cis (Z) to trans (E). The trans isomer of latanoprost occurs as an impurity in commercial preparations of the bulk drug product. The present compound was prepared primarily as an analytical standard for detection and quantitation of this impurity. From what can be inferred from the study of other trans isomers of F-type prostaglandins, the biological activity of this isomer is likely to be similar to that of the cis isomer. However, there are no specific published reports on the biological activity, and on reducing intraocular pressure in particular, of 5-trans latanoprost.

Mevalonic acid 5-pyrophosphate (also known as 5-Diphosphomevalonic acid) tetralithium is an endogenous metabolite involved in the mevalonate pathway.

all-trans-5,6-epoxy Retinoic Acid can be used in related research in the field of life sciences. Its product number is T36382 and CAS number is 13100-69-1.

Valeric acid, 5-(p-aminophenoxy)- is a bioactive chemical.

3β-hydroxy-5-Cholestenoic Acid is one of the metabolites of cholesterol found in high concentrations (40-80 ng/ml) in human circulation.

5(Z),8(Z),14(Z)-Eicosatrienoic acid is a polyunsaturated fatty acid that can be a substrate for 5-lipoxygenase (5-LO). 5-LO from RBL-1 cells converts this fatty acid to 5-hydroxy-6,8,14-eicosatrienoic acid and 5-hydroperoxy-6,8,14-eicosatrienoic acid. Due to the lack of a double bond at C-11, this particular fatty acid cannot be used in leukotriene A formation.

5-Galloylquinic acid as an index for the baking intensity of oolong teas. It has antioxidant activity.

5-BroMo-1H-pyrrole-2-carboxylic acid (5-Bromopyrrole-2-carboxylic Acid) is a marine derived natural products found in Agelas cerebrum.

(3S,7S)-5,6-Dehydro-4''-de-O-methylcentrolobine is a natural product from Alpinia blepharocalyx.

Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways. Free arachidonic acid is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. Receptor-stimulated release, metabolism, and re-uptake of free arachidonate are all important aspects of cell signalling and inflammation. Arachidonic acid-biotin was designed to allow arachidonic acid to be detected in complexes with protein binding partners such as fatty acid binding proteins (FABPs). It is thus a tool to be used in the general elucidation of the signaling and transport of free arachidonic acid.

Mead acid, a 20-carbon ω-9 polyunsaturated fatty acid, experiences elevated levels in human plasma under conditions of essential fatty acid deficiency. As 1,25(Z),8(Z),11(Z)-Eicosatrienoic Acid methyl ester (Mead acid methyl ester), it frequently serves as a standard for fatty acid analysis, particularly after fatty acids have been transesterified into methyl esters.

9,11-Dehydro-β-boswellic acid is a compound with urease inhibitory activity and acts as an inhibitor of 5-lipoxygenase (5-LO), a critical enzyme in leukotriene biosynthesis.